SIRT2
Encyclopedia
NAD-dependent deacetylase sirtuin-2 is an enzyme
that in humans is encoded by the SIRT2 gene
.
sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the SIRT2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Model organisms
The functions of human sirtuins have not yet been determined; however, yeastYeast
Yeasts are eukaryotic micro-organisms classified in the kingdom Fungi, with 1,500 species currently described estimated to be only 1% of all fungal species. Most reproduce asexually by mitosis, and many do so by an asymmetric division process called budding...
sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA
RDNA
rDNA may stand for:*ribosomal DNA*recombinant DNARDNA is also an acronym for*Reformed Druids of North America...
.