List of omics topics in biology
Encyclopedia
Inspired by the terms genome
and genomics
, other words to describe complete datasets of biological
data, mostly sets of biomolecules originating from one organism
, have been coined with the suffix -ome
and -omics. Some of these terms are related to each other in a hierarchical fashion. For example, the genome contains the ORFeome
, which gives rise to the transcriptome
, which is translated to the proteome
. Other terms are overlapping and refer to the structure and/or function of a subset of proteins (e.g. glycome
, kinome
).
Genome
In modern molecular biology and genetics, the genome is the entirety of an organism's hereditary information. It is encoded either in DNA or, for many types of virus, in RNA. The genome includes both the genes and the non-coding sequences of the DNA/RNA....
and genomics
Genomics
Genomics is a discipline in genetics concerning the study of the genomes of organisms. The field includes intensive efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping efforts. The field also includes studies of intragenomic phenomena such as heterosis,...
, other words to describe complete datasets of biological
Biology
Biology is a natural science concerned with the study of life and living organisms, including their structure, function, growth, origin, evolution, distribution, and taxonomy. Biology is a vast subject containing many subdivisions, topics, and disciplines...
data, mostly sets of biomolecules originating from one organism
Organism
In biology, an organism is any contiguous living system . In at least some form, all organisms are capable of response to stimuli, reproduction, growth and development, and maintenance of homoeostasis as a stable whole.An organism may either be unicellular or, as in the case of humans, comprise...
, have been coined with the suffix -ome
Ome
-Places:Italy* Ome, Lombardy, a comune in the Province of BresciaJapan* Ōme, Tokyo, a city in the Prefecture of Tokyo* Ōme Line, a railway in the Prefecture of TokyoUnited States* OME, the IATA and FAA code for Nome Airport, Alaska-Other uses:...
and -omics. Some of these terms are related to each other in a hierarchical fashion. For example, the genome contains the ORFeome
ORFeome
Orfeome is the complete collection of open reading frames that exists in the genome. ORFs are one of many different elements found in genomes, being part of the gene structure. The process of finding ORFs are done by computer programs such as GENSCAN....
, which gives rise to the transcriptome
Transcriptome
The transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA produced in one or a population of cells.-Scope:...
, which is translated to the proteome
Proteome
The proteome is the entire set of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the set of expressed proteins in a given type of cells or an organism at a given time under defined conditions. The term is a portmanteau of proteins and genome.The term has been...
. Other terms are overlapping and refer to the structure and/or function of a subset of proteins (e.g. glycome
Glycome
The glycome is the entire complement of sugars, whether free or present in more complex molecules, of an organism. An alternative definition is the entirety of carbohydrates in a cell. The glycome may in fact be one of the most complex entities in nature...
, kinome
Kinome
In molecular biology, the kinome of an organism is the set of protein kinases in its genome. Kinases are enzymes that catalyze phosphorylation reactions and fall into several groups and families, e.g., those that phosphorylate the amino acids serine and threonine, those that phosphorylate tyrosine...
).
List of topics
-ome | | Field of study (-omics) | | Collection of | | Parent subject | Notes | |
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Bibliome Bibliome The bibliome is the totality of biological text corpus. This term was coined around 2000 in EBI to denote the importance of biological text information. Similar terms that have been less frequently used are literaturome and textome... |
Bibliomics | Scientific bibliographic data | |||
Connectome Connectome A connectome is a comprehensive map of neural connections in the brain.The production and study of connectomes, known as connectomics, may range in scale from a detailed map of the full set of neurons and synapses within part or all of the nervous system of an organism to a macro scale description... |
Connectomics Connectomics Connectomics is a high-throughput application of neural imaging and histological techniques in order to increase the speed, efficiency, and resolution of maps of the multitude of neural connections in a nervous system... |
Structural and functional brain Brain The brain is the center of the nervous system in all vertebrate and most invertebrate animals—only a few primitive invertebrates such as sponges, jellyfish, sea squirts and starfishes do not have one. It is located in the head, usually close to primary sensory apparatus such as vision, hearing,... connectivity at different spatiotemporal scales |
Neuroscience Neuroscience Neuroscience is the scientific study of the nervous system. Traditionally, neuroscience has been seen as a branch of biology. However, it is currently an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics,... |
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Cytome Cytome Cytomes are the cellular systems, subsystems, and functional components of thebody. The cytome is the collection of the complex and dynamic cellular processes underlying physiological processes. It describes the structural and functional heterogeneity of the cellular diversity of an organism... |
Cytomics Cytomics Cytomics is the study of cell systems at a single cell level. It combines all the bioinformatic knowledge to attempt to understand the molecular architecture and functionality of the cell system... |
Cellular Cell (biology) The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos.... systems of an organism Organism In biology, an organism is any contiguous living system . In at least some form, all organisms are capable of response to stimuli, reproduction, growth and development, and maintenance of homoeostasis as a stable whole.An organism may either be unicellular or, as in the case of humans, comprise... |
Cytology Cell biology Cell biology is a scientific discipline that studies cells – their physiological properties, their structure, the organelles they contain, interactions with their environment, their life cycle, division and death. This is done both on a microscopic and molecular level... |
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Epigenome Epigenome Epigenome is equivalent to genome in epigenetics. Epigenetics is one of the current topics in cancer research drawing active research. Human tumors undergo a major disruption of DNA methylation and histone modification patterns... |
Epigenomics Epigenomics -Epigenomics:Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell... |
Epigenetic modifications Epigenetics In biology, and specifically genetics, epigenetics is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence – hence the name epi- -genetics... |
Molecular genetics Molecular genetics Molecular genetics is the field of biology and genetics that studies the structure and function of genes at a molecular level. The field studies how the genes are transferred from generation to generation. Molecular genetics employs the methods of genetics and molecular biology... |
Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, collectively known as the epigenome | |
Exposome (2005) | Exposomics | An individual's environmental exposures Gene-environment correlation Gene-environment correlation is said to occur when exposure to environmental conditions depends on an individual's genotype.-Definition:... , including in the prenatal environment |
Molecular genetics Molecular genetics Molecular genetics is the field of biology and genetics that studies the structure and function of genes at a molecular level. The field studies how the genes are transferred from generation to generation. Molecular genetics employs the methods of genetics and molecular biology... |
A proposed term and field of study of the disease-causing effects of environmental factors (the "nurture" component of "nature vs. nurture Nature versus nurture The nature versus nurture debate concerns the relative importance of an individual's innate qualities versus personal experiences The nature versus nurture debate concerns the relative importance of an individual's innate qualities ("nature," i.e. nativism, or innatism) versus personal experiences... "). |
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Exposome (2009) | Composite occupational exposures and occupational health problems | Occupational safety and health Occupational safety and health Occupational safety and health is a cross-disciplinary area concerned with protecting the safety, health and welfare of people engaged in work or employment. The goal of all occupational safety and health programs is to foster a safe work environment... |
The proposers of this term were aware of the previous term as used above but proposed to apply the term to a new field. | ||
Exome Exome The exome is the part of the genome formed by exons, coding portions of genes in the genome that are expressed, that is, provide the genetic blueprint used in the synthesis of proteins and other functional gene products... |
Exomics | Exon Exon An exon is a nucleic acid sequence that is represented in the mature form of an RNA molecule either after portions of a precursor RNA have been removed by cis-splicing or when two or more precursor RNA molecules have been ligated by trans-splicing. The mature RNA molecule can be a messenger RNA... s in a genome |
Molecular Genetics Molecular genetics Molecular genetics is the field of biology and genetics that studies the structure and function of genes at a molecular level. The field studies how the genes are transferred from generation to generation. Molecular genetics employs the methods of genetics and molecular biology... |
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Genome Genome In modern molecular biology and genetics, the genome is the entirety of an organism's hereditary information. It is encoded either in DNA or, for many types of virus, in RNA. The genome includes both the genes and the non-coding sequences of the DNA/RNA.... |
Genomics Genomics Genomics is a discipline in genetics concerning the study of the genomes of organisms. The field includes intensive efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping efforts. The field also includes studies of intragenomic phenomena such as heterosis,... (Classical genetics Classical genetics Classical genetics consists of the technique and methodologies of genetics that predate the advent of molecular biology. A key discovery of classical genetics in eukaryotes was genetic linkage... ) |
Gene Gene A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains... s (DNA sequence DNA sequence The sequence or primary structure of a nucleic acid is the composition of atoms that make up the nucleic acid and the chemical bonds that bond those atoms. Because nucleic acids, such as DNA and RNA, are unbranched polymers, this specification is equivalent to specifying the sequence of... s/Chromosome Chromosome A chromosome is an organized structure of DNA and protein found in cells. It is a single piece of coiled DNA containing many genes, regulatory elements and other nucleotide sequences. Chromosomes also contain DNA-bound proteins, which serve to package the DNA and control its functions.Chromosomes... s) |
Genetics Genetics Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms.... |
"Genome" refers to the set of all genes in an organism. However, "genome" was coined decades before it was discovered that most DNA is "non-coding" and not part of a gene; thus, "genome" originally referred to the entire collection of DNA within an organism. Today, both definitions are used, depending on the context. | |
Glycome Glycome The glycome is the entire complement of sugars, whether free or present in more complex molecules, of an organism. An alternative definition is the entirety of carbohydrates in a cell. The glycome may in fact be one of the most complex entities in nature... |
Glycomics Glycomics Glycomics is the comprehensive study of glycomes , including genetic, physiologic, pathologic, and other aspects. Glycomics "is the systematic study of all glycan structures of a given cell type or organism" and is a subset of glycobiology... |
Glycans | Glycobiology Glycobiology Defined in the broadest sense, glycobiology is the study of the structure, biosynthesis, and biology of saccharides that are widely distributed in nature... |
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Interferome Interferome Interferome is an online bioinformatics database of interferon regulated genes . These Interferon Regulated Genes are also known as Interferon Stimulated Genes . The database contains information on type I , type II and type III regulated genes and is regularly updated... |
Interferomics Interferomics Interferomics is a the study of biological events that take place post-transcriptomic pre-translatomically. It defines one of many levels in an emerging field of Life sciences known as Systems Biology.... |
Interferon Interferon Interferons are proteins made and released by host cells in response to the presence of pathogens—such as viruses, bacteria, or parasites—or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.IFNs belong to... s |
Immunology Immunology Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders ; the... |
Also a database of the same name.http://www.interferome.org/ | |
Interactome Interactome Interactome is defined as the whole set of molecular interactions in cells. It is usually displayed as a directed graph. Molecular interactions can occur between molecules belonging to different biochemical families and also within a given family... |
Interactomics Interactomics Interactomics is a discipline at the intersection of bioinformatics and biology that deals with studying both the interactions and the consequences of those interactions between and among proteins, and other molecules within a cell. The network of all such interactions is called the Interactome... |
All interactions | The term "interactomics" is generally not used. Instead, interactomes are considered the study of systems biology Systems biology Systems biology is a term used to describe a number of trends in bioscience research, and a movement which draws on those trends. Proponents describe systems biology as a biology-based inter-disciplinary study field that focuses on complex interactions in biological systems, claiming that it uses... . |
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Ionome | Ionomics Ionomics The ionome is the mineral nutrient and trace element composition of an organism, representing the inorganic component of cellular and organismal systems. Ionomics, the study of the ionome, requires application of high-throughput elemental analysis technologies, and their integration with... |
Inorganic biomolecules | Molecular Biology Molecular biology Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry... |
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Kinome Kinome In molecular biology, the kinome of an organism is the set of protein kinases in its genome. Kinases are enzymes that catalyze phosphorylation reactions and fall into several groups and families, e.g., those that phosphorylate the amino acids serine and threonine, those that phosphorylate tyrosine... |
Kinomics | Kinase Kinase In chemistry and biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substrates, a process referred to as phosphorylation. Kinases are part of the larger family of phosphotransferases... s |
Molecular Biology Molecular biology Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry... |
Proteins that add a phosphate group | |
Lipidome Lipidome The lipidome refers to the totality of lipids in cells. Lipids are one of the four major molecular components of biological organisms, along with proteins, sugars and nucleic acids. Lipidome is a term coined in the context of omics in modern biology, within the field of lipidomics. It can be... |
Lipidomics Lipidomics Lipidomics may be defined as the large-scale study of pathways and networks of cellular lipids in biological systems The word "lipidome" is used to describe the complete lipid profile within a cell, tissue or organism and is a subset of the "metabolome" which also includes the three other major... |
Lipids | Biochemistry Biochemistry Biochemistry, sometimes called biological chemistry, is the study of chemical processes in living organisms, including, but not limited to, living matter. Biochemistry governs all living organisms and living processes... |
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Mechanome Mechanome The mechanome consists of the body, or ome, of data including cell and molecular processes relating to force and mechanical systems at molecular, cellular and tissue length scales, i.e. the fundamental "machine code" structures of the cell... |
Mechanomics | The mechanical systems within an organism | |||
Metabolome Metabolome Metabolome refers to the complete set of small-molecule metabolites to be found within a biological sample, such as a single organism... |
Metabolomics Metabolomics Metabolomics is the scientific study of chemical processes involving metabolites. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite profiles... |
Metabolite Metabolite Metabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction. Alcohol is an example of a primary metabolite produced in large-scale by industrial... s |
All products of a biological reaction (including intermediates) | ||
Metagenome Metagenomics Metagenomics is the study of metagenomes, genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. Traditional microbiology and microbial genome sequencing rely upon cultivated clonal cultures... |
Metagenomics Metagenomics Metagenomics is the study of metagenomes, genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. Traditional microbiology and microbial genome sequencing rely upon cultivated clonal cultures... |
Genetic material found in an environmental sample | Molecular Biology Molecular biology Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry... |
The genetic material is assumed to contain DNA from multiple organisms and therefore multiple genomes, hence the inclusion of the prefix meta-. | |
Metallome Metallome The term metallome has been introduced by R.J.P. Williams by analogy with proteome as distribution of free metal ions in every one of cellular compartments. Subsequently, the term metallomics has been coined as the study of metallome. Szpunar defined metallomics as "comprehensive analysis of the... |
Metallomics | Metal Metal A metal , is an element, compound, or alloy that is a good conductor of both electricity and heat. Metals are usually malleable and shiny, that is they reflect most of incident light... s and metalloid Metalloid Metalloid is a term used in chemistry when classifying the chemical elements. On the basis of their general physical and chemical properties, each element can usually be classified as a metal or a nonmetal. However, some elements with intermediate or mixed properties can be harder to characterize... s |
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ORFeome ORFeome Orfeome is the complete collection of open reading frames that exists in the genome. ORFs are one of many different elements found in genomes, being part of the gene structure. The process of finding ORFs are done by computer programs such as GENSCAN.... |
ORFeomics | Open reading frame Open reading frame In molecular genetics, an open reading frame is a DNA sequence that does not contain a stop codon in a given reading frame.Normally, inserts which interrupt the reading frame of a subsequent region after the start codon cause frameshift mutation of the sequence and dislocate the sequences for stop... s (ORFs) |
Molecular Genetics Molecular genetics Molecular genetics is the field of biology and genetics that studies the structure and function of genes at a molecular level. The field studies how the genes are transferred from generation to generation. Molecular genetics employs the methods of genetics and molecular biology... |
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Organome | Organomics Organomics Organomics is the development and study of organ models and interconnected organ systems in order to better understand tissue crosstalk and how this crosstalk is used to orchestrate systemic physiology. Organome network maps can then be constructed to clarify the interaction between different... |
Organ interactions | Cell Signaling Cell signaling Cell signaling is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue... and Tissue Engineering Tissue engineering Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions... |
The study of crosstalk between organs using physiologically relevant in-vitro models | |
Pharmacogenome | Pharmacogenomics Pharmacogenomics Pharmacogenomics is the branch of pharmacology which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity... |
SNPs and their effect on pharmacokinetics Pharmacokinetics Pharmacokinetics, sometimes abbreviated as PK, is a branch of pharmacology dedicated to the determination of the fate of substances administered externally to a living organism... and pharmacodynamics Pharmacodynamics Pharmacodynamics is the study of the biochemical and physiological effects of drugs on the body or on microorganisms or parasites within or on the body and the mechanisms of drug action and the relationship between drug concentration and effect... |
Pharmacogenetics Pharmacogenetics The terms pharmacogenomics and pharmacogenetics tend to be used interchangeably, and a precise, consensus definition of either remains elusive... Genomics Genomics Genomics is a discipline in genetics concerning the study of the genomes of organisms. The field includes intensive efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping efforts. The field also includes studies of intragenomic phenomena such as heterosis,... |
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Phenome Phenome A phenome is the set of all phenotypes expressed by a cell, tissue, organ, organism, or species.Just as the genome and proteome signify all of an organism's genes and proteins, the phenome represents the sum total of its phenotypic traits. Examples of human phenotypic traits are skin color, eye... |
Phenomics Phenomics Phenomics is an area of biology concerned with the measurement of phenomes — the physical and biochemical traits of organisms — as they change in response to genetic mutation and environmental influences... |
Phenotype Phenotype A phenotype is an organism's observable characteristics or traits: such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior... s |
Genetics Genetics Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms.... |
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Physiome Physiome The physiome of an individual's or species'physiological state is the description of itsfunctional behavior. The physiome describes the physiological dynamics ofthe normal intact organism and is built upon information and... |
Physiomics Physiomics Physiomics is a systematic study of physiome in biology. Physiomics employs bioinformatics to construct networks of physiological features that are associated with genes, proteins and their networks.-External links:... |
Physiology Physiology Physiology is the science of the function of living systems. This includes how organisms, organ systems, organs, cells, and bio-molecules carry out the chemical or physical functions that exist in a living system. The highest honor awarded in physiology is the Nobel Prize in Physiology or... of an organism |
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Proteome Proteome The proteome is the entire set of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the set of expressed proteins in a given type of cells or an organism at a given time under defined conditions. The term is a portmanteau of proteins and genome.The term has been... |
Proteomics Proteomics Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term "proteomics" was first coined in 1997 to make an analogy with... |
Protein Protein Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of... s |
Molecular Biology Molecular biology Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry... |
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Regulome Regulome Regulome refers to the whole set of regulation components in a cell. Those components can be genes, mRNAs, proteins, and metabolites. The description includes the interplay of regulatory effects between these components, and their dependence on variables such as subcellular localization, tissue,... |
Regulomics | Transcription factor Transcription factor In molecular biology and genetics, a transcription factor is a protein that binds to specific DNA sequences, thereby controlling the flow of genetic information from DNA to mRNA... s and other molecules involved in the regulation of gene expression Regulation of gene expression Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.Regulation of gene expression includes the processes that cells and viruses use to regulate the way that the information in genes is turned into gene products... |
Molecular Biology Molecular biology Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry... |
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Secretome | Secretomics Secretomics Secretomics is a subset of proteomics in which all of the secreted proteins of a cell, tissue, or organism are analyzed. Secreted proteins are involved in a variety of physiological processes, including cell signaling and matrix remodeling, but are also integral to invasion and metastasis of... |
Secreted proteins | Proteomics Proteomics Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term "proteomics" was first coined in 1997 to make an analogy with... |
Subset of the proteome Proteome The proteome is the entire set of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the set of expressed proteins in a given type of cells or an organism at a given time under defined conditions. The term is a portmanteau of proteins and genome.The term has been... consisting of proteins actively exported from cells. |
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Speechome Speechome The totality of human speech components such as phoneme which is the smallest contrastive unit in the sound system of a language.Speechome is different from common biological -omes such as genome, proteome, and expressome in that it is not biological... |
Speecheomics | Influences on language acquisition Language acquisition Language acquisition is the process by which humans acquire the capacity to perceive, produce and use words to understand and communicate. This capacity involves the picking up of diverse capacities including syntax, phonetics, and an extensive vocabulary. This language might be vocal as with... |
Coined by the Human Speechome Project | ||
Transcriptome Transcriptome The transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA produced in one or a population of cells.-Scope:... |
Transcriptomics | mRNA transcripts Messenger RNA Messenger RNA is a molecule of RNA encoding a chemical "blueprint" for a protein product. mRNA is transcribed from a DNA template, and carries coding information to the sites of protein synthesis: the ribosomes. Here, the nucleic acid polymer is translated into a polymer of amino acids: a protein... |
Molecular Biology Molecular biology Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry... |
Hierarchy of topics
For the sake of clarity, some topics are listed more than once.- BibliomeBibliomeThe bibliome is the totality of biological text corpus. This term was coined around 2000 in EBI to denote the importance of biological text information. Similar terms that have been less frequently used are literaturome and textome...
- CytomeCytomeCytomes are the cellular systems, subsystems, and functional components of thebody. The cytome is the collection of the complex and dynamic cellular processes underlying physiological processes. It describes the structural and functional heterogeneity of the cellular diversity of an organism...
- Exposome
- GenomeGenomeIn modern molecular biology and genetics, the genome is the entirety of an organism's hereditary information. It is encoded either in DNA or, for many types of virus, in RNA. The genome includes both the genes and the non-coding sequences of the DNA/RNA....
- ExomeExomeThe exome is the part of the genome formed by exons, coding portions of genes in the genome that are expressed, that is, provide the genetic blueprint used in the synthesis of proteins and other functional gene products...
- ORFeomeORFeomeOrfeome is the complete collection of open reading frames that exists in the genome. ORFs are one of many different elements found in genomes, being part of the gene structure. The process of finding ORFs are done by computer programs such as GENSCAN....
- TranscriptomeTranscriptomeThe transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA produced in one or a population of cells.-Scope:...
- ProteomeProteomeThe proteome is the entire set of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the set of expressed proteins in a given type of cells or an organism at a given time under defined conditions. The term is a portmanteau of proteins and genome.The term has been...
- KinomeKinomeIn molecular biology, the kinome of an organism is the set of protein kinases in its genome. Kinases are enzymes that catalyze phosphorylation reactions and fall into several groups and families, e.g., those that phosphorylate the amino acids serine and threonine, those that phosphorylate tyrosine...
- Secretome
- Kinome
- Proteome
- Transcriptome
- ORFeome
- PharmacogenomePharmacogenomicsPharmacogenomics is the branch of pharmacology which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity...
- PhenomePhenomeA phenome is the set of all phenotypes expressed by a cell, tissue, organ, organism, or species.Just as the genome and proteome signify all of an organism's genes and proteins, the phenome represents the sum total of its phenotypic traits. Examples of human phenotypic traits are skin color, eye...
- RegulomeRegulomeRegulome refers to the whole set of regulation components in a cell. Those components can be genes, mRNAs, proteins, and metabolites. The description includes the interplay of regulatory effects between these components, and their dependence on variables such as subcellular localization, tissue,...
- Exome
- InteractomeInteractomeInteractome is defined as the whole set of molecular interactions in cells. It is usually displayed as a directed graph. Molecular interactions can occur between molecules belonging to different biochemical families and also within a given family...
- Metagenome
- Moleculome
- GlycomeGlycomeThe glycome is the entire complement of sugars, whether free or present in more complex molecules, of an organism. An alternative definition is the entirety of carbohydrates in a cell. The glycome may in fact be one of the most complex entities in nature...
- Ionome
- LipidomeLipidomeThe lipidome refers to the totality of lipids in cells. Lipids are one of the four major molecular components of biological organisms, along with proteins, sugars and nucleic acids. Lipidome is a term coined in the context of omics in modern biology, within the field of lipidomics. It can be...
- MetabolomeMetabolomeMetabolome refers to the complete set of small-molecule metabolites to be found within a biological sample, such as a single organism...
- MetallomeMetallomeThe term metallome has been introduced by R.J.P. Williams by analogy with proteome as distribution of free metal ions in every one of cellular compartments. Subsequently, the term metallomics has been coined as the study of metallome. Szpunar defined metallomics as "comprehensive analysis of the...
- ProteomeProteomeThe proteome is the entire set of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the set of expressed proteins in a given type of cells or an organism at a given time under defined conditions. The term is a portmanteau of proteins and genome.The term has been...
- Glycome
- PhysiomePhysiomeThe physiome of an individual's or species'physiological state is the description of itsfunctional behavior. The physiome describes the physiological dynamics ofthe normal intact organism and is built upon information and...
- ConnectomeConnectomeA connectome is a comprehensive map of neural connections in the brain.The production and study of connectomes, known as connectomics, may range in scale from a detailed map of the full set of neurons and synapses within part or all of the nervous system of an organism to a macro scale description...
- MechanomeMechanomeThe mechanome consists of the body, or ome, of data including cell and molecular processes relating to force and mechanical systems at molecular, cellular and tissue length scales, i.e. the fundamental "machine code" structures of the cell...
- Connectome
- MembranomeMembranomeMembranome is the set of biological membranes existing in a specific organism. The term was proposed by British biologist Thomas Cavalier-Smith to discuss epigenetics of biological membranes. The term was also used to define the entire set of membrane proteins or a combination of membrane...