Ioan Puscas
Encyclopedia
Ioan Puşcaş is a gastroenterologist
, born in Treznea
, Sălaj
, Romania
. In the 1970s, he proposed the use of carbonic anhydrase
(CA) inhibitor acetazolamide
to heal peptic ulcer
s.Treatment of Gastroduodenal Ulcers with Carbonic Anhydrase Inhibitors, Annals of the New York Academy of Sciences, Volume 429 (June 1984)
Gastroenterology
Gastroenterology is the branch of medicine whereby the digestive system and its disorders are studied. The name is a combination of three Ancient Greek words gaster , enteron , and logos...
, born in Treznea
Treznea
Treznea is a commune in Sălaj County, Romania. It is composed of two villages, Bozna and Treznea. These were part of Agrij Commune until 1995, when they were split off to form a separate commune....
, Sălaj
Salaj County
Sălaj is a county of Romania, in the historical regions of Crișana and Transylvania, with the capital city at Zalău.-Geography:Sălaj county has a total area of ....
, Romania
Romania
Romania is a country located at the crossroads of Central and Southeastern Europe, on the Lower Danube, within and outside the Carpathian arch, bordering on the Black Sea...
. In the 1970s, he proposed the use of carbonic anhydrase
Carbonic anhydrase
The carbonic anhydrases form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons , a reversible reaction that occurs rather slowly in the absence of a catalyst...
(CA) inhibitor acetazolamide
Acetazolamide
Acetazolamide, sold under the trade name Diamox, is a carbonic anhydrase inhibitor that is used to treat glaucoma, epileptic seizures, Idiopathic intracranial hypertension , altitude sickness, cystinuria, and dural ectasia...
to heal peptic ulcer
Peptic ulcer
A peptic ulcer, also known as PUD or peptic ulcer disease, is the most common ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful. It is defined as mucosal erosions equal to or greater than 0.5 cm...
s.Treatment of Gastroduodenal Ulcers with Carbonic Anhydrase Inhibitors, Annals of the New York Academy of Sciences, Volume 429 (June 1984)