John Benjamin Murphy
Encyclopedia
John Benjamin Murphy, born John Murphy (December 21, 1857 in Appleton, Wisconsin
Appleton, Wisconsin
Appleton is a city in Outagamie, Calumet, and Winnebago Counties in the U.S. state of Wisconsin. It is situated on the Fox River, 30 miles southwest of Green Bay and 100 miles north of Milwaukee. Appleton is the county seat of Outagamie County. The population was 78,086 at the 2010 census...

 – August 11, 1916 Mackinac Island, Michigan
Mackinac Island, Michigan
Mackinac Island is a city in Mackinac County in the U.S. state of Michigan. In the 2010 census, the city had a permanent population of 492, although there are thousands more seasonal workers and tourists during the summer months. From 1818–1882, the city was the county seat of the former...

), was an American physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

 and abdominal surgeon
Surgeon
In medicine, a surgeon is a specialist in surgery. Surgery is a broad category of invasive medical treatment that involves the cutting of a body, whether human or animal, for a specific reason such as the removal of diseased tissue or to repair a tear or breakage...

 noted for advocating early surgical intervention in appendicitis appendectomy, and several eponym
Eponym
An eponym is the name of a person or thing, whether real or fictitious, after which a particular place, tribe, era, discovery, or other item is named or thought to be named...

s: Murphy’s button, Murphy drip
Murphy drip
A Murphy drip is a rectal infusion apparatus to administer the medical procedure of proctoclysis, also known as rectoclysis. During the procedure, an end of the Murphy drip is inserted into the rectum and large quantities of liquid are infused into the rectum drop-by-drop...

, Murphy’s punch
Murphy's punch sign
Kidney punch or CVA Tenderness is elicited when gently tapping the area of the back overlying the kidneyproducing pain in people with an infection around the kidney or pyelonephritis or renal stone...

, Murphy’s test, and Murphy-Lane bone skid. He is best remembered for the eponymous clinical sign that is used in evaluating patients with acute cholecystitis
Cholecystitis
-Signs and symptoms:Cholecystitis usually presents as a pain in the right upper quadrant. This is known as biliary colic. This is initially intermittent, but later usually presents as a constant, severe pain. During the initial stages, the pain may be felt in an area totally separate from the site...

. His career spanned general surgery, orthopedics
Orthopedics
Orthopedics is the study of the musculoskeletal system. The Greek word 'ortho' means straight or correct and 'pedics' comes from the Greek 'pais' meaning children. For many centuries, orthopedists have been involved in the treatment of crippled children...

, neurosurgery
Neurosurgery
Neurosurgery is the medical specialty concerned with the prevention, diagnosis, treatment, and rehabilitation of disorders which affect any portion of the nervous system including the brain, spine, spinal cord, peripheral nerves, and extra-cranial cerebrovascular system.-In the United States:In...

, and cardiothoracic surgery
Cardiothoracic Surgery
Cardiothoracic surgery is the field of medicine involved in surgical treatment of diseases affecting organs inside the thorax —generally treatment of conditions of the heart and lungs .-Cardiac / Thoracic:...

, which helped him to gain international prominence in the surgical profession. Mayo Clinic
Mayo Clinic
Mayo Clinic is a not-for-profit medical practice and medical research group specializing in treating difficult patients . Patients are referred to Mayo Clinic from across the U.S. and the world, and it is known for innovative and effective treatments. Mayo Clinic is known for being at the top of...

 co-founder William James Mayo
William James Mayo
William James Mayo, M.D. was a physician in the United States and one of the seven founders of the Mayo Clinic. He and his brother, Charles Horace Mayo, both joined their father's private medical practice in Rochester, Minnesota, USA, after graduating from medical school in the 1880s...

 called him "the surgical genius of our generation".

Over the course of his career he was renowned as a surgeon, a clinician, a teacher, an innovator, and an author. In addition to general surgical operations, such as appendectomy, cholecystostomy, bowel resection for intestinal obstruction, and mastectomy
Mastectomy
Mastectomy is the medical term for the surgical removal of one or both breasts, partially or completely. Mastectomy is usually done to treat breast cancer; in some cases, women and some men believed to be at high risk of breast cancer have the operation prophylactically, that is, to prevent cancer...

, he performed and described innovative procedures in neurosurgery
Neurosurgery
Neurosurgery is the medical specialty concerned with the prevention, diagnosis, treatment, and rehabilitation of disorders which affect any portion of the nervous system including the brain, spine, spinal cord, peripheral nerves, and extra-cranial cerebrovascular system.-In the United States:In...

, orthopedics
Orthopedics
Orthopedics is the study of the musculoskeletal system. The Greek word 'ortho' means straight or correct and 'pedics' comes from the Greek 'pais' meaning children. For many centuries, orthopedists have been involved in the treatment of crippled children...

, gynecology, urology
Urology
Urology is the medical and surgical specialty that focuses on the urinary tracts of males and females, and on the reproductive system of males. Medical professionals specializing in the field of urology are called urologists and are trained to diagnose, treat, and manage patients with urological...

, plastic surgery
Plastic surgery
Plastic surgery is a medical specialty concerned with the correction or restoration of form and function. Though cosmetic or aesthetic surgery is the best-known kind of plastic surgery, most plastic surgery is not cosmetic: plastic surgery includes many types of reconstructive surgery, hand...

, thoracic surgery
Thoracic surgery
Thoracic surgery is the field of medicine involved in the surgical treatment of diseases affecting organs inside the thorax . Generally treatment of conditions of the lungs, chest wall, and diaphragm....

, and vascular surgery
Vascular surgery
Vascular surgery is a specialty of surgery in which diseases of the vascular system, or arteries and veins, are managed by medical therapy, minimally-invasive catheter procedures, and surgical reconstruction. The specialty evolved from general and cardiac surgery...

. He also ventured into techniques such as neurorrhaphy, arthroplasty
Arthroplasty
Arthroplasty is an operative procedure of orthopedic surgery performed, in which the arthritic or dysfunctional joint surface is replaced with something better or by remodeling or realigning the joint by osteotomy or some other procedure.-Background:Previously, a popular form of arthroplasty was...

, prostatectomy
Prostatectomy
A prostatectomy is the surgical removal of all or part of the prostate gland. Abnormalities of the prostate, such as a tumour, or if the gland itself becomes enlarged for any reason, can restrict the normal flow of urine along the urethra....

, nephrectomy
Nephrectomy
Nephrectomy is the surgical removal of a kidney.-History:The first successful nephrectomy was performed by the German surgeon Gustav Simon on August 2, 1869 in Heidelberg. Simon practiced the operation beforehand in animal experiments...

, hysterectomy
Hysterectomy
A hysterectomy is the surgical removal of the uterus, usually performed by a gynecologist. Hysterectomy may be total or partial...

, bone grafting
Bone grafting
Bone grafting is a surgical procedure that replaces missing bone in order to repair bone fractures that are extremely complex, pose a significant health risk to the patient, or fail to heal properly....

, and thoracoplasty.

Life and death

Murphy was born in a log cabin
Log cabin
A log cabin is a house built from logs. It is a fairly simple type of log house. A distinction should be drawn between the traditional meanings of "log cabin" and "log house." Historically most "Log cabins" were a simple one- or 1½-story structures, somewhat impermanent, and less finished or less...

 in Appleton, Wisconsin
Appleton, Wisconsin
Appleton is a city in Outagamie, Calumet, and Winnebago Counties in the U.S. state of Wisconsin. It is situated on the Fox River, 30 miles southwest of Green Bay and 100 miles north of Milwaukee. Appleton is the county seat of Outagamie County. The population was 78,086 at the 2010 census...

. His parents, Michael Murphy and Ann Grimes Murphy, were Irish
Irish people
The Irish people are an ethnic group who originate in Ireland, an island in northwestern Europe. Ireland has been populated for around 9,000 years , with the Irish people's earliest ancestors recorded having legends of being descended from groups such as the Nemedians, Fomorians, Fir Bolg, Tuatha...

 immigrants who escaped from the potato famine and who later raised him on their own farm.

Murphy died of heart disease
Heart disease
Heart disease, cardiac disease or cardiopathy is an umbrella term for a variety of diseases affecting the heart. , it is the leading cause of death in the United States, England, Canada and Wales, accounting for 25.4% of the total deaths in the United States.-Types:-Coronary heart disease:Coronary...

 in Mackinac Island, Michigan
Mackinac Island, Michigan
Mackinac Island is a city in Mackinac County in the U.S. state of Michigan. In the 2010 census, the city had a permanent population of 492, although there are thousands more seasonal workers and tourists during the summer months. From 1818–1882, the city was the county seat of the former...

 after having been ill for six months. He was staying at the Grand Hotel
Grand Hotel (Mackinac Island)
The Grand Hotel is a historic hotel and coastal resort located on Mackinac Island, Michigan, a small island located at the eastern end of the Straits of Mackinac within Lake Huron between the state's Upper and Lower Peninsulas. Constructed in the late 19th century, the facility advertises itself as...

 and was attended by his wife and Drs. L. L. MacArthur and James Keefe. After he suffered from angina pectoris for several years, his death was attributed to aortitis
Aortitis
-Causes:This inflammation has a number of possible causes, to include: trauma, viral infection, certain immune disorders, and bacterial infection .-Treatment:...

. Two days prior to his death he correctly predicted the findings of his own autopsy
Autopsy
An autopsy—also known as a post-mortem examination, necropsy , autopsia cadaverum, or obduction—is a highly specialized surgical procedure that consists of a thorough examination of a corpse to determine the cause and manner of death and to evaluate any disease or injury that may be present...

: "I think the necropsy will show plaques in my aorta
Aorta
The aorta is the largest artery in the body, originating from the left ventricle of the heart and extending down to the abdomen, where it branches off into two smaller arteries...

."

Education and training

Murphy attended public school in Appleton and graduated from Appleton High School
Appleton Area School District
The Appleton Area School District is a school district that serves Appleton, Wisconsin. Situated in the heart of the Fox River Valley of northeast Wisconsin, the AASD serves the city of Appleton, Wisconsin and its nearly 80,000 residents...

 in 1876. He obtained a doctorate
Doctorate
A doctorate is an academic degree or professional degree that in most countries refers to a class of degrees which qualify the holder to teach in a specific field, A doctorate is an academic degree or professional degree that in most countries refers to a class of degrees which qualify the holder...

 from Rush Medical College in 1879 and entered an eighteen-month internship at Cook County Hospital. He then practiced there briefly. From 1882–1884 he performed practical work at universities and hospitals in Vienna
Vienna
Vienna is the capital and largest city of the Republic of Austria and one of the nine states of Austria. Vienna is Austria's primary city, with a population of about 1.723 million , and is by far the largest city in Austria, as well as its cultural, economic, and political centre...

, Munich
Munich
Munich The city's motto is "" . Before 2006, it was "Weltstadt mit Herz" . Its native name, , is derived from the Old High German Munichen, meaning "by the monks' place". The city's name derives from the monks of the Benedictine order who founded the city; hence the monk depicted on the city's coat...

, Berlin and Heidelberg
Heidelberg
-Early history:Between 600,000 and 200,000 years ago, "Heidelberg Man" died at nearby Mauer. His jaw bone was discovered in 1907; with scientific dating, his remains were determined to be the earliest evidence of human life in Europe. In the 5th century BC, a Celtic fortress of refuge and place of...

. Most of this time was spent working in Vienna with Theodor Billroth
Theodor Billroth
Christian Albert Theodor Billroth was a German-born Austrian surgeon and amateur musician....

, who introduced gastrectomy
Gastrectomy
A gastrectomy is a partial or full surgical removal of the stomach.-Indications:Gastrectomies are performed to treat cancer and perforations of the stomach wall....

 techniques that are still in use today.

Academic career

After his sojourn in Europe
Europe
Europe is, by convention, one of the world's seven continents. Comprising the westernmost peninsula of Eurasia, Europe is generally 'divided' from Asia to its east by the watershed divides of the Ural and Caucasus Mountains, the Ural River, the Caspian and Black Seas, and the waterways connecting...

, he returned to Chicago to start a general practice. He was quickly recognized as a leader in abdominal surgery and was appointed lecturer in surgery at Rush Medical College
Rush Medical College
Rush Medical College is the medical school of Rush University, a private university in Chicago, Illinois. Rush Medical College was one of the first medical colleges in the state of Illinois and was chartered in 1837, two days before the city of Chicago was chartered, and opened with 22 students on...

 at the end of 1884. In 1890 he was elected Professor of Surgery. In 1892, he was named Professor of Clinical Surgery at the College of Physicians and Surgeons
University of Illinois College of Medicine
The University of Illinois College of Medicine offers a four-year program leading to the MD degree at four different sites in Illinois: Chicago, Peoria, Rockford, and Urbana–Champaign....

 (currently University of Illinois College of Medicine). By 1899, he had become acclaimed for bone surgery. From 1901–1905 he held a position at the Northwestern University Medical School. From 1905–1908, he worked at Rush Medical College, and from 1908–1916 he returned to Northwestern University Medical School. Meanwhile, he also taught at the Graduate Medical School of Chicago, and from 1895 until his death in 1916, he was the surgeon-in-chief at the Mercy Hospital. From 1908 on he also held a commission in the Army Reserve Medical Corps.

While at Mercy, he developed a following for his "wet clinics", in which he operated and lectured to an audience. Physicians from around the world attended these sessions. The only method for wider dissemination of these lectures and demonstrations was print publication. A secretary transcribed his words, and they were printed as "The Surgical Clinics of John B. Murphy, M.D., at Mercy Hospital, Chicago". This became 'The Surgical Clinics of Chicago", and, subsequently, the "Surgical Clinics of North America", which continue in publication in 2008.

Notable experiences

Early in his career, on May 4, 1886, he was one of the doctors summoned to the scene of the Haymarket Affair
Haymarket affair
The Haymarket affair was a demonstration and unrest that took place on Tuesday May 4, 1886, at the Haymarket Square in Chicago. It began as a rally in support of striking workers. An unknown person threw a dynamite bomb at police as they dispersed the public meeting...

 in the Near West Side
Near West Side, Chicago
The Near West Side, one of the 77 defined community areas of Chicago, is located , adjacent to the downtown central business district . The rich history of the Near West Side of Chicago has its genesis in the Hull House phenomenon...

 community area
Community areas of Chicago
Community areas in Chicago refers to the work of the Social Science Research Committee at University of Chicago which has unofficially divided the City of Chicago into 77 community areas. These areas are well-defined and static...

 of Chicago. He dressed approximately 30 men while working until 3:30 AM. A bomb had been thrown at the Chicago Police officers leading to several deaths and a high profile trial, in which Murphy was called to testify. The labor unrest leading up to and surrounding the events led to the tradition of May Day
May Day
May Day on May 1 is an ancient northern hemisphere spring festival and usually a public holiday; it is also a traditional spring holiday in many cultures....

 labor rallies.

After an October 14, 1912 assassination attempt on former United States President Theodore Roosevelt
Theodore Roosevelt
Theodore "Teddy" Roosevelt was the 26th President of the United States . He is noted for his exuberant personality, range of interests and achievements, and his leadership of the Progressive Movement, as well as his "cowboy" persona and robust masculinity...

 in Milwaukee, Wisconsin
Milwaukee, Wisconsin
Milwaukee is the largest city in the U.S. state of Wisconsin, the 28th most populous city in the United States and 39th most populous region in the United States. It is the county seat of Milwaukee County and is located on the southwestern shore of Lake Michigan. According to 2010 census data, the...

, Roosevelt was brought to Chicago's Mercy Hospital. When he asked Roosevelt about any fears he might have about his bullet wound he said that Roosevelt responded, "I've hunted long enough, Doctor, to know that you can't kill a Bull Moose with a short gun."

Legacy

Although his surgical prowess was not questioned, his approach to practice was considered pretentious by a segment of his professional colleagues in the U.S., and his work was more highly regarded by his contemporaries in Europe than in Chicago. He was an early advocate of intervention via the removal of the appendix
Vermiform appendix
The appendix is a blind-ended tube connected to the cecum , from which it develops embryologically. The cecum is a pouchlike structure of the colon...

 in all cases of appendicitis
Appendicitis
Appendicitis is a condition characterized by inflammation of the appendix. It is classified as a medical emergency and many cases require removal of the inflamed appendix, either by laparotomy or laparoscopy. Untreated, mortality is high, mainly because of the risk of rupture leading to...

. His thoughts were controversial in a time of conservative management of appendicitis. Having been met with skepticism after his first presentation of appendectomy, he gathered evidence from 250 cases and presented his opinions again as an authority on the subject.

He was known for the following eponym
Eponym
An eponym is the name of a person or thing, whether real or fictitious, after which a particular place, tribe, era, discovery, or other item is named or thought to be named...

s: Murphy’s button (a mechanical device used for intestinal anastomosis
Surgical anastomosis
In surgical jargon, to create an anastomosis is to join together two hollow organs , usually to restore continuity after resection, or to bypass an unresectable disease process. Historically such procedures were performed with suture material, but increasingly mechanical staplers and biological...

), Murphy’s punch
Murphy's punch sign
Kidney punch or CVA Tenderness is elicited when gently tapping the area of the back overlying the kidneyproducing pain in people with an infection around the kidney or pyelonephritis or renal stone...

 (a punch tenderness at the costo-vertebral angle in cases of perinephric abscess
Abscess
An abscess is a collection of pus that has accumulated in a cavity formed by the tissue in which the pus resides due to an infectious process or other foreign materials...

), Murphy's sign
Murphy's sign
In medicine, Murphy's sign refers to a maneuver during a physical examination as part of the abdominal examination and a finding elicited in ultrasonography. It is useful for differentiating pain in the right upper quadrant...

 (a sign of inflammation of the gallbladder
Gallbladder
In vertebrates the gallbladder is a small organ that aids mainly in fat digestion and concentrates bile produced by the liver. In humans the loss of the gallbladder is usually easily tolerated....

), Murphy’s test (a test for deep-seated tenderness and muscular rigidity in cases of perinephric abscess), Murphy drip
Murphy drip
A Murphy drip is a rectal infusion apparatus to administer the medical procedure of proctoclysis, also known as rectoclysis. During the procedure, an end of the Murphy drip is inserted into the rectum and large quantities of liquid are infused into the rectum drop-by-drop...

 for administration of fluids by proctoclysis in patients with peritonitis
Peritonitis
Peritonitis is an inflammation of the peritoneum, the serous membrane that lines part of the abdominal cavity and viscera. Peritonitis may be localised or generalised, and may result from infection or from a non-infectious process.-Abdominal pain and tenderness:The main manifestations of...

, and Murphy-Lane bone skid (a common commercial steel instrument used for femoral head procedures).

Murphy developed his eponymous anastomotic button for a sutureless anastomosis of the gallbladder
Gallbladder
In vertebrates the gallbladder is a small organ that aids mainly in fat digestion and concentrates bile produced by the liver. In humans the loss of the gallbladder is usually easily tolerated....

 to the duodenum
Duodenum
The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms anterior intestine or proximal intestine may be used instead of duodenum...

 (his preferred treatment for acute cholecystitis
Cholecystitis
-Signs and symptoms:Cholecystitis usually presents as a pain in the right upper quadrant. This is known as biliary colic. This is initially intermittent, but later usually presents as a constant, severe pain. During the initial stages, the pain may be felt in an area totally separate from the site...

), but it was equally suitable for intestinal anastomoses. He developed it in the experimental animal laboratory in a barn behind his house and first used it less than a week after developing it on a dog. The Murphy button can be credited as the forerunner of the modern end-to-end stapling instrument after having become the method of choice for operations at the Mayo Clinic and elsewhere in the United States for over twenty years.

In 1896, Murphy was the first person to successfully unite a femoral artery
Femoral artery
The femoral artery is a general term comprising a few large arteries in the thigh. They begin at the inguinal ligament and end just above the knee at adductor canal or Hunter's canal traversing the extent of the femur bone....

 severed by a gunshot wound. In 1898, Murphy was first in the United States to induce artificial immobilization and collapse of the lung
Pneumothorax
Pneumothorax is a collection of air or gas in the pleural cavity of the chest between the lung and the chest wall. It may occur spontaneously in people without chronic lung conditions as well as in those with lung disease , and many pneumothoraces occur after physical trauma to the chest, blast...

 (pneumothorax) in treatment of pulmonary tuberculosis. He pioneered bone grafting techniques and made inroads in the management of ankylosis
Ankylosis
Ankylosis or anchylosis is a stiffness of a joint due to abnormal adhesion and rigidity of the bones of the joint, which may be the result of injury or disease. The rigidity may be complete or partial and may be due to inflammation of the tendinous or muscular structures outside the joint or of...

, especially with reconstruction
Reconstructive surgery
Reconstructive surgery is, in its broadest sense, the use of surgery to restore the form and function of the body, although Maxillo-Facial Surgeons, Plastic Surgeons and Otolaryngologists do reconstructive surgery on faces after trauma and to reconstruct the head and neck after cancer.Other...

. He was also considered an innovator for surgical intervention for prostate cancer
Prostate cancer
Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostate cancers. The cancer cells may metastasize from the prostate to other parts of the body, particularly...

, performance of end-to-end anastomosis
Anastomosis
An anastomosis is the reconnection of two streams that previously branched out, such as blood vessels or leaf veins. The term is used in medicine, biology, mycology and geology....

 of hollow viscera.

In 1912, he performed what was arguably the first bilary tract endoscopy
Endoscopy
Endoscopy means looking inside and typically refers to looking inside the body for medical reasons using an endoscope , an instrument used to examine the interior of a hollow organ or cavity of the body. Unlike most other medical imaging devices, endoscopes are inserted directly into the organ...

.

He was a founding member of the American College of Surgeons.

Honors

He was knighted with the Order of St. Gregory the Great
Order of St. Gregory the Great
The Pontifical Equestrian Order of St. Gregory the Great , was established on September 1, 1831, by Pope Gregory XVI, seven months after his election.It is one of the five orders of knighthood of the Holy See...

 at the direction of Pope Benedict XV
Pope Benedict XV
Pope Benedict XV , born Giacomo Paolo Giovanni Battista della Chiesa, reigned as Pope from 3 September 1914 to 22 January 1922...

 by Archbishop George Mundelein on June 16, 1916. He was awarded Laetare Medal
Laetare Medal
The Laetare Medal is an annual award given by the University of Notre Dame in recognition of outstanding service to the Roman Catholic church and society...

 by the University of Notre Dame
University of Notre Dame
The University of Notre Dame du Lac is a Catholic research university located in Notre Dame, an unincorporated community north of the city of South Bend, in St. Joseph County, Indiana, United States...

 in 1902, and a Doctor of Science
Doctor of Science
Doctor of Science , usually abbreviated Sc.D., D.Sc., S.D. or Dr.Sc., is an academic research degree awarded in a number of countries throughout the world. In some countries Doctor of Science is the name used for the standard doctorate in the sciences, elsewhere the Sc.D...

 by University of Sheffield
University of Sheffield
The University of Sheffield is a research university based in the city of Sheffield in South Yorkshire, England. It is one of the original 'red brick' universities and is a member of the Russell Group of leading research intensive universities...

, England in 1908.

Although Murphy's flamboyant demeanour and consequent unpopularity among his colleagues kept him from early membership in several professional associations, he was eventually elected President of both the Chicago Medical Society and the American Medical Association (AMA).The American Surgical Association realized their mistake and belatedly granted Murphy membership.

There is a public elementary school named in his honor the John B. Murphy Public School located at 3539 West Grace Street in the Irving Park
Irving Park, Chicago
Irving Park is one of 77 officially designated Chicago community area located on the Northwest Side. It is bounded by the Chicago River on the east, the Milwaukee Road railroad tracks on the west, Addison Street on the south and Montrose Avenue on the north, west of Pulaski Road stretching to...

 community area
Community areas of Chicago
Community areas in Chicago refers to the work of the Social Science Research Committee at University of Chicago which has unofficially divided the City of Chicago into 77 community areas. These areas are well-defined and static...

on the northwest side of Chicago, which opened in 1924.
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