List of antiviral drugs
Encyclopedia

A

  • Abacavir
    Abacavir
    Abacavir is a nucleoside analog reverse transcriptase inhibitor used to treat HIV and AIDS. It is available under the trade name Ziagen and in the combination formulations Trizivir and Kivexa/Epzicom...

     - anti-HIV. NRTI drug. "Ziagen" (ViiV Healthcare). In combination formulations: "Trizivir" and "Kivexa/Epzicom"
  • Aciclovir
    Aciclovir
    Aciclovir or acyclovir , chemical name acycloguanosine, abbreviated as ACV,is a guanosine analogue antiviral drug, marketed under trade names such as Cyclovir, Herpex, Acivir, Acivirax, Zovirax, and Zovir...

     - anti-HSV.
  • Acyclovir
  • Adefovir
    Adefovir
    Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered nucleotide analog reverse transcriptase inhibitor .-Uses:...

  • Amantadine
    Amantadine
    Amantadine is the organic compound known formally as 1-adamantylamine or 1-aminoadamantane. The molecule consists of adamantane backbone that has an amino group substituted at one of the four methyne positions. This pharmaceutical is sold under the name Symmetrel for use both as an antiviral and an...

  • Amprenavir
  • Ampligen
    Ampligen
    Rintatolimod , is an experimental immunomodulatory double stranded RNA drug developed by Hemispherx Biopharma of Philadelphia, Pennsylvania...

  • Arbidol
    Arbidol
    Arbidol is an antiviral treatment for influenza infection used in Russia and China. The drug is manufactured by Moscow-based Masterlek . Although some Russian studies have shown it to be effective, it is not approved for use in Western countries. Chemically, arbidol features an indole core,...

  • Atazanavir
    Atazanavir
    Atazanavir, marketed under the trade name Reyataz by Bristol Myers, is an antiretroviral drug of the protease inhibitor class...

  • Atripla
    Atripla
    Emtricitabine/tenofovir/efavirenz is a fixed-dose combination drug for the treatment of HIV infection. It combines Gilead Sciences's tenofovir and emtricitabine with Bristol-Myers Squibb's efavirenz into a fixed-dose pill...

     (fixed dose drug)

E

  • Edoxudine
    Edoxudine
    Edoxudine is an Antiviral drug.It has shown effectiveness against herpes simplex virus.-Synthesis:-References:...

  • Efavirenz
    Efavirenz
    Efavirenz is a non-nucleoside reverse transcriptase inhibitor and is used as part of highly active antiretroviral therapy for the treatment of a human immunodeficiency virus type 1....

  • Emtricitabine
    Emtricitabine
    Emtricitabine , with trade name Emtriva , is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children....

  • Enfuvirtide
    Enfuvirtide
    Enfuvirtide is an HIV fusion inhibitor, the first of a novel class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection. It is marketed under the trade name Fuzeon ....

  • Entecavir
    Entecavir
    Entecavir INN , abbreviated ETV, is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude ....

  • Entry inhibitors
    Entry inhibitors
    Entry inhibitors, also known as fusion inhibitors, are a class of antiretroviral drugs, used in combination therapy for the treatment of HIV infection. This class of drugs interferes with the binding, fusion and entry of an HIV virion to a human cell...


F

  • Famciclovir
    Famciclovir
    Famciclovir is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster . It is a prodrug form of penciclovir with improved oral bioavailability...

  • Fixed dose combination (antiretroviral)
    Fixed dose combination (antiretroviral)
    Fixed-dose combinations of antiretrovirals are multiple antiretroviral drugs combined into a single pill, which helps reduce pill burden. They may combine different classes of antiretrovirals or contain only a single class. Licensed fixed-dose combinations are shown in the table below....

  • Fomivirsen
    Fomivirsen
    Fomivirsen is an antiviral drug. It is used in the treatment of cytomegalovirus retinitis in immunocompromised patients, including those with AIDS...

  • Fosamprenavir
    Fosamprenavir
    Fosamprenavir , under the trade names Lexiva and Telzir is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir. The FDA approved it October 20, 2003, while the EMEA approved it on July 12, 2004...

  • Foscarnet
    Foscarnet
    Foscarnet is the conjugate base of the chemical compound with the formula HO2CPO3H2.-Uses:This phosphonic acid derivative is an antiviral medication used to treat herpes viruses, including drug resistant cytomegalovirus and herpes simplex viruses types 1 and 2...

  • Fosfonet
  • Fusion inhibitor

I

  • Ibacitabine
    Ibacitabine
    Ibacitabine is an Antiviral drug.-External links:...

  • Imunovir
  • Idoxuridine
    Idoxuridine
    Idoxuridine is an anti-herpesvirus antiviral drug.It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to...

  • Imiquimod
    Imiquimod
    Imiquimod is a prescription medication that acts as an immune response modifier. It is marketed by Meda AB, Graceway Pharmaceuticals and iNova Pharmaceuticals under the trade names Aldara and Zyclara, and by Mochida as Beselna. It is also referred to as R-837.- History :The original FDA approval...

  • Indinavir
    Indinavir
    Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV infection and AIDS.-History:...

  • Inosine
    Inosine
    Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring via a β-N9-glycosidic bond....

  • Integrase inhibitor
    Integrase inhibitor
    Integrase inhibitors are a class of antiretroviral drug designed to block the action of integrase, a viral enzyme that inserts the viral genome into the DNA of the host cell. Since integration is a vital step in retroviral replication, blocking it can halt further spread of the virus...

  • Interferon type III
    Interferon type III
    The recently classified type III interferon group consists of three IFN-λ molecules called IFN-λ1, IFN-λ2 and IFN-λ3 . These IFNs signal through a receptor complex consisting of IL10R2 and IFNLR1...

  • Interferon type II
    Interferon type II
    A sole member makes up the type II IFNs that is called IFN-γ . Mature IFN-γ is an anti-parallel homodimer, which binds to the IFN-γ receptor complex to elicit a signal within its target cell...

  • Interferon type I
    Interferon type I
    Human type I interferons comprise a vast and growing group of IFN proteins.All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor that consists of IFNAR1 and IFNAR2 chains....

  • Interferon
    Interferon
    Interferons are proteins made and released by host cells in response to the presence of pathogens—such as viruses, bacteria, or parasites—or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.IFNs belong to...


P

  • Peginterferon alfa-2a
  • Penciclovir
  • Peramivir
    Peramivir
    Peramivir is an experimental antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. It has been authorized for the emergency use of treatment of certain hospitalized patients with known or suspected 2009 H1N1 influenza....

  • Pleconaril
  • Podophyllotoxin
    Podophyllotoxin
    Podophyllotoxin , otherwise known as podofilox, is a non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species. Under the trade name Condylox, a topical gel, it is used on the skin to treat external genital warts, caused by some types of the human papillomavirus...

  • Protease inhibitor (pharmacology)
    Protease inhibitor (pharmacology)
    Protease inhibitors are a class of drugs used to treat or prevent infection by viruses, including HIV and Hepatitis C. PIs prevent viral replication by inhibiting the activity of proteases, e.g.HIV-1 protease, enzymes used by the viruses to cleave nascent proteins for final assembly of new...


R

  • Raltegravir
  • Reverse transcriptase inhibitor
    Reverse transcriptase inhibitor
    Reverse-transcriptase inhibitors are a class of antiretroviral drug used to treat HIV infection, tumors, and cancer. RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce.-Mechanism:...

  • Ribavirin
    Ribavirin
    Ribavirin is an anti-viral drug indicated for severe RSV infection , hepatitis C infection and other viral infections. Ribavirin is a prodrug, which when metabolised resembles purine RNA nucleotides...

  • Rimantadine
    Rimantadine
    Rimantadine is an orally administered antiviral drug used to treat, and in rare cases prevent, influenzavirus A infection. When taken within one to two days of developing symptoms, rimantadine can shorten the duration and moderate the severity of influenza. Both rimantadine and the similar drug...

  • Ritonavir
    Ritonavir
    Ritonavir, with trade name Norvir , is an antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS....

  • Pyramidine

T

  • Tea tree oil
    Tea tree oil
    Tea tree oil, or melaleuca oil, is a pale yellow colour to nearly clear essential oil with a fresh camphoraceous odor. It is taken from the leaves of the Melaleuca alternifolia, which is native to the northeast coast of New South Wales, Australia...

  • Tenofovir
  • Tenofovir disoproxil
  • Tipranavir
    Tipranavir
    Tipranavir, or tipranavir disodium, is a nonpeptidic protease inhibitor manufactured by Boehringer-Ingelheim under the trade name Aptivus...

  • Trifluridine
    Trifluridine
    Trifluridine is an anti-herpesvirus antiviral drug, used primarily on the eye. It was sold under the trade name, Viroptic, by Glaxo Wellcome, now merged into GlaxoSmithKline...

  • Trizivir
    Trizivir
    Abacavir/lamivudine/zidovudine is a pharmaceutical treatment for HIV infection. It is a fixed dose combination of three reverse transcriptase inhibitors patented by GlaxoSmithKline and now marketed by its joint venture with Pfizer, ViiV Healthcare:*abacavir *lamivudine *zidovudine It is indicated...

  • Tromantadine
    Tromantadine
    Tromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade name Viru-Merz. Its performance is similar to aciclovir.Like rimantadine and amantadine, tromantadine is a derivative of adamantane....

  • Truvada
    Truvada
    Tenofovir/emtricitabine, trademark Truvada, is a fixed-dose combination of two antiretroviral drugs used for the treatment of HIV. It consists of 300 milligrams of tenofovir and 200 milligrams of emtricitabine. By combining the two agents into one tablet, it reduces the pill burden and increases...


V

  • Valaciclovir (Valtrex)
  • Valganciclovir
    Valganciclovir
    Valganciclovir hydrochloride is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir...

  • Vicriviroc
    Vicriviroc
    Vicriviroc, previously named SCH 417690 and SCH-D, is a pyrimidine CCR5 entry inhibitor of HIV-1. It was developed by the pharmaceutical company Schering-Plough. Merck decided to not pursue regulatory approval for use in treatment-experienced patients because the drug did not meet primary efficacy...

  • Vidarabine
    Vidarabine
    Vidarabine or adenine arabinoside is an antiviral drug which is active against herpes simplex and varicella zoster viruses.- How the drug was discovered :...

  • Viramidine
    Viramidine
    Taribavirin is an antiviral drug in Phase III human trials, but not yet approved for pharmaceutical use. It is a prodrug of ribavirin, active against a number of DNA and RNA viruses...

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