TGF beta receptor 1
Encyclopedia
Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) is a TGF beta receptor. TGFBR1 is its human gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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Interactions

TGF beta receptor 1 has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with Mothers against decapentaplegic homolog 7
Mothers against decapentaplegic homolog 7
Mothers against decapentaplegic homolog 7 or SMAD7 is a protein that in humans is encoded by the SMAD7 gene.SMAD7 is a protein that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGFβ...

, FKBP1A
FKBP1A
Peptidyl-prolyl cis-trans isomerase FKBP1A is an enzyme that in humans is encoded by the FKBP1A gene.-Interactions:FKBP1A has been shown to interact with RYR1, Mammalian target of rapamycin, TGF beta receptor 1, GLMN, ITPR1 and KIAA1303....

, TGF beta 1
TGF beta 1
Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis...

, Caveolin 1, FNTA
FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha is an enzyme that in humans is encoded by the FNTA gene.-Interactions:FNTA has been shown to interact with TGF beta receptor 1.-Further reading:...

, PPP2R2A
PPP2R2A
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform is an enzyme that in humans is encoded by the PPP2R2A gene.-Interactions:...

, TGF beta receptor 2
TGF beta receptor 2
Transforming growth factor, beta receptor II is a TGF beta receptor. TGFBR2 is its human gene.It is a tumor suppressor gene.-Interactions:...

, Endoglin
Endoglin
Endoglin is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex.The protein consists of a homodimer of 180 kDA with disulfide links....

, Heat shock protein 90kDa alpha (cytosolic), member A1 and STRAP
STRAP
Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAP gene.-Interactions:STRAP has been shown to interact with Mothers against decapentaplegic homolog 6, TGF beta receptor 2, Mothers against decapentaplegic homolog 7, TGF beta receptor 1, Mothers...

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External links


Further reading

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