HLA-B54
Encyclopedia
| Alleles | B*5401 | |
| Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... ) |
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| Symbol(s) Human Genome Organisation The Human Genome Organisation is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world... |
HLA-B | |
| EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
B*5401 | |
| Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map... |
chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells... 6p21.31 |
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HLA-B54 (B54) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
. B54 is a split antigen from the B22
HLA-B22
HLA-B22 is an HLA - B serotype. B22 is a broad antigen serotype that recognizes the B54, B55, and B56 split antigen serotypes....
broad antigen, sister serotypes are B55
HLA-B55
HLA-B55 is an HLA-B serotype. B55 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products. -Serotype:...
and B56
HLA-B56
HLA-B56 is an HLA-B serotype. B56 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B55. The serotype identifies the more common HLA-B*56 gene products. -Serotype:...
. The serotype identifies the more common HLA-B*55 gene products.
Serotype
| B*54 | B54 | B22 | Sample |
| allele | % | % | size (N) |
| 5401 | 67 | 3 | 631 |
Allele distribution
| freq | ||
| ref. | Population | (%) |
| USA Hawaii Okinawa | 10.6 | |
| Japan Central | 7.7 | |
| South Korea (3) | 5.9 | |
| China Guangzhou | 4.5 | |
| Thailand (3) | 4.1 | |
| China Inner Mongolia | 3.4 | |
| China North Han | 3.3 | |
| China Beijing Shijiazhuang Tianjian Han | 3.0 | |
| China South Han | 2.5 | |
| Russia Tuva pop 2 | 2.2 | |
| China Guangxi Maonan | 1.9 | |
| Thailand | 1.8 | |
| Taiwan Thao | 1.7 | |
| China Tibet Autonomous Region Tibetans | 1.3 |