Methylenomycin A
Encyclopedia
Methylenomycin A is a cyclopentanoid antibiotic produced by Streptomyces coelicolor
A3(2) that is effective against both Gram-negative
and Gram-positive
bacteria. Methylenomycins are naturally produced in two variants: A and B.
Streptomyces coelicolor
Streptomyces coelicolor is a soil-dwelling Gram-positive bacterium that belongs to the genus Streptomyces.-Usage in biotechnology:Strains of S. coelicolor produce various antibiotics, including actinorhodin, methylenomycin, undecylprodigiosin, and perimycin. Certain strains of S. coelicolor can...
A3(2) that is effective against both Gram-negative
Gram-negative
Gram-negative bacteria are bacteria that do not retain crystal violet dye in the Gram staining protocol. In a Gram stain test, a counterstain is added after the crystal violet, coloring all Gram-negative bacteria with a red or pink color...
and Gram-positive
Gram-positive
Gram-positive bacteria are those that are stained dark blue or violet by Gram staining. This is in contrast to Gram-negative bacteria, which cannot retain the crystal violet stain, instead taking up the counterstain and appearing red or pink...
bacteria. Methylenomycins are naturally produced in two variants: A and B.