Imidazopyridine
Encyclopedia
The imidazopyridines are a class of drugs
defined by their chemical structure. They are generally GABAA receptor agonists, however recently proton pump inhibitors in this class have been developed as well. Despite usually being similar to them in effect, they are not chemically related to benzodiazepines. As such, GABAA agonizing imidazopyridines, pyrazolopyrimidine
s, and cyclopyrrones are sometimes grouped together and referred to as "nonbenzodiazepine
s." Imidazopyridines include:
GABAA Receptor Agonists
Proton Pump Inhibitors
Medication
A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease.- Classification :...
defined by their chemical structure. They are generally GABAA receptor agonists, however recently proton pump inhibitors in this class have been developed as well. Despite usually being similar to them in effect, they are not chemically related to benzodiazepines. As such, GABAA agonizing imidazopyridines, pyrazolopyrimidine
Pyrazolopyrimidine
Pyrazolopyrimidine is a heterocyclic chemical compound with the molecular formula C6H5N3. It forms the central core of a variety of more complex chemical compounds including some pharmaceuticals and pesticides.-Pharmaceuticals:...
s, and cyclopyrrones are sometimes grouped together and referred to as "nonbenzodiazepine
Nonbenzodiazepine
The nonbenzodiazepines, also called benzodiazepine-like drugs, are a class of psychoactive drugs pharmacologically resembling the benzodiazepines, with similar benefits, side effects and risks, despite having dissimilar or entirely different chemical structures.-Classes:There are currently three...
s." Imidazopyridines include:
GABAA Receptor Agonists
- ZolpidemZolpidemZolpidem is a prescription medication used for the short-term treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic of the imidazopyridine class that potentiates gamma-aminobutyric acid , an inhibitory neurotransmitter, by binding to GABAA...
(Ambien) - AlpidemAlpidemAlpidem is an anxiolytic drug from the imidazopyridine family, related to the more well known sleeping medication zolpidem. Unlike zolpidem however, alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety.Alipidem was developed by ...
- SaripidemSaripidemSaripidem is a sedative and anxiolytic drug in the imidazopyridine family, which is related to the better known drugs zolpidem and alpidem.Saripidem has a similar pharmacological profile to the benzodiazepine family of drugs including sedative and anxiolytic properties, but its chemical structure...
- NecopidemNecopidemNecopidem is a drug in the imidazopyridine family, which is related to the better known drugs zolpidem and alpidem. It has sedative and anxiolytic effects....
- DS-1 (drug)DS-1 (drug)DS-1 is a drug from the imidazopyridine family which is the first drug developed that acts as a GABAA receptor agonist selective for the α4β3δ subtype, which is not targeted by other GABA agonists such as the benzodiazepines or other nonbenzodiazepine drugs. Novel selective drugs such as DS-1...
Proton Pump Inhibitors
- TenatoprazoleTenatoprazoleTenatoprazole , discovered in Japan, is a proton pump inhibitor indicated for the treatment of reflux oesophagitis and peptic ulcer. Discovered by Mitsubishi Pharma, it is an imidazopyridine derivative and has an imidazopyridine ring in place of the benzimidazole moiety found in other proton pump...