RBBP8
Encyclopedia
Retinoblastoma-binding protein 8 is a protein
that in humans is encoded by the RBBP8 gene
.
with LMO4
, Retinoblastoma-like protein 2
, Retinoblastoma-like protein 1
, Ataxia telangiectasia mutated
, Retinoblastoma protein
, CTBP1
, SIAH1
and BRCA1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the RBBP8 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
RBBP8 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with LMO4
LMO4
LIM domain transcription factor LMO4 is a protein that in humans is encoded by the LMO4 gene.-Interactions:LMO4 has been shown to interact with LDB1, RBBP8 and BRCA1.-Further reading:...
, Retinoblastoma-like protein 2
Retinoblastoma-like protein 2
Retinoblastoma-like protein 2 is a protein that in humans is encoded by the RBL2 gene.-Interactions:Retinoblastoma-like protein 2 has been shown to interact with HDAC1, C-Raf, RBBP8, Cyclin E1, Prohibitin, Cyclin-dependent kinase 2, BRF1 and BRCA1....
, Retinoblastoma-like protein 1
Retinoblastoma-like protein 1
Retinoblastoma-like 1 , also known as RBL1, is a protein that in humans is encoded by the RBL1 gene.- Function :The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 gene...
, Ataxia telangiectasia mutated
Ataxia telangiectasia mutated
Ataxia telangiectasia mutated is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis...
, Retinoblastoma protein
Retinoblastoma protein
The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in the majority types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide...
, CTBP1
CTBP1
C-terminal-binding protein 1 also known as CtBP1 is a protein that in humans is encoded by the CTBP1 gene.- Function :The CtBP1 protein binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation...
, SIAH1
SIAH1
E3 ubiquitin-protein ligase SIAH1 is an enzyme that in humans is encoded by the SIAH1 gene.-Interactions:SIAH1 has been shown to interact with PEG10, CACYBP, POU2AF1, RBBP8, BAG1, TRIB3, NUMB, KIF22, KHDRBS3, PEG3 and APC.-References:...
and BRCA1
BRCA1
BRCA1 is a human caretaker gene that produces a protein called breast cancer type 1 susceptibility protein, responsible for repairing DNA. The first evidence for the existence of the gene was provided by the King laboratory at UC Berkeley in 1990...
.