SH3KBP1
Encyclopedia
SH3 domain-containing kinase-binding protein 1 is an enzyme
that in humans is encoded by the SH3KBP1 gene
.
with B-cell linker
, Grb2
, SH3GLB2
, SH3GL3
, SH3GL2
, BCAR1
, Epidermal growth factor receptor
, CBLB
, Cbl gene
, SOS1
, CRK
and PAK2
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the SH3KBP1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
SH3KBP1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with B-cell linker
B-cell linker
The B-cell linker protein is encoded by the BLNK gene and is an adaptor protein also known as SLP-65, BASH, and BCA. BLNK is expressed in B cells and macrophages and plays a large role in B cell receptor signalling, in a fashion analogous to the role its paralogue SLP-76 plays in T cell receptor...
, Grb2
Grb2
Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene....
, SH3GLB2
SH3GLB2
Endophilin-B2 is a protein that in humans is encoded by the SH3GLB2 gene.-Interactions:SH3GLB2 has been shown to interact with SH3GLB1 and SH3KBP1.-Further reading:...
, SH3GL3
SH3GL3
Endophilin-A3 is a protein that in humans is encoded by the SH3GL3 gene.-Interactions:SH3GL3 has been shown to interact with Huntingtin and SH3KBP1.-Further reading:...
, SH3GL2
SH3GL2
Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.-Interactions:SH3GL2 has been shown to interact with DNM1, Amphiphysin, ADAM9, SH3KBP1 and ADAM15.-Further reading:...
, BCAR1
BCAR1
Breast cancer anti-estrogen resistance protein 1 is a protein that in humans is encoded by the BCAR1 gene.-External links:* Info with links in the...
, Epidermal growth factor receptor
Epidermal growth factor receptor
The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family of extracellular protein ligands...
, CBLB
CBLB
E3 ubiquitin-protein ligase CBL-B is an enzyme that in humans is encoded by the CBLB gene.-Interactions:CBLB has been shown to interact with Epidermal growth factor receptor, Grb2, PIK3R1, SH3KBP1, CRKL and NEDD4.-Further reading:...
, Cbl gene
Cbl gene
Cbl is a mammalian gene encoding several proteins including E3 ubiquitin-protein ligase CBL involved in cell signalling and protein ubiquitination...
, SOS1
SOS1
Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene.Recent studies also show that mutations in Sos1 can cause Noonan syndrome and hereditary gingival fibromatosis type 1. Noonan syndrome has also been shown to be caused by mutations in KRAS and PTPN11 genes...
, CRK
CRK (gene)
Adapter molecule crk also known as proto-oncogene c-Crk or p38 is a protein that in humans is encoded by the CRK gene.- Function :...
and PAK2
PAK2
Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene.-Interactions:PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.-External links:* Info with links in the...
.