HLA-B55
Encyclopedia
Alleles B*5501, B*5502
Structure (See HLA-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...

)
Symbol(s)
Human Genome Organisation
The Human Genome Organisation is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world...

HLA-B
EBI-HLA
European Bioinformatics Institute
The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory...

B*5501
B*5502
Locus
Locus (genetics)
In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map...

chr.6
Chromosome 6 (human)
Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells...

 6p21.31


HLA-B55 (B55) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...

-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...

 serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...

. B55 is a split antigen from the B22
HLA-B22
HLA-B22 is an HLA - B serotype. B22 is a broad antigen serotype that recognizes the B54, B55, and B56 split antigen serotypes....

 broad antigen, sister serotypes are B54
HLA-B54
HLA-B54 is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56. The serotype identifies the more common HLA-B*55 gene products.-Serotype:-Allele distribution:...

 and B56
HLA-B56
HLA-B56 is an HLA-B serotype. B56 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B55. The serotype identifies the more common HLA-B*56 gene products. -Serotype:...

. The serotype identifies the more common HLA-B*55 gene products. (For terminology help see: HLA-serotype tutorial)

Serotype

B55 and B22 serotype recognition of some HLA B*55 allele-group gene products
B*55 B55 B22 Sample
allele % % size (N)
5501 92 5 453
5502 84 2 309

Allele distribution

HLA B*5501 frequencies
freq
ref. Population (%)
India New Delhi 3.8
Singapore Chinese Han 3.5
Spain Eastern Andalusia Gipsy 3.5
Georgia Tibilisi Kurds 3.4
India North Delhi 3.3
France South East 3.1
Israel Arab Druse 3.0
India North Hindus 2.9
Georgia Tibilisi Georgians 2.8
Russia Tuva (2) 2.8
Georgia Svaneti Svans 2.5
Iran Baloch 2.5
Singapore Thai 2.5
Sudanese 2.5
Mexico Mestizos 2.4
Spain Eastern Andalusia 2.4
Ireland South 2.0
Azores Central Islands 1.8
Bulgaria 1.8
Israel Ashkenazi and Non Ashkenazi Jews 1.8
Oman 1.7
Tunisia Tunis 1.7
India Andhra Pradesh Golla 1.4
China Tibet 1.3
Uganda Kampala 1.2
Finland 1.1
Portugal North 1.1
Portugal Centre 1.0
Singapore Riau Malay 1.0
B*5502
Taiwan Taroko 14.5
American Samoa 12.0
China Guangxi Maonan 6.0
Japan Ainu Hokkaido 5.0
China Tibet Autonomous Region Tibetans 4.7
Singapore Chinese 3.0
China Beijing Shijiazhuang Tianjian Han 2.9
China North Han 2.9
South Korea (3) 2.7
Hong Kong Chinese 2.2
Japan (5) 2.2
Taiwan Ami 2.0
Thailand (3) 2.0
New Caledonia 1.0
Philippines Ivatan 1.0
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