HLA-A23
Encyclopedia
HLA-A23 is a human leukocyte antigen
serotype
within HLA-A
serotype group. The serotype is determined by the antibody recognition of α23 subset of HLA-A α-chains. For A23, the alpha, "A", chain are encoded by the HLA-A*23 allele group and the β-chain are encoded by B2M
locus. This group currently is dominated by A*2301. A23 and A*23 are almost synonymous in meaning.
A23 is a split antigen of the broad antigen HLA-A9
and it is a sister serotype of HLA-A24
.
A23 is common in Africa and regions of the Middle East, Mediterranean, and India than Europe, East Asia or the Americas.
A23-B44 is found in Albania, Zimbabwe, Morocco, Spain and Danes.
A23-B58 is found in the !kung and Zaire.
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
within HLA-A
HLA-A
HLA-A are a group of human leukocyte antigens that are encoded by the HLA-A locus on human chromosome 6p. The HLA genes constitute a large subset of the Major histocompatibility complex of humans. HLA-A is a component of certain MHC class I cell surface receptor isoforms that resides on the...
serotype group. The serotype is determined by the antibody recognition of α23 subset of HLA-A α-chains. For A23, the alpha, "A", chain are encoded by the HLA-A*23 allele group and the β-chain are encoded by B2M
B2M
B2M may refer to:*Boyz II Men, a singing group*Mitsubishi B2M, an aircraft*Back to Mine, a series of albums*Beta-2 microglobulin, a gene or protein*Business to machine, the practice of E-commerce where companies link directly to machines...
locus. This group currently is dominated by A*2301. A23 and A*23 are almost synonymous in meaning.
A23 is a split antigen of the broad antigen HLA-A9
HLA-A9
HLA-A9 is a broad antigen HLA-A serotype that recognized the HLA-A23 and HLA-A24 serotypes. A*2402 appears to have evolved from A*23 alleles by a process of gene conversion. The A23 is more common in Africa and regions proximal to Africa. A24 is at very high frequencies in Austronesia and certain...
and it is a sister serotype of HLA-A24
HLA-A24
HLA-A24 is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α24 subset of HLA-A α-chains. For A24, the alpha, "A", chain are encoded by the HLA-A*24 allele group and the β-chain are encoded by B2M locus. This group currently...
.
A23 is common in Africa and regions of the Middle East, Mediterranean, and India than Europe, East Asia or the Americas.
Serotype
Allele
Haplotypes
A23-B7 is found in N.Afr. and S.Afr non-caucasians.A23-B44 is found in Albania, Zimbabwe, Morocco, Spain and Danes.
A23-B58 is found in the !kung and Zaire.