JWH-147
Encyclopedia
JWH-147 is an analgesic
drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors
. It is somewhat selective for the CB2 subtype, with a Ki
of 11.0nM at CB1 vs 7.1nM at CB2. It was discovered and named after Dr. John W. Huffman
. JWH-147 was banned in Sweden on 1st October 2010 as a hazardous good harmful to health, after being identified as an ingredient in "herbal" synthetic cannabis products.
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....
drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors
Receptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...
. It is somewhat selective for the CB2 subtype, with a Ki
Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant is a specific type of equilibrium constant that measures the propensity of a larger object to separate reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into...
of 11.0nM at CB1 vs 7.1nM at CB2. It was discovered and named after Dr. John W. Huffman
John W. Huffman
John William Huffman is a professor emeritus of organic chemistry at Clemson University who first synthesised many novel cannabinoids, including JWH-007, JWH-015, JWH-018, JWH-019, JWH-030, JWH-051, JWH-073, JWH-081, JWH-122, JWH-133, JWH-147, JWH-171, JWH-182, JWH-203, JWH-210, JWH-250, JWH-307,...
. JWH-147 was banned in Sweden on 1st October 2010 as a hazardous good harmful to health, after being identified as an ingredient in "herbal" synthetic cannabis products.