Wolf Szmuness
Encyclopedia
Wolf Szmuness was a Polish-born epidemiologist
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

 who emigrated to and worked in the United States. He conducted research at the New York Blood Center and, from 1973, he was director of the Center's epidemiology laboratory. He designed and conducted the trials for the first vaccine
Vaccine
A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its toxins...

 to prove effective against hepatitis B.

European beginnings

Szmuness was born in Warsaw
Warsaw
Warsaw is the capital and largest city of Poland. It is located on the Vistula River, roughly from the Baltic Sea and from the Carpathian Mountains. Its population in 2010 was estimated at 1,716,855 residents with a greater metropolitan area of 2,631,902 residents, making Warsaw the 10th most...

, Poland
Poland
Poland , officially the Republic of Poland , is a country in Central Europe bordered by Germany to the west; the Czech Republic and Slovakia to the south; Ukraine, Belarus and Lithuania to the east; and the Baltic Sea and Kaliningrad Oblast, a Russian exclave, to the north...

 on 12 March, 1919. He studied medicine
Medicine
Medicine is the science and art of healing. It encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness....

 in Italy
Italy
Italy , officially the Italian Republic languages]] under the European Charter for Regional or Minority Languages. In each of these, Italy's official name is as follows:;;;;;;;;), is a unitary parliamentary republic in South-Central Europe. To the north it borders France, Switzerland, Austria and...

, but he returned to be with his family around the Nazi German invasion of Poland in 1939. As the Germans and Soviets occupied Poland, Szmuness was separated from his family, who were later killed by the Germans. Trapped in the Communist-occupied part of Poland, Szmuness traveled eastward to escape the advancing Nazis. He asked the Soviets to let him fight the Germans but was sent to Siberia
Siberia
Siberia is an extensive region constituting almost all of Northern Asia. Comprising the central and eastern portion of the Russian Federation, it was part of the Soviet Union from its beginning, as its predecessor states, the Tsardom of Russia and the Russian Empire, conquered it during the 16th...

 as a prisoner.

Following a year of hard labour in the prison camp, Szmuness was appointed head of sanitary conditions. He later became the head epidemiologist in the local district. After release from detention in 1946, Szmuness completed his medical education at the University of Tomsk
Tomsk
Tomsk is a city and the administrative center of Tomsk Oblast, Russia, located on the Tom River. One of the oldest towns in Siberia, Tomsk celebrated its 400th anniversary in 2004...

, in central Russia, and earned a degree in epidemiology
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

 from the University of Kharkov.

Szmuness married a Russian woman, Maya, and in 1959 was allowed to return to Poland. There, he continued his education at the University of Lublin and worked as an epidemiologist in municipal and regional health departments.

Szmuness's colleague Aaron Kellner reports that the Polish authorities granted Szmuness a vacation at a rest home, where he shared a room with a Catholic
Catholic
The word catholic comes from the Greek phrase , meaning "on the whole," "according to the whole" or "in general", and is a combination of the Greek words meaning "about" and meaning "whole"...

 priest, Karol Wojtyła
Pope John Paul II
Blessed Pope John Paul II , born Karol Józef Wojtyła , reigned as Pope of the Catholic Church and Sovereign of Vatican City from 16 October 1978 until his death on 2 April 2005, at of age. His was the second-longest documented pontificate, which lasted ; only Pope Pius IX ...

, and began a longtime correspondence with him. Karol Wojtyła would later became Pope John Paul II
Pope John Paul II
Blessed Pope John Paul II , born Karol Józef Wojtyła , reigned as Pope of the Catholic Church and Sovereign of Vatican City from 16 October 1978 until his death on 2 April 2005, at of age. His was the second-longest documented pontificate, which lasted ; only Pope Pius IX ...

.

Emigration and life in the United States

In 1969, Szmuness, his wife and their daughter Helena were permitted to attend a scientific meeting in Italy
Italy
Italy , officially the Italian Republic languages]] under the European Charter for Regional or Minority Languages. In each of these, Italy's official name is as follows:;;;;;;;;), is a unitary parliamentary republic in South-Central Europe. To the north it borders France, Switzerland, Austria and...

. Upon arriving, Szmuness defected and emigrated to New York City
New York City
New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and...

 in the United States for religious and political reasons. Through the intervention of Walsh McDermott, a professor of public health at New York Hospital - Cornell Medical Center, Szmuness was hired by the New York City Blood Center. Because doctors from abroad are not usually accredited in the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

, Szmuness began as a laboratory technician, but his skills were quickly recognized, and, within two years, Szmuness headed his own lab. A separate department of epidemiology at the Center was created for him, and he also became a full professor at the Columbia University
Columbia University
Columbia University in the City of New York is a private, Ivy League university in Manhattan, New York City. Columbia is the oldest institution of higher learning in the state of New York, the fifth oldest in the United States, and one of the country's nine Colonial Colleges founded before the...

 School of Public Health. According to Aaron Kellner, President of the Center, within five years of arriving in New York, Szmuness became "an international figure in epidemiology and the field of hepatitis".

Szmuness died of lung cancer
Lung cancer
Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung. If left untreated, this growth can spread beyond the lung in a process called metastasis into nearby tissue and, eventually, into other parts of the body. Most cancers that start in lung, known as primary...

 in 1982.

Hepatitis B

Szmuness first became interested in the hepatitis B virus when his wife, Maya, was nearly killed by the liver disease caused by the virus, which she contracted through a blood transfusion. In New York, Szmuness investigated the natural history
Natural history of disease
The natural history of disease refers to a description of the uninterrupted progression of a disease in an individual from the moment of exposure to causal agents until recovery or death. Knowledge of the natural history of disease ranks alongside causal understanding in importance for disease...

 of hepatitis B. A vaccine was produced in the late 1970s, and Szmuness designed and conducted vaccine trials to determine its efficacy. Over 1000 male homosexuals participated in the trials; they were chosen as participants because they "had been found to have a risk of developing hepatitis B that is 10 times greater than that for the population in general".

AIDS Conspiracy

A discredited theory suggested that Szmuness was responsible - in some way - for the original spread of HIV in the United States by infecting gay men in New York City
New York City
New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and...

 with HIV
HIV
Human immunodeficiency virus is a lentivirus that causes acquired immunodeficiency syndrome , a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive...

. The presence of HIV in Szmuness's lab, the presence of a "Patient Zero", or a mechanism for this introduction have not been given. Scientific analysis indicates HIV first came to the United States with Haitian
Haitian
Haitian may refer to:* A person or thing of, from, or related to the country of Haiti* Haitian Creole language * Haitian cuisine* Haitian , minor character in the 2006 television series Heroes...

immigrants around 1969, many years prior to trials conducted on the Hepatitis B vaccine.
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