RNA recognition motif
Encyclopedia
RNA recognition motif, RNP-1 is a putative RNA
-binding domain
of about 90 amino acids that are known to bind single-stranded RNAs. It was found in many eukaryotic proteins.
The largest group of single strand RNA-binding proteins is the eukaryotic RNA recognition motif (RRM) family that contains an eight amino acid RNP-1 consensus sequence.
RRM proteins have a variety of RNA binding preferences and functions, and include heterogeneous nuclear ribonucleoproteins (hnRNPs), proteins implicated in regulation of alternative splicing
(SR, U2AF2
, Sxl), protein components of small nuclear ribonucleoproteins (U1 and U2 snRNP
s), and proteins that regulate RNA stability and translation (PABP, La, Hu). The RRM in heterodimeric splicing factor U2 snRNP auxiliary factor
appears to have two RRM-like domains with specialised features for protein recognition. The motif also appears in a few single stranded DNA binding proteins.
The typical RRM consists of four anti-parallel beta-strands and two alpha-helices arranged in a beta-alpha-beta-beta-alpha-beta fold with side chains that stack with RNA bases. Specificity of RNA binding is determined by multiple contacts with surrounding amino acids. A third helix is present during RNA binding in some cases. The RRM is reviewed in a number of publications.
; BOLL
; BRUNOL4
; BRUNOL5; BRUNOL6; CCBL2; CGI-96;
CIRBP
; CNOT4; CPEB2; CPEB3; CPEB4; CPSF7; CSTF2
; CSTF2T
;
CUGBP1
; CUGBP2
; D10S102; DAZ1
; DAZ2
; DAZ3
; DAZ4; DAZAP1;
DAZL
; DNAJC17; DND1; EIF3S4; EIF3S9; EIF4B
; EIF4H
; ELAVL1
;
ELAVL2
; ELAVL3
; ELAVL4
; ENOX1; ENOX2
; EWSR1; FUS
; FUSIP1
;
G3BP; G3BP1
; G3BP2
; GRSF1; HNRNPL
; HNRPA0; HNRPA1
; HNRPA2B1
;
HNRPA3
; HNRPAB
; HNRPC; HNRPCL1; HNRPD
; HNRPDL
; HNRPF
; HNRPH1
;
HNRPH2
; HNRPH3
; HNRPL; HNRPLL; HNRPM; HNRPR; HRNBP1; HSU53209;
HTATSF1
; IGF2BP1
; IGF2BP2
; IGF2BP3
; LARP7; MKI67IP
; MSI1
; MSI2; MSSP-2;
MTHFSD; MYEF2; NCBP2; NCL
; NOL8
; NONO
; ORF
; P14
;
PABPC1
; PABPC1L; PABPC3
; PABPC4
; PABPC5; PABPN1
; POLDIP3
; PPARGC1;
PPARGC1A
; PPARGC1B
; PPIE; PPIL4
; PPRC1
; PSPC1; PTBP1
; PTBP2
;
PUF60
; RALY
; RALYL
; RAVER1
; RAVER2; RBM10
; RBM11
; RBM12
;
RBM12B; RBM14
; RBM15
; RBM15B; RBM16; RBM17
; RBM18; RBM19
;
RBM22
; RBM23
; RBM24; RBM25
; RBM26
; RBM27; RBM28
; RBM3
;
RBM32B; RBM33
; RBM34
; RBM35A; RBM35B; RBM38; RBM39
; RBM4
;
RBM41; RBM42; RBM44; RBM45; RBM46; RBM47; RBM4B; RBM5
;
RBM7
; RBM8A
; RBM9
; RBMS1
; RBMS2; RBMS3; RBMX
; RBMX2;
RBMXL2; RBMY1A1
; RBMY1B; RBMY1E; RBMY1F; RBMY2FP; RBPMS
; RBPMS2;
RDBP
; RNPC3; RNPC4; RNPS1
; ROD1; SAFB
; SAFB2
; SART3
;
SETD1A; SF3B14
; SF3B4
; SFPQ
; SFRS1; SFRS10
; SFRS11
; SFRS12
;
SFRS15; SFRS2
; SFRS2B; SFRS3
; SFRS4
; SFRS5
; SFRS6
; SFRS7
;
SFRS9
; SLIRP
; SLTM; SNRP70
; SNRPA; SNRPB2
; SPEN
; SR140;
SRRP35; SSB
; SYNCRIP
; TAF15
; TARDBP
; THOC4
; TIA1
; TIAL1
;
TNRC4; TNRC6C; TRA2A
; TRSPAP1; TUT1; U1SNRNPBP; U2AF1; U2AF2
;
UHMK1
; ZCRB1; ZNF638
; ZRSR1
; ZRSR2
; eIF4B
;
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....
-binding domain
Protein domain
A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural...
of about 90 amino acids that are known to bind single-stranded RNAs. It was found in many eukaryotic proteins.
The largest group of single strand RNA-binding proteins is the eukaryotic RNA recognition motif (RRM) family that contains an eight amino acid RNP-1 consensus sequence.
RRM proteins have a variety of RNA binding preferences and functions, and include heterogeneous nuclear ribonucleoproteins (hnRNPs), proteins implicated in regulation of alternative splicing
Alternative splicing
Alternative splicing is a process by which the exons of the RNA produced by transcription of a gene are reconnected in multiple ways during RNA splicing...
(SR, U2AF2
U2AF2
Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the U2AF2 gene.-Interactions:U2AF2 has been shown to interact with WT1, PUF60, SFRS2IP, SRPK2, SF1, U2 small nuclear RNA auxiliary factor 1 and SFRS11.-References:...
, Sxl), protein components of small nuclear ribonucleoproteins (U1 and U2 snRNP
SnRNP
snRNPs , or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs...
s), and proteins that regulate RNA stability and translation (PABP, La, Hu). The RRM in heterodimeric splicing factor U2 snRNP auxiliary factor
U2 small nuclear RNA auxiliary factor 1
Splicing factor U2AF 35 kDa subunit is a protein that in humans is encoded by the U2AF1 gene.-Interactions:U2 small nuclear RNA auxiliary factor 1 has been shown to interact with RP9, U2AF2, NXF1, ASF/SF2 and ZRANB2.-Further reading:...
appears to have two RRM-like domains with specialised features for protein recognition. The motif also appears in a few single stranded DNA binding proteins.
The typical RRM consists of four anti-parallel beta-strands and two alpha-helices arranged in a beta-alpha-beta-beta-alpha-beta fold with side chains that stack with RNA bases. Specificity of RNA binding is determined by multiple contacts with surrounding amino acids. A third helix is present during RNA binding in some cases. The RRM is reviewed in a number of publications.
Human proteins containing this domain
A2BP1; ACFACF (gene)
APOBEC1 complementation factor is a protein that in humans is encoded by the A1CF gene.-Interactions:ACF has been shown to interact with CUGBP2, SYNCRIP and APOBEC1.-Further reading:...
; BOLL
BOLL
Protein boule-like is a protein that in humans is encoded by the BOLL gene.- Function :This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ or DAZL...
; BRUNOL4
BRUNOL4
CUG-BP- and ETR-3-like factor 4 is a protein that in humans is encoded by the BRUNOL4 gene.-Further reading:...
; BRUNOL5; BRUNOL6; CCBL2; CGI-96;
CIRBP
CIRBP
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene.-Further reading:...
; CNOT4; CPEB2; CPEB3; CPEB4; CPSF7; CSTF2
CSTF2
Cleavage stimulation factor 64 kDa subunit is a protein that in humans is encoded by the CSTF2 gene.-Interactions:CSTF2 has been shown to interact with CSTF3, SUB1, SYMPK, BARD1 and BRCA1.-Further reading:...
; CSTF2T
CSTF2T
Cleavage stimulation factor 64 kDa subunit, tau variant is a protein that in humans is encoded by the CSTF2T gene.-Further reading:...
;
CUGBP1
CUGBP1
CUG triplet repeat, RNA binding protein 1, also known as CUGBP1, is a protein which in humans is encoded by the CUGBP1 gene.-Function:...
; CUGBP2
CUGBP2
CUG-BP- and ETR-3-like factor 2 is a protein that in humans is encoded by the CUGBP2 gene.-Interactions:CUGBP2 has been shown to interact with ACF.-Further reading:...
; D10S102; DAZ1
DAZ1
Deleted in azoospermia 1, also known as DAZ1, is a protein which in humans is encoded by the DAZ1 gene.- Function :This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor . Its expression is restricted to pre-meiotic germ cells, particularly in...
; DAZ2
DAZ2
Deleted in azoospermia protein 2 is a protein that in humans is encoded by the DAZ2 gene.-Further reading:...
; DAZ3
DAZ3
Deleted in azoospermia protein 3 is a protein that in humans is encoded by the DAZ3 gene.-Further reading:...
; DAZ4; DAZAP1;
DAZL
DAZL
Deleted in azoospermia-like is a protein that in humans is encoded by the DAZL gene.-Further reading:...
; DNAJC17; DND1; EIF3S4; EIF3S9; EIF4B
EIF4B
Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.-External links:* from Nature Reviews Microbiology. A good image and overview of the function of initiation factors-Further reading:...
; EIF4H
EIF4H
Eukaryotic translation initiation factor 4H is a protein that in humans is encoded by the EIF4H gene.EIF4H appears analogous to drr-2 in C. elegans which regulates the mTOR pathway and affects longevity.-Further reading:...
; ELAVL1
ELAVL1
ELAV-like protein 1 or HuR is a protein that in humans is encoded by the ELAVL1 gene.-Further reading:...
;
ELAVL2
ELAVL2
ELAV-like protein 2 is a protein that in humans is encoded by the ELAVL2 gene.-Further reading:...
; ELAVL3
ELAVL3
ELAV-like protein 3 is a protein that in humans is encoded by the ELAVL3 gene.-Further reading:...
; ELAVL4
ELAVL4
HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene.The HuD/ELAVL4 protein is an RNA-binding protein....
; ENOX1; ENOX2
ENOX2
Ecto-NOX disulfide-thiol exchanger 2 is a protein that in humans is encoded by the ENOX2 gene.-Further reading:...
; EWSR1; FUS
FUS
RNA-binding protein FUS is a protein that in humans is encoded by the FUS gene.- Function :The N-terminal end of FUS appears to be involved in transcriptional activation, while the C-terminal end is involved in protein and RNA binding...
; FUSIP1
FUSIP1
FUS-interacting serine-arginine-rich protein 1 is a protein that in humans is encoded by the SFRS13A gene.-Further reading:...
;
G3BP; G3BP1
G3BP1
Ras GTPase-activating protein-binding protein 1 is an enzyme that in humans is encoded by the G3BP1 gene.-Interactions:G3BP1 has been shown to interact with USP10.It also interacts with SND1[5].-References:...
; G3BP2
G3BP2
Ras GTPase-activating protein-binding protein 2 is an enzyme that in humans is encoded by the G3BP2 gene.-Further reading:...
; GRSF1; HNRNPL
HNRNPL
Heterogeneous nuclear ribonucleoprotein L is a protein that in humans is encoded by the HNRNPL gene.-Interactions:HNRNPL has been shown to interact with PCBP2, HNRPK and PTBP1.-Further reading:...
; HNRPA0; HNRPA1
HNRPA1
Heterogeneous nuclear ribonucleoprotein A1 is a protein that in humans is encoded by the HNRNPA1 gene.-Interactions:Heterogeneous nuclear ribonucleoprotein A1 has been shown to interact with BAT2, Flap structure-specific endonuclease 1 and IκBα....
; HNRPA2B1
HNRPA2B1
Heterogeneous nuclear ribonucleoproteins A2/B1 is a protein that in humans is encoded by the HNRNPA2B1 gene.HnRNPA2B1 is an autoantigen in autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and mixed connective tissue disease...
;
HNRPA3
HNRPA3
Heterogeneous nuclear ribonucleoprotein A3 is a protein that in humans is encoded by the HNRNPA3 gene.-Further reading:...
; HNRPAB
HNRPAB
Heterogeneous nuclear ribonucleoprotein A/B, also known as HNRPAB, is a protein which in humans is encoded by the HNRPAB gene. Although this gene is named HNRNPAB in reference to its first cloning as an RNA binding protein with similarity to HNRNP A and HNRNP B, it is not a member of the HNRNP A/B...
; HNRPC; HNRPCL1; HNRPD
HNRPD
Heterogeneous nuclear ribonucleoprotein D0 is a protein that in humans is encoded by the HNRNPD gene.-Interactions:HNRPD has been shown to interact with SAFB and Hsp27.-Further reading:...
; HNRPDL
HNRPDL
Heterogeneous nuclear ribonucleoprotein D-like, also known as HNRPDL, is a protein which in humans is encoded by the HNRPDL gene.- Function :...
; HNRPF
HNRPF
Heterogeneous nuclear ribonucleoprotein F is a protein that in humans is encoded by the HNRNPF gene.-Further reading:...
; HNRPH1
HNRPH1
Heterogeneous nuclear ribonucleoprotein H is a protein that in humans is encoded by the HNRNPH1 gene.-Further reading:...
;
HNRPH2
HNRPH2
Heterogeneous nuclear ribonucleoprotein H2 is a protein that in humans is encoded by the HNRNPH2 gene.-Further reading:...
; HNRPH3
HNRPH3
Heterogeneous nuclear ribonucleoprotein H3 is a protein that in humans is encoded by the HNRNPH3 gene.-Further reading:...
; HNRPL; HNRPLL; HNRPM; HNRPR; HRNBP1; HSU53209;
HTATSF1
HTATSF1
HIV Tat-specific factor 1 is a protein that in humans is encoded by the HTATSF1 gene.-Interactions:HTATSF1 has been shown to interact with SUPT5H and GTF2F2.-Further reading:...
; IGF2BP1
IGF2BP1
Insulin-like growth factor 2 mRNA-binding protein 1 is a protein that in humans is encoded by the IGF2BP1 gene.-Further reading:...
; IGF2BP2
IGF2BP2
Insulin-like growth factor 2 mRNA-binding protein 2 is a protein that in humans is encoded by the IGF2BP2 gene.-Further reading:...
; IGF2BP3
IGF2BP3
Insulin-like growth factor 2 mRNA-binding protein 3 is a protein that in humans is encoded by the IGF2BP3 gene.-Further reading:...
; LARP7; MKI67IP
MKI67IP
MKI67 FHA domain-interacting nucleolar phosphoprotein contains an RNA recognition motif near to the N-terminus and a FHA Ki67 binding domain near to the C-terminus. There are two conserved sequence motifs within the FHA Ki67 binding domain: TPVCTP and LERRKS, this domain binds to the...
; MSI1
MSI1
RNA-binding protein Musashi homolog 1 is a protein that in humans is encoded by the MSI1 gene.-Further reading:...
; MSI2; MSSP-2;
MTHFSD; MYEF2; NCBP2; NCL
NCL
NCL may refer to:* Norwegian Cruise Line, a cruise ship company* National Conference League, a rugby league competition played in the UK* National Consumers League, formed in the 1890s for women's suffrage, protection of female and child laborers, eliminations of health hazards* New Caledonia, a...
; NOL8
NOL8
Nucleolar protein 8 is a protein that in humans is encoded by the NOL8 gene.-Interactions:NOL8 has been shown to interact with RRAGA and NIP7.-Further reading:...
; NONO
NONO
Non-POU domain-containing octamer-binding protein is a protein that in humans is encoded by the NONO gene.-Interactions:NONO has been shown to interact with SFPQ, SPI1 and Androgen receptor.-Further reading:...
; ORF
ORF
ORF may refer to:* ORF , the Austrian public service broadcaster.* Open reading frame, a portion of the genome.* The IATA airport code for Norfolk International Airport in Norfolk, Virginia.* ORF format , Olympus raw image file format....
; P14
P14
P14, P-14 or P.14 may refer to:* Pattern 1914 Enfield, a service rifle used by the British Army during World War I* P-14 radar, a radar used by the Soviet military* P14 , a tax form in the UK* LSWR P14 class, a type of locomotive...
;
PABPC1
PABPC1
Polyadenylate-binding protein 1 is a protein that in humans is encoded by the PABPC1 gene.-Interactions:PABPC1 has been shown to interact with ANAPC5, GSPT2, CNOT7, PAIP1, Eukaryotic translation initiation factor 4 gamma, EIF4G3 and PAIP2....
; PABPC1L; PABPC3
PABPC3
Polyadenylate-binding protein 3 is a protein that in humans is encoded by the PABPC3 gene.-Further reading:...
; PABPC4
PABPC4
Polyadenylate-binding protein 4 is a protein that in humans is encoded by the PABPC4 gene.-Further reading:...
; PABPC5; PABPN1
PABPN1
Polyadenylate-binding protein 2 also known as polyadenylate-binding nuclear protein 1 is a protein that in humans is encoded by the PABPN1 gene.- Function :...
; POLDIP3
POLDIP3
Polymerase delta-interacting protein 3 is an enzyme that in humans is encoded by the POLDIP3 gene.-Interactions:POLDIP3 has been shown to interact with P70-S6 Kinase 1.-Further reading:...
; PPARGC1;
PPARGC1A
PPARGC1A
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha is a protein that in humans is encoded by the PPARGC1A gene....
; PPARGC1B
PPARGC1B
Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene.-Further reading:...
; PPIE; PPIL4
PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4 is an enzyme that in humans is encoded by the PPIL4 gene.-Further reading:...
; PPRC1
PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 is a protein that in humans is encoded by the PPRC1 gene.-Further reading:...
; PSPC1; PTBP1
PTBP1
Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene.-Interactions:PTBP1 has been shown to interact with HNRPK, PCBP2, SFPQ and HNRNPL.This gene is targeted by the microRNA miR-124...
; PTBP2
PTBP2
Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.- Function :...
;
PUF60
PUF60
Poly-binding-splicing factor PUF60 is a protein that in humans is encoded by the PUF60 gene.-Further reading:...
; RALY
RALY
RNA-binding protein Raly is a protein that in humans is encoded by the RALY gene.-Further reading:...
; RALYL
RALYL
RNA-binding Raly-like protein is a protein that in humans is encoded by the RALYL gene.-Further reading:...
; RAVER1
RAVER1
Ribonucleoprotein, PTB-binding 1 , is a human gene.-Further reading:...
; RAVER2; RBM10
RBM10
RNA-binding protein 10 is a protein that in humans is encoded by the RBM10 gene.-Further reading:...
; RBM11
RBM11
Putative RNA-binding protein 11 is a protein that in humans is encoded by the RBM11 gene.-Further reading:...
; RBM12
RBM12
RNA-binding protein 12 is a protein that in humans is encoded by the RBM12 gene.-Further reading:...
;
RBM12B; RBM14
RBM14
RNA-binding protein 14 is a protein that in humans is encoded by the RBM14 gene.-Further reading:...
; RBM15
RBM15
Putative RNA-binding protein 15 is a protein that in humans is encoded by the RBM15 gene.-Further reading:...
; RBM15B; RBM16; RBM17
RBM17
Splicing factor 45 is a protein that in humans is encoded by the RBM17 gene.-Further reading:...
; RBM18; RBM19
RBM19
Probable RNA-binding protein 19 is a protein that in humans is encoded by the RBM19 gene.-Further reading:...
;
RBM22
RBM22
Pre-mRNA-splicing factor RBM22 is a protein that in humans is encoded by the RBM22 gene.-Further reading:...
; RBM23
RBM23
Probable RNA-binding protein 23 is a protein that in humans is encoded by the RBM23 gene.-Further reading:...
; RBM24; RBM25
RBM25
RNA-binding protein 25 is a protein that in humans is encoded by the RBM25 gene.-Further reading:...
; RBM26
RBM26
RNA-binding protein 26 is a protein that in humans is encoded by the RBM26 gene.-Further reading:...
; RBM27; RBM28
RBM28
RNA-binding protein 28 is a protein that in humans is encoded by the RBM28 gene.-Further reading:...
; RBM3
RBM3
Putative RNA-binding protein 3 is a protein that in humans is encoded by the RBM3 gene.-Further reading:...
;
RBM32B; RBM33
RBM33
RNA-binding protein 33 is a protein that in humans is encoded by the RBM33 gene.-Further reading:...
; RBM34
RBM34
RNA-binding protein 34 is a protein that in humans is encoded by the RBM34 gene.-Further reading:...
; RBM35A; RBM35B; RBM38; RBM39
RBM39
RNA-binding protein 39 is a protein that in humans is encoded by the RBM39 gene.-Interactions:RBM39 has been shown to interact with Estrogen receptor alpha, Estrogen receptor beta and C-jun.-Further reading:...
; RBM4
RBM4
RNA-binding protein 4 is a protein that in humans is encoded by the RBM4 gene.-Further reading:...
;
RBM41; RBM42; RBM44; RBM45; RBM46; RBM47; RBM4B; RBM5
RBM5
RNA-binding protein 5 is a protein that in humans is encoded by the RBM5 gene.-Further reading:...
;
RBM7
RBM7
RNA-binding protein 7 is a protein that in humans is encoded by the RBM7 gene.-Interactions:RBM7 has been shown to interact with SF3B2 and SFRS3.-Further reading:...
; RBM8A
RBM8A
RNA-binding protein 8A is a protein that in humans is encoded by the RBM8A gene.-Interactions:RBM8A has been shown to interact with IPO13, MAGOH and UPF3A.-Related gene problems:*TAR syndrome*1q21.1 deletion syndrome*1q21.1 duplication syndrome...
; RBM9
RBM9
RNA binding motif protein 9, also known as RBM9 or FOX-2, is a protein which in humans is encoded by the RBM9 gene.- Function :...
; RBMS1
RBMS1
RNA-binding motif, single-stranded-interacting protein 1 is a protein that in humans is encoded by the RBMS1 gene.-Interactions:RBMS1 has been shown to interact with Polymerase , alpha 1.-Further reading:...
; RBMS2; RBMS3; RBMX
RBMX
Heterogeneous nuclear ribonucleoprotein G is a protein that in humans is encoded by the RBMX gene.-Interactions:RBMX has been shown to interact with SFRS10 and CDC5L.-Further reading:...
; RBMX2;
RBMXL2; RBMY1A1
RBMY1A1
RNA-binding motif protein, Y chromosome, family 1 member A1/C is a protein that in humans is encoded by the RBMY1A1 gene.-Further reading:...
; RBMY1B; RBMY1E; RBMY1F; RBMY2FP; RBPMS
RBPMS
RNA-binding protein with multiple splicing is a protein that in humans is encoded by the RBPMS gene.-Further reading:...
; RBPMS2;
RDBP
RDBP
Negative elongation factor E is a protein that in humans is encoded by the RDBP gene.-Interactions:RDBP has been shown to interact with TH1L, WHSC2 and Cofactor of BRCA1.-External links:...
; RNPC3; RNPC4; RNPS1
RNPS1
RNA-binding protein with serine-rich domain 1 is a protein that in humans is encoded by the RNPS1 gene.-Interactions:RNPS1 has been shown to interact with SART3 and Pinin.-Further reading:...
; ROD1; SAFB
SAFB
Scaffold attachment factor B, also known as SAFB, is a gene with homologs that have been studied in humans and mice.-Interactions:SAFB has been shown to interact with Estrogen receptor alpha, TAF15, SAFB2 and HNRPD.-Further reading:...
; SAFB2
SAFB2
Scaffold attachment factor B2 is a protein that in humans is encoded by the SAFB2 gene.-Interactions:SAFB2 has been shown to interact with Estrogen receptor alpha and SAFB.-Further reading:...
; SART3
SART3
Squamous cell carcinoma antigen recognized by T-cells 3 is a protein that in humans is encoded by the SART3 gene.The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen...
;
SETD1A; SF3B14
SF3B14
Splicing factor 3B, 14 kDa subunit, also known as SF3B14, is a human gene.-Further reading:...
; SF3B4
SF3B4
Splicing factor 3B subunit 4 is a protein that in humans is encoded by the SF3B4 gene.-Interactions:SF3B4 has been shown to interact with CDC5L, BMPR1A and SF3B2.-Further reading:...
; SFPQ
SFPQ
Splicing factor, proline- and glutamine-rich is a protein that in humans is encoded by the SFPQ gene.-Interactions:SFPQ has been shown to interact with PTBP1, NONO, CDC5L and Ubiquitin C.-Further reading:...
; SFRS1; SFRS10
SFRS10
Transformer-2 protein homolog beta, also known as TRA2B previously known as splicing factor, arginine/serine-rich 10 , is a protein that in humans is encoded by the TRA2B gene....
; SFRS11
SFRS11
Splicing factor, arginine/serine-rich 11 is a protein that in humans is encoded by the SFRS11 gene.-Further reading:...
; SFRS12
SFRS12
Splicing factor, arginine/serine-rich 12 is a protein that in humans is encoded by the SFRS12 gene.-Further reading:...
;
SFRS15; SFRS2
SFRS2
Splicing factor, arginine/serine-rich 2 is a protein that in humans is encoded by the SFRS2 gene.-Interactions:SFRS2 has been shown to interact with CDC5L and ASF/SF2.-Further reading:...
; SFRS2B; SFRS3
SFRS3
Splicing factor, arginine/serine-rich 3 is a protein that in humans is encoded by the SFRS3 gene.-Browser View:-Further reading:...
; SFRS4
SFRS4
Splicing factor, arginine/serine-rich 4 is a protein that in humans is encoded by the SFRS4 gene.-Further reading:...
; SFRS5
SFRS5
Splicing factor, arginine/serine-rich 5 is a protein that in humans is encoded by the SFRS5 gene.-Further reading:...
; SFRS6
SFRS6
Splicing factor, arginine/serine-rich 6 is a protein that in humans is encoded by the SFRS6 gene.-Further reading:...
; SFRS7
SFRS7
Serine/arginine-rich splicing factor 7 also known as splicing factor, arginine/serine-rich 7 or splicing factor 9G8 is a protein that in humans is encoded by the SRSF7 gene.- Function :...
;
SFRS9
SFRS9
Splicing factor, arginine/serine-rich 9, also known as SFRS9, is a human gene encoding an SR protein involved in splice site selection in alternative splicing.-Interactions:SFRS9 has been shown to interact with Y box binding protein 1 and NOL3....
; SLIRP
Slirp
Slirp is a software program that emulates a PPP, SLIP, or CSLIP connection to the Internet via a shell account. It is largely obsolete for its original purpose, as dedicated dial-up PPP connections and broadband Internet access have in turn become widely available and inexpensive...
; SLTM; SNRP70
SNRP70
snRNP70 also known as U1 small nuclear ribonucleoprotein 70 kDa is a protein that in humans is encoded by the SNRNP70 gene. snRNP70 is a small nuclear ribonucleoprotein that associates with U1 spliceosomal RNA, forming part of the spliceosome....
; SNRPA; SNRPB2
SNRPB2
U2 small nuclear ribonucleoprotein B is a protein that in humans is encoded by the SNRPB2 gene.-Further reading:...
; SPEN
SPEN
Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.-Interactions:SPEN has been shown to interact with HDAC1, SRA1 and Nuclear receptor co-repressor 2.-Further reading:...
; SR140;
SRRP35; SSB
SSB
- Organizations :* '* Societas Sanctae Birgittae, the Society of Saint Bridget* Society of the Sisters of Bethany, an Anglican religious order* Statistics Norway, , Norwegian government statistics bureau...
; SYNCRIP
SYNCRIP
Heterogeneous nuclear ribonucleoprotein Q is a protein that in humans is encoded by the SYNCRIP gene.-Interactions:SYNCRIP has been shown to interact with ACF, APOBEC1, SYT7 and SYT9.-Further reading:...
; TAF15
TAF15
TATA-binding protein-associated factor 2N is a protein that in humans is encoded by the TAF15 gene.-Interactions:TAF15 has been shown to interact with TAF7, POLR2C, TAF5, POLR2E, TAF13, SAFB, TAF11, TATA binding protein and POLR2G.-Further reading:...
; TARDBP
TARDBP
TAR DNA-binding protein 43 , is a cellular protein which in humans is encoded by the TARDBP gene.- Discovery :TARDBP was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It was also reported to regulate alternate...
; THOC4
THOC4
THO complex subunit 4 is a protein that in humans is encoded by the THOC4 gene.-Further reading:...
; TIA1
TIA1
TIA1 is a poly-binding protein. It is associated with programmed cell death and regulates alternative splicing of the gene encoding the Fas receptor, an apoptosis-promoting protein....
; TIAL1
TIAL1
Nucleolysin TIAR is a protein that in humans is encoded by the TIAL1 gene.-Further reading:...
;
TNRC4; TNRC6C; TRA2A
TRA2A
Transformer-2 protein homolog alpha is a protein that in humans is encoded by the TRA2A gene.-Further reading:...
; TRSPAP1; TUT1; U1SNRNPBP; U2AF1; U2AF2
U2AF2
Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the U2AF2 gene.-Interactions:U2AF2 has been shown to interact with WT1, PUF60, SFRS2IP, SRPK2, SF1, U2 small nuclear RNA auxiliary factor 1 and SFRS11.-References:...
;
UHMK1
UHMK1
U2AF homology motif kinase 1, also known as UHMK1, is a protein which in humans is encoded by the UHMK1 gene.-Function:UHMK1 is a kinase enzyme which phosphorylates the protein stathmin and has an RNA recognition motif of unknown function....
; ZCRB1; ZNF638
ZNF638
Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene....
; ZRSR1
ZRSR1
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 is a protein that in humans is encoded by the ZRSR1 gene.-Further reading:...
; ZRSR2
ZRSR2
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 is a protein that in humans is encoded by the ZRSR2 gene.-Further reading:...
; eIF4B
EIF4B
Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.-External links:* from Nature Reviews Microbiology. A good image and overview of the function of initiation factors-Further reading:...
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