Criteria

• The security U.S. listing must be exclusively on the NASDAQ National Market (unless the security was dually listed on another U.S. market prior to January 1, 2004 and has continuously maintained such listing).
• The issuer of the security must be classified according to the Industry Classification Benchmark as either Biotechnology or Pharmaceuticals.
• The security may not be issued by an issuer currently in bankruptcy proceedings.
• The security must have a market capitalization of at least $200 million.
• The security must have an average daily trading volume of at least 100,000 shares.
• The issuer of the security may not have entered into a definitive agreement or other arrangement which would likely result in the security no longer being Index.
• The issuer of the security may not have annual financial statements with an audit opinion that is currently withdrawn.
• The issuer of the security must have "seasoned" on NASDAQ or another recognized market for at least 6 months; in the case of spin-offs, the operating history of the spin-off will be considered.

Components

• Acorda Therapeutics
  Acorda Therapeutics
  Acorda Therapeutics is a biotechnology company based in Hawthorne, New York. Acorda Therapeutics develops drugs to improve therapies that improve neurological function in people with multiple sclerosis, spinal cord injury and other disorders of the central nervous system...
  
   Inc.
• Adolor Corporation
  Adolor Corporation
  Adolor Corporation is a biopharmaceutical company specializing in the discovery, development and commercialization of prescription pain management products....
  
   
• Affymetrix
  Affymetrix
  Affymetrix is a company that manufactures DNA microarrays; it is based in Santa Clara, California, United States. The company was founded by Dr. Stephen Fodor in 1992. It began as a unit in Affymax N.V...
  
   Inc.
• Akorn Inc.
• Albany Molecular Research Inc.
• Alexion Pharmaceuticals
  Alexion Pharmaceuticals
  Alexion Pharmaceuticals is the original developer and distributor of Soliris, a drug used in treating the ultra-rare disorders Hemolytic-uremic syndrome and Paroxysmal nocturnal hemoglobinuria . In a recent study Soliris was noted for its effectiveness in altering the natural course of PNH...
  
   Inc.
• Alexza Pharmaceuticals Inc.
• Alkermes Inc.
• Allos Therapeutics Inc.
• Alnylam Pharmaceuticals Inc.
• AMAG Pharmaceuticals Inc.
• Amgen
  Amgen
  Amgen Inc. is an international biotechnology company headquartered in Thousand Oaks, California. Located in the Conejo Valley, Amgen is the world's largest independent biotech firm. The company employs approximately 17,000 staff members. Its products include Epogen, Aranesp, Enbrel, Kineret,...
  
   Inc.
• Amylin Pharmaceuticals
  Amylin Pharmaceuticals
  Amylin Pharmaceuticals is a biopharmaceutical company based in San Diego, CA, that was founded in 1987. The company is engaged in the discovery, development and commercialization of drug candidates for the treatment of diabetes, obesity and other diseases. Currently, Amylin produces two drugs,...
  
   Inc.
• Anthera Pharmaceuticals
  Anthera Pharmaceuticals
  Anthera Pharmaceuticals, Inc. is a pharmaceutical company that specializes in developing treatments for serious cardiovascular and autoimmune diseases...
  
   Inc.
• Arena Pharmaceuticals
  Arena Pharmaceuticals
  Arena Pharmaceuticals, Inc. is a biopharmaceutical company located in San Diego, California. The company is developing oral medications that target G-protein-coupled receptors. Currently none of the drugs is approved by the U.S...
  
   Inc.
• ARIAD Pharmaceuticals
  ARIAD Pharmaceuticals
  ARIAD Pharmaceuticals, Inc. is a small pharmaceutical company working on cancer drugs. The company is located in Cambridge, Massachusetts. It was established in 1991 by Larry Bock, David Blech and Dr. Harvery Berger...
  
   Inc.
• ArQule Inc.
• Array BioPharma Inc.
• Auxilium Pharmaceuticals Inc.
• BioCryst Pharmaceuticals
  BioCryst Pharmaceuticals
  BioCryst Pharmaceuticals, Inc. is a pharmaceutical company headquartered in Birmingham, Alabama. The company focuses on cancer, autoimmune diseases, and viral infections...
  
   Inc.
• Biodel Inc.
• Biogen Idec
  Biogen Idec
  Biogen Idec, Inc. is a biotechnology company specializing in drugs for neurological disorders, autoimmune disorders and cancer. The company was formed in 2003 by the merger of Cambridge, Massachusetts-based Biogen Inc. and San Diego, California-based IDEC Pharmaceuticals...
  
   Inc.
• BioMarin Pharmaceutical
  BioMarin Pharmaceutical
  BioMarin Pharmaceutical Inc. is a biotechnology firm based in Novato, California. It has offices and facilities in the US, South America, Asia and Europe. BioMarin's core business and research is in enzyme replacement therapies...
  
   Inc.
• BioMimetic Therapeutics Inc.
• Bionovo
  Bionovo
  Bionovo is an American biotechnology company focused on the discovery and development of botanically derived treatments for women's health and cancer based in Emeryville, California. The company currently has two drug candidates in U.S...
  
   Inc.
• BMP Sunstone Corporation
• Cadence Pharmaceuticals Inc.
• Cardiome Pharma Corporation
• Celera Corporation 
• Celgene
  Celgene
  Celgene Corporation is a manufacturer of drug therapies for cancer and inflammatory disorders. It is incorporated in Delaware and headquartered in Summit, New Jersey...
  
   Corporation
• Cephalon
  Cephalon
  Cephalon, Inc. is a U.S. biopharmaceutical company co-founded in 1987 by Dr. Frank Baldino, Jr., a pharmacologist and former scientist with the DuPont Company, who served as the company's chairman and chief executive officer until his death in December 2010...
  
   Inc.
• Columbia Laboratories Inc.
• Crucell
  Crucell
  Crucell is a biotechnology company specializing in vaccines and antibodies. The firm, a subsidiary of Johnson & Johnson, is headquartered in Leiden, Netherlands...
  
   NV
• Cubist Pharmaceuticals
  Cubist Pharmaceuticals
  Cubist Pharmaceuticals is a biopharmaceutical company with activities spanning from research and development to commercialization of pharmaceutical products. Its main products address unmet medical needs in acute care, specifically pathogens like MRSA...
  
   Inc.
• Cypress Bioscience Inc.
• Cytokinetics Incorporated
• Dendreon
  Dendreon
  Dendreon is a Seattle based biotechnology company. Its lead product, Provenge , is an immunotherapy for prostate cancer...
  
   Corporation
• DepoMed Inc.
• Discovery Laboratories Inc.
• Durect Corporation
• Dyax Corporation
• Endo Pharmaceuticals
  Endo Pharmaceuticals
  Endo Pharmaceuticals Inc. is an American pharmaceutical company. It was created as a result of a management buyout from DuPont Merck in 1997. Three DuPont Merck executives Endo Pharmaceuticals Inc. is an American pharmaceutical company. It was created as a result of a management buyout from...
  
   Holdings Inc.
• Enzon Pharmaceuticals Inc.
• Exelixis
  Exelixis
  Exelixis is a genomics-based drug discovery company located in South San Francisco, Ca. It works on the development of anti-cancer therapies. Exelixis has several compounds in various stages of FDA approval including :...
  
   Inc.
• Facet Biotech Corporation
• Flamel Technologies S.A.
• Gen-Probe
  Gen-Probe
  Gen-Probe is a public biotechnology company based in San Diego, California employing approximately 1,300, and specializing in Clinical Diagnostics, Blood Screening, Transplant Products and Research Products...
  
   Incorporated
• Genomic Health Inc.
• Genzyme
  Genzyme
  Genzyme Corporation is a fully owned subsidiary of Sanofi-Aventis. Before its acquisition, Genzyme was an American biotechnology company based in Cambridge, Massachusetts. In 2010, Genzyme was the world’s third-largest biotechnology company, employing more than 11,000 people around the world...
  
   Corporation
• Geron Corporation 
• Gilead Sciences
  Gilead Sciences
  Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes therapeutics. For many years since the company was founded, the company concentrated primarily on antiviral drugs to treat patients infected with HIV, hepatitis B or influenza. In 2006, Gilead acquired two...
  
   Inc.
• GTx
  GTX
  GTX refer to:* Mazda Familia , turbocharged sub model* Plymouth GTX, car model* Sea-Doo GTX, watercraft model* GTx, Inc, a pharmaceutical company...
  
   Inc.
• Halozyme Therapeutics
  Halozyme Therapeutics
  Halozyme Therapeutics, based in San Diego, California, is a biopharmaceutical company developing and commercializing products targeting the extracellular matrix for the endocrinology, oncology, dermatology and drug delivery markets.* http://www.halozyme.com...
  
   Inc.
• Human Genome Sciences
  Human Genome Sciences
  Human Genome Sciences is a biopharmaceutical corporation founded in 1992. It uses the human DNA sequence to develop protein and antibody drugs. As of 2008, it has drugs under development to treat such diseases as hepatitis C, systemic lupus erythmatosis, anthrax disease, cancer, rheumatoid...
  
   Inc.
• Idenix Pharmaceuticals Inc.
• Illumina
  Illumina (company)
  Illumina, Inc. is a company incorporated in April 1998 that develops, manufactures and markets integrated systems for the analysis of genetic variation and biological function. Using its technologies, the company provides a line of products and services that serve the sequencing, genotyping and...
  
   Inc.
• ImmunoGen Inc.
• Immunomedics Inc.
• Impax Laboratories Inc.
• Incyte Corporation
• Inspire Pharmaceuticals Inc.
• InterMune Inc.
• Isis Pharmaceuticals Inc.
• Lexicon Pharmaceuticals
  Lexicon Pharmaceuticals
  Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company engaged in discovering and developing breakthrough treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated...
  
   Inc.
• Life Technologies
  Life Technologies
  Life Technologies is a global biotechnology company headquartered in Carlsbad, California. It possesses a portfolio of more than 9 million genetic research assays and custom solutions...
  
   Corporation
• Ligand Pharmaceuticals Incorporated
• Luminex Corporation
• MannKind Corporation
  MannKind Corporation
  MannKind Corporation , based in Valencia, California, is a biopharmaceutical company focusing on the discovery, development, and commercialization of therapeutic products for diseases such as diabetes and cancer. The company, while technically founded in February 1991, took its present form in 2003...
  
   
• Matrixx Initiatives Inc.
• Maxygen
  Maxygen
  Maxygen Inc. is a biopharmaceutical company focused on developing improved versions of protein drugs using DNA shuffling and other protein modification technologies...
  
   Inc.
• Medivation Inc.
• Micromet Inc.
• MiddleBrook Pharmaceuticals Inc.
• Momenta Pharmaceuticals Inc.
• Mylan Inc. 
• Myriad Genetics
  Myriad Genetics
  Myriad Genetics, Inc. is a molecular diagnostic company based in Salt Lake City, Utah. Myriad employs a number of proprietary technologies that permit doctors and patients to understand the genetic basis of human disease and the role that genes play in the onset, progression and treatment of disease...
  
   Inc.
• Nabi Biopharmaceuticals 
• Nektar Therapeutics 
• Neurocrine Biosciences
  Neurocrine Biosciences
  Neurocrine Biosciences is a biopharmaceutical company founded in 1992 and located in San Diego, California. The company tooks its name from the original focus on therapies for neurological and endocrine diseases and disorders....
  
   Inc.
• Novavax Inc.
• NPS Pharmaceuticals Inc.
• Obagi Medical Products Inc.
• ONYX Pharmaceuticals
  Onyx Pharmaceuticals
  Onyx Pharmaceuticals Inc. is a biopharmaceutical company headquartered in South San Francisco, California. The company develops and markets medicines for the treatment of cancer. Onyx was founded in 1992 by Frank McCormick Ph.D., FRS...
  
   Inc.
• Optimer Pharmaceuticals Inc.
• Orexigen Therapeutics Inc.
• OSI Pharmaceuticals
  OSI Pharmaceuticals
  OSI Pharmaceuticals, Inc. is an American pharmaceutical company based in Long Island, New York with facilities in Colorado, New Jersey and the United Kingdom. OSI specializes in the discovery and development of molecular targeted therapies, and was listed in the NASDAQ Biotechnology Index...
  
   Inc.
• Osiris Therapeutics Inc.
• Pain Therapeutics 
• PDL BioPharma Inc.
• Perrigo
  Perrigo
  Perrigo Company , is the largest manufacturer of private label over-the-counter pharmaceuticals in the United States. The company’s shares are traded on the NASDAQ and the Tel Aviv Stock Exchange; as a result of the merger with Agis Industries the company is a constituent of the TA-25...
  
   Company
• Pharmasset
  Pharmasset
  Pharmasset Inc. is a pharmaceutical company based in Princeton, New Jersey in the United States. The company develops antiviral drugs for HIV , hepatitis B , and hepatitis C. In November 2011, Pharmasset was acquired by Gilead for $11 billion.-History:Pharmasset was founded in 1998 by Dr. Raymond...
  
   Inc.
• Pozen Inc.
• Progenics Pharmaceuticals Inc.
• Qiagen
  Qiagen
  Qiagen is a provider of sample and assay technologies for molecular diagnostics, applied testing, academic and pharmaceutical research. Consolidated under the Dutch holding Qiagen N.V., the company operates more than 30 subsidiaries in over 18 countries. Qiagen’s shares are listed at the...
  
   N.V.
• QLT Inc.
• Questcor Pharmaceuticals Inc.
• Regeneron Pharmaceuticals Inc.
  Regeneron
  Regeneron is a biotechnology company headquartered in Tarrytown, in New York, USA. The company was founded in 1988. Originally focused on neurotrophic factors and their regenerative capabilities , it branched out into the study of both cytokine and tyrosine kinase receptors - leading to the three...
  
   
• Rigel Pharmaceuticals Inc.
• Salix Pharmaceuticals Ltd.
• Sangamo BioSciences Inc.
• Santarus Inc.
• Savient Pharmaceuticals Inc
• Seattle Genetics Inc.
• Sequenom
  Sequenom
  Sequenom is a manufacturer of DNA massarrays, based in San Diego, California, United States. The MassARRAY platform is used for SNP genotyping, methylation detection and quantitative gene expression analysis. Sequenom also manufactures clinical tests, such as SEQureDx, a noninvasive prenatal test...
  
   Inc.
• Shire
  Shire
  A shire is a traditional term for a division of land, found in the United Kingdom and in Australia. In parts of Australia, a shire is an administrative unit, but it is not synonymous with "county" there, which is a land registration unit. Individually, or as a suffix in Scotland and in the far...
  
   plc
• StemCells Inc.
• SuperGen Inc.
• Synta Pharmaceuticals Corp.
• Targacept
  Targacept
  Targacept is a pharmaceutical company based in Winston-Salem, North Carolina that specializes in developing drugs which target the nicotinic acetylcholine receptors....
  
   Inc.
• Techne Corporation 
• Teva Pharmaceutical Industries
  Teva Pharmaceutical Industries
  Teva Pharmaceutical Industries Ltd. , is an international pharmaceutical company headquartered in Petah Tikva, Israel. It specializes in generic and proprietary pharmaceuticals and active pharmaceutical ingredients...
  
   
• The Medicines Company
• Theravance Inc.
• United Therapeutics Corporation
• Vanda Pharmaceuticals Inc.
• Vertex Pharmaceuticals
  Vertex Pharmaceuticals
  Vertex Pharmaceuticals is a biotechnology company with activities spanning the length of the pharmaceutical product pipeline, from target identification through to clinical trials and marketing. Most of its activity has been in collaboration with much larger pharmaceutical firms, though some of its...
  
   Incorporated
• Vical Incorporated
• ViroPharma
  ViroPharma
  ViroPharma Incorporated, a pharmaceutical company, develops and sells drugs that address serious diseases treated by physician specialists and in hospital settings...
  
   Incorporated
• VIVUS
  Vivus
  Vivus is a small pharmacutical company working in obesity, sleep, and sexual health. Vivus is developing an erectile dysfunction drug, Avanafil, that is in Phase 3 clinical trials.-External links:*...
  
   Inc.
• Warner Chilcott
  Warner Chilcott
  Warner Chilcott is a pharmaceutical company based in Rockaway, New Jersey, USA. It has production and research facilities in Fajardo, Puerto Rico, Larne, Northern Ireland, Dundalk, Ireland and Weiterstadt, Germany. It is primarily focused on two core therapeutic areas: women’s healthcare and...
  
   plc
• XenoPort Inc.
• XOMA Ltd.
• ZymoGenetics
  ZymoGenetics
  ZymoGenetics is a biotechnology/pharmaceutical company based in Seattle, Washington, involved in the development of therapeutic proteins.The company was founded in 1981 by Professors Earl W. Davie and Benjamin D. Hall of the University of Washington and 1993 Nobel Laureate in Chemistry Michael...
  
  Inc.

External links

• Nasdaq Biotechnology Index
• Yahoo! Finance page for NASDAQ Biotechnology