Gabriele Falloppio
Encyclopedia
Gabriele Falloppio often known by his Latin
Latin
Latin is an Italic language originally spoken in Latium and Ancient Rome. It, along with most European languages, is a descendant of the ancient Proto-Indo-European language. Although it is considered a dead language, a number of scholars and members of the Christian clergy speak it fluently, and...

 name Fallopius, was one of the most important anatomists
Human anatomy
Human anatomy is primarily the scientific study of the morphology of the human body. Anatomy is subdivided into gross anatomy and microscopic anatomy. Gross anatomy is the study of anatomical structures that can be seen by the naked eye...

 and physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

s of the sixteenth century.

He was born at Modena
Modena
Modena is a city and comune on the south side of the Po Valley, in the Province of Modena in the Emilia-Romagna region of Italy....

 and died at Padua
Padua
Padua is a city and comune in the Veneto, northern Italy. It is the capital of the province of Padua and the economic and communications hub of the area. Padua's population is 212,500 . The city is sometimes included, with Venice and Treviso, in the Padua-Treviso-Venice Metropolitan Area, having...

. His family was noble but very poor and it was only by a hard struggle he succeeded in obtaining an education. Financial difficulties led him to join the clergy
Clergy
Clergy is the generic term used to describe the formal religious leadership within a given religion. A clergyman, churchman or cleric is a member of the clergy, especially one who is a priest, preacher, pastor, or other religious professional....

, and in 1542, he became a canon
Canon (priest)
A canon is a priest or minister who is a member of certain bodies of the Christian clergy subject to an ecclesiastical rule ....

 at Modena's cathedral
Cathedral
A cathedral is a Christian church that contains the seat of a bishop...

. He studied medicine at the University of Ferrara
University of Ferrara
The University of Ferrara is the main university of the city of Ferrara in the Emilia-Romagna region of northern Italy. In the years prior to the First World War the University of Ferrara, with more than 500 students, was the best attended of the free universities in Italy...

, at that time one of the best medical schools in Europe. He received his MD in 1548 under the guidance of Antonio Musa Brassavola
Antonio Musa Brassavola
Antonio Musa Brassavola was an Italian physician and one of the most famous of his time. He studied under Niccolò Leoniceno and Manardi. He was the friend and physician of Ercolo II, the prince of Este...

. After taking his degree he worked at various medical schools and then became professor of anatomy at Ferrara, in 1548. Girolamo Fabrici was one of his famous students. He was called the next year to the University of Pisa
University of Pisa
The University of Pisa , located in Pisa, Tuscany, is one of the oldest universities in Italy. It was formally founded on September 3, 1343 by an edict of Pope Clement VI, although there had been lectures on law in Pisa since the 11th century...

, then the most important university in Italy. In 1551 Falloppio was invited by Cosimo I, Grand Duke of Tuscany
Cosimo I de' Medici, Grand Duke of Tuscany
Cosimo I de' Medici was Duke of Florence from 1537 to 1574, reigning as the first Grand Duke of Tuscany from 1569.-Biography:...

, to occupy the chair of anatomy and surgery at the University of Padua
University of Padua
The University of Padua is a premier Italian university located in the city of Padua, Italy. The University of Padua was founded in 1222 as a school of law and was one of the most prominent universities in early modern Europe. It is among the earliest universities of the world and the second...

. He also held the professorship of botany
Botany
Botany, plant science, or plant biology is a branch of biology that involves the scientific study of plant life. Traditionally, botany also included the study of fungi, algae and viruses...

 and was superintendent of the botanical gardens. Though he died when less than forty, he had made his mark on anatomy for all time.

This was the golden age of anatomy and Falloppio's contemporaries included such great anatomists as Vesalius
Vesalius
Andreas Vesalius was a Flemish anatomist, physician, and author of one of the most influential books on human anatomy, De humani corporis fabrica . Vesalius is often referred to as the founder of modern human anatomy. Vesalius is the Latinized form of Andries van Wesel...

, Eustachius
Bartolomeo Eustachi
Bartolomeo Eustachi , also known by his Latin name of Eustachius, was one of the founders of the science of human anatomy.-Life:...

, and Realdo Colombo
Realdo Colombo
Realdo Colombo was an Italian professor of anatomy and a surgeon at the University of Padua between 1544 and 1559.- Early life and education :Matteo Realdo Colombo or Renaldus Columbus, was born in Cremona, Lombardy to an apothecary named Antonio Colombo...

 (whom he succeeded at Padua). It has sometimes been asserted that he was jealous of certain of the great discoverers in anatomy and that this is the reason for his frequent criticisms and corrections of their work. However, Heinrich Haeser, an authority in the history of medicine
History of medicine
All human societies have medical beliefs that provide explanations for birth, death, and disease. Throughout history, illness has been attributed to witchcraft, demons, astral influence, or the will of the gods...

, declared that Falloppio was noted for his modesty and deference to his fellow workers and especially to Vesalius. His purpose in suggesting corrections, therefore, was the advance of the science of anatomy.

Falloppio's own work dealt mainly with the anatomy of the head. He added much to what was known before about the internal ear and described in detail the tympanum
Eardrum
The eardrum, or tympanic membrane, is a thin membrane that separates the external ear from the middle ear in humans and other tetrapods. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles...

 and its relations to the osseous ring in which it is situated. He also described minutely the circular
Round window
The round window is one of the two openings into the inner ear. It is closed off from the middle ear by the round window membrane, which vibrates with opposite phase to vibrations entering the inner ear through the oval window...

 and oval window
Oval window
The oval window is a membrane-covered opening which leads from the middle ear to the vestibule of the inner ear.Vibrations that come into contact with the tympanic membrane travel through the three ossicles and into the inner ear...

s (fenestræ) and their communication with the vestibule
Vestibule of the ear
-Definition:The vestibule is the central part of the osseous labyrinth, and is situated medial to the tympanic cavity, behind the cochlea, and in front of the semicircular canals.The etymology comes from the Latin vestibulum, literally an entrance hall....

 and cochlea
Cochlea
The cochlea is the auditory portion of the inner ear. It is a spiral-shaped cavity in the bony labyrinth, making 2.5 turns around its axis, the modiolus....

. He was the first to point out the connection between the mastoid cells
Mastoid cells
A section of the mastoid process of the temporal bone of the cranium shows it to be hollowed out into a number of spaces, the mastoid cells, which exhibit the greatest possible variety as to their size and number....

 and the middle ear
Middle ear
The middle ear is the portion of the ear internal to the eardrum, and external to the oval window of the cochlea. The mammalian middle ear contains three ossicles, which couple vibration of the eardrum into waves in the fluid and membranes of the inner ear. The hollow space of the middle ear has...

. His description of the lacrimal ducts
Lacrimal canaliculi
The lacrimal canaliculi, also known as the lacrimal canals or lacrimal ducts, are the small channels in each eyelid that commence at minute orifices, termed puncta lacrimalia, on the summits of the papillae lacrimales, seen on the margins of the lids at the lateral extremity of the lacus...

 in the eye
Human eye
The human eye is an organ which reacts to light for several purposes. As a conscious sense organ, the eye allows vision. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth...

 was a marked advance on those of his predecessors and he also gave a detailed account of the ethmoid bone
Ethmoid bone
The ethmoid bone is a bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye...

 and its cells in the nose. His contributions to the anatomy of the bone
Bone
Bones are rigid organs that constitute part of the endoskeleton of vertebrates. They support, and protect the various organs of the body, produce red and white blood cells and store minerals. Bone tissue is a type of dense connective tissue...

s and muscle
Muscle
Muscle is a contractile tissue of animals and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They are classified as skeletal, cardiac, or smooth muscles. Their function is to...

s were very valuable. It was in myology
Myology
The muscular system consists of skeletal muscle that act to move or position parts of the body , or smooth and cardiac muscle that propels, expels, or controls the flow of fluids and contained substance.The British Myology Society is an example of a professional group promoting myology ...

 particularly that he corrected Vesalius. He studied the reproductive organs in both sexes, and described the Fallopian tube
Fallopian tube
The Fallopian tubes, also known as oviducts, uterine tubes, and salpinges are two very fine tubes lined with ciliated epithelia, leading from the ovaries of female mammals into the uterus, via the utero-tubal junction...

, which leads from the ovary
Ovary
The ovary is an ovum-producing reproductive organ, often found in pairs as part of the vertebrate female reproductive system. Ovaries in anatomically female individuals are analogous to testes in anatomically male individuals, in that they are both gonads and endocrine glands.-Human anatomy:Ovaries...

 to the uterus
Uterus
The uterus or womb is a major female hormone-responsive reproductive sex organ of most mammals including humans. One end, the cervix, opens into the vagina, while the other is connected to one or both fallopian tubes, depending on the species...

 and now bears his name. The aquæductus Fallopii
Facial canal
The facial canal is a Z-shaped canal running through the temporal bone from the internal acoustic meatus to the stylomastoid foramen. In humans it is approximately 3 centimeters long, which makes it the longest human osseous canal of a nerve...

, the canal through which the facial nerve
Facial nerve
The facial nerve is the seventh of twelve paired cranial nerves. It emerges from the brainstem between the pons and the medulla, and controls the muscles of facial expression, and functions in the conveyance of taste sensations from the anterior two-thirds of the tongue and oral cavity...

 passes after leaving the auditory nerve, is also named after him.

His contributions to practical medicine were also important. He was the first to use an aural speculum
Speculum
The term speculum, Latin for "mirror", and its plural specula, may refer to:* Speculum , a medical tool used for examining body cavities* Speculum , a journal of medieval studies published by the Medieval Academy of America...

 for the diagnosis and treatment of diseases of the ear, and his writings on surgical subjects are still of interest. He published two treatises on ulcer
Peptic ulcer
A peptic ulcer, also known as PUD or peptic ulcer disease, is the most common ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful. It is defined as mucosal erosions equal to or greater than 0.5 cm...

s and tumor
Tumor
A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...

s, a treatise on surgery, and a commentary on Hippocrates
Hippocrates
Hippocrates of Cos or Hippokrates of Kos was an ancient Greek physician of the Age of Pericles , and is considered one of the most outstanding figures in the history of medicine...

's book on wounds of the head. In his own time he was regarded as somewhat of an authority in the field of sexuality. His treatise on syphilis
Syphilis
Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum. The primary route of transmission is through sexual contact; however, it may also be transmitted from mother to fetus during pregnancy or at birth, resulting in congenital syphilis...

 advocated the use of condom
Condom
A condom is a barrier device most commonly used during sexual intercourse to reduce the probability of pregnancy and spreading sexually transmitted diseases . It is put on a man's erect penis and physically blocks ejaculated semen from entering the body of a sexual partner...

s, and he initiated what may have been the first clinical trial
Clinical trial
Clinical trials are a set of procedures in medical research and drug development that are conducted to allow safety and efficacy data to be collected for health interventions...

 of the device. Falloppio was also interested in every form of therapeutics. He wrote a treatise on baths and thermal waters, another on simple purgatives
Laxative
Laxatives are foods, compounds, or drugs taken to induce bowel movements or to loosen the stool, most often taken to treat constipation. Certain stimulant, lubricant, and saline laxatives are used to evacuate the colon for rectal and/or bowel examinations, and may be supplemented by enemas under...

, and a third on the composition of drugs
Medication
A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease.- Classification :...

. None of these works, except his Anatomy (Venice
Venice
Venice is a city in northern Italy which is renowned for the beauty of its setting, its architecture and its artworks. It is the capital of the Veneto region...

, 1561), were published during his lifetime. As we have them, they consist of manuscripts of his lectures and notes of his students. They were published by Volcher Coiter
Volcher Coiter
Volcher Coiter was a Dutch anatomist who established the study of comparative osteology and first described cerebrospinal meningitis.Coiter was born in Groningen...

 (Nuremberg
Nuremberg
Nuremberg[p] is a city in the German state of Bavaria, in the administrative region of Middle Franconia. Situated on the Pegnitz river and the Rhine–Main–Danube Canal, it is located about north of Munich and is Franconia's largest city. The population is 505,664...

, 1575).

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