Miprocin
Encyclopedia
Miprocin is a substituted aromatic compound and a lesser-known psychedelic drug
from the tryptamine
family. Miprocin is part of the class of drugs known as serotonergic psychedelics (which includes magic mushrooms, LSD
and mescaline
), and its effects and molecular structure resemble that of the tryptamine
psilocin
. To date, there have been no reports of deaths from 4-HO-MiPT.
by Alexander Shulgin
. In his book TIHKAL
(Tryptamines I Have Known and Loved). 4-HO-MiPT is a synthetic psychedelic considered similar in activity to psilocin. It is relatively uncommon and has only a short history of human use.
analog
of the chemical N-Methyl-N-isopropyltryptamine
as well as the structural analog of 4-HO-DMT.
. Its method of action comes from its partial agonist activity at 5-HT2A serotonin receptors and serotonin
neurotransmitter
s located in the prefrontal cortex
in the human brain
.
and it isn't known to be associated with compulsive use and physical dependence however, this being a research chemical and because its use is so uncommon, it should therfore be considered & treated like an experimental chemical. Although some people are willing to ingest these chemicals for their effects, it is not reasonable to assume that these chemicals are in any way 'safe' to use recreationally.
of psilocin, in which case could lead to persecution under the Analog Act
of the USA.
The substance could also be considered illegal in the UK
under the Misuse of Drugs Act 1971
.
Miprocin was scheduled as "hälsofarliga varor" (health-threatening substances, having no acceptable medical use) in Sweden
on Nov 1, 2005.
Psychedelics, dissociatives and deliriants
This general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness...
from the tryptamine
Tryptamine
Tryptamine is a monoamine alkaloid found in plants, fungi, and animals. It is based around the indole ring structure, and is chemically related to the amino acid tryptophan, from which its name is derived...
family. Miprocin is part of the class of drugs known as serotonergic psychedelics (which includes magic mushrooms, LSD
LSD
Lysergic acid diethylamide, abbreviated LSD or LSD-25, also known as lysergide and colloquially as acid, is a semisynthetic psychedelic drug of the ergoline family, well known for its psychological effects which can include altered thinking processes, closed and open eye visuals, synaesthesia, an...
and mescaline
Mescaline
Mescaline or 3,4,5-trimethoxyphenethylamine is a naturally occurring psychedelic alkaloid of the phenethylamine class used mainly as an entheogen....
), and its effects and molecular structure resemble that of the tryptamine
Tryptamine
Tryptamine is a monoamine alkaloid found in plants, fungi, and animals. It is based around the indole ring structure, and is chemically related to the amino acid tryptophan, from which its name is derived...
psilocin
Psilocin
Psilocin , an aromatic compound, sometimes also spelled psilocine, psilocyn, or psilotsin, is a psychedelic mushroom alkaloid. It is found in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin...
. To date, there have been no reports of deaths from 4-HO-MiPT.
History
4-HO-MiPT was first synthesizedChemical synthesis
In chemistry, chemical synthesis is purposeful execution of chemical reactions to get a product, or several products. This happens by physical and chemical manipulations usually involving one or more reactions...
by Alexander Shulgin
Alexander Shulgin
Alexander "Sasha" Theodore Shulgin is an American pharmacologist, chemist, artist, and drug developer.Shulgin is credited with the popularization of MDMA, commonly known as ecstasy, in the late 1970s and early 1980s, especially for psychopharmaceutical use and the treatment of depression and...
. In his book TIHKAL
TiHKAL
TiHKAL: The Continuation is a 1997 book written by Alexander Shulgin and Ann Shulgin about a family of psychoactive drugs known as tryptamines. A sequel to PiHKAL: A Chemical Love Story, TiHKAL is an acronym that stands for Tryptamines I Have Known and Loved.-Content:TiHKAL, much like its...
(Tryptamines I Have Known and Loved). 4-HO-MiPT is a synthetic psychedelic considered similar in activity to psilocin. It is relatively uncommon and has only a short history of human use.
Chemistry
Miprocin is the 4-hydroxylHydroxyl
A hydroxyl is a chemical group containing an oxygen atom covalently bonded with a hydrogen atom. In inorganic chemistry, the hydroxyl group is known as the hydroxide ion, and scientists and reference works generally use these different terms though they refer to the same chemical structure in...
analog
Analog (chemistry)
In chemistry, a structural analog , also known as chemical analog or simply analog, is a compound having a structure similar to that of another one, but differing from it in respect of a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced...
of the chemical N-Methyl-N-isopropyltryptamine
N-Methyl-N-isopropyltryptamine
N-Methyl-N-isopropyltryptamine is a psychedelic tryptamine, closely related to DMT, DIPT and Miprocin.-Chemistry:MiPT base, unlike many other tryptamines in their freebase form, does not decompose rapidly in the presence of light in oxygen....
as well as the structural analog of 4-HO-DMT.
Pharmacology
Miprocin is a serotonergicSerotonergic
Serotonergic or serotoninergic means "related to the neurotransmitter serotonin". A synapse is serotonergic if it uses serotonin as its neurotransmitter...
. Its method of action comes from its partial agonist activity at 5-HT2A serotonin receptors and serotonin
Serotonin
Serotonin or 5-hydroxytryptamine is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system of animals including humans...
neurotransmitter
Neurotransmitter
Neurotransmitters are endogenous chemicals that transmit signals from a neuron to a target cell across a synapse. Neurotransmitters are packaged into synaptic vesicles clustered beneath the membrane on the presynaptic side of a synapse, and are released into the synaptic cleft, where they bind to...
s located in the prefrontal cortex
Prefrontal cortex
The prefrontal cortex is the anterior part of the frontal lobes of the brain, lying in front of the motor and premotor areas.This brain region has been implicated in planning complex cognitive behaviors, personality expression, decision making and moderating correct social behavior...
in the human brain
Brain
The brain is the center of the nervous system in all vertebrate and most invertebrate animals—only a few primitive invertebrates such as sponges, jellyfish, sea squirts and starfishes do not have one. It is located in the head, usually close to primary sensory apparatus such as vision, hearing,...
.
Toxicity
Very little is known about the overrall toxicity of Miprocin. The chemicial structure of it is very similar to PsilocinPsilocin
Psilocin , an aromatic compound, sometimes also spelled psilocine, psilocyn, or psilotsin, is a psychedelic mushroom alkaloid. It is found in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin...
and it isn't known to be associated with compulsive use and physical dependence however, this being a research chemical and because its use is so uncommon, it should therfore be considered & treated like an experimental chemical. Although some people are willing to ingest these chemicals for their effects, it is not reasonable to assume that these chemicals are in any way 'safe' to use recreationally.
Dosage
| Miprocin (Fumarate) | Oral Dose |
|---|---|
| Threshold | 5 mg-10 mg |
| Light | 9 mg-14 mg |
| Common | 12 mg-20 mg |
| Strong | 18 mg-30 mg |
| Heavy | 25 mg+ |
| Onset | After Effects |
| 15 - 45 minutes (depending on stomach contents) | 1 - 4 hours |
Positive
- PsilocybinPsilocybinPsilocybin is a naturally occurring psychedelic prodrug, with mind-altering effects similar to those of LSD and mescaline, after it is converted to psilocin. The effects can include altered thinking processes, perceptual distortions, an altered sense of time, and spiritual experiences, as well as...
-like Open & Closed-eye visuals - Creative or abstract thinking
- Increased giggling and laughing
- Out of body experience, light disassociation (if desired)
- Mood lift, euphoriaEuphoria (emotion)Euphoria is medically recognized as a mental and emotional condition in which a person experiences intense feelings of well-being, elation, happiness, ecstasy, excitement and joy...
- Intensification of tactile sensations, smellOlfactionOlfaction is the sense of smell. This sense is mediated by specialized sensory cells of the nasal cavity of vertebrates, and, by analogy, sensory cells of the antennae of invertebrates...
, etc - Increased appetite
- Heighten sexSexIn biology, sex is a process of combining and mixing genetic traits, often resulting in the specialization of organisms into a male or female variety . Sexual reproduction involves combining specialized cells to form offspring that inherit traits from both parents...
ual interest - Diminished aggression, hostility, and jealousy
- Diminished fear, anxiety, and insecurity
- Substantial enhancement of the appreciation for quality of music
Neutral
- Sedation
- MydriasisMydriasisMydriasis is a dilation of the pupil due to disease, trauma or the use of drugs. Normally, the pupil dilates in the dark and constricts in the light to respectively improve vividity at night and to protect the retina from sunlight damage during the day...
- Colour alteration
- Time perception alteration
- SynesthesiaSynesthesiaSynesthesia , from the ancient Greek , "together," and , "sensation," is a neurologically based condition in which stimulation of one sensory or cognitive pathway leads to automatic, involuntary experiences in a second sensory or cognitive pathway...
- Feelings of body twitching
- General change in consciousness
- Auditory distortions, pitchPitch (music)Pitch is an auditory perceptual property that allows the ordering of sounds on a frequency-related scale.Pitches are compared as "higher" and "lower" in the sense associated with musical melodies,...
shifts - Visual distortions, open and closed-eye patterning, movement trails, shifting colors
Side Effects
- Body tremors
- Mild vertigoVertigoVertigo is a form of dizziness.Vertigo may also refer to:* Vertigo , a 1958 film by Alfred Hitchcock**Vertigo , its soundtrack** Vertigo effect, or Dolly zoom, a special effect in film, named after the movie...
- Slight headache / nausea
- Possible confusion
- Light-headedness
- Possible xerostomiaXerostomiaXerostomia is the medical term for the subjective complaint of dry mouth due to a lack of saliva. Xerostomia is sometimes colloquially called pasties, cottonmouth, drooth, or doughmouth. Several diseases, treatments, and medications can cause xerostomia. It can also be exacerbated by smoking or...
- May exacerbate latent or existing mental disorders
- Possible minor jaw-clenching
- Slight rise in body tempature
Duration
The duration is listed as 4-6 hours, although other sources list the duration as 5-8 hours, depending on certain variables (such as metabolism, food interaction).Legality
4-HO-MiPT is a unscheduled drug in the United States. It may be considered an analogAnalog (chemistry)
In chemistry, a structural analog , also known as chemical analog or simply analog, is a compound having a structure similar to that of another one, but differing from it in respect of a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced...
of psilocin, in which case could lead to persecution under the Analog Act
Federal Analog Act
The Federal Analog Act, , is a controversial section of the United States Controlled Substances Act which allowed any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were also listed in those schedules, but only if intended for human...
of the USA.
The substance could also be considered illegal in the UK
United Kingdom
The United Kingdom of Great Britain and Northern IrelandIn the United Kingdom and Dependencies, other languages have been officially recognised as legitimate autochthonous languages under the European Charter for Regional or Minority Languages...
under the Misuse of Drugs Act 1971
Misuse of Drugs Act 1971
The Misuse of Drugs Act 1971 is an Act of Parliament which represents UK action in line with treaty commitments under the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic...
.
Miprocin was scheduled as "hälsofarliga varor" (health-threatening substances, having no acceptable medical use) in Sweden
Sweden
Sweden , officially the Kingdom of Sweden , is a Nordic country on the Scandinavian Peninsula in Northern Europe. Sweden borders with Norway and Finland and is connected to Denmark by a bridge-tunnel across the Öresund....
on Nov 1, 2005.
See also
- MiPTMIPT- Institutes :* Moscow Institute of Physics and Technology * National Memorial Institute for the Prevention of Terrorism...
- 4-MeO-MiPT4-MeO-MiPT4-MeO-MiPT, or 4-methoxy-N-methyl-N-isopropyltryptamine, is a lesser-known psychedelic drug. It is the 4-methoxy analog of MiPT. 4-MeO-MiPT was first synthesized by Alexander Shulgin. In his book TiHKAL , the minimum dosage is listed as 20-30 mg, and the duration listed as 4–6 hours...
- 5-MeO-MiPT5-MeO-MIPT5-MeO-MiPT is a psychedelic and hallucinogenic drug, used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs 5-MeO-DiPT, DiPT, and MiPT...
- DimethyltryptamineDimethyltryptamineN,N-Dimethyltryptamine is a naturally occurring psychedelic compound of the tryptamine family. DMT is found in several plants, and also in trace amounts in humans and other mammals, where it is originally derived from the essential amino acid tryptophan, and ultimately produced by the enzyme INMT...
- PsilocybinPsilocybinPsilocybin is a naturally occurring psychedelic prodrug, with mind-altering effects similar to those of LSD and mescaline, after it is converted to psilocin. The effects can include altered thinking processes, perceptual distortions, an altered sense of time, and spiritual experiences, as well as...
- PsilocinPsilocinPsilocin , an aromatic compound, sometimes also spelled psilocine, psilocyn, or psilotsin, is a psychedelic mushroom alkaloid. It is found in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin...
- Metocin4-HO-MET4-HO-MET, or 4-hydroxy-N-methyl-N-ethyltryptamine, also known as metocin, is a lesser-known psychedelic drug. It is a structural− and functional analog of psilocin as well the 4-hydroxyl analog of MET. 4-HO-MET was first synthesized by Alexander Shulgin...
- TiHKALTiHKALTiHKAL: The Continuation is a 1997 book written by Alexander Shulgin and Ann Shulgin about a family of psychoactive drugs known as tryptamines. A sequel to PiHKAL: A Chemical Love Story, TiHKAL is an acronym that stands for Tryptamines I Have Known and Loved.-Content:TiHKAL, much like its...
- Psychedelic drugPsychedelic drugA psychedelic substance is a psychoactive drug whose primary action is to alter cognition and perception. Psychedelics are part of a wider class of psychoactive drugs known as hallucinogens, a class that also includes related substances such as dissociatives and deliriants...
- Psychoactive drugPsychoactive drugA psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that crosses the blood–brain barrier and acts primarily upon the central nervous system where it affects brain function, resulting in changes in perception, mood, consciousness, cognition, and behavior...
- Psychedelics, Dissociatives and DeliriantsPsychedelics, dissociatives and deliriantsThis general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness...