HUS1
Encyclopedia
Checkpoint protein HUS1 is a protein
that in humans is encoded by the HUS1 gene
.
with RAD9A
, RAD17
, HDAC1
, RAD1 homolog
and PCNA
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the HUS1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
HUS1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with RAD9A
RAD9A
Cell cycle checkpoint control protein RAD9A is a protein that in humans is encoded by the RAD9A gene.-Interactions:RAD9A has been shown to interact with RAD17, HDAC1, TOPBP1, RAD1 homolog, BCL2-like 1, Bcl-2, Androgen receptor, DNAJC7, HUS1 and Abl gene.-Further reading:...
, RAD17
RAD17
Cell cycle checkpoint protein RAD17 is a protein that in humans is encoded by the RAD17 gene.-Interactions:RAD17 has been shown to interact with RAD9A, RAD1 homolog, POLE, NHP2L1, Ataxia telangiectasia mutated, HUS1 and Ataxia telangiectasia and Rad3 related.-Further reading:...
, HDAC1
HDAC1
Histone deacetylase 1 is an enzyme that in humans is encoded by the HDAC1 gene.-Interactions:HDAC1 has been shown to interact with RAD9A, DNMT3L, MTA1, FKBP3, CDC20, CDH1, Host cell factor C1, BUB3, Nuclear receptor co-repressor 2, IKZF1, Prohibitin, EVI1, DDX5, DNMT3A, Mothers against...
, RAD1 homolog
RAD1 homolog
Cell cycle checkpoint protein RAD1 is a protein that in humans is encoded by the RAD1 gene.-Interactions:RAD1 homolog has been shown to interact with RAD9A, RAD17 and HUS1.-Further reading:...
and PCNA
PCNA
Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. It achieves this processivity by encircling the DNA, thus creating a topological link to the genome...
.