Reductase
Encyclopedia
Examples
- 5-alpha reductase5-alpha reductase5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism. They participate in 3 metabolic pathways: bile acid biosynthesis, androgen and estrogen metabolism, and prostate cancer....
- Dihydrofolate reductaseDihydrofolate reductase- Function :Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids...
- HMG-CoA reductaseHMG-CoA reductaseHMG-CoA reductase is the rate-controlling enzyme of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids...
- Methemoglobin reductase
- Ribonucleotide reductaseRibonucleotide reductaseRibonucleotide reductase is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides. Deoxyribonucleotides in turn are used in the synthesis of DNA. The reaction catalyzed by RNR is strictly conserved in all living organisms...
- Thioredoxin reductaseThioredoxin reductaseThioredoxin Reductases are the only known enzymes to reduce thioredoxin . Two classes of thioredoxin reductase have been identified: one class in bacteria and some eukaryotes and one in animals. Both classes are flavoproteins which function as homodimers...
- E. coli nitroreductaseE. coli nitroreductaseE. coli nitroreductase is a flavoprotein found in the bacteria Escherichia coli. It catalyses the reduction of nitro groups in a wide range of substrates, to produce the corresponding hydroxylamine. Although its role in vivo is unclear, it has been identified as useful in the metabolism of a number...
- Methylenetetrahydrofolate reductaseMethylenetetrahydrofolate reductaseMethylenetetrahydrofolate reductase is an enzyme that in humans is encoded by the MTHFR gene. Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine...