Gopal Kundu
Encyclopedia
Gopal Kundu is an Indian scientist. He obtained his Ph.D. from Bose Institute
, Kolkata
, India
(1989) in protein
biochemistry
and did his post-doctoral research work at the Cleveland Clinic Foundation, University of Colorado
, University of Wyoming
, and the National Institutes of Health
from 1989 to 1998. He has performed work in the area of cardiovascular biology, inflammation
and immunomodulation during that period. In 1998, he joined as Scientist-D at the National Centre for Cell Science (NCCS), Pune
. At present, he is working as Scientist-F at NCCS. His area of research at NCCS is tumor
biology, regulation of gene expression, cell signaling, angiogenesis
, cancer therapeutics, biomarker studies for cancer detection, and nanomedicine
.
. The allegation was that they had rehashed the same set of data which they had published earlier. An internal committee of the NCCS advised the authors to take back their paper, however an independent committee led by G. Padmanabhan, a former director of Indian Institute of Science, Bangalore, concluded that there was no manipulation in the data. This led to some heated debate between Indian Scientists with several viewpoints being presented. On 23 February 2007, the Journal of Biological Chemistry
withdrew the paper amid allegations of data manipulation, although the authors maintained that the two papers used different set of data though similar experiments.
In November 2010, after an internal investigation by its ethics committee, the Indian Academy of Sciences
banned Gopal Kundu from participating in its activities for three years.
Bose Institute
Bose Institute is a research institute in the fields of Physics, Chemistry, Plant biology, Microbiology, Biochemistry, Biophysics, Animal physiology, Immunotechnology and Environmental science. The institute was established in 1917 by Acharya Jagdish Chandra Bose, who was the founder of modern...
, Kolkata
Kolkata
Kolkata , formerly known as Calcutta, is the capital of the Indian state of West Bengal. Located on the east bank of the Hooghly River, it was the commercial capital of East India...
, India
India
India , officially the Republic of India , is a country in South Asia. It is the seventh-largest country by geographical area, the second-most populous country with over 1.2 billion people, and the most populous democracy in the world...
(1989) in protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
biochemistry
Biochemistry
Biochemistry, sometimes called biological chemistry, is the study of chemical processes in living organisms, including, but not limited to, living matter. Biochemistry governs all living organisms and living processes...
and did his post-doctoral research work at the Cleveland Clinic Foundation, University of Colorado
University of Colorado
The University of Colorado system is a system of public universities in Colorado consisting of three universities in four campuses: University of Colorado Boulder, University of Colorado Colorado Springs, and University of Colorado Denver in downtown Denver and at the Anschutz Medical Campus in...
, University of Wyoming
University of Wyoming
The University of Wyoming is a land-grant university located in Laramie, Wyoming, situated on Wyoming's high Laramie Plains, at an elevation of 7,200 feet , between the Laramie and Snowy Range mountains. It is known as UW to people close to the university...
, and the National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...
from 1989 to 1998. He has performed work in the area of cardiovascular biology, inflammation
Inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...
and immunomodulation during that period. In 1998, he joined as Scientist-D at the National Centre for Cell Science (NCCS), Pune
Pune
Pune , is the eighth largest metropolis in India, the second largest in the state of Maharashtra after Mumbai, and the largest city in the Western Ghats. Once the centre of power of the Maratha Empire, it is situated 560 metres above sea level on the Deccan plateau at the confluence of the Mula ...
. At present, he is working as Scientist-F at NCCS. His area of research at NCCS is tumor
Tumor
A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...
biology, regulation of gene expression, cell signaling, angiogenesis
Angiogenesis
Angiogenesis is the physiological process involving the growth of new blood vessels from pre-existing vessels. Though there has been some debate over terminology, vasculogenesis is the term used for spontaneous blood-vessel formation, and intussusception is the term for the formation of new blood...
, cancer therapeutics, biomarker studies for cancer detection, and nanomedicine
Nanomedicine
Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology. Current problems for nanomedicine involve understanding the issues related...
.
Awards
In 2004 Kundu was awarded a Shanti Swarup Bhatnagar Prize for Science and Technology, following the receipt of an earlier Indian National Bioscience award.Plagiarism controversy
A controversy erupted in the NCCS in 2006 when an anonymous mail alleged that Kundu and others might have misrepresented data in a paper published in the Journal of Biological ChemistryJournal of Biological Chemistry
The Journal of Biological Chemistry is a weekly peer-reviewed scientific journal that was established in 1905. Since 1925 it is published by the American Society for Biochemistry and Molecular Biology. It covers research in any area of biochemistry or molecular biology. The editor-in-chief is...
. The allegation was that they had rehashed the same set of data which they had published earlier. An internal committee of the NCCS advised the authors to take back their paper, however an independent committee led by G. Padmanabhan, a former director of Indian Institute of Science, Bangalore, concluded that there was no manipulation in the data. This led to some heated debate between Indian Scientists with several viewpoints being presented. On 23 February 2007, the Journal of Biological Chemistry
Journal of Biological Chemistry
The Journal of Biological Chemistry is a weekly peer-reviewed scientific journal that was established in 1905. Since 1925 it is published by the American Society for Biochemistry and Molecular Biology. It covers research in any area of biochemistry or molecular biology. The editor-in-chief is...
withdrew the paper amid allegations of data manipulation, although the authors maintained that the two papers used different set of data though similar experiments.
In November 2010, after an internal investigation by its ethics committee, the Indian Academy of Sciences
Indian Academy of Sciences
The Indian Academy of Sciences, Bangalore was founded by Sir C. V. Raman, and was registered as a Society on 24 April 1934. Inaugurated on 31 July 1934, it began with 65 founding fellows. The first general meeting of Fellows, held on the same day, elected Professor Raman as President, and adopted...
banned Gopal Kundu from participating in its activities for three years.
Selected publications
- G C Kundu, G Mantile, L Miele, E Cordella-Miele, and A B Mukherjee (1996) "Recombinant human uteroglobin suppresses cellular invasiveness via a novel class of high-affinity cell surface binding site," PNAS, April 2, Vol. 93 (7), 2915-2919. http://www.pnas.org/content/93/7/2915.full.pdf
- Gopal C. Kundu and Anil B. Mukherjee (1997) "Evidence That Porcine Pancreatic Phospholipase A2 via Its High Affinity Receptor Stimulates Extracellular Matrix Invasion by Normal and Cancer Cells," Journal of Biological ChemistryJournal of Biological ChemistryThe Journal of Biological Chemistry is a weekly peer-reviewed scientific journal that was established in 1905. Since 1925 it is published by the American Society for Biochemistry and Molecular Biology. It covers research in any area of biochemistry or molecular biology. The editor-in-chief is...
, January 24, Vol. 272 (4), 2346-2353. http://www.jbc.org/content/272/4/2346.full.pdf - Gopal C. Kundu, Asim K. Mandal, Zhongjian Zhang, Giuditta Mantile-Selvaggi and Anil B. Mukherjee (1998), "Uteroglobin (UG) Suppresses Extracellular Matrix Invasion by Normal and Cancer Cells That Express the High Affinity UG-binding Proteins," Journal of Biological ChemistryJournal of Biological ChemistryThe Journal of Biological Chemistry is a weekly peer-reviewed scientific journal that was established in 1905. Since 1925 it is published by the American Society for Biochemistry and Molecular Biology. It covers research in any area of biochemistry or molecular biology. The editor-in-chief is...
, August 28, Vol. 273 (35), 22819-22824. http://www.jbc.org/content/273/35/22819.full.pdf