ATC code P01
Encyclopedia

P01AA Hydroxyquinoline derivatives

P01AA01 Broxyquinoline
Broxyquinoline
Broxyquinoline is an anti-infective.An association with exercise intolerance has been reported.-References:...

P01AA02 Clioquinol
Clioquinol
Clioquinol is an antifungal drug and antiprotozoal drug. It is neurotoxic in large doses. It is a member of a family of drugs called hydroxyquinolines which inhibit certain enzymes related to DNA replication...

P01AA04 Chlorquinaldol
Chlorquinaldol
Chlorquinaldol is an antimicrobial.-References:...

P01AA05 Tilbroquinol
Tilbroquinol
Tilbroquinol is an antiprotozoal agent....

P01AA52 Clioquinol, combinations

P01AB Nitroimidazole
Nitroimidazole
4-Nitroimidazole is an imidazole derivative that contains a nitro group.Several derivatives of nitroimidazole constitute the class of nitroimidazole antibiotics that have been used to combat anaerobic bacterial and parasitic infections. Perhaps the most common example is metronidazole . Other...

 derivatives

P01AB01 Metronidazole
Metronidazole
Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal....

P01AB02 Tinidazole
Tinidazole
Tinidazole is an anti-parasitic drug used against protozoan infections. It is widely known throughout Europe and the developing world as treatment for a variety of amoebic and parasitic infections...

P01AB03 Ornidazole
Ornidazole
Ornidazole is a drug that cures some protozoan infections. It is used by the poultry industry.It has been investigated for use in Crohn's disease after bowel resection.-References:...

P01AB04 Azanidazole
Azanidazole
Azanidazole is an nitroimidazole derivative used in gynecology for the treatment of trichomonal infections.-References:...

P01AB05 Propenidazole
Propenidazole
Propenidazole is an imidazole derivative used in gynecology....

P01AB06 Nimorazole
Nimorazole
Nimorazole is a nitroimidazole anti-infective....

P01AB07 Secnidazole
Secnidazole
Secnidazole is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae....


P01AC Dichloroacetamide
Dichloroacetamide
Dichloroacetamide is a chlorinated derivative of acetamide....

 derivatives

P01AC01 Diloxanide
P01AC02 Clefamide
Clefamide
Clefamide is an antiprotozoal agent....

P01AC03 Etofamide
Etofamide
Etofamide is an antiprotozoal drug used in the treatment of amoebiasis.Its effect against Giardia lamblia has been described as modest....

P01AC04 Teclozan
Teclozan
Teclozan is an antiprotozoal agent.It is a dichloroacetamide....


P01AR Arsenic
Arsenic
Arsenic is a chemical element with the symbol As, atomic number 33 and relative atomic mass 74.92. Arsenic occurs in many minerals, usually in conjunction with sulfur and metals, and also as a pure elemental crystal. It was first documented by Albertus Magnus in 1250.Arsenic is a metalloid...

 compounds

P01AR01 Arsthinol
Arsthinol
Arsthinol is an antiprotozoal agent. It was synthesized for the first time in 1949 by Ernst A.H. Friedheim by complexation of acetarsol with 2,3-dimercaptopropanol and has been demonstrated to be effective against amoebiasis and yaws...

P01AR02 Difetarsone
Difetarsone
Difetarsone is an antiprotozoal agent....

P01AR03 Glycobiarsol
Glycobiarsol
Glycobiarsol is an antiprotozoal agent....

P01AR53 Glycobiarsol, combinations

P01AX Other agents against amoebiasis and other protozoal diseases

P01AX01 Chiniofon
Chiniofon
Chiniofon is an antiprotozoal agent....

P01AX02 Emetine
Emetine
Emetine is a drug used as both an anti-protozoal and to induce vomiting. It is produced from the ipecac root.-Early emetine-based preparations:Early use of emetine was in the form of oral administration of the extract of ipecac root, or ipecacuanha...

P01AX04 Phanquinone
Phanquinone
Phanquinone is an antiprotozoal agent.Its bactericidal activity has also been studied....

P01AX05 Mepacrine
P01AX06 Atovaquone
Atovaquone
Atovaquone is a chemical compound that belongs to the class of naphthalenes. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of ubiquinone, with antipneumocystic activity. Its average wholesale price is about US$2.13 per standard 250 mg. tablet...

P01AX07 Trimetrexate
Trimetrexate
Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor.-Uses:It has been used with leucovorin in treating pneumocystis pneumonia.It has been investigated for use in treating leiomyosarcoma....

P01AX08 Tenonitrozole
Tenonitrozole
Tenonitrozole is an antiprotozoal agent....

P01AX09 Dehydroemetine
Dehydroemetine
Dehydroemetine is a synthetically produced antiprotozoal agent similar to emetine in its anti-amoebic properties and structure , but it produces fewer side effects...

P01AX10 Fumagillin
Fumagillin
Fumagillin is a complex biomolecule and used as an antimicrobial agent. It was isolated in 1949 from the microbial organism Aspergillus fumigatus.-In animals:...

P01AX52 Emetine, combinations

P01BA Aminoquinoline
Aminoquinoline
Aminoquinoline are derivatives of quinoline, most notable for their roles as antimalarial drugs.Depending upon the location of the amino group, they can be divided into:* 4-Aminoquinoline* 8-Aminoquinoline...

s

P01BA01 Chloroquine
Chloroquine
Chloroquine is a 4-aminoquinoline drug used in the treatment or prevention of malaria.-History:Chloroquine , N'--N,N-diethyl-pentane-1,4-diamine, was discovered in 1934 by Hans Andersag and co-workers at the Bayer laboratories who named it "Resochin". It was ignored for a decade because it was...

P01BA02 Hydroxychloroquine
Hydroxychloroquine
Hydroxychloroquine is an antimalarial drug, sold under the trade names Plaquenil,Axemal, Dolquine, and Quensyl, also used to reduce inflammation in the treatment of rheumatoid arthritis and lupus...

P01BA03 Primaquine
Primaquine
Primaquine is a medication used in the treatment of malaria and Pneumocystis pneumonia. It is a member of the 8-aminoquinoline group of drugs that includes tafenoquine and pamaquine.-Radical cure:...

P01BA06 Amodiaquine
Amodiaquine
Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent....


P01BB Biguanide
Biguanide
Biguanide can refer to a molecule, or to a class of drugs based upon this molecule. Biguanides can function as oral antihyperglycemic drugs used for diabetes mellitus or prediabetes treatment...

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P01BB01 Proguanil
Proguanil
Proguanil is a prophylactic antimalarial drug.Proguanil is effective against sporozoites.Proguanil hydrochloride is marketed as Paludrine by AstraZeneca.-Mechanism:...

P01BB02 Cycloguanil embonate
P01BB51 Proguanil, combinations

P01BD Diaminopyrimidine
Diaminopyrimidine
Diaminopyrimidines are a class of organic chemical compounds that include two amine groups on a pyrimidine ring.They include many dihydrofolate reductase inhibitor drugs .Some have been patented as anti-cancer drugs....

s

P01BD01 Pyrimethamine
Pyrimethamine
Pyrimethamine is a medication used for protozoal infections. It is commonly used as an antimalarial drug , and is also used in the treatment of Toxoplasma gondii infections in immunocompromised patients, such as HIV-positive individuals.-Mechanism of action:Pyrimethamine interferes with...

P01BD51 Pyrimethamine, combinations

P01BE Artemisinin
Artemisinin
Artemisinin , also known as Qinghaosu , and its derivatives are a group of drugs that possess the most rapid action of all current drugs against falciparum malaria. Treatments containing an artemisinin derivative are now standard treatment worldwide for falciparum malaria...

 and derivatives, plain

P01BE01 Artemisinin
Artemisinin
Artemisinin , also known as Qinghaosu , and its derivatives are a group of drugs that possess the most rapid action of all current drugs against falciparum malaria. Treatments containing an artemisinin derivative are now standard treatment worldwide for falciparum malaria...

P01BE02 Artemether
Artemether
Artemether is an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It is combined with Lumefantrine and sold by Novartis under the brand names Riamet and Co-Artem.-Chemical nature:...

P01BE03 Artesunate
Artesunate
Artesunate is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection...

P01BE04 Artemotil
Artemotil
Artemotil , is a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases. It is a semi-synthetic derivative of artemisinin, a natural product of the Chinese plant Artemisia annua...

P01BE05 Artenimol

P01BF Artemisinin and derivatives, combinations

P01BF01 Artemether and lumefantrine
Lumefantrine
Lumefantrine is an antimalarial drug. It is only used in combination with artemether. The term "co-artemether" is sometimes used to describe this combination....

P01BF02 Artesunate and mefloquine
P01BF03 Artesunate and amodiaquine
P01BF04 Artesunate, sulphamethopyrazine and pyrimethamine
P01BF05 Artenimol and piperaquine
Piperaquine
Piperaquine is an antimalarial drug, a bisquinoline first synthesised in the 1960s, and used extensively in China and Indochina as prophylaxis and treatment during the next 20 years. Usage declined in the 1980s as piperaquine-resistant strains of P. falciparum arose and artemisinin-based...

P01BF06 Artesunate and pyronaridine
Pyronaridine
Pyronaridine is an antimalarial drug. It was first synthesized in 1970 and has been in clinical use in China since the 1980s....


P01CB Antimony
Antimony
Antimony is a toxic chemical element with the symbol Sb and an atomic number of 51. A lustrous grey metalloid, it is found in nature mainly as the sulfide mineral stibnite...

 compounds

P01CB01 Meglumine antimonate
P01CB02 Sodium stibogluconate
Sodium stibogluconate
Sodium stibogluconate is a medicine used to treat leishmaniasis and is only available for administration by injection. It belongs to the class of medicines known as the pentavalent antimonials. Sodium stibogluconate is sold in the United Kingdom as Pentostam...


P01CX Other agents against leishmaniasis and trypanosomiasis

P01CX01 Pentamidine isethionate
P01CX02 Suramin sodium
Suramin
Suramin is a drug developed by Oskar Dressel and Richard Kothe of Bayer, Germany in 1916, and is still sold by Bayer under the brand name Germanin.According to the National Cancer Institute there are no active clinical trials...

P01CX03 Eflornithine
Eflornithine
Eflornithine is a drug found to be effective in the treatment of facial hirsutism as well as in African trypanosomiasis...

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