Phosphatidylinositol 4-phosphate (PtdIns4P or PI4P) is a precursor of Phosphatidylinositol (4,5)-bisphosphate

Phosphatidylinositol (4,5)-bisphosphate

Phosphatidylinositol 4,5-bisphosphate or PtdInsP2, also known simply as PIP2, is a minor phospholipid component of cell membranes...

. PtdIns4P is prevalent in the membrane of the Golgi apparatus

Golgi apparatus

The Golgi apparatus is an organelle found in most eukaryotic cells. It was identified in 1898 by the Italian physician Camillo Golgi, after whom the Golgi apparatus is named....

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In the Golgi apparatus

Golgi apparatus

The Golgi apparatus is an organelle found in most eukaryotic cells. It was identified in 1898 by the Italian physician Camillo Golgi, after whom the Golgi apparatus is named....

, PtdIns4P binds to the GTP-binding protein ARF

ARF

-Organizations:* Advertising Research Foundation* Animal Rescue Foundation* Animal Rights Federation, an animal rights advocacy organization* Armenian Revolutionary Federation* Armtec Infrastructur Co.'s ticker symbol as of 2011...

 and to effector proteins, including four-phosphate-adaptor protein 1 and 2 (FAPP1 and FAPP2). This three molecule complex recruits proteins that need to be carried to the cell membrane

Cell membrane

The cell membrane or plasma membrane is a biological membrane that separates the interior of all cells from the outside environment. The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances in and out of cells. It basically protects the cell...

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