Ewing sarcoma breakpoint region 1
Encyclopedia
RNA-binding protein EWS is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the EWSR1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

.

Interactions

Ewing sarcoma breakpoint region 1 has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with POU4F1
POU4F1
POU domain, class 4, transcription factor 1 also known as brain-specific homeobox/POU domain protein 3A , homeobox/POU domain protein RDC-1 or Oct-T1 is a protein that in humans is encoded by the POU4F1 gene....

, SF1
SF1 (gene)
Splicing factor 1 also known as zinc finger protein 162 is a protein that in humans is encoded by the SF1 gene.Splicing factor SF1 is involved in the ATP-dependent formation of the spliceosome complex.-Interactions:...

, BARD1
BARD1
BRCA1-associated RING domain protein 1 is a protein that in humans is encoded by the BARD1 gene.-Interactions:BARD1 has been shown to interact with BRE, UBE2D1, CSTF2, BRCC3, RAD51, BCL3, TACC1, Ewing sarcoma breakpoint region 1, FANCD2, H2AFX, CSTF1, NPM1, BRCA2, BRCA1, P53 and Aurora B...

, Small nuclear ribonucleoprotein polypeptide C
Small nuclear ribonucleoprotein polypeptide C
U1 small nuclear ribonucleoprotein C is a protein that in humans is encoded by the SNRPC gene.-Interactions:Small nuclear ribonucleoprotein polypeptide C has been shown to interact with Ewing sarcoma breakpoint region 1.-Further reading:...

, PTK2B
PTK2B
Protein tyrosine kinase 2 beta is an enzyme that in humans is encoded by the PTK2B gene.-Protein:-Interactions:PTK2B has been shown to interact with PTPN11, PTPN6, PITPNM1, Gelsolin, Src, GRIN2A, Ewing sarcoma breakpoint region 1, RB1CC1, TGFB1I1, NPHP1, BCAR1, FYN, DLG4, DLG3, DDEF2, Cbl gene, RAS...

 and Zinc finger protein 165
Zinc finger protein 165
Zinc finger protein 165 is a protein that in humans is encoded by the ZNF165 gene.-Interactions:Zinc finger protein 165 has been shown to interact with Ewing sarcoma breakpoint region 1 and DVL2....

.ERG
Erg
An erg is the unit of energy and mechanical work in the centimetre-gram-second system of units, symbol "erg". Its name is derived from the Greek ergon, meaning "work"....

, ATF-1,

External links

  • Ewing sarcoma breakpoint region 1 on the Atlas of Genetics and Oncology
    Atlas of Genetics and Cytogenetics in Oncology and Haematology
    The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a collection of resources on genes, chromosomes anomalies, leukemias, solid tumours, and cancer-prone diseases...

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
x
OK