Johann Joseph Scherer
Encyclopedia
Johann Joseph Scherer was a German physician and chemist
who was born in Aschaffenburg
.
In 1836 he graduated from the University of Würzburg
, where he studied medicine, chemistry
, geology
and mineralogy
. From 1836 to 1838 he practiced medicine in Wipfeld
, and afterwards continued in studies in chemistry at the University of Munich. In 1840 he worked in the laboratory of Justus Liebig (1803-1873) at Giessen, and in 1842 returned to Würzburg
as a professor of organic chemistry
. During his career at Würzburg, he held the title of professor in the departments of general, inorganic
, and pharmacological chemistry
, and also attained the directorship of the Medical Institute for Chemistry and Hygiene
.
Scherer was a pioneer of clinical chemistry, and is remembered for applying his knowledge of chemistry to problems in the field of medicine. He made contributions in the study of urine
and blood in pathological conditions, and in 1843 and 1851 demonstrated the presence of lactic acid
in human blood under conditions such as hemorrhagic and septic shock
. Scherer is also credited with the discoveries of inositol
and the purine
derivative known as hypoxanthine
.
Beginning in 1852, with Rudolf Virchow
(1821-1902) and Gottfried Eisenmann (1795-1867) he was co-editor of Karl Friedrich Canstatt
’s (1807-1850) annual reports, Jahresbericht über die Leistungen und Fortschritte der gesammten Medicin. One of his better known publications was the 1843 book Chemische und Mikroskopische Untersuchungen zur Pathologie angestellt an den Kliniken des Julius-Hospitales zu Würzburg (Chemical and Microscopic Investigations of Pathology performed at the Julius Hospital Clinic at Würzburg).
Chemist
A chemist is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties such as density and acidity. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms...
who was born in Aschaffenburg
Aschaffenburg
Aschaffenburg is a city in northwest Bavaria, Germany. The town of Aschaffenburg is not considered part of the district of Aschaffenburg, but is the administrative seat.Aschaffenburg is known as the Tor zum Spessart or "gate to the Spessart"...
.
In 1836 he graduated from the University of Würzburg
University of Würzburg
The University of Würzburg is a university in Würzburg, Germany, founded in 1402. The university is a member of the distinguished Coimbra Group.-Name:...
, where he studied medicine, chemistry
Chemistry
Chemistry is the science of matter, especially its chemical reactions, but also its composition, structure and properties. Chemistry is concerned with atoms and their interactions with other atoms, and particularly with the properties of chemical bonds....
, geology
Geology
Geology is the science comprising the study of solid Earth, the rocks of which it is composed, and the processes by which it evolves. Geology gives insight into the history of the Earth, as it provides the primary evidence for plate tectonics, the evolutionary history of life, and past climates...
and mineralogy
Mineralogy
Mineralogy is the study of chemistry, crystal structure, and physical properties of minerals. Specific studies within mineralogy include the processes of mineral origin and formation, classification of minerals, their geographical distribution, as well as their utilization.-History:Early writing...
. From 1836 to 1838 he practiced medicine in Wipfeld
Wipfeld
Wipfeld is a municipality in the district of Schweinfurt in Bavaria, Germany.-Twin towns:Wipfeld is twinned with: Follina, Italy...
, and afterwards continued in studies in chemistry at the University of Munich. In 1840 he worked in the laboratory of Justus Liebig (1803-1873) at Giessen, and in 1842 returned to Würzburg
Würzburg
Würzburg is a city in the region of Franconia which lies in the northern tip of Bavaria, Germany. Located at the Main River, it is the capital of the Regierungsbezirk Lower Franconia. The regional dialect is Franconian....
as a professor of organic chemistry
Organic chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, composition, reactions, and preparation of carbon-based compounds, hydrocarbons, and their derivatives...
. During his career at Würzburg, he held the title of professor in the departments of general, inorganic
Inorganic chemistry
Inorganic chemistry is the branch of chemistry concerned with the properties and behavior of inorganic compounds. This field covers all chemical compounds except the myriad organic compounds , which are the subjects of organic chemistry...
, and pharmacological chemistry
Pharmacology
Pharmacology is the branch of medicine and biology concerned with the study of drug action. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function...
, and also attained the directorship of the Medical Institute for Chemistry and Hygiene
Hygiene
Hygiene refers to the set of practices perceived by a community to be associated with the preservation of health and healthy living. While in modern medical sciences there is a set of standards of hygiene recommended for different situations, what is considered hygienic or not can vary between...
.
Scherer was a pioneer of clinical chemistry, and is remembered for applying his knowledge of chemistry to problems in the field of medicine. He made contributions in the study of urine
Urine
Urine is a typically sterile liquid by-product of the body that is secreted by the kidneys through a process called urination and excreted through the urethra. Cellular metabolism generates numerous by-products, many rich in nitrogen, that require elimination from the bloodstream...
and blood in pathological conditions, and in 1843 and 1851 demonstrated the presence of lactic acid
Lactic acid
Lactic acid, also known as milk acid, is a chemical compound that plays a role in various biochemical processes and was first isolated in 1780 by the Swedish chemist Carl Wilhelm Scheele. Lactic acid is a carboxylic acid with the chemical formula C3H6O3...
in human blood under conditions such as hemorrhagic and septic shock
Septic shock
Septic shock is a medical emergency caused by decreased tissue perfusion and oxygen delivery as a result of severe infection and sepsis, though the microbe may be systemic or localized to a particular site. It can cause multiple organ dysfunction syndrome and death...
. Scherer is also credited with the discoveries of inositol
Inositol
Inositol or cyclohexane-1,2,3,4,5,6-hexol is a chemical compound with formula 6126 or 6, a sixfold alcohol of cyclohexane. It exists in nine possible stereoisomers, of which the most prominent form, widely occurring in nature, is cis-1,2,3,5-trans-4,6-cyclohexanehexol, or myo-inositol...
and the purine
Purine
A purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Purines, including substituted purines and their tautomers, are the most widely distributed kind of nitrogen-containing heterocycle in nature....
derivative known as hypoxanthine
Hypoxanthine
Hypoxanthine is a naturally occurring purine derivative. It is occasionally found as a constituent of nucleic acids where it is present in the anticodon of tRNA in the form of its nucleoside inosine. It has a tautomer known as 6-Hydroxypurine. Hypoxanthine is a necessary additive in certain cell,...
.
Beginning in 1852, with Rudolf Virchow
Rudolf Virchow
Rudolph Carl Virchow was a German doctor, anthropologist, pathologist, prehistorian, biologist and politician, known for his advancement of public health...
(1821-1902) and Gottfried Eisenmann (1795-1867) he was co-editor of Karl Friedrich Canstatt
Karl Friedrich Canstatt
Karl Friedrich Canstatt was a German physician and medical author. He was one of the pioneers of the modern school of medicine in Germany, and numbered Professor Rudolf Virchow among his pupils. Canstatt studied at the University of Vienna and later under Schönlein at Würzburg, where in 1831 he...
’s (1807-1850) annual reports, Jahresbericht über die Leistungen und Fortschritte der gesammten Medicin. One of his better known publications was the 1843 book Chemische und Mikroskopische Untersuchungen zur Pathologie angestellt an den Kliniken des Julius-Hospitales zu Würzburg (Chemical and Microscopic Investigations of Pathology performed at the Julius Hospital Clinic at Würzburg).