UBR5
Encyclopedia
E3 ubiquitin-protein ligase UBR5 is an enzyme
that in humans is encoded by the UBR5 gene
.
with TOPBP1
, CIB1
, MAPK1
and Karyopherin alpha 1.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the UBR5 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
UBR5 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with TOPBP1
TOPBP1
DNA topoisomerase 2-binding protein 1 is an enzyme that in humans is encoded by the TOPBP1 gene.-Interactions:TOPBP1 has been shown to interact with RAD9A, E2F1, Promyelocytic leukemia protein, ZBTB17 and UBR5.-Further reading:...
, CIB1
CIB1
Calcium and integrin-binding protein 1 is a protein that in humans is encoded by the CIB1 gene.-Interactions:CIB1 has been shown to interact with RAC3, PSEN2, DNA-PKcs, UBR5 and CD61.-Further reading:...
, MAPK1
MAPK1
Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.- Function :The protein encoded by this gene is a member of the MAP kinase family...
and Karyopherin alpha 1.