Synthesis

1. BOC
   BOC
   BOC may refer toBanks:* Bank of Canada, Canada's central bank* Bank of China, a major state-owned bank in the People's Republic of China* Bank of Ceylon, a major government-owned commercial bank* Bank of Cyprus, a major cypriot financial institution...
   
    Protecting group
   Protecting group
   A protecting group or protective group is introduced into a molecule by chemical modification of a functional group in order to obtain chemoselectivity in a subsequent chemical reaction...
   
   .
2. Enolization and trapping with triflate
   Triflate
   Trifluoromethanesulfonate, also known by the trivial name triflate, is a functional group with the formula CF3SO3-. The triflate group is often represented by -OTf, as opposed to -Tf...
   
    group.
3. Suzuki reaction
   Suzuki reaction
   The Suzuki reaction is the organic reaction of an aryl- or vinyl-boronic acid with an aryl- or vinyl-halide catalyzed by a palladium complex. It is widely used to synthesize poly-olefins, styrenes, and substituted biphenyls, and has been extended to incorporate alkyl bromides...
   
   
4. Reduction
5. Trifluoroacetic acid
   Trifluoroacetic acid
   Trifluoroacetic acid is the simplest stable perfluorinated carboxylic acid chemical compound, with the formula CF3CO2H. It is a strong carboxylic acid due to the influence of the electronegative trifluoromethyl group. TFA is almost 100,000-fold more acidic than acetic acid...
   
    (TFA) removal of protecting group.
6. Simmons–Smith reaction cyclopropanation.
7. Williamson ether synthesis
   Williamson ether synthesis
   The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and an alcohol. This reaction was developed by Alexander Williamson in 1850. Typically it involves the reaction of an alkoxide ion with a primary alkyl halide via an SN2 reaction...
   
   .