KPNB1
Encyclopedia
Importin subunit beta-1 is a protein
that in humans is encoded by the KPNB1 gene
.
with NUP98
, Karyopherin alpha 1, KPNA3
, Karyopherin alpha 2, SMN1
, Parathyroid hormone-related protein
, Nucleoporin 62
, RANBP2
, Ran (biology)
, RANBP1
, NUP50
, P53
, NUP153
and Mothers against decapentaplegic homolog 3
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the KPNB1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
KPNB1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with NUP98
NUP98
Nuclear pore complex protein Nup98-Nup96 is a protein that in humans is encoded by the NUP98 gene.-Interactions:NUP98 has been shown to interact with NUP88, KPNB1, RAE1, CREB-binding protein and TNPO2.-Further reading:...
, Karyopherin alpha 1, KPNA3
KPNA3
Importin subunit alpha-3 is a protein that in humans is encoded by the KPNA3 gene.-Further reading:...
, Karyopherin alpha 2, SMN1
SMN1
Survival motor neuron protein is a protein that in humans is encoded by the SMN1 gene.-Interactions:SMN1 has been shown to interact with Gem-associated protein 7, GEMIN4, KPNB1, Survival of motor neuron protein-interacting protein 1, DDX20, Coilin, Small nuclear ribonucleoprotein D1, Fibrillarin,...
, Parathyroid hormone-related protein
Parathyroid hormone-related protein
Parathyroid hormone-related protein is a protein member of the parathyroid hormone family. It is occasionally secreted by cancer cells . However, it also has normal functions.- Function :PTHrP acts as an endocrine, autocrine, paracrine, and intracrine hormone...
, Nucleoporin 62
Nucleoporin 62
Nucleoporin p62 is a protein complex associated with the nuclear envelope. The p62 protein remains associated with the nuclear pore complex-lamina fraction. p62 is synthesized as a soluble cytoplasmic precursor of 61 kDa followed by modification that involve addition of N-acetylglucosamine residues...
, RANBP2
RANBP2
RAN binding protein 2, also known as RANBP2 is protein which in humans is encoded by the RANBP2 gene.RanBP2 is also known as Nup358 since it is a member nucleoporin family that makes-up the nuclear pore complex. RanBP2 has a 358 KDa molecular weight.- Function :RAN is a small GTP-binding protein of...
, Ran (biology)
Ran (biology)
Ran is a small 25Kda protein that is involved in transport into and out of the cell nucleus during interphase and also involved in mitosis. It is a member of the Ras superfamily....
, RANBP1
RANBP1
Ran-specific binding protein 1 is an enzyme that in humans is encoded by the RANBP1 gene.-Interactions:RANBP1 has been shown to interact with XPO1, KPNB1 and Ran.-Further reading:...
, NUP50
NUP50
Nucleoporin 50 kDa is a protein that in humans is encoded by the NUP50 gene.-Interactions:NUP50 has been shown to interact with KPNB1 and CDKN1B.-Further reading:...
, P53
P53
p53 , is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer...
, NUP153
NUP153
NUP153, is a human gene that codes for the 153 kDa protein Nucleoporin 153kDa.-Interactions:NUP153 has been shown to interact with SENP2 and KPNB1.-Further reading:...
and Mothers against decapentaplegic homolog 3
Mothers against decapentaplegic homolog 3
Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins.The human SMAD3 gene is located on chromosome 15...
.