Scleroderma-like reaction to taxanes
Encyclopedia
Scleroderma-like reaction to taxanes may occur in patients treated with docetaxel or paclitaxel
, characterized by an acute, diffuse, infiltrated edema of the extremities and head.
Paclitaxel
Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a U.S. National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it taxol...
, characterized by an acute, diffuse, infiltrated edema of the extremities and head.