Lemont Kier
Encyclopedia
Lemont Kier is an American chemist and leader in the field of Drug Design
and Medicinal Chemistry
. He is the recipient of the American Association of Pharmaceutical Scientists 2008 Research Achievement Award in Drug Development and Discovery. He obtained his PhD in Medicinal Chemistry at the University of Minnesota
in 1958. He is currently a Professor of Medicinal Chemistry and Nurse Anesthesia at the Virginia Commonwealth University
in Richmond
.Professor Kier built one of the first models in which molecular orbital theory was applied successfully to drug design and development. In this model, he and his colleague developed what is now called the "Kier-Hall Index" to describe molecular connectivity. His particular expertise in the question “How do chemical modifications affect particular physical properties of drugs?” has been used by Prof. Kier and others to develop the theory of the interaction of general anesthetic gases with the body, and the theory of taste (and in particular, sweetness ).
Professor Kier is the author or co-author of eight books: Molecular Orbital Theory In Drug Research; Molecular Connectivity In Chemistry and Drug Research; Molecular Connectivity in Structure Activity Analysis; Molecular Structure Description: The Electrotopological State; Medicinal Chemistry and Physics for Nurse Anesthetists; Cellular Automata Modeling of Chemical Systems; and Science and Complexity for Life Science Students.
Drug design
Drug design, also sometimes referred to as rational drug design or structure-based drug design, is the inventive process of finding new medications based on the knowledge of the biological target...
and Medicinal Chemistry
Medicinal chemistry
Medicinal chemistry and pharmaceutical chemistry are disciplines at the intersection of chemistry, especially synthetic organic chemistry, and pharmacology and various other biological specialties, where it is involved with design, chemical synthesis and development for market of pharmaceutical...
. He is the recipient of the American Association of Pharmaceutical Scientists 2008 Research Achievement Award in Drug Development and Discovery. He obtained his PhD in Medicinal Chemistry at the University of Minnesota
University of Minnesota
The University of Minnesota, Twin Cities is a public research university located in Minneapolis and St. Paul, Minnesota, United States. It is the oldest and largest part of the University of Minnesota system and has the fourth-largest main campus student body in the United States, with 52,557...
in 1958. He is currently a Professor of Medicinal Chemistry and Nurse Anesthesia at the Virginia Commonwealth University
Virginia Commonwealth University
Virginia Commonwealth University is a public university located in Richmond, Virginia. It comprises two campuses in the Downtown Richmond area, the product of a merger between the Richmond Professional Institute and the Medical College of Virginia in 1968...
in Richmond
Richmond, Virginia
Richmond is the capital of the Commonwealth of Virginia, in the United States. It is an independent city and not part of any county. Richmond is the center of the Richmond Metropolitan Statistical Area and the Greater Richmond area...
.Professor Kier built one of the first models in which molecular orbital theory was applied successfully to drug design and development. In this model, he and his colleague developed what is now called the "Kier-Hall Index" to describe molecular connectivity. His particular expertise in the question “How do chemical modifications affect particular physical properties of drugs?” has been used by Prof. Kier and others to develop the theory of the interaction of general anesthetic gases with the body, and the theory of taste (and in particular, sweetness ).
Professor Kier is the author or co-author of eight books: Molecular Orbital Theory In Drug Research; Molecular Connectivity In Chemistry and Drug Research; Molecular Connectivity in Structure Activity Analysis; Molecular Structure Description: The Electrotopological State; Medicinal Chemistry and Physics for Nurse Anesthetists; Cellular Automata Modeling of Chemical Systems; and Science and Complexity for Life Science Students.
External links
- http://kier.rascientific.com
- http://www.phc.vcu.edu/Faculty/Kier.html