Nuage
Encyclopedia
Nuage is a specific term for Drosophila melanogaster
germline granules. Nuage are the hallmark of Drosophila melanogaster germline cells, which have an electron-dense perinuclear structure and can silence the selfish genetic elements in Drosophila melanogaster. The term 'Nuage' comes from the French word for 'cloud', as they appear as nebulous electron-dense bodies by electron microscopy. They are found in nurse cells
of the developing Drosophila melanogaster egg chamber and are composed of various types of proteins, including RNA-helicases, Tudor domain
proteins, Piwi
-clade Argonaute
proteins, in addition to a PRMT5 methylosome composed of Capsuléen and its co-factor, Valois (MEP50
).
Drosophila melanogaster
Drosophila melanogaster is a species of Diptera, or the order of flies, in the family Drosophilidae. The species is known generally as the common fruit fly or vinegar fly. Starting from Charles W...
germline granules. Nuage are the hallmark of Drosophila melanogaster germline cells, which have an electron-dense perinuclear structure and can silence the selfish genetic elements in Drosophila melanogaster. The term 'Nuage' comes from the French word for 'cloud', as they appear as nebulous electron-dense bodies by electron microscopy. They are found in nurse cells
Nurse cell
-Human physiology:Nurse cells are specialized macrophages residing in the bone marrow that assist in the development of red blood cells. They absorb the nuclei of immature red blood cells and may provide growth factors to help the red blood cells mature...
of the developing Drosophila melanogaster egg chamber and are composed of various types of proteins, including RNA-helicases, Tudor domain
Tudor domain
A tudor domain is a conserved protein structural motif originally identified as a region of 50 amino acids found in the Tudor protein encoded in Drosophila...
proteins, Piwi
Piwi
The piwi class of genes was originally identified as encoding regulatory proteins responsible for maintaining incomplete differentiation in stem cells and maintaining the stability of cell division rates in germ line cells...
-clade Argonaute
Argonaute
Argonaute proteins are the catalytic components of the RNA-induced silencing complex , the protein complex responsible for the gene silencing phenomenon known as RNA interference . Argonaute proteins bind different classes of small non-coding RNAs, including microRNAs , small interfering RNAs and...
proteins, in addition to a PRMT5 methylosome composed of Capsuléen and its co-factor, Valois (MEP50
WD repeat-containing protein 77
Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene.-Interactions:WD repeat-containing protein 77 has been shown to interact with CTDP1 and Protein arginine methyltransferase 5.-Further reading:...
).