Grundmann aldehyde synthesis
Encyclopedia
The Grundmann aldehyde synthesis is a chemical reaction
that produces an aldehyde
from an acyl halide
.
Because of the Rosenmund reduction
and DIBAL-H accomplish similar transformations, this reaction sequence is not practiced much currently.
Chemical reaction
A chemical reaction is a process that leads to the transformation of one set of chemical substances to another. Chemical reactions can be either spontaneous, requiring no input of energy, or non-spontaneous, typically following the input of some type of energy, such as heat, light or electricity...
that produces an aldehyde
Aldehyde
An aldehyde is an organic compound containing a formyl group. This functional group, with the structure R-CHO, consists of a carbonyl center bonded to hydrogen and an R group....
from an acyl halide
Acyl halide
An acyl halide is a chemical compound derived from an oxoacid by replacing a hydroxyl group with a halide group....
.
Rosenmund reduction
The Rosenmund reduction is a chemical reaction that reduces an acid halide to an aldehyde using hydrogen gas over palladium-on-carbon poisoned with barium sulfate...
and DIBAL-H accomplish similar transformations, this reaction sequence is not practiced much currently.