Lysergamides - AbsoluteAstronomy.com

Amide

In chemistry, an amide is an organic compound that contains the functional group consisting of a carbonyl group linked to a nitrogen atom . The term refers both to a class of compounds and a functional group within those compounds. The term amide also refers to deprotonated form of ammonia or an...

s of lysergic acid

Lysergic acid

Lysergic acid, also known as D-lysergic acid and -lysergic acid, is a precursor for a wide range of ergoline alkaloids that are produced by the ergot fungus and some plants. Amides of lysergic acid, lysergamides, are widely used as pharmaceuticals and as psychedelic drugs...

are collectively known as lysergamides.
Lysergamides, tabulated by structure

Name	R1	R6	R2	R3
LSA / LAA	H	CH₃	H	H
DAM-57 DAM-57 N,N-Dimethyllysergamide is a derivative of ergine.It may cause LSD-like effects at doses of 1 milligram or more but this is disputed....	H	CH₃	CH₃	CH₃
Ergonovine Ergonovine Ergometrine , is an ergoline derivative, and one of the primary ergot and morning glory alkaloids...	H	CH₃	CH(CH₃)CH₂OH	H
Methergine	H	CH₃	CH(CH₂CH₃)CH₂OH	H
Methysergide Methysergide Methysergide is a prescription drug used for prophylaxis of migraine headaches and is sold under the brand names Sansert and Deseril in 2 mg dosages.-Pharmacology:Methysergide interacts with serotonin receptors...	CH₃	CH₃	CH(CH₂CH₃)CH₂OH	H
LAE-32 LAE-32 D-Lysergic Acid Ethylamide, is a derivative of ergine. It is reported to have some LSD-like effects but is weaker and shorter lasting, with an active dose reported to be between 0.5 and 1.5 milligrams....	H	CH₃	CH₂CH₃ Ethyl group In chemistry, an ethyl group is an alkyl substituent derived from ethane . It has the formula -C2H5 and is very often abbreviated -Et.Ethylation is the formation of a compound by introduction of the ethyl functional group, C2H5....	H
LSB Lysergic acid 2-butyl amide Lysergic acid 2-butyl amide is an analogue of LSD originally developed by Richard Pioch at Eli Lilly in the 1950s, but mostly publicised through research conducted by the team led by David E. Nichols at Purdue University...	H	CH₃	CH(CH₃)CH₂CH₃	H
LSP Lysergic acid 3-pentyl amide Lysergic acid 3-pentyl amide is an analogue of LSD originally researched by David E. Nichols and colleagues at Purdue University. It has similar binding affinity to LSD itself as both a 5-HT1A and 5-HT2A agonist, and produces similar behavioral and physiological responses in animals with only...	H	CH₃	CH(CH₂CH₃)CH₂CH₃	H
DAL	H	CH₃	H₂C=CH-CH₂ Allyl An allyl group is a substituent with the structural formula H2C=CH-CH2R, where R is the connection to the rest of the molecule. It is made up of a methylene , attached to a vinyl group . The name is derived from the Latin word for garlic, Allium sativum. Theodor Wertheim isolated an allyl...	H₂C=CH-CH₂
MIPLA Methylisopropyllysergamide Methylisopropyllysergamide is an analogue of LSD that was originally discovered by Albert Hofmann at Sandoz during the original structure-activity research into LSD. It has subsequently been investigated in more detail by the team led by David E. Nichols at Purdue University...	H	CH₃	CH(CH₃)₂ Isopropyl In organic chemistry, isopropyl is a propyl with a group attached to the secondary carbon. If viewed as a functional group an isopropyl is an organic compound with a propyl group attached at its secondary carbon.The bond is therefore on the middle carbon....	CH₃
EIPLA	H	CH₃	CH(CH₃)₂	CH₂CH₃
LAMP	H	CH₃	CH₂CH₂CH₃	CH₃
LSD LSD Lysergic acid diethylamide, abbreviated LSD or LSD-25, also known as lysergide and colloquially as acid, is a semisynthetic psychedelic drug of the ergoline family, well known for its psychological effects which can include altered thinking processes, closed and open eye visuals, synaesthesia, an... / LAD LSD Lysergic acid diethylamide, abbreviated LSD or LSD-25, also known as lysergide and colloquially as acid, is a semisynthetic psychedelic drug of the ergoline family, well known for its psychological effects which can include altered thinking processes, closed and open eye visuals, synaesthesia, an...	H	CH₃	CH₂CH₃	CH₂CH₃
ETH-LAD ETH-LAD ETH-LAD, 6-ethyl-6-nor-lysergic acid diethylamide is an analogue of LSD. It is described by Alexander Shulgin in the book TiHKAL. ETH-LAD is a hallucinogenic drug similar to LSD, and is slightly more potent than LSD itself, with an active dose reported at between 40 and 150 micrograms...	H	CH₂CH₃	CH₂CH₃	CH₂CH₃
PARGY-LAD PARGY-LAD PARGY-LAD is an analogue of LSD. It is described by Alexander Shulgin in the book TiHKAL. PARGY-LAD is a hallucinogenic drug similar to LSD, but is slightly less potent than LSD with a dose of 160 micrograms producing only mild effects, and 500 micrograms required for full activity....	H	HC≡C−CH₂ Propynyl In chemistry, propynyl is an propyl functional group bearing a triple bond. 2-Propynyl is known as propargyl group with the structure of HC≡C−CH2 and 1-propynyl group has the structure of CH3-C≡C-....	CH₂CH₃	CH₂CH₃
AL-LAD AL-LAD AL-LAD, also known as 6-allyl-6-nor-lysergic acid diethylamide, is a hallucinogenic drug and an analogue of LSD. It is described by Alexander Shulgin in the book TiHKAL ...	H	H₂C=CH-CH₂	CH₂CH₃	CH₂CH₃
PRO-LAD PRO-LAD PRO-LAD is an analogue of LSD. It is described by Alexander Shulgin in the book TiHKAL. PRO-LAD is a hallucinogenic drug similar to LSD, and is around as potent as LSD itself with an active dose reported at between 100 and 200 micrograms....	H	CH₂CH₂CH₃ Propyl In organic chemistry, propyl is a three-carbon alkyl substituent with chemical formula -C3H7. It is the substituent form of the alkane propane...	CH₂CH₃	CH₂CH₃
CYP-LAD CYP-LAD CYP-LAD, also known as 6-cyclopropyl-6-nor-lysergic acid diethylamide, is an analogue of LSD.CYP-LAD has been sold by some research chemical suppliers but might be considered illegal in some countries due to its structural similarity to LSD....	H	C₃H₅	CH₂CH₃	CH₂CH₃
BU-LAD BU-LAD BU-LAD, also known as 6-butyl-6-nor-lysergic acid diethylamide, is an analogue of LSD first made by Alexander Shulgin and reported in the book TiHKAL. BU-LAD is a hallucinogenic drug similar to LSD, but is significantly less potent than LSD, with a dose of 500 micrograms producing only mild effects....	H	CH₂CH₂CH₂CH₃ Butyl In organic chemistry, butyl is a four-carbon alkyl radical or substituent group with general chemical formula -C4H9, derived from either of the two isomers of butane....	CH₂CH₃	CH₂CH₃
ALD-52 ALD-52 ALD-52, also known as N-acetyl-LSD, is a chemical analogue of lysergic acid diethylamide . It was originally discovered by Albert Hofmann but was not widely studied until the rise in popularity of psychedelics in the 1960s.- Effects :...	COCH₃ Acetyl In organic chemistry, acetyl is a functional group, the acyl with chemical formula COCH3. It is sometimes represented by the symbol Ac . The acetyl group contains a methyl group single-bonded to a carbonyl...	CH₃	CH₂CH₃	CH₂CH₃
MLD-41 MLD-41 N1-Methyl-Lysergic Acid Diethylamide is a derivative of LSD. The 1-methyl homologue of LSD has more of somatic than sensory effect, has fewer visuals and is less well accepted than LSD, with the range of dosages being from 100 to 300 micrograms. This indicates that it is perhaps a third the...	CH₃	CH₃	CH₂CH₃	CH₂CH₃
LSM-775 LSM-775 N-Morpholinyllysergamide is a derivative of ergine. It is reported to have some LSD-like effects at doses ranging from 75 to 700 micrograms. LSM-775 is said to produce dream like states similar to DXM. Its visual component is like that of LSD, but it is said to be less intense and not as...	H	CH₃	CH₂CH₂-O-CH₂CH₂ Morpholine Morpholine is an organic chemical compound having the chemical formula O2NH. This heterocycle, pictured at right, features both amine and ether functional groups. Because of the amine, morpholine is a base; its conjugate acid is called morpholinium...
LPD-824 LPD-824 N-Pyrrolidyllysergamide is a derivative of ergine. It is reported to have some mild, short lasting LSD-like effects at a dose of 800 micrograms. The use of LPD-824 has had a minor spike between 2006 and 2007 but after this time frame, virtually no reports of LPD-824 use have been documented....	H	CH₃	CH₂CH₂ CH₂CH₂ Pyrrolidine Pyrrolidine, also known as tetrahydropyrrole, is an organic compound with the molecular formula C4H9N. It is a cyclic secondary amine with a five-membered heterocycle containing four carbon atoms and one nitrogen atom...
LSD-Pip LSD-Pip LSD-Pip is a compound from the ergoline family, related to LSD but with the N,N-diethyl substitution replaced by a piperidine group. It is more potent than the corresponding pyrrolidine and morpholine analogues , but is still several times less potent than LSD as a 5-HT2A agonist...	H	CH₃	CH₂CH₂ CH₂CH₂CH₂ Piperidine Piperidine is an organic compound with the molecular formula 5NH. This heterocyclic amine consists of a six-membered ring containing five methylene units and one nitrogen atom...
LA-SS-Az Lysergic acid 2,4-dimethylazetidide Lysergic acid 2,4-dimethylazetidide is an analogue of LSD developed by the team led by David E. Nichols at Purdue University. It was developed as a rigid analogue of LSD with the diethylamide group constrained into an azetidine ring in order to map the binding site at the 5-HT2A receptor...	H	CH₃	CH₂(CHCH₃)₂CH₂

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