Iohexol
Encyclopedia
Iohexol is a contrast agent
, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine
per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.
The osmolality of iohexol ranges from 322 mOsm
/kg—approximately 1.1 times that of blood plasma
—to 844 mOsm/kg, almost three times that of blood. Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate
, may be more than twice as high.
Radiocontrast
Radiocontrast agents are a type of medical contrast medium used to improve the visibility of internal bodily structures in an X-ray based imaging techniques such as computed tomography or radiography...
, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine
Iodine
Iodine is a chemical element with the symbol I and atomic number 53. The name is pronounced , , or . The name is from the , meaning violet or purple, due to the color of elemental iodine vapor....
per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.
The osmolality of iohexol ranges from 322 mOsm
Osmole (unit)
Osmolarity is the measure of solute concentration, defined as the number of osmoles of solute per litre of solution . The osmolarity of a solution is usually expressed as Osm/L , in the same way that the molarity of a solution is expressed as "M"...
/kg—approximately 1.1 times that of blood plasma
Blood plasma
Blood plasma is the straw-colored liquid component of blood in which the blood cells in whole blood are normally suspended. It makes up about 55% of the total blood volume. It is the intravascular fluid part of extracellular fluid...
—to 844 mOsm/kg, almost three times that of blood. Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate
Diatrizoic acid
Diatrizoic acid , also known as amidotrizoic acid, or 3,5-diacetamido-2,4,6-triiodobenzoic acid, is a radiocontrast agent containing iodine. Trade names include Hypaque, Gastrografin and Urografin, the latter being a combination of the sodium and meglumine salts.Diatrizoate is considered a...
, may be more than twice as high.