Transmembrane domain of ABC transporters
Encyclopedia
ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane domaines. Many members of the ABC transporter family have two such regions..
; ABCB10; ABCB11
; ABCB4
; ABCB5
; ABCB6
; ABCB7
; ABCB8
;
ABCB9
; ABCC1
; ABCC10
; ABCC11
; ABCC12
; ABCC13
; ABCC2
; ABCC3
;
ABCC4
; ABCC5
; ABCC6
; ABCC8
; ABCC9
; CFTR
;
TAP1
; TAP2
; TAPL;
Subfamilies
- Sulphate ABC transporter permease protein 2
- Phosphate transport system permease protein 2
- Phosphonate uptake transporter
- Nitrate transport permease
- NifC-like ABC-type porter
- Phosphate ABC transporter, permease protein PstC
- Molybdate ABC transporter, permease protein
- Nickel ABC transporter, permease subunit NikB
- Nickel ABC transporter, permease subunit NikC
- Ectoine/hydroxyectoine ABC transporter, permease protein EhuD
- Ectoine/hydroxyectoine ABC transporter, permease protein EhuC
Human proteins containing this domain
ABCB1P-glycoprotein
P-glycoprotein 1 also known as multidrug resistance protein 1 or ATP-binding cassette sub-family B member 1 or cluster of differentiation 243 is a glycoprotein that in humans is encoded by the ABCB1 gene...
; ABCB10; ABCB11
ABCB11
ATP-binding cassette, sub-family B member 11 also known as ABCB11 is a protein which in humans is encoded by the ABCB11 gene.- Function :...
; ABCB4
ABCB4
Multidrug resistance protein 3 is a protein that in humans is encoded by the ABCB4 gene. ABCB4 is associated with progressive familial intrahepatic cholestasis type 3.-External links:...
; ABCB5
ABCB5
ATP-binding cassette sub-family B member 5 also known as P-glycoprotein ABCB5 is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene...
; ABCB6
ABCB6
ATP-binding cassette sub-family B member 6, mitochondrial is a protein that in humans is encoded by the ABCB6 gene.- External links :...
; ABCB7
ABCB7
ATP-binding cassette sub-family B member 7, mitochondrial is a protein that in humans is encoded by the ABCB7 gene.-Interactions:ABCB7 has been shown to interact with Ferrochelatase.- External Links :*...
; ABCB8
ABCB8
ATP-binding cassette sub-family B member 8, mitochondrial is a protein that in humans is encoded by the ABCB8 gene.-Further reading:...
;
ABCB9
ABCB9
ATP-binding cassette sub-family B member 9 is a protein that in humans is encoded by the ABCB9 gene.- External links :...
; ABCC1
ABCC1
Multidrug resistance-associated protein 1 is a protein that in humans is encoded by the ABCC1 gene.ABCC1 clears beta-amyloid from brains of mice and can be activated by thiethylperazine.- External links :...
; ABCC10
ABCC10
Multidrug resistance-associated protein 7 is a protein that in humans is encoded by the ABCC10 gene.- External links :...
; ABCC11
ABCC11
ATP-binding cassette transporter sub-family C member 11 is a protein that in humans is encoded by the ABCC11 gene.- External links :...
; ABCC12
ABCC12
Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene.-Further reading:...
; ABCC13
ABCC13
Putative ATP-binding cassette transporter sub-family C member 13 is a protein that in humans is encoded by the ABCC13 gene.-Further reading:...
; ABCC2
ABCC2
Multidrug resistance-associated protein 2 also called canalicular multispecific organic anion transporter 1 or ATP-binding cassette sub-family C member 2 is a protein that in humans is encoded by the ABCC2 gene....
; ABCC3
ABCC3
Canalicular multispecific organic anion transporter 2 is a protein that in humans is encoded by the ABCC3 gene.- External links :...
;
ABCC4
ABCC4
ATP-binding cassette sub-family C member 4 , also known as the multidrug resistance-associated protein 4 or multi-specific organic anion transporter B , is a protein that in humans is encoded by the ABCC4 gene....
; ABCC5
ABCC5
Multidrug resistance-associated protein 5 is a protein that in humans is encoded by the ABCC5 gene.- External links :...
; ABCC6
ABCC6
Multidrug resistance-associated protein 6 also known as ATP-binding cassette sub-family C member 6 and multi-specific organic anion transporter E is a protein that in humans is encoded by the ABCC6 gene...
; ABCC8
ABCC8
ATP-binding cassette transporter sub-family C member 8 is a protein that in humans is encoded by the ABCC8 gene. ABCC8 orthologs have been identified in all mammals for which complete genome data are available.-External links:* *...
; ABCC9
ABCC9
ATP-binding cassette, sub-family C member 9 also known as sulfonylurea receptor 2 is a ATP-binding cassette transporter that in humans is encoded by the ABCC9 gene.- Function :...
; CFTR
Cystic fibrosis transmembrane conductance regulator
Cystic fibrosis transmembrane conductance regulator is a protein that in humans is encoded by the CFTR gene.CFTR is a ABC transporter-class ion channel that transports chloride and thiocyanate ions across epithelial cell membranes...
;
TAP1
TAP1
Antigen peptide transporter 1 is a protein that in humans is encoded by the TAP1 gene.-Interactions:TAP1 has been shown to interact with Tapasin and HLA-A.-Further reading:...
; TAP2
TAP2
TAP2 is a gene in humans that encodes the protein Antigen peptide transporter 2....
; TAPL;
External links
- ABC transporter integral membrane type-1 domain in PROSITEPROSITEPROSITE is a protein database. It consists of entries describing the protein families, domains and functional sites as well as amino acid patterns, signatures, and profiles in them. These are manually curated by a team of the Swiss Institute of Bioinformatics and tightly integrated into Swiss-Prot...