Schering-Plough
Encyclopedia
Schering-Plough Corporation was a United States
-based pharmaceutical company. It was founded in 1851 by Ernst Christian Friedrich Schering
as Schering AG
in Germany
. In 1971, the Schering Corporation merged with Plough (founded by Memphis area entrepreneur Abe Plough in 1908 ) to form Schering-Plough. On November 4, 2009 Merck & Co.
was merged with Schering-Plough with the new company taking the name of Merck & Co.
Schering-Plough manufactured several pharmaceutical drugs
, the most well-known of which were the allergy
drugs Claritin and Clarinex, an anti-cholesterol
drug Vytorin, and a brain tumor
drug Temodar. These are now available from Merck & Co.
Schering Plough also owned and operated the major foot
care brand name Dr. Scholl's
and the skin
care line Coppertone. These also became a part of the new company.
, Schering-Plough had 1.4% market share in the U.S., placing it seventeenth in the top twenty pharmaceutical corporations by sales compiled by IMS Health
.
Schering-Plough was a full member of the European Federation of Pharmaceutical Industries and Associations
(EFPIA), a membership which is also maintained by the new Merck.
as Schering AG in Germany
.
Following the entry of the United States
into World War II
in 1941, U.S. President Franklin Delano Roosevelt ordered Schering AG
's U.S. assets be seized. These became the Schering Corporation. The company was placed under a government administratorship until 1952, when it was released and its assets sold to the private sector.
Plough, Incorporated was founded by the Memphis, Tennessee
area entrepreneur Abe Plough in 1908 http://www.societyofentrepreneurs.com/hall_honor/plough.asp. He borrowed $125 from his father to start the business at age sixteen. As a one man business, he mixed "Plough's Antiseptic Healing Oil," a "sure cure for any ill of man or beast," and sold it off a horse-drawn buggy. He grew the company through sound management and innovative strategies, with marketing genius.
Plough's acquisitions included St Joseph's Aspirin for children, Maybelline
cosmetics, and Coppertone
skin care products. Plough also had a broadcasting division, operating radio stations in Atlanta, Georgia
; Baltimore, Maryland; Boston, Massachusetts; Chicago, Illinois; and Memphis, Tennessee
.
In 1971, the Schering Corporation merged with Plough, Inc. At the time of the merger, Abe Plough became Chairman of the combined company.
In 2000, Schering Plough bought a new campus in Summit, New Jersey
from Novartis
. The company planned to make this location its second-largest corporate complex in the world after completion of its current $20 million renovation.
Schering-Plough was named one of the 100 Best Companies for Working Mothers in 2004 and 2005 by Working Mothers magazine.
On March 9, 2009 it was announced that Schering-Plough and Merck were to merge. On November 4, 2009 Schering-Plough merged with Merck & Co.
and through a reverse merger
Merck became a subsidiary of Schering-Plough, which renamed itself Merck.
's isolation has formed a natural quarantine
, leaving the country free of rabies
, foot and mouth, scrapie
, bovine spongiform encephalopathy
, and many other livestock diseases. It formerly had echinococcosis
, but this has been eradicated. The site was known locally as "Coopers Animal Health," a trademark which was still in use by Schering-Plough in Australia, but not elsewhere.
On 12 March 2007, Schering-Plough Corp. purchased Organon International
, the drug unit of Netherlands-based Akzo Nobel, for $14.4 billion, giving the US pharmaceutical company an array of women's health products and numerous late-stage pipelines of experimental medicines.
Organon
itself was founded in 1923 by Dr. Saal van Zwanenberg, the president of Zwanenberg’s Slachterijen en Fabrieken. The company is housed at Zwanenberg’s premises in Oss, the Netherlands..
By August 21, 2008, Famvir (famciclovir
) was marketed by Schering-Plough; formerly it was marketed by Novartis
.
As a result of the acquisition of Organon BioSciences, Schering-Plough bolstered its animal health business with the Akzo Nobel
subsidiary Intervet, obtained control of the active pharmaceutical ingredient manufacturer, Diosynth
and gained access to human vaccine production through the subsidiary Nobilon. The three companies comprising Organon BioSciences were--Organon, Diosynth, and Intervet.
After the merger of Schering-Plough with Merck the animal health division was still known as Intervet/Schering-Plough Animal Health. A merger of Merial and Intervet/Schering-Plough was planned in 2010, but was abandoned in March 2011. On June 29, 2011, the company announced that the animal health division would now be known as Merck Animal Health in the United States and Canada; it is now called MSD Animal Health elsewhere in the world.
.
safety assessment was the InnoMed PredTox.
Schering-Plough entered into a Consent Decree with the FDA on March 6, 2002 due to manufacturing issues with its albuterol inhaler. It was ordered to pay $500 Million US dollars to the US Treasury.
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
-based pharmaceutical company. It was founded in 1851 by Ernst Christian Friedrich Schering
Ernst Christian Friedrich Schering
Ernst Christian Friedrich Schering was a German apothecary and industrialist who created the Schering Corporation. The company split into Schering AG and Schering-Plough after US assets were seized during World War II....
as Schering AG
Schering
Schering AG was a research-centered German pharmaceutical company. It was founded in 1851 by Ernst Christian Friedrich Schering and merged with Bayer's pharma sector in December 2006. The company's headquarters was in Berlin-Wedding, Germany...
in Germany
Germany
Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...
. In 1971, the Schering Corporation merged with Plough (founded by Memphis area entrepreneur Abe Plough in 1908 ) to form Schering-Plough. On November 4, 2009 Merck & Co.
Merck & Co.
Merck & Co., Inc. , also known as Merck Sharp & Dohme or MSD outside the United States and Canada, is one of the largest pharmaceutical companies in the world. The Merck headquarters is located in Whitehouse Station, New Jersey, an unincorporated area in Readington Township...
was merged with Schering-Plough with the new company taking the name of Merck & Co.
Schering-Plough manufactured several pharmaceutical drugs
Medication
A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease.- Classification :...
, the most well-known of which were the allergy
Allergy
An Allergy is a hypersensitivity disorder of the immune system. Allergic reactions occur when a person's immune system reacts to normally harmless substances in the environment. A substance that causes a reaction is called an allergen. These reactions are acquired, predictable, and rapid...
drugs Claritin and Clarinex, an anti-cholesterol
Cholesterol
Cholesterol is a complex isoprenoid. Specifically, it is a waxy steroid of fat that is produced in the liver or intestines. It is used to produce hormones and cell membranes and is transported in the blood plasma of all mammals. It is an essential structural component of mammalian cell membranes...
drug Vytorin, and a brain tumor
Brain tumor
A brain tumor is an intracranial solid neoplasm, a tumor within the brain or the central spinal canal.Brain tumors include all tumors inside the cranium or in the central spinal canal...
drug Temodar. These are now available from Merck & Co.
Schering Plough also owned and operated the major foot
Foot
The foot is an anatomical structure found in many vertebrates. It is the terminal portion of a limb which bears weight and allows locomotion. In many animals with feet, the foot is a separate organ at the terminal part of the leg made up of one or more segments or bones, generally including claws...
care brand name Dr. Scholl's
Dr. Scholl's
William Mathias Scholl was a podiatrist, pioneer of foot care and the founder of Dr. Scholl's, a brand of foot care products. Scholl went on to found the Illinois College of Chiropody and Orthopaedics. William M...
and the skin
Skin
-Dermis:The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis is tightly connected to the epidermis by a basement membrane. It also harbors many Mechanoreceptors that provide the sense of touch and heat...
care line Coppertone. These also became a part of the new company.
, Schering-Plough had 1.4% market share in the U.S., placing it seventeenth in the top twenty pharmaceutical corporations by sales compiled by IMS Health
IMS Health
IMS Health is an international company that supplies the pharmaceutical industry with sales data and consulting services. IMS Health was founded in 1954 by Bill Froch and David Dubow. Today IMS has operations in more than 100 countries, a global workforce of 7,600+ employees, and revenues of $2...
.
Schering-Plough was a full member of the European Federation of Pharmaceutical Industries and Associations
European Federation of Pharmaceutical Industries and Associations
European Federation of Pharmaceutical Industries and Associations is a Brussels-based trade union founded in 1978 representing the research-based pharmaceutical industry operating in Europe....
(EFPIA), a membership which is also maintained by the new Merck.
Pharmaceuticals and consumer products
Schering was founded in 1851 by Ernst Christian Friedrich ScheringErnst Christian Friedrich Schering
Ernst Christian Friedrich Schering was a German apothecary and industrialist who created the Schering Corporation. The company split into Schering AG and Schering-Plough after US assets were seized during World War II....
as Schering AG in Germany
Germany
Germany , officially the Federal Republic of Germany , is a federal parliamentary republic in Europe. The country consists of 16 states while the capital and largest city is Berlin. Germany covers an area of 357,021 km2 and has a largely temperate seasonal climate...
.
Following the entry of the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
into World War II
World War II
World War II, or the Second World War , was a global conflict lasting from 1939 to 1945, involving most of the world's nations—including all of the great powers—eventually forming two opposing military alliances: the Allies and the Axis...
in 1941, U.S. President Franklin Delano Roosevelt ordered Schering AG
Schering
Schering AG was a research-centered German pharmaceutical company. It was founded in 1851 by Ernst Christian Friedrich Schering and merged with Bayer's pharma sector in December 2006. The company's headquarters was in Berlin-Wedding, Germany...
's U.S. assets be seized. These became the Schering Corporation. The company was placed under a government administratorship until 1952, when it was released and its assets sold to the private sector.
Plough, Incorporated was founded by the Memphis, Tennessee
Memphis, Tennessee
Memphis is a city in the southwestern corner of the U.S. state of Tennessee, and the county seat of Shelby County. The city is located on the 4th Chickasaw Bluff, south of the confluence of the Wolf and Mississippi rivers....
area entrepreneur Abe Plough in 1908 http://www.societyofentrepreneurs.com/hall_honor/plough.asp. He borrowed $125 from his father to start the business at age sixteen. As a one man business, he mixed "Plough's Antiseptic Healing Oil," a "sure cure for any ill of man or beast," and sold it off a horse-drawn buggy. He grew the company through sound management and innovative strategies, with marketing genius.
Plough's acquisitions included St Joseph's Aspirin for children, Maybelline
Maybelline
Maybelline is an American makeup brand sold worldwide and owned by L'Oréal. Their motto is Maybe she's born with it. Maybe it's Maybelline.-History:...
cosmetics, and Coppertone
Coppertone girl
Coppertone is the brand name for an American sunscreen, owned by Merck, formerly Schering-Plough. Coppertone is the sister brand to Bain de Soleil, which is targeted to adult females....
skin care products. Plough also had a broadcasting division, operating radio stations in Atlanta, Georgia
Atlanta, Georgia
Atlanta is the capital and most populous city in the U.S. state of Georgia. According to the 2010 census, Atlanta's population is 420,003. Atlanta is the cultural and economic center of the Atlanta metropolitan area, which is home to 5,268,860 people and is the ninth largest metropolitan area in...
; Baltimore, Maryland; Boston, Massachusetts; Chicago, Illinois; and Memphis, Tennessee
Memphis, Tennessee
Memphis is a city in the southwestern corner of the U.S. state of Tennessee, and the county seat of Shelby County. The city is located on the 4th Chickasaw Bluff, south of the confluence of the Wolf and Mississippi rivers....
.
In 1971, the Schering Corporation merged with Plough, Inc. At the time of the merger, Abe Plough became Chairman of the combined company.
In 2000, Schering Plough bought a new campus in Summit, New Jersey
Summit, New Jersey
Summit is a city in Union County, New Jersey, United States. At the 2010 United States Census, the city's population was 21,457. Summit had the 16th-highest per capita income in the state as of the 2000 Census....
from Novartis
Novartis
Novartis International AG is a multinational pharmaceutical company based in Basel, Switzerland, ranking number three in sales among the world-wide industry...
. The company planned to make this location its second-largest corporate complex in the world after completion of its current $20 million renovation.
Schering-Plough was named one of the 100 Best Companies for Working Mothers in 2004 and 2005 by Working Mothers magazine.
On March 9, 2009 it was announced that Schering-Plough and Merck were to merge. On November 4, 2009 Schering-Plough merged with Merck & Co.
Merck & Co.
Merck & Co., Inc. , also known as Merck Sharp & Dohme or MSD outside the United States and Canada, is one of the largest pharmaceutical companies in the world. The Merck headquarters is located in Whitehouse Station, New Jersey, an unincorporated area in Readington Township...
and through a reverse merger
Reverse takeover
A reverse takeover or reverse merger is the acquisition of a public company by a private company so that the private company can bypass the lengthy and complex process of going public...
Merck became a subsidiary of Schering-Plough, which renamed itself Merck.
Animal health
One of Schering-Plough's plants, in Upper Hutt, New Zealand was the largest single site for the production of veterinary vaccines in the world. This was primarily because New ZealandNew Zealand
New Zealand is an island country in the south-western Pacific Ocean comprising two main landmasses and numerous smaller islands. The country is situated some east of Australia across the Tasman Sea, and roughly south of the Pacific island nations of New Caledonia, Fiji, and Tonga...
's isolation has formed a natural quarantine
Quarantine
Quarantine is compulsory isolation, typically to contain the spread of something considered dangerous, often but not always disease. The word comes from the Italian quarantena, meaning forty-day period....
, leaving the country free of rabies
Rabies
Rabies is a viral disease that causes acute encephalitis in warm-blooded animals. It is zoonotic , most commonly by a bite from an infected animal. For a human, rabies is almost invariably fatal if post-exposure prophylaxis is not administered prior to the onset of severe symptoms...
, foot and mouth, scrapie
Scrapie
Scrapie is a fatal, degenerative disease that affects the nervous systems of sheep and goats. It is one of several transmissible spongiform encephalopathies , which are related to bovine spongiform encephalopathy and chronic wasting disease of deer. Like other spongiform encephalopathies, scrapie...
, bovine spongiform encephalopathy
Bovine spongiform encephalopathy
Bovine spongiform encephalopathy , commonly known as mad-cow disease, is a fatal neurodegenerative disease in cattle that causes a spongy degeneration in the brain and spinal cord. BSE has a long incubation period, about 30 months to 8 years, usually affecting adult cattle at a peak age onset of...
, and many other livestock diseases. It formerly had echinococcosis
Echinococcosis
Echinococcosis, which is often referred to as hydatid disease or echinococcal disease, is a parasitic disease that affects both humans and other mammals, such as sheep, dogs, rodents and horses. There are three different forms of echinococcosis found in humans, each of which is caused by the larval...
, but this has been eradicated. The site was known locally as "Coopers Animal Health," a trademark which was still in use by Schering-Plough in Australia, but not elsewhere.
On 12 March 2007, Schering-Plough Corp. purchased Organon International
Organon International
Organon is a human pharmaceutical company headquartered in Oss, Netherlands. In November 2007 the company became a part of Schering-Plough Corporation, acquired Organon, active pharmaceutical ingredient producer Diosynth , and its veterinary pharmaceutical sister company Intervet from Akzo Nobel. ...
, the drug unit of Netherlands-based Akzo Nobel, for $14.4 billion, giving the US pharmaceutical company an array of women's health products and numerous late-stage pipelines of experimental medicines.
Organon
Organon International
Organon is a human pharmaceutical company headquartered in Oss, Netherlands. In November 2007 the company became a part of Schering-Plough Corporation, acquired Organon, active pharmaceutical ingredient producer Diosynth , and its veterinary pharmaceutical sister company Intervet from Akzo Nobel. ...
itself was founded in 1923 by Dr. Saal van Zwanenberg, the president of Zwanenberg’s Slachterijen en Fabrieken. The company is housed at Zwanenberg’s premises in Oss, the Netherlands..
By August 21, 2008, Famvir (famciclovir
Famciclovir
Famciclovir is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster . It is a prodrug form of penciclovir with improved oral bioavailability...
) was marketed by Schering-Plough; formerly it was marketed by Novartis
Novartis
Novartis International AG is a multinational pharmaceutical company based in Basel, Switzerland, ranking number three in sales among the world-wide industry...
.
As a result of the acquisition of Organon BioSciences, Schering-Plough bolstered its animal health business with the Akzo Nobel
Akzo Nobel
Akzo Nobel N.V., trading as AkzoNobel, is a Dutch multinational, active in the fields of decorative paints, performance coatings and specialty chemicals. Headquartered in Amsterdam, the company has activities in more than 80 countries, and employs approximately 55,000 people. Sales in 2010 were EUR...
subsidiary Intervet, obtained control of the active pharmaceutical ingredient manufacturer, Diosynth
Diosynth
Diosynth is a company that develops manufacturing processes for active ingredients for pharmaceutical companies all over the world.The company started in Oss, Netherlands in 1923 with the extraction of insulin from bovine pancreas, and porcine insulin extraction in 1930, both of which are still...
and gained access to human vaccine production through the subsidiary Nobilon. The three companies comprising Organon BioSciences were--Organon, Diosynth, and Intervet.
After the merger of Schering-Plough with Merck the animal health division was still known as Intervet/Schering-Plough Animal Health. A merger of Merial and Intervet/Schering-Plough was planned in 2010, but was abandoned in March 2011. On June 29, 2011, the company announced that the animal health division would now be known as Merck Animal Health in the United States and Canada; it is now called MSD Animal Health elsewhere in the world.
Chief executives
| Name | Tenure |
|---|---|
| Willibald H. Cozen | 1971 – 1979 |
| Richard J. Bennett | 1979 – January 31, 1982 |
| Robert P. Luciano | February 1, 1982 – December 31, 1995 |
| Richard J. Kogan | January 1, 1996 – April 2003 |
| Fred Hassan Fred Hassan Fred Hassan , a native of Pakistan, who was the Chairman of the Board and Chief Executive Officer of pharmaceutical company Schering-Plough from 2003 until November 3, 2009 when the company completed its merger with Merck & Co..... |
April 2003 – November 3, 2009 |
Prescription products
- Bridion (sugammadexSugammadexSugammadex is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent and was discovered at the Newhouse research site in Scotland. . These scientists who discovered Sugammadex worked for the pharmaceutical...
) - Cerazette
- DesloratadineDesloratadineDesloratadine is a drug used to treat allergies. It is marketed under several trade names such as NeoClarityn, Claramax, Clarinex, Larinex, Aerius, Dazit, Azomyr and Delot...
- antihistamineAntihistamineAn H1 antagonist is a histamine antagonist of the H1 receptor that serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions...
branded Neoclarityn - Esmeron/Zemuron (rocuroniumRocuroniumRocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.Introduced in 1994, rocuronium has...
) - Famvir (FamciclovirFamciclovirFamciclovir is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster . It is a prodrug form of penciclovir with improved oral bioavailability...
) - for herpes zosterHerpes zosterHerpes zoster , commonly known as shingles and also known as zona, is a viral disease characterized by a painful skin rash with blisters in a limited area on one side of the body, often in a stripe...
and shingles zoster treatment formerly NovartisNovartisNovartis International AG is a multinational pharmaceutical company based in Basel, Switzerland, ranking number three in sales among the world-wide industry... - Intron A & PEG-Intron Interferon alfa-2bInterferon alfa-2bInterferon alfa-2b is an antiviral drug originally discovered in the laboratory of Charles Weissmann at the University of Zurich, developed at Biogen, and ultimately marketed by Schering-Plough under the tradename Intron-A...
- Hep C - Levitra (vardenafilVardenafilVardenafil is a PDE5 inhibitor used for treating erectile dysfunction that is sold under the trade names Levitra and Staxyn.-History:...
) - Erectile-dysfunction drug; co-marketed with BayerBayerBayer AG is a chemical and pharmaceutical company founded in Barmen , Germany in 1863. It is headquartered in Leverkusen, North Rhine-Westphalia, Germany and well known for its original brand of aspirin.-History:...
,and GlaxoSmithKlineGlaxoSmithKlineGlaxoSmithKline plc is a global pharmaceutical, biologics, vaccines and consumer healthcare company headquartered in London, United Kingdom... - Livial (tiboloneTiboloneTibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist at all five of the Type I steroid hormone receptors. It is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women...
) - Marvelon/Desogen
- Nasonex and Asmanex (Mometasone furoateMometasone furoateMometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways.-Uses, administration, and pharmacodynamics:...
) - Noxafil (posaconazolePosaconazolePosaconazole is a triazole antifungal drug.Posaconazole is marketed in the United States, the European Union, and in other countries by Schering-Plough under the trade name Noxafil...
) - NuvaRing
- Puregon/Follistim
- QuazepamQuazepamQuazepam is a benzodiazepine derivative drug developed by the Schering Corporation in the 1970s. Quazepam is indicated for the treatment of insomnia including sleep induction and sleep maintenance...
(Doral) - Remeron/Remeron SolTab (mirtazapineMirtazapineMirtazapine is a tetracyclic antidepressant used primarily in the treatment of depression. It is also sometimes used as a hypnotic, antiemetic, and appetite stimulant, and for the treatment of anxiety, among other indications...
) - Remicade (infliximabInfliximabInfliximab is a monoclonal antibody against tumour necrosis factor alpha . It is used to treat autoimmune diseases. Remicade is marketed by Janssen Biotech, Inc...
) - Temodar (temozolomideTemozolomideTemozolomide Temozolomide Temozolomide (brand names Temodar and Temodal is an oral alkylating agent which can be used for the treatment of Grade IV astrocytoma — an aggressive brain tumor, also known as glioblastoma multiforme as well as melanoma, a form of skin cancer...
) - Vytorin (ezetimibe/simvastatinEzetimibe/simvastatinEzetimibe/simvastatin is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe and the statin drug simvastatin...
) - Cholesterol-lowering combination drug - Zetia (ezetimibeEzetimibeEzetimibe is a drug that lowers cholesterol. It acts by decreasing cholesterol absorption in the intestine. It may be used alone , when other cholesterol-lowering medications are not tolerated, or together with statins when statins alone do not control cholesterol.Even though ezetimibe decreases...
) - Cholesterol-lowering drug
Over-the-counter products
- Afrin - A nasal sprayNasal sprayNasal sprays come in a variety of forms. Medicated such as Astelin, Afrin and Nasonex and natural such as Sinusoothe and Sterimar. Although delivery methods vary, most nasal sprays function by instilling a fine mist into the nostril by action of a hand-operated pump mechanism.-Antihistamine nasal...
decongestant - Claritin (loratadineLoratadineLoratadine is a second-generation H1 histamine antagonist drug used to treat allergies. Structurally, it is closely related to tricyclic antidepressants such as imipramine, and distantly related to the atypical antipsychotic quetiapine. It is marketed by Schering-Plough under several trade names...
) - An antihistamineAntihistamineAn H1 antagonist is a histamine antagonist of the H1 receptor that serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions...
which has less risk of causing drowsiness - CoricidinCoricidinCoricidin, Coricidin 'D , or CoricidinHBP , is the name of a drug marketed by Schering-Plough that contains dextromethorphan and chlorpheniramine maleate...
- A palliativePalliative carePalliative care is a specialized area of healthcare that focuses on relieving and preventing the suffering of patients...
remedy for the common coldCommon coldThe common cold is a viral infectious disease of the upper respiratory system, caused primarily by rhinoviruses and coronaviruses. Common symptoms include a cough, sore throat, runny nose, and fever...
, targeted towards individuals with high blood pressureHypertensionHypertension or high blood pressure is a cardiac chronic medical condition in which the systemic arterial blood pressure is elevated. What that means is that the heart is having to work harder than it should to pump the blood around the body. Blood pressure involves two measurements, systolic and... - Coppertone - sunscreens
- Bain de SoleilBain de SoleilBain de Soleil is a brand of sunscreen produced by Merck, formerly Schering-Plough Consumer Health Care. It is affiliated with the Coppertone brand...
- suncreen - Drixoral
- Dr. Scholl'sDr. Scholl'sWilliam Mathias Scholl was a podiatrist, pioneer of foot care and the founder of Dr. Scholl's, a brand of foot care products. Scholl went on to found the Illinois College of Chiropody and Orthopaedics. William M...
line of products - ZinkaZinkaZinka is a brand of sunscreen produced by the Schering-Plough Corporation, the makers of Coppertone. Originating in Southern California and popular in the late 1980s, the zinc oxide product comes in an array of nine colors "so that wacky youths can come to the beach as Indians on the warpath."...
- Colored sunscreen
Veterinary products
- Home Again Pet Recovery SystemHome Again Pet Recovery SystemHome Again Pet Recovery System, manufactured by Schering-Plough, is one of the two main electronic pet tagging systems used in the US . Much of the rest of the world uses similar chips based on ISO 11784 and ISO 11785, instead....
- HomeAgain is an advanced pet identification and retrieval system. - ZubrinZubrinZubrin: * Tepoxalin* Robert Zubrin , an American aerospace engineer and author* Vladimir Viktorovich Zubrin - See also :Related toponyms:* Zubra * Zúbra * Zubří * Zubrzyk...
- A non-steroidal anti-inflammatory drug (NSAID) for the treatment of osteoarthritisOsteoarthritisOsteoarthritis also known as degenerative arthritis or degenerative joint disease, is a group of mechanical abnormalities involving degradation of joints, including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion...
in dogs. - Mometamax - Is indicated for the treatment of canine acute externa and chronic otitis externa associated with yeastYeastYeasts are eukaryotic micro-organisms classified in the kingdom Fungi, with 1,500 species currently described estimated to be only 1% of all fungal species. Most reproduce asexually by mitosis, and many do so by an asymmetric division process called budding...
(Malassezia pachydermatis, formerly Pityrosporum canis) and/or bacteriaBacteriaBacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...
susceptible to gentamicinGentamicinGentamicin is an aminoglycoside antibiotic, used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms. However, gentamicin is not used for Neisseria gonorrhoeae, Neisseria meningitidis or Legionella pneumophila...
. It contains the strongest steroid (Mometasone furoateMometasone furoateMometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways.-Uses, administration, and pharmacodynamics:...
) in Veterinary Medicine. - Eclipse Vaccines - Attenuated modified live feline vaccines available in a multitude of antigenAntigenAn antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then kill or neutralize the antigen that is recognized as a foreign and potentially harmful invader. These invaders can be molecules such as...
combinations. - Galaxy Vaccines - Canine vaccines available in a multitude of antigenAntigenAn antigen is a foreign molecule that, when introduced into the body, triggers the production of an antibody by the immune system. The immune system will then kill or neutralize the antigen that is recognized as a foreign and potentially harmful invader. These invaders can be molecules such as...
combinations. - OptimmuneOptimmuneOptimmune is an ophthalmic ointment with cyclosporine as the active ingredient for the treatment of pannus and chronic idiopathic keratoconjunctivitis sicca in dogs. It is a veterinary product produced by Intervet, which is part of Merck. Optimmune was invented by Dr. Renee Kaswan, a DVM and...
- Ophthalmic ointment (ciclosporin) for the treatment of Pannis and Keratoconjunctivitis siccaKeratoconjunctivitis siccaKeratoconjunctivitis sicca , also called keratitis sicca, xerophthalmia or dry eye syndrome is an eye disease caused by eye dryness, which, in turn, is caused by either decreased tear production or increased tear film evaporation. It is found in humans and some animals...
in dogs. - Orbax - Trade name for orbifloxacinOrbifloxacinOrbifloxacin is a fluoroquinolone antibiotic which is approved for use in dogs, marketed by Schering-Plough Animal Health....
, a fluoroquinolone. - OtomaxOtomaxOtomax is a suspension for otic use in dogs only. It is a veterinary product produced by Schering-Plough. The active ingredients of are gentamicin, betamethasone valerate and clotrimazole....
- Is indicated for the treatment of canine acute otitis externa and chronic otitis externa associated with yeastYeastYeasts are eukaryotic micro-organisms classified in the kingdom Fungi, with 1,500 species currently described estimated to be only 1% of all fungal species. Most reproduce asexually by mitosis, and many do so by an asymmetric division process called budding...
(Malassezia pachydermatis, formerly Pityrosporum canis) and/or bacteriaBacteriaBacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...
susceptible to gentamicinGentamicinGentamicin is an aminoglycoside antibiotic, used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms. However, gentamicin is not used for Neisseria gonorrhoeae, Neisseria meningitidis or Legionella pneumophila...
. It contains betamethasone valerate as an anti-inflammatory. - Banamine - A non-steroidal anti-inflammatory drug (NSAID) used in horses, cattle and swine in different parts of the world.
- Estrumate - A synthetic prostaglandinProstaglandinA prostaglandin is any member of a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring....
used in reproduction of cattle. - Trivetrin - Trimethoprin sulfate for the treatment of cattle and swine.
- Nuflor-Florfenicol-for treatment of bovine respiratory disease, foot rot and control of respiratory disease in cattle at high risk of developing bovine respiratory disease.
Exercise drug
Schering-Plough also received much publicity for a drug AICAR which mimics the effects of exercise, having especially potent effects when used alongside another drug GW1516 developed by GlaxoSmithKlineGlaxoSmithKline
GlaxoSmithKline plc is a global pharmaceutical, biologics, vaccines and consumer healthcare company headquartered in London, United Kingdom...
.
Collaborative research
In addition to internal research and development activities Schering-Plough was also involved in publicly funded collaborative research projects, with other industrial and academic partners. One example in the area of non-clinicalPre-clinical development
In drug development, pre-clinical development is a stage of research that begins before clinical trials can begin, and during which important feasibility, iterative testing and drug safety data is collected....
safety assessment was the InnoMed PredTox.
Controversy
In 2004, Schering-Plough was accused of marketing gimmicks and payoffs to doctors for prescribing the company's pharmaceutical products.Schering-Plough entered into a Consent Decree with the FDA on March 6, 2002 due to manufacturing issues with its albuterol inhaler. It was ordered to pay $500 Million US dollars to the US Treasury.