Myf6
Encyclopedia
Myf6, myogenic factor 6 (also known in the medical literature as MRF4 and herculin), is a myogenic regulatory factor (MRF).
s (MYF) family that regulate myogenesis
and muscle regeneration. Myogenic factor are basic-helix-loop-helix
(bHLH) transcription factor
s
Function
MYF6 is a member of the myogenic factorMyogenic regulatory factors
Myogenic regulatory factors are basic-helix-loop-helix transcription factors that regulate myogenesis: MyoD, Myf5, myogenin, and MRF4.These proteins contain a conserved basic DNA binding domain that binds the E box DNA motif . They dimerize with other HLH containing proteins through an HLH-HLH...
s (MYF) family that regulate myogenesis
Myogenesis
Myogenesis is the formation of muscular tissue, in particular during embryonic development.Muscle fibers form from the fusion of myoblasts into multi-nucleated fibers . In the early development of an embryo these myoblasts will proliferate if enough fibroblast growth factor is present...
and muscle regeneration. Myogenic factor are basic-helix-loop-helix
Basic-helix-loop-helix
A basic helix-loop-helix is a protein structural motif that characterizes a family of transcription factors.- Structure :The motif is characterized by two α-helices connected by a loop. In general, transcription factors including this domain are dimeric, each with one helix containing basic amino...
(bHLH) transcription factor
Transcription factor
In molecular biology and genetics, a transcription factor is a protein that binds to specific DNA sequences, thereby controlling the flow of genetic information from DNA to mRNA...
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