Iodixanol
Encyclopedia
Iodixanol is a contrast agent, sold under the trade name Visipaque. Visipaque is commonly used as a contrast agent
during coronary angiography. It is the only iso-osmolar contrast agent, with an osmolality of 290 mOsm/kg H2O, the same as blood. It is sold in 2 main concentrations 270 mgI/ml and 320 mgI/ml - hence the name Visipaque 270 or 320. It is sold in single dose units and a large 500ml plastic bottle for multi-dose dispensing
It was originally made by Nycomed, which then merged with Amersham which finally was bought by Jeff Immelt to become GE Healthcare. The majority of Visipaque is made in Cork, Ireland, with additional plants in China and Oslo. All Iodixanol bulk powder is made in Norway and shipped to the various plants for final manufacture.
For density gradient centrifugation
, the product is known as OptiPrep.
A very similar product also manufactured by GE Healthcare is Omnipaque (Iohexol
as the main drug substance).
Radiocontrast
Radiocontrast agents are a type of medical contrast medium used to improve the visibility of internal bodily structures in an X-ray based imaging techniques such as computed tomography or radiography...
during coronary angiography. It is the only iso-osmolar contrast agent, with an osmolality of 290 mOsm/kg H2O, the same as blood. It is sold in 2 main concentrations 270 mgI/ml and 320 mgI/ml - hence the name Visipaque 270 or 320. It is sold in single dose units and a large 500ml plastic bottle for multi-dose dispensing
It was originally made by Nycomed, which then merged with Amersham which finally was bought by Jeff Immelt to become GE Healthcare. The majority of Visipaque is made in Cork, Ireland, with additional plants in China and Oslo. All Iodixanol bulk powder is made in Norway and shipped to the various plants for final manufacture.
For density gradient centrifugation
Differential centrifugation
Differential centrifugation is a common procedure in microbiology and cytology used to separate certain organelles from whole cells for further analysis of specific parts of cells. In the process, a tissue sample is first homogenised to break the cell membranes and mix up the cell contents...
, the product is known as OptiPrep.
A very similar product also manufactured by GE Healthcare is Omnipaque (Iohexol
Iohexol
Iohexol is a contrast agent, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter...
as the main drug substance).
External links
- http://www.amershamhealth-us.com/visipaque/
- http://www.amershamhealth-us.com/visipaque/
- http://www.gehealthcare.com/caen/md/docs/visipaquepieng.pdf