Dimepheptanol
Encyclopedia
Dimepheptanol is an opioid
analgesic
that is an analogue
of methadone
.
Dimepheptanol is a mixture of two isomer
s, α-methadol and β-methadol. These are also available separately, and this drug has three separate entries in many national and international lists of illegal drugs, which refer to the racemic mixture dimepheptanol, and the two optical isomers. Each of these isomers is itself a mixture of two isomers, and so there are in fact four isomers of dimepheptanol in total; levo-α-methadol, dextro-α-methadol, levo-β-methadol and dextro-β-methadol.
The isomer levo-α-methadol is the active metabolite of the long-acting opioid substitute drug Levomethadyl Acetate, and has been much more widely used than β-methadol or the racemic mix dimepheptanol.
Dimepheptanol has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea
and potentially serious respiratory depression which can be life-threatening.
Opioid
An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract...
analgesic
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....
that is an analogue
Analog (chemistry)
In chemistry, a structural analog , also known as chemical analog or simply analog, is a compound having a structure similar to that of another one, but differing from it in respect of a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced...
of methadone
Methadone
Methadone is a synthetic opioid, used medically as an analgesic and a maintenance anti-addictive for use in patients with opioid dependency. It was developed in Germany in 1937...
.
Dimepheptanol is a mixture of two isomer
Isomer
In chemistry, isomers are compounds with the same molecular formula but different structural formulas. Isomers do not necessarily share similar properties, unless they also have the same functional groups. There are many different classes of isomers, like stereoisomers, enantiomers, geometrical...
s, α-methadol and β-methadol. These are also available separately, and this drug has three separate entries in many national and international lists of illegal drugs, which refer to the racemic mixture dimepheptanol, and the two optical isomers. Each of these isomers is itself a mixture of two isomers, and so there are in fact four isomers of dimepheptanol in total; levo-α-methadol, dextro-α-methadol, levo-β-methadol and dextro-β-methadol.
The isomer levo-α-methadol is the active metabolite of the long-acting opioid substitute drug Levomethadyl Acetate, and has been much more widely used than β-methadol or the racemic mix dimepheptanol.
Dimepheptanol has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea
Nausea
Nausea , is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It often, but not always, precedes vomiting...
and potentially serious respiratory depression which can be life-threatening.