Eye drop
Encyclopedia
Eye drops are saline
-containing drop
s used as a route to administer
medication in the eye
. Depending on the condition being treated, they may contain steroid
s, antihistamine
s, sympathomimetics, beta receptor blocker
s, parasympathomimetics, parasympatholytic
s, prostaglandin
s, non-steroidal anti-inflammatory drug
s (NSAIDs) or topical anesthetic
s. Eye drops sometimes do not have medications in them and are only lubricating and tear
-replacing solutions.
Eye drops have less of a risk of side effects than do oral medicines, and such risk can be minimized by occluding the lacrimal punctum
, (i.e. pressing on the inner corner of the eye) for a short while after instilling drops.
help the eye's fluid
to drain better and decrease the amount of fluid made by the eye which decreases eye pressure. They are classified by their active ingredient and they include: prostaglandin analogs, beta blockers, alpha agonists, and carbonic anhydrase inhibitors
. There are also combination drugs available for those patients who require more than one type of medication.
strategies. One can find bicarbonate ions, hypotonicity, viscosity
, and non-preserved types. They all act differently, therefore, one should try different artificial tears to find the one that best works.
widen to maximum, to let an optician
have the best view inside the eyeball behind the iris. Afterwards in sunny weather they can cause dazzling and photophobia
until the effect of the mydriatic has worn off.
, fever
, easy bleeding
or bruising when using drops with chloramphenicol
. Also, one should be aware of symptoms of an allergic reaction, such as: rash
, itching, swelling
, dizziness
, and trouble breathing.
Prostaglandin analogs may cause changes in iris
color and eyelid
skin, growth of eyelashes, stinging, blurred vision
, eye redness, itching, and burning. Beta blockers' side effects include low blood pressure, reduced pulse rate, fatigue, shortness of breath, and in rare occasions, reduced libido
and depression
. Alpha agonists can cause burning or stinging, fatigue, headache
, drowsiness, dry mouth
and nose
, and also they have a higher likelihood of allergic reaction. Carbonic anhydrase inhibitors may cause stinging, burning, and eye discomfort.
Lubricant eye drops may cause some side effects and one should consult a doctor if pain in the eye or changes in vision occur. Furthermore, when redness occurs but lasts more than 3 days, one should immediately consult a doctor.
Saline (medicine)
In medicine, saline is a general term referring to a sterile solution of sodium chloride in water but is only sterile when it is to be placed intravenously, otherwise, a saline solution is a salt water solution...
-containing drop
Drop (liquid)
A drop or droplet is a small column of liquid, bounded completely or almost completely by free surfaces. A drop may form when liquid accumulates at the lower end of a tube or other surface boundary, producing a hanging drop called a pendant drop...
s used as a route to administer
Route of administration
A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body.-Classification:Routes of administration are usually classified by application location...
medication in the eye
Human eye
The human eye is an organ which reacts to light for several purposes. As a conscious sense organ, the eye allows vision. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth...
. Depending on the condition being treated, they may contain steroid
Steroid
A steroid is a type of organic compound that contains a characteristic arrangement of four cycloalkane rings that are joined to each other. Examples of steroids include the dietary fat cholesterol, the sex hormones estradiol and testosterone, and the anti-inflammatory drug dexamethasone.The core...
s, antihistamine
Antihistamine
An H1 antagonist is a histamine antagonist of the H1 receptor that serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions...
s, sympathomimetics, beta receptor blocker
Beta blocker
Beta blockers or beta-adrenergic blocking agents, beta-adrenergic antagonists, beta-adrenoreceptor antagonists or beta antagonists, are a class of drugs used for various indications. They are particularly for the management of cardiac arrhythmias, cardioprotection after myocardial infarction ,...
s, parasympathomimetics, parasympatholytic
Parasympatholytic
A parasympatholytic agent is a substance or activity that reduces the activity of the parasympathetic nervous system. A parasympatholytic agent is a substance or activity that reduces the activity of the parasympathetic nervous system. A parasympatholytic agent is a substance or activity that...
s, prostaglandin
Prostaglandin
A prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring....
s, non-steroidal anti-inflammatory drug
Non-steroidal anti-inflammatory drug
Nonsteroidal anti-inflammatory drugs, usually abbreviated to NSAIDs or NAIDs, but also referred to as nonsteroidal anti-inflammatory agents/analgesics or nonsteroidal Anti-inflammatory medicines , are drugs with analgesic and antipyretic effects and which have, in higher doses, anti-inflammatory...
s (NSAIDs) or topical anesthetic
Topical anesthetic
A topical anesthetic is a local anesthetic that is used to numb the surface of a body part. They can be used to numb any area of the skin as well as the front of the eyeball, the inside of the nose, ear or throat, the anus and the genital area. Topical anesthetics are available in creams,...
s. Eye drops sometimes do not have medications in them and are only lubricating and tear
Tears
Tears are secretions that clean and lubricate the eyes. Lacrimation or lachrymation is the production or shedding of tears....
-replacing solutions.
Eye drops have less of a risk of side effects than do oral medicines, and such risk can be minimized by occluding the lacrimal punctum
Lacrimal punctum
The lacrimal canaliculi, one in each eyelid, commence at minute orifices, termed puncta lacrimalia , on the summits of the papillae lacrimales, seen on the margins of the lids at the lateral extremity of the lacus lacrimalis...
, (i.e. pressing on the inner corner of the eye) for a short while after instilling drops.
Types and uses
Different pharmacological classes of eye drops can be recognized by patients by their different colored tops. For instance the tops to dilating drops are a different color than anti-allergy drops.Rinse eye drops
These eye drops contains normal saline with no excipients and are used primarily for eye rinsing.Steroid and antibiotic eye drops
Steroid and antibiotic eye drops are used to treat eye infections. They also have prophylactic properties and are used to prevent infections after eye surgeries. They should be used for the full time prescribed without interruptions. The infection may relapse if the use of the medication is stopped.Glaucoma eye drops
Eye drops used in managing glaucomaGlaucoma
Glaucoma is an eye disorder in which the optic nerve suffers damage, permanently damaging vision in the affected eye and progressing to complete blindness if untreated. It is often, but not always, associated with increased pressure of the fluid in the eye...
help the eye's fluid
Fluid
In physics, a fluid is a substance that continually deforms under an applied shear stress. Fluids are a subset of the phases of matter and include liquids, gases, plasmas and, to some extent, plastic solids....
to drain better and decrease the amount of fluid made by the eye which decreases eye pressure. They are classified by their active ingredient and they include: prostaglandin analogs, beta blockers, alpha agonists, and carbonic anhydrase inhibitors
Carbonic anhydrase inhibitors
Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. Their clinical use has been established as antiglaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, neurological disorders, or...
. There are also combination drugs available for those patients who require more than one type of medication.
Dry eye treatment
There is a wide variety of artificial tear eye drops that provide different surface healingHealing
Physiological healing is the restoration of damaged living tissue, organs and biological system to normal function. It is the process by which the cells in the body regenerate and repair to reduce the size of a damaged or necrotic area....
strategies. One can find bicarbonate ions, hypotonicity, viscosity
Viscosity
Viscosity is a measure of the resistance of a fluid which is being deformed by either shear or tensile stress. In everyday terms , viscosity is "thickness" or "internal friction". Thus, water is "thin", having a lower viscosity, while honey is "thick", having a higher viscosity...
, and non-preserved types. They all act differently, therefore, one should try different artificial tears to find the one that best works.
Allergy eye relief eye drops
Some eye drops may contain histamine antagonists or non-steroidal anti-inflammatory drugs, which suppress the optical mast cell responses to allergens including (but not limited to) aerosolized dust particles.Pink eye or conjunctivitis eye drops
Antibiotic eye drops are prescribed when conjunctivitis is caused by bacteria but not when it is caused by a virus. In the case of allergic conjunctivitis, artificial tears can help dilute irritating allergens present in the tear film.Mydriatic eye drops
These make the eye's pupilPupil
The pupil is a hole located in the center of the iris of the eye that allows light to enter the retina. It appears black because most of the light entering the pupil is absorbed by the tissues inside the eye. In humans the pupil is round, but other species, such as some cats, have slit pupils. In...
widen to maximum, to let an optician
Optician
An optician is a person who is trained to fill prescriptions for eye correction in the field of medicine, also known as a dispensing optician or optician, dispensing...
have the best view inside the eyeball behind the iris. Afterwards in sunny weather they can cause dazzling and photophobia
Photophobia
Photophobia is a symptom of abnormal intolerance to visual perception of light. As a medical symptom photophobia is not a morbid fear or phobia, but an experience of discomfort or pain to the eyes due to light exposure or by presence of actual physical photosensitivity of the eyes, though the term...
until the effect of the mydriatic has worn off.
Side effects
Steroid and antibiotic eye drops may cause stinging for one or two minutes when first used and if stinging continues, medical advice should be sought. Also, one should tell their doctor if vision changes occur or if they experience persistent sore throatSore throat
A sore throat or throat pain is a common physical symptom usually caused by acute pharyngitis, or throat inflammation, though it also occurs in a number of other situations, such as post trauma and in diphtheria. It can cause mild to extreme pain....
, fever
Fever
Fever is a common medical sign characterized by an elevation of temperature above the normal range of due to an increase in the body temperature regulatory set-point. This increase in set-point triggers increased muscle tone and shivering.As a person's temperature increases, there is, in...
, easy bleeding
Bleeding
Bleeding, technically known as hemorrhaging or haemorrhaging is the loss of blood or blood escape from the circulatory system...
or bruising when using drops with chloramphenicol
Chloramphenicol
Chloramphenicol is a bacteriostatic antimicrobial that became available in 1949. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracyclines, and as it is both cheap and easy to manufacture it is frequently found as a drug of choice in the third world.Chloramphenicol is...
. Also, one should be aware of symptoms of an allergic reaction, such as: rash
Rash
A rash is a change of the skin which affects its color, appearance or texture. A rash may be localized in one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, chapped, dry, cracked or blistered, swell and may be painful. The causes, and...
, itching, swelling
Swelling
Swelling , is the enlargement of tissue.Swelling can also mean:*Die swell, the increase of volume of material due to absorption of a solvent, common for plastic polymers*Neutron-induced swelling caused by neutron radiation....
, dizziness
Dizziness
Dizziness refers to an impairment in spatial perception and stability. The term is somewhat imprecise. It can be used to mean vertigo, presyncope, disequilibrium, or a non-specific feeling such as giddiness or foolishness....
, and trouble breathing.
Prostaglandin analogs may cause changes in iris
Iris (anatomy)
The iris is a thin, circular structure in the eye, responsible for controlling the diameter and size of the pupils and thus the amount of light reaching the retina. "Eye color" is the color of the iris, which can be green, blue, or brown. In some cases it can be hazel , grey, violet, or even pink...
color and eyelid
Eyelid
An eyelid is a thin fold of skin that covers and protects an eye. With the exception of the prepuce and the labia minora, it has the thinnest skin of the whole body. The levator palpebrae superioris muscle retracts the eyelid to "open" the eye. This can be either voluntarily or involuntarily...
skin, growth of eyelashes, stinging, blurred vision
Blurred vision
-Causes:There are many causes of blurred vision:* Use of atropine or other anticholinergics* Presbyopia -- Difficulty focusing on objects that are close. The elderly are common victims....
, eye redness, itching, and burning. Beta blockers' side effects include low blood pressure, reduced pulse rate, fatigue, shortness of breath, and in rare occasions, reduced libido
Libido
Libido refers to a person's sex drive or desire for sexual activity. The desire for sex is an aspect of a person's sexuality, but varies enormously from one person to another, and it also varies depending on circumstances at a particular time. A person who has extremely frequent or a suddenly...
and depression
Depression (mood)
Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behaviour, feelings and physical well-being. Depressed people may feel sad, anxious, empty, hopeless, helpless, worthless, guilty, irritable, or restless...
. Alpha agonists can cause burning or stinging, fatigue, headache
Headache
A headache or cephalalgia is pain anywhere in the region of the head or neck. It can be a symptom of a number of different conditions of the head and neck. The brain tissue itself is not sensitive to pain because it lacks pain receptors. Rather, the pain is caused by disturbance of the...
, drowsiness, dry mouth
Mouth
The mouth is the first portion of the alimentary canal that receives food andsaliva. The oral mucosa is the mucous membrane epithelium lining the inside of the mouth....
and nose
Human nose
The visible part of the human nose is the protruding part of the face that bears the nostrils. The shape of the nose is determined by the ethmoid bone and the nasal septum, which consists mostly of cartilage and which separates the nostrils...
, and also they have a higher likelihood of allergic reaction. Carbonic anhydrase inhibitors may cause stinging, burning, and eye discomfort.
Lubricant eye drops may cause some side effects and one should consult a doctor if pain in the eye or changes in vision occur. Furthermore, when redness occurs but lasts more than 3 days, one should immediately consult a doctor.
See also
- Carboxymethyl celluloseCarboxymethyl celluloseCarboxymethyl cellulose or cellulose gum is a cellulose derivative with carboxymethyl groups bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone...
- Tetrahydrozoline hydrochloride
- MydriasisMydriasisMydriasis is a dilation of the pupil due to disease, trauma or the use of drugs. Normally, the pupil dilates in the dark and constricts in the light to respectively improve vividity at night and to protect the retina from sunlight damage during the day...
- Refractive errorRefractive errorA refractive error, or refraction error, is an error in the focusing of light by the eye and a frequent reason for reduced visual acuity.-Classification:...
- VisineVisineVisine is a brand of eye drops produced by Johnson & Johnson. Johnson & Johnson acquired Visine, along with Pfizer's entire consumer healthcare portfolio, in December 2006.-Visine Original:...
- Artificial tears