Paul Frederick White
Encyclopedia
Paul Frederick White, FANZCA
is a researcher in anesthesiology, Director of Research at Cedars-Sinai Medical Center at Los Angeles, retired professor and the holder of the Margaret Milam McDermott
Distinguished Chair of Anesthesiology at The University of Texas Southwestern Medical Center at Dallas, and the author and editor of several journals and textbooks on the subject. With over 350 peer-reviewed publications and authorship in 9 anesthesiology textbooks, White has helped shape and revolutionize the field of ambulatory anesthesia and intravenous anesthesia.
with Distinction in 1970. He subsequently earned his PhD
(Pharmacology) and MD
degrees from the University of California, San Francisco
. White obtained postgraduate training in both Internal Medicine and Anesthesiology at UC San Francisco, and has board certification in both medical specialties. In 1980, he joined the faculty at Stanford University
and became a tenured Associate Professor and Chief of the Outpatient Anesthesiology Service at the University Hospital. In 1988, he accepted the position of Professor and Vice-Chair of Clinical Research in the Department of Anesthesiology at Washington University in St. Louis. He also served as the Medical Director of the Barnes Hospital
Day Surgery Center. In 1992, he was appointed Professor and Chairman of the Department of Anesthesiology and Pain Management at the University of Texas Southwestern Medical Center
. In June 2011, he retired from the Margaret Milam McDermott
Distinguished Chair of Anesthesiology at UT Southwestern
. He serves as a representative from the Department on the advisory board of the institution's new Center for Minimally Invasive Surgery. White has also served as a non-paid consultant to the Departments of Anesthesia at both Ohio State University
(for ambulatory surgery) and Cedars Sinai Medical Center in Los Angeles (for clinical research and continuing education programs). He has an appointment as a Director of Research at Cedars Sinai Medical Center for the Department of Anesthesiology.
White has edited nine books, including major textbooks on the subspecialties of ambulatory anesthesia and intravenous anesthesia. White has also contributed 88 chapters to textbooks edited by colleagues from around the world. In addition to publishing over 350 peer-reviewed articles, White has written 14 editorials and published over 500 scientific abstracts. Two of White's peer-reviewed publications were listed among the "Top 10" most cited articles in Anesthesiology (and he has the second most citations by any individual author in the specialty). White studies have appeared in USA Today, Washington Post, Wall Street Journal, and other media outlets. White has trained more than 65 postgraduate clinical research fellows during his academic career. He has given over 450 domestic and 250 international lectures. In addition, White has performed over 100 Visiting Professorships in the United States and abroad. White is acknowledged by his colleagues as an international leader in the fields of ambulatory anesthesia and pain management, and has been recognized in the "Best Doctors in America" and "Who's Who in North America." He was awarded the Distinguished Service Award by the Society for Ambulatory Anesthesia, and the Dannemiller Memorial Foundation's award for "Educational Excellence in Anesthesiology."
White has served on the Board of Directors of three major anesthesia organizations (namely, the Society for Ambulatory Anesthesia [SAMBA], the Society for Intravenous Anesthesia [SIVA], and the International Society for Anaesthetic Pharmacology [ISAP]). White served as the President of the SAMBA organization from 1994–95 and as President of SIVA/ISAP from 1999-2000. In addition, White has served as Chairman of the Anesthesiology Panel (1985–2000) and was a member of the Executive Committee of the United States Pharmacopoeia (1995–2000). White has been appointed to five international editorial boards and currently serves as the Section Editor for Ambulatory Anesthesia for Anesthesia & Analgesia and the Journal of Clinical Anesthesia. Finally, White has established a nonprofit foundation (the White Mountain Institute ) to advance education in the creative arts and medicine throughout the world.
White's brother, Ed White (football)
, is a former UC Berkeley hall of fame and NFL all pro offensive lineman who played for the San Diego Chargers
and Minnesota Vikings
.
guilty of the involuntary manslaughter of Michael Jackson
. White testified that the models used by the prosecution’s expert, Dr. Steven Shafer, did not show how Jackson would have responded to the drug propofol
. White was one of the first to test propofol, and his clinical trial led to approval of the drug by the Food and Drug Administration
. White also stated that Murray’s treatment of Jackson with propofol was not inappropriate because off-label drug use by doctors is not uncommon or illegal.
In his second day on the stand, White testified that Jackson probably caused his death by injecting himself with propofol while Murray was not looking. White based his conclusion on the level of propofol in Jackson’s urine during the autopsy. White also testified that Jackson had taken several tablets of Lorazepam
, a sedative, which, in conjunction with the propofol, would have killed Jackson instantly.
On cross-examination, White conceded that Murray had violated the standard of medical care by administering propofol in a home setting.
At a hearing on November 16, 2011, Judge Michael Pastor found White in contempt for referring to his discussions with Murray during White's testimony, even though had been warned not to do so. He was fined $250.
Australian and New Zealand College of Anaesthetists
The Australian and New Zealand College of Anaesthetists is responsible for examining and qualifying anaesthetists in Australia and New Zealand. The College maintains standards of practice in anaesthesia.-Membership:...
is a researcher in anesthesiology, Director of Research at Cedars-Sinai Medical Center at Los Angeles, retired professor and the holder of the Margaret Milam McDermott
Distinguished Chair of Anesthesiology at The University of Texas Southwestern Medical Center at Dallas, and the author and editor of several journals and textbooks on the subject. With over 350 peer-reviewed publications and authorship in 9 anesthesiology textbooks, White has helped shape and revolutionize the field of ambulatory anesthesia and intravenous anesthesia.
Education and career
White graduated from an honors program in Biochemistry at the University of California, BerkeleyUniversity of California, Berkeley
The University of California, Berkeley , is a teaching and research university established in 1868 and located in Berkeley, California, USA...
with Distinction in 1970. He subsequently earned his PhD
Doctor of Philosophy
Doctor of Philosophy, abbreviated as Ph.D., PhD, D.Phil., or DPhil , in English-speaking countries, is a postgraduate academic degree awarded by universities...
(Pharmacology) and MD
Doctor of Medicine
Doctor of Medicine is a doctoral degree for physicians. The degree is granted by medical schools...
degrees from the University of California, San Francisco
University of California, San Francisco
The University of California, San Francisco is one of the world's leading centers of health sciences research, patient care, and education. UCSF's medical, pharmacy, dentistry, nursing, and graduate schools are among the top health science professional schools in the world...
. White obtained postgraduate training in both Internal Medicine and Anesthesiology at UC San Francisco, and has board certification in both medical specialties. In 1980, he joined the faculty at Stanford University
Stanford University
The Leland Stanford Junior University, commonly referred to as Stanford University or Stanford, is a private research university on an campus located near Palo Alto, California. It is situated in the northwestern Santa Clara Valley on the San Francisco Peninsula, approximately northwest of San...
and became a tenured Associate Professor and Chief of the Outpatient Anesthesiology Service at the University Hospital. In 1988, he accepted the position of Professor and Vice-Chair of Clinical Research in the Department of Anesthesiology at Washington University in St. Louis. He also served as the Medical Director of the Barnes Hospital
Barnes Hospital
Barnes Hospital, also known as Barnes Convalescent Home, in Cheadle, Greater Manchester, England, is a former hospital. It is located near to the A34 road and is in the middle of the complex interchange between the A34, M60 motorway and M56 motorway. Whilst the hospital was constructed in a rural...
Day Surgery Center. In 1992, he was appointed Professor and Chairman of the Department of Anesthesiology and Pain Management at the University of Texas Southwestern Medical Center
University of Texas Southwestern Medical Center
The University of Texas Southwestern Medical Center is one of the biomedical research institutions of the University of Texas System, incorporating three degree-granting institutions, four affiliated hospitals, including Parkland Memorial, the teaching hospital, and biomedical research...
. In June 2011, he retired from the Margaret Milam McDermott
Eugene McDermott
Eugene McDermott was a geophysicist and co-founder of first of Geophysical Service and later of Texas Instruments.Born in Brooklyn, New York, on February 12, 1899. He graduated from Stevens Institute of Technology in 1919 with a mechanical engineering degree.-Early career:Upon graduation,...
Distinguished Chair of Anesthesiology at UT Southwestern
University of Texas Southwestern Medical Center
The University of Texas Southwestern Medical Center is one of the biomedical research institutions of the University of Texas System, incorporating three degree-granting institutions, four affiliated hospitals, including Parkland Memorial, the teaching hospital, and biomedical research...
. He serves as a representative from the Department on the advisory board of the institution's new Center for Minimally Invasive Surgery. White has also served as a non-paid consultant to the Departments of Anesthesia at both Ohio State University
Ohio State University
The Ohio State University, commonly referred to as Ohio State, is a public research university located in Columbus, Ohio. It was originally founded in 1870 as a land-grant university and is currently the third largest university campus in the United States...
(for ambulatory surgery) and Cedars Sinai Medical Center in Los Angeles (for clinical research and continuing education programs). He has an appointment as a Director of Research at Cedars Sinai Medical Center for the Department of Anesthesiology.
White has edited nine books, including major textbooks on the subspecialties of ambulatory anesthesia and intravenous anesthesia. White has also contributed 88 chapters to textbooks edited by colleagues from around the world. In addition to publishing over 350 peer-reviewed articles, White has written 14 editorials and published over 500 scientific abstracts. Two of White's peer-reviewed publications were listed among the "Top 10" most cited articles in Anesthesiology (and he has the second most citations by any individual author in the specialty). White studies have appeared in USA Today, Washington Post, Wall Street Journal, and other media outlets. White has trained more than 65 postgraduate clinical research fellows during his academic career. He has given over 450 domestic and 250 international lectures. In addition, White has performed over 100 Visiting Professorships in the United States and abroad. White is acknowledged by his colleagues as an international leader in the fields of ambulatory anesthesia and pain management, and has been recognized in the "Best Doctors in America" and "Who's Who in North America." He was awarded the Distinguished Service Award by the Society for Ambulatory Anesthesia, and the Dannemiller Memorial Foundation's award for "Educational Excellence in Anesthesiology."
White has served on the Board of Directors of three major anesthesia organizations (namely, the Society for Ambulatory Anesthesia [SAMBA], the Society for Intravenous Anesthesia [SIVA], and the International Society for Anaesthetic Pharmacology [ISAP]). White served as the President of the SAMBA organization from 1994–95 and as President of SIVA/ISAP from 1999-2000. In addition, White has served as Chairman of the Anesthesiology Panel (1985–2000) and was a member of the Executive Committee of the United States Pharmacopoeia (1995–2000). White has been appointed to five international editorial boards and currently serves as the Section Editor for Ambulatory Anesthesia for Anesthesia & Analgesia and the Journal of Clinical Anesthesia. Finally, White has established a nonprofit foundation (the White Mountain Institute ) to advance education in the creative arts and medicine throughout the world.
White's brother, Ed White (football)
Ed White (football)
Edward Alvin White is a former American football player. After retiring from football, White has worked as a coach and artist.-Biography:He graduated from Indio High School in Indio, California...
, is a former UC Berkeley hall of fame and NFL all pro offensive lineman who played for the San Diego Chargers
San Diego Chargers
The San Diego Chargers are a professional American football team based in San Diego, California. they were members of the Western Division of the American Football Conference in the National Football League...
and Minnesota Vikings
Minnesota Vikings
The Minnesota Vikings are a professional American football team based in Minneapolis, Minnesota. The Vikings joined the National Football League as an expansion team in 1960...
.
Defense expert in Conrad Murray trial
In late October 2011, White testified as a defense expert in the trial that found Dr. Conrad MurrayTrial of Conrad Murray
The trial of Conrad Robert Murray was the American criminal trial of Michael Jackson's personal physician Conrad Murray , who was charged with involuntary manslaughter of Jackson...
guilty of the involuntary manslaughter of Michael Jackson
Michael Jackson
Michael Joseph Jackson was an American recording artist, entertainer, and businessman. Referred to as the King of Pop, or by his initials MJ, Jackson is recognized as the most successful entertainer of all time by Guinness World Records...
. White testified that the models used by the prosecution’s expert, Dr. Steven Shafer, did not show how Jackson would have responded to the drug propofol
Propofol
Propofol is a short-acting, intravenously administered hypnotic agent. Its uses include the induction and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. Propofol is also commonly used in veterinary medicine...
. White was one of the first to test propofol, and his clinical trial led to approval of the drug by the Food and Drug Administration
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...
. White also stated that Murray’s treatment of Jackson with propofol was not inappropriate because off-label drug use by doctors is not uncommon or illegal.
In his second day on the stand, White testified that Jackson probably caused his death by injecting himself with propofol while Murray was not looking. White based his conclusion on the level of propofol in Jackson’s urine during the autopsy. White also testified that Jackson had taken several tablets of Lorazepam
Lorazepam
Lorazepam is a high-potency short-to-intermediate-acting 3-hydroxy benzodiazepine drug that has all five intrinsic benzodiazepine effects: anxiolytic, amnesic, sedative/hypnotic, anticonvulsant, antiemetic and muscle relaxant...
, a sedative, which, in conjunction with the propofol, would have killed Jackson instantly.
On cross-examination, White conceded that Murray had violated the standard of medical care by administering propofol in a home setting.
At a hearing on November 16, 2011, Judge Michael Pastor found White in contempt for referring to his discussions with Murray during White's testimony, even though had been warned not to do so. He was fined $250.
Key research/publications
- Doze VA, Westphal LM, White PF, "Comparison of propofol with methohexital for outpatient anesthesia" Anesth Analg, 65:1189-95, 1986 [PMID 3490195]
- White PF, Johnston RR, Eger EI, "Determination of anesthetic requirement in rats" Anesthesiology, 40:52-7, 1974 [PMID 4810315]
- White PF, "Use of patient controlled analgesia for management of acute pain" JAMA, 259:243-7, 1988 [PMID 3275811]
- White PF, Way WL, Trevor AJ, "Ketamine--its pharmacology and therapeutic uses" Anesthesiology, 56:119-36, 1982 [PMID 6892475]
- Wagner RL, White PF, Kan PB, Rosenthal MH, Feldman D, "Inhibition of adrenal steroidogenesis by the anesthetic etomidate" N Engl J Med, 310:1415-21, 1984 [PMID 6325910]