Jpx (gene)
Encyclopedia
In molecular biology, JPX transcript, XIST activator (non-protein coding), also known as Jpx, is a long non-coding RNA. In humans, it is located on the X chromosome
. It was identified during sequence
analysis of the X inactivation centre, surrounding the Xist gene
. Jpx upregulates expression of Xist.
X chromosome
The X chromosome is one of the two sex-determining chromosomes in many animal species, including mammals and is common in both males and females. It is a part of the XY sex-determination system and X0 sex-determination system...
. It was identified during sequence
DNA sequence
The sequence or primary structure of a nucleic acid is the composition of atoms that make up the nucleic acid and the chemical bonds that bond those atoms. Because nucleic acids, such as DNA and RNA, are unbranched polymers, this specification is equivalent to specifying the sequence of...
analysis of the X inactivation centre, surrounding the Xist gene
XIST (gene)
Xist is an RNA gene on the X chromosome of the placental mammals that acts as major effector of the X inactivation process. It is a component of the Xic - X-chromosome inactivation centre - along with two other RNA genes and two protein genes...
. Jpx upregulates expression of Xist.