Heparin-binding EGF-like growth factor
Encyclopedia
Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins. It has been shown to play a role in wound healing
, cardiac hypertrophy and heart development
and function.
with NRD1
, Zinc finger and BTB domain-containing protein 16
and BAG1
.
Wound healing
Wound healing, or cicatrisation, is an intricate process in which the skin repairs itself after injury. In normal skin, the epidermis and dermis exists in a steady-state equilibrium, forming a protective barrier against the external environment...
, cardiac hypertrophy and heart development
Heart development
The heart is the first functional organ in a vertebrate embryo. There are 5 stages to heart development.- Specification of cardiac precursor cells :...
and function.
Interactions
Heparin-binding EGF-like growth factor has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with NRD1
NRD1
Nardilysin is a protein that in humans is encoded by the NRD1 gene.-Interactions:NRD1 has been shown to interact with Heparin-binding EGF-like growth factor.-Further reading:...
, Zinc finger and BTB domain-containing protein 16
Zinc finger and BTB domain-containing protein 16
Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.-Function:This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the...
and BAG1
BAG1
BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's...
.