Pipequaline
Encyclopedia
Pipequaline is an anxiolytic
drug with a novel chemical structure
that is not closely related to other drugs of this type. It has a similar pharmacological profile to the benzodiazepine
family of drugs, but with mainly anxiolytic properties and very little sedative
, amnestic or anticonvulsant
effects, and so is classified as a nonbenzodiazepine
anxiolytic.
Pipequaline acts as a non-selective GABAA receptor partial agonist
. While its profile of anxiolytic effects without sedation would appear to have potential medical applications, pipequaline has never been developed for medical use and is currently only used in scientific research.
Anxiolytic
An anxiolytic is a drug used for the treatment of anxiety, and its related psychological and physical symptoms...
drug with a novel chemical structure
Chemical structure
A chemical structure includes molecular geometry, electronic structure and crystal structure of molecules. Molecular geometry refers to the spatial arrangement of atoms in a molecule and the chemical bonds that hold the atoms together. Molecular geometry can range from the very simple, such as...
that is not closely related to other drugs of this type. It has a similar pharmacological profile to the benzodiazepine
Benzodiazepine
A benzodiazepine is a psychoactive drug whose core chemical structure is the fusion of a benzene ring and a diazepine ring...
family of drugs, but with mainly anxiolytic properties and very little sedative
Sedative
A sedative or tranquilizer is a substance that induces sedation by reducing irritability or excitement....
, amnestic or anticonvulsant
Anticonvulsant
The anticonvulsants are a diverse group of pharmaceuticals used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder, since many seem to act as mood stabilizers, and in the treatment of neuropathic pain. The goal of an...
effects, and so is classified as a nonbenzodiazepine
Nonbenzodiazepine
The nonbenzodiazepines, also called benzodiazepine-like drugs, are a class of psychoactive drugs pharmacologically resembling the benzodiazepines, with similar benefits, side effects and risks, despite having dissimilar or entirely different chemical structures.-Classes:There are currently three...
anxiolytic.
Pipequaline acts as a non-selective GABAA receptor partial agonist
Partial agonist
Partial agonists bind and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist...
. While its profile of anxiolytic effects without sedation would appear to have potential medical applications, pipequaline has never been developed for medical use and is currently only used in scientific research.