Nucleoside transporter
Encyclopedia
Nucleoside transporters are a group of membrane transport proteins which transport nucleoside
substrates
like adenosine across the membrane
s of cell
s and/or vesicles
. There are two known types of nucleoside transporters, concentrative nucleoside transporters (CNTs; SLC28) and equilibrative nucleoside transporter
s (ENTs; SLC29), as well as possibly a yet-unidentified vesicular transporter.
Nucleoside
Nucleosides are glycosylamines consisting of a nucleobase bound to a ribose or deoxyribose sugar via a beta-glycosidic linkage...
substrates
Substrate (biochemistry)
In biochemistry, a substrate is a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the substrate. In the case of a single substrate, the substrate binds with the enzyme active site, and an enzyme-substrate complex is formed. The substrate is transformed into one or...
like adenosine across the membrane
Biological membrane
A biological membrane or biomembrane is an enclosing or separatingmembrane that acts as a selective barrier, within or around a cell. It consists of a lipid bilayer with embedded proteins that may constitute close to 50% of membrane content...
s of cell
Cell (biology)
The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos....
s and/or vesicles
Vesicle (biology)
A vesicle is a bubble of liquid within another liquid, a supramolecular assembly made up of many different molecules. More technically, a vesicle is a small membrane-enclosed sack that can store or transport substances. Vesicles can form naturally because of the properties of lipid membranes , or...
. There are two known types of nucleoside transporters, concentrative nucleoside transporters (CNTs; SLC28) and equilibrative nucleoside transporter
Equilibrative nucleoside transporter
The equilibrative nucleoside transporter family, also known as SLC29, is a group of plasmalemmal transport proteins which transport nucleoside substrates like adenosine into cells. There are four known ENTs, designated ENT1, ENT2, ENT3, and ENT4...
s (ENTs; SLC29), as well as possibly a yet-unidentified vesicular transporter.