HLA-B56
Encyclopedia
Alleles B*5601, *5602, *5603, *5604
Structure (See HLA-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...

)
Symbol(s)
Human Genome Organisation
The Human Genome Organisation is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world...

HLA-B
EBI-HLA
European Bioinformatics Institute
The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory...

B*5601
B*5602
B*5603
B*5604
Locus
Locus (genetics)
In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map...

chr.6
Chromosome 6 (human)
Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells...

 6p21.31


HLA-B56 (B56) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...

-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...

 serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...

. B56 is a split antigen from the B22
HLA-B22
HLA-B22 is an HLA - B serotype. B22 is a broad antigen serotype that recognizes the B54, B55, and B56 split antigen serotypes....

 broad antigen, sister serotypes are B54
HLA-B54
HLA-B54 is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56. The serotype identifies the more common HLA-B*55 gene products.-Serotype:-Allele distribution:...

 and B55
HLA-B55
HLA-B55 is an HLA-B serotype. B55 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products. -Serotype:...

. The serotype identifies the more common HLA-B*56 gene products. (For terminology help see: HLA-serotype tutorial)

Serotype

B56 and B22 serotype recognition of Some HLA B*56 allele-group gene products
B*56 B56 B22 Sample
allele % % size (N)
5601 72 5 671
5603 46 8 13
5604 73 11

Allele distribution

HLA B*5601 frequencies
freq
ref. Population (%)
Australian Aborigine Kimberly 35.5
Papua New Guinea Madang 34.6
Papua New Guinea New Britain Rabaul 31.6
Taiwan Ami 20.4
New Caledonia 19.2
Australian Aborigine Groote Eylandt 18.0
Australian Aborigine Cape York Peninsula 16.5
Australian Aborigine Yuendumu 11.4
China Yunnan Lisu 9.4
China Yunnan Nu 3.8
Senegal Niokholo Mandenka 2.7
Sudanese 2.5
American Samoa 2.0
China Guangxi Maonan 1.9
Taiwan Hakka 1.8
Thailand 1.8
Finland 1.7
Georgia Tibilisi Kurds 1.7
India Andhra Pradesh Golla 1.4
Croatia 1.3
Japan (5) 1.3
South Africa Natal Tamil 1.0
Taiwan Rukai 1.0
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