SUZ12
Encyclopedia
Polycomb protein SUZ12 is a protein
that in humans is encoded by the SUZ12 gene
.
SUZ12, as part of Polycomb Repressive Complex 2 (PCR2), may be involved with chromatin silencing in conjunction with HOTAIR
ncRNA, using its zinc-finger domain to bind the RNA molecule.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the SUZ12 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
SUZ12, as part of Polycomb Repressive Complex 2 (PCR2), may be involved with chromatin silencing in conjunction with HOTAIR
HOTAIR
HOTAIR is a gene at size 6,232 bp encoding 2.2 kbp long noncoding RNA molecule, which controls gene expression on chromosome 2. Its source DNA is located within a HOXC gene cluster. It is the first example of an RNA expressed on one chromosome influencing transcription on another chromosome...
ncRNA, using its zinc-finger domain to bind the RNA molecule.