Many conditions affect the human integumentary system

Integumentary system

The integumentary system is the organ system that protects the body from damage, comprising the skin and its appendages...

—the organ system covering the entire surface of the body

Human body

The human body is the entire structure of a human organism, and consists of a head, neck, torso, two arms and two legs.By the time the human reaches adulthood, the body consists of close to 100 trillion cells, the basic unit of life...

 and is composed of skin

Human skin

The human skin is the outer covering of the body. In humans, it is the largest organ of the integumentary system. The skin has multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments and internal organs. Human skin is similar to that of most other mammals,...

, hair

Hair

Hair is a filamentous biomaterial, that grows from follicles found in the dermis. Found exclusively in mammals, hair is one of the defining characteristics of the mammalian class....

, nails

Nail (anatomy)

A nail is a horn-like envelope covering the dorsal aspect of the terminal phalanges of fingers and toes in humans, most non-human primates, and a few other mammals. Nails are similar to claws, which are found on numerous other animals....

, and related muscle

Muscle

Muscle is a contractile tissue of animals and is derived from the mesodermal layer of embryonic germ cells. Muscle cells contain contractile filaments that move past each other and change the size of the cell. They are classified as skeletal, cardiac, or smooth muscles. Their function is to...

 and glands. The major function of this system is as a barrier against the external environment. The skin weighs an average of four kilograms, covers an area of two square meters, and is made of three distinct layers: the epidermis, dermis

Dermis

The dermis is a layer of skin between the epidermis and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis...

, and subcutaneous tissue

Subcutaneous tissue

The hypodermis, also called the hypoderm, subcutaneous tissue, or superficial fascia is the lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages...

. There are two main types of human skin: glabrous skin, the nonhairy skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. Within the latter type, there are hairs in structures called pilosebaceous unit

Pilosebaceous unit

The Pilosebaceous unit is an epidermal invagination found on most surfaces of the human body....

s, each with hair follicle

Hair follicle

A hair follicle is a skin organ that produces hair. Hair production occurs in phases, including a growth phase , and cessation phase , and a rest phase . Stem cells are principally responsible for the production of hair....

, sebaceous gland

Sebaceous gland

The sebaceous glands are microscopic glands in the skin that secrete an oily/waxy matter, called sebum, to lubricate and waterproof the skin and hair of mammals...

, and associated arrector pili muscle. In the embryo

Embryology

Embryology is a science which is about the development of an embryo from the fertilization of the ovum to the fetus stage...

, the epidermis, hair, and glands form from the ectoderm

Ectoderm

The "ectoderm" is one of the three primary germ cell layers in the very early embryo. The other two layers are the mesoderm and endoderm , with the ectoderm as the most exterior layer...

, which is chemically influenced by the underlying mesoderm

Mesoderm

In all bilaterian animals, the mesoderm is one of the three primary germ cell layers in the very early embryo. The other two layers are the ectoderm and endoderm , with the mesoderm as the middle layer between them.The mesoderm forms mesenchyme , mesothelium, non-epithelial blood corpuscles and...

 that forms the dermis and subcutaneous tissues.

The epidermis is the most superficial layer of skin, a squamous epithelium

Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. Epithelial tissues line the cavities and surfaces of structures throughout the body, and also form many glands. Functions of epithelial cells include secretion, selective...

 with several strata

Stratum

In geology and related fields, a stratum is a layer of sedimentary rock or soil with internally consistent characteristics that distinguish it from other layers...

: the stratum corneum

Stratum corneum

The stratum corneum is the outermost layer of the epidermis, consisting of dead cells that lack nuclei and organelles. The purpose of the stratum corneum is to form a barrier to protect underlying tissue from infection, dehydration, chemicals and mechanical stress...

, stratum lucidum

Stratum lucidum

The stratum lucidum is a thin, clear layer of dead skin cells in the epidermis named for its translucent appearance under a microscope...

, stratum granulosum

Stratum granulosum

The stratum granulosum is a thin layer of cells in the epidermis. Keratinocytes migrating from the underlying stratum spinosum become known as granular cells in this layer...

, stratum spinosum

Stratum spinosum

The stratum spinosum is a layer of the epidermis found between the stratum granulosum and stratum basale. This layer is also referred to as the "spinous" or "prickle-cell" layer. This appearance is due to desmosomal connections of adjacent cells. Keratinization begins in the stratum spinosum....

, and stratum basale

Stratum germinativum

The stratum basale is the deepest layer of the five layers of the epidermis, which is the outer covering of skin in mammals. The stratum basale is a continuous layer of cells...

. Nourishment is provided to these layers via diffusion

Diffusion

Molecular diffusion, often called simply diffusion, is the thermal motion of all particles at temperatures above absolute zero. The rate of this movement is a function of temperature, viscosity of the fluid and the size of the particles...

 from the dermis, since the epidermis is without direct blood supply. The epidermis contains four cell types: keratinocyte

Keratinocyte

Keratinocytes are the predominant cell type in the epidermis, the outermost layer of the human skin, constituting 95% of the cells found there. Those keratinocytes found in the basal layer of the skin are sometimes referred to as "basal cells" or "basal keratinocytes"...

s, melanocyte

Melanocyte

-External links: - "Eye: fovea, RPE" - "Integument: pigmented skin"...

s, Langerhans cell

Langerhans cell

Langerhans cells are dendritic cells of the skin and mucosa, and contain large granules called Birbeck granules. They are present in all layers of the epidermis, but are most prominant in the stratum spinosum. They also occur in the papillary dermis, particularly around blood vessels, as well as...

s, and Merkel cell

Merkel cell

Merkel cells or Merkel-Ranvier cells are oval receptor cells found in the skin of vertebrates that have synaptic contacts with somatosensory afferents. They are associated with the sense of light touch discrimination of shapes and textures. They can turn malignant and form the skin tumor known as...

s. Of these, keratinocytes are the major component, constituting roughly 95 percent of the epidermis. This stratified squamous epithelium is maintained by cell division within the stratum basale, in which differentiating cells slowly displace outwards through the stratum spinosum to the stratum corneum, where cells are continually shed from the surface. In normal skin, the rate of production equals the rate of loss; it takes about two weeks for a cell to migrate from the basal cell layer to the top of the granular cell layer, and an additional two weeks to cross the stratum corneum.

The dermis is the layer of skin between the epidermis and subcutaneous tissue, and comprises two sections, the papillary dermis and the reticular dermis

Reticular dermis

The reticular dermis is the lower layer of the dermis, found under the papillary dermis, composed of dense irregular connective tissue featuring densely packed collagen fibers. It is the primary location of dermal elastic fibers....

. The superficial papillary dermis interdigitates with the overlying rete ridges of the epidermis, between which the two layers interact through the basement membrane zone. Structural components of the dermis are collagen

Collagen

Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content...

, elastic fibers, and extrafibrillar matrix (previously called ground substance

Ground substance

Ground substance is a term for the non-cellular components of extracellular matrix which contain the fibers.It is usually not visible on slides, because it is removed during the preparation process....

). Within these components are the pilosebaceous units, arrector pili muscles, and the eccrine and apocrine glands. The dermis contains two vascular networks that run parallel to the skin surface—one superficial and one deep plexus—which are connected by vertical communicating vessels. The function of blood vessels within the dermis is fourfold: to supply nutrition, to regulate temperature, to modulate inflammation, and to participate in wound healing.

The subcutaneous tissue is a layer of fat between the dermis and underlying fascia

Fascia

A fascia is a layer of fibrous tissue that permeates the human body. A fascia is a connective tissue that surrounds muscles, groups of muscles, blood vessels, and nerves, binding those structures together in much the same manner as plastic wrap can be used to hold the contents of sandwiches...

. This tissue may be further divided into two components, the actual fatty layer, or panniculus adiposus

Panniculus adiposus

The panniculus adiposus is the fatty layer of the subcutaneous tissues, superficial to a deeper vestigial layer of muscle, the panniculus carnosus.It includes structures that are considered fascia by some sources but not by others....

, and a deeper vestigial layer of muscle, the panniculus carnosus

Panniculus carnosus

The panniculus carnosus is a part of the subcutaneous tissues in the study of animal anatomy. It is a layer of striated muscle deep to the panniculus adiposus. In humans the platysma muscle of the neck, palmaris brevis in the hand, and the dartos muscle in the scrotum are described as a discrete...

. The main cellular component of this tissue is the adipocyte

Adipocyte

However, in some reports and textbooks, the number of fat cell increased in childhood and adolescence. The total number is constant in both obese and lean adult...

, or fat cell. The structure of this tissue is composed of septal (i.e. linear strands) and lobular

Lobe (anatomy)

In anatomy, a lobe is a clear anatomical division or extension that can be determined without the use of a microscope This is in contrast to a lobule, which is a clear division only visible histologically....

 compartments, which differ in microscopic appearance. Functionally, the subcutaneous fat insulates the body, absorbs trauma, and serves as a reserve energy source.

Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia

Melanonychia

Melanonychia is a black or brown pigmentation of the normal nail plate, and may be present as a normal finding on many digits in black patients, as a result of trauma, systemic disease, or medications, or as a postinflammatory event from such localized events as lichen planus or fixed drug...

 and racquet nails

Racquet nails

In Racquet nails , the end of the thumb is widened and flattened, the nail plate is flattened as well, and the distal phalanx is abnormally short. Racquet nails occur on one or both thumbs and are apparently inherited as an autosomal-dominant trait...

). While only a small number of skin diseases account for most visits to the physician

Physician

A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

, thousands of skin conditions have been described. Classification of these conditions often presents many nosological challenges, since underlying etiologies and pathogenetics are often not known. Therefore, most current textbooks present a classification based on location (for example, conditions of the mucous membrane), morphology (chronic blistering conditions), etiology (skin conditions resulting from physical factors), and so on. Clinically, the diagnosis of any particular skin condition is made by gathering pertinent information regarding the presenting skin lesion(s), including the location (such as arms, head, legs), symptoms (pruritus, pain), duration (acute or chronic), arrangement (solitary, generalized, annular, linear), morphology (macules, papule

Papule

A papule is a circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to 1 cm.With regard to the quote "...varying in size from a pinhead to 1cm," depending on which text is referenced, some authors state the cutoff between a papule and a plaque as 0.5cm,...

s, vesicles), and color (red, blue, brown, black, white, yellow). The diagnosis of a many conditions often also requires a skin biopsy

Skin biopsy

Skin biopsy is a biopsy technique in which a skin lesion is removed and sent to the pathologist to render a microscopic diagnosis. It is usually done under local anesthetic in a physician's office, and results are often available in 4 to 10 days. It is commonly performed by dermatologists. Skin...

 which yields histologic information that can be correlated with the clinical presentation and any laboratory data.

Acneiform eruptions

Acneiform eruption

Acneiform eruption

Acneiform eruption refers to a group of dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis. Restated, acneiform eruptions are follicular eruptions characterized by papules and pustules resembling acne....

s are caused by changes in the pilosebaceous unit

Pilosebaceous unit

The Pilosebaceous unit is an epidermal invagination found on most surfaces of the human body....

.

• Acne aestivalis
  Acne aestivalis
  Acne aestivalis is a special form of polymorphous light eruption. It is a monomorphous eruption consisting of multiple, uniform, red, papular lesions, reported to occur after sun exposure....
  
   (Mallorca acne)Any given cutaneous condition is only included once within this list.Parentheticals are used to indicate other names by which a condition is known. If there are multiple alternative names for a condition, they are separated by commas within the parenthetical.Citations for any given condition name and/or alternative name(s) may be found within the condition's respective article.
• Acne conglobata
  Acne conglobata
  Acne conglobata is a highly inflammatory disease presenting with comedones, nodules, abscesses, and draining sinus tracts.This condition generally begins between the ages of 18 and 30. It usually persists for a very long time, and often until the patient is around 40 years old...
  
  
• Acne cosmetica
  Acne cosmetica
  Acne cosmetica is a term referring to acne caused by or made worse by cosmetics. The mechanism was presumably a chemically induced plugging of the pilosebaceous orifice...
  
   (Cosmetic acne)
• Acne fulminans
  Acne fulminans
  Acne fulminans is a severe form of the skin disease, acne, which can occur after unsuccessful treatment for another form of acne, acne conglobata. The condition is thought to be an immunologically induced disease in which elevated level of testosterone causes a rise in sebum and Propionibacterium...
  
   (Acute febrile ulcerative acne)
• Acne keloidalis nuchae
  Acne keloidalis nuchae
  Acne keloidalis nuchae is a destructive scarring folliculitis that occurs almost exclusively on the occipital scalp of people of African descent, primarily men...
  
   (Acne keloidalis, Dermatitis papillaris capillitii, Folliculitis keloidalis, Folliculitis keloidis nuchae, Nuchal keloid acne)
• Acne mechanica
  Acne mechanica
  Acne mechanica is an acneiform eruption that has been observed after repetitive physical trauma to the skin such as rubbing, occurring from clothing or sports equipment ....
  
  
• Acne medicamentosa
  Acne medicamentosa
  Acne medicamentosa is acne that is caused or aggravated by medication. Because acne is generally a disorder of the pilosebaceous units caused by hormones, the medications that trigger acne medicamentosa most frequently are hormone analogues...
  
  
• Acne miliaris necrotica
  Acne miliaris necrotica
  Acne miliaris necrotica consists of follicular vesicopustules, sometimes occurring as solitary lesions that are usually very itchy....
  
   (Acne varioliformis)
• Acne vulgaris
  Acne vulgaris
  Acne vulgaris is a common human skin disease, characterized by areas of skin with seborrhea , comedones , papules , pustules , Nodules and possibly scarring...
  
   
  
• Acne with facial edema
  Acne with facial edema
  Acne with facial edema occurs uncommonly, and is associated with a peculiar inflammatory edema of the mid-third of the face....
  
   (Solid facial edema)This list uses American English; therefore, the symbols æ
  Æ
  Æ is a grapheme formed from the letters a and e. Originally a ligature representing a Latin diphthong, it has been promoted to the full status of a letter in the alphabets of some languages, including Danish, Faroese, Norwegian and Icelandic...
  
   and œ
  Œ
  Œ œŒ is a Latin alphabet grapheme, a ligature of o and e. In medieval and early modern Latin, it was used to represent the Greek diphthong οι, a usage which continues in English and French...
  
  , which are common to British English, are not used, but, rather, simplified to a single e
  E
  E is the fifth letter and a vowel in the basic modern Latin alphabet. It is the most commonly used letter in the Czech, Danish, Dutch, English, French, German, Hungarian, Latin, Norwegian, Spanish, and Swedish languages.-History:...
  
  . For example, the spelling of nevus
  Nevus
  Nevus is the medical term for sharply-circumscribed and chronic lesions of the skin. These lesions are commonly named birthmarks and moles. Nevi are benign by definition...
  
   is favored over nævus, edema
  Edema
  Edema or oedema ; both words from the Greek , oídēma "swelling"), formerly known as dropsy or hydropsy, is an abnormal accumulation of fluid beneath the skin or in one or more cavities of the body that produces swelling...
  
   over œdema, and so forth. For more information, see American and British English differences
  American and British English differences
  This is one of a series of articles about the differences between British English and American English, which, for the purposes of these articles, are defined as follows:...
  
  .
• Blepharophyma
  Blepharophyma
  Blepharophyma refers to chronic swelling of eyelids, mainly due to sebaceous gland hyperplasia....
  
  
• Erythrotelangiectatic rosacea
  Erythrotelangiectatic rosacea
  Erythrotelangiectatic rosacea is characterized by prominent history of prolonged flushing reaction to various stimuli, such as emotional stress, hot drinks, alcohol, spicy foods, exercise, cold or hot weather, or hot baths and showers....
  
   (Erythematotelangiectatic rosacea, Vascular rosacea)
• Excoriated acne
  Excoriated acne
  Excoriated acne is a mild acne accompanied by extensive excoriations....
  
   (Acne excoriée des jeunes filles, Picker's acne)Non-English names are included within this list when those terms are found in English medical literature
  Medical literature
  Medical literature refers to articles in journals and texts in books devoted to the field of medicine.Contemporary and historic views regarding diagnosis, prognosis and treatment of medical conditions have been documented for thousands of years. The Edwin Smith papyrus is the first known medical...
  
  . Inclusion of acne excoriée des jeunes filles (French
  French language
  French is a Romance language spoken as a first language in France, the Romandy region in Switzerland, Wallonia and Brussels in Belgium, Monaco, the regions of Quebec and Acadia in Canada, and by various communities elsewhere. Second-language speakers of French are distributed throughout many parts...
  
  ), frambösie (German
  German language
  German is a West Germanic language, related to and classified alongside English and Dutch. With an estimated 90 – 98 million native speakers, German is one of the world's major languages and is the most widely-spoken first language in the European Union....
  
  ), and parangi (Malay
  Malay language
  Malay is a major language of the Austronesian family. It is the official language of Malaysia , Indonesia , Brunei and Singapore...
  
  ) represent examples of this convention
  Convention (norm)
  A convention is a set of agreed, stipulated or generally accepted standards, norms, social norms or criteria, often taking the form of a custom....
  
  .
• Glandular rosacea
  Glandular rosacea
  In Glandular rosacea, men with thick sebaceous skin predominate, a disease in which the papules are edematous, the pustules often 0.5 to 1.0cm in size, with nodulocystic lesions often present....
  
  
• Gnathophyma
• Gram-negative rosacea
  Gram-negative rosacea
  Gram-negative rosacea is a cutaneous condition that clinically looks like stage II or III rosacea....
  
  
• Granulomatous facial dermatitis
  Granulomatous facial dermatitis
  Granulomatous facial dermatitis is found in patients with persistent facial erythema involving one or more convex surfaces of the face, with lesions that show granulomatous reaction histologically....
  
  
• Granulomatous perioral dermatitis
  Granulomatous perioral dermatitis
  Granulomatous perioral dermatitis is a cutaneous condition found in otherwise healthy prepubertal children, in which there is a profusion of grouped papules on the perioral, periocular, and perinasal areas.-See also:* List of cutaneous conditions...
  
  
• Halogen acne
  Halogen acne
  Halogen acne is caused by iodides and bromides that induce an acneiform eruption similar to that observed with steroids....
  
  
• Hidradenitis suppurativa
  Hidradenitis suppurativa
  Hidradenitis suppurativa is a skin disease that most commonly affects areas bearing apocrine sweat glands or sebaceous glands, such as the underarms, breasts, inner thighs, groin and buttocks.-Overview:...
  
   (Acne inversa, Pyoderma fistulans significa, Verneuil's disease)
• Idiopathic facial aseptic granuloma
  Idiopathic facial aseptic granuloma
  Idiopathic facial aseptic granuloma is a cutaneous condition characterized by a chronic, painless, solitary nodule, reminiscent of an acne nodule, appearing on the cheeks of young children....
  
  
• Infantile acne
• Lupoid rosacea
  Lupoid rosacea
  Lupoid rosacea is characterized by the development of epithelioid granulomas in a diffuse pattern....
  
   (Granulomatous rosacea, Micropapular tuberculid, Rosacea-like tuberculid of Lewandowsky)
• Lupus miliaris disseminatus faciei
  Lupus miliaris disseminatus faciei
  Lupus miliaris disseminatus faciei is a disease with a similar appearance to acne vulgaris....
  
  
• Metophyma
  Metophyma
  Metophyma refers to cushion-like swellings on the forehead above the saddle of the nose....
  
  
• Neonatal acne
  Neonatal acne
  Neonatal acne is an acneiform eruption that occurs in newborns or infants, and is often seen on the nose and adjacent portions of the cheeks.....
  
   (Acne infantum, Acne neonatorum, Neonatal cephalic pustulosis)
• Occupational acne
  Occupational acne
  Occupational acne is caused by several different groups of industrial compounds, including coal tar derivatives, insoluble cutting oils, and chlorinated hydrocarbons ....
  
  
• Oil acne
• Ocular rosacea
  Ocular rosacea
  Ocular rosacea is a manifestation of rosacea that affects the eyes and eyelids. Symptoms generally consist of redness, irritation or burning of the eyes. Patients may also feel that there is something, such as an eyelash, in the eye...
  
   (Ophthalmic rosacea, Ophthalmorosacea)
• Otophyma
• Periorificial dermatitis
  Periorificial dermatitis
  Periorificial dermatitis is a cutaneous condition characterized by a combination of perioral dermatitis and periocular dermatitis....
  
  
• Persistent edema of rosacea
  Persistent edema of rosacea
  Persistent edema of rosacea is a hard, nonpitting edema found on the areas involved, those mainly being the forehard, glabella, upper eyelids, nose, and/or cheeks.Persistent edema of rosacea is an uncommon cutaneous condition characterized by a hard, nonpitting edema restricted to...
  
   (Chronic upper facial erythematous edema, Morbihan's disease, Rosaceous lymphedema)
• Phymatous rosacea
• Pomade acne
  Pomade acne
  Pomade acne occurs when some of the pomade that is applied to the scalp is also applied to the forehead and is responsible for the development of multiple, closely packed comedones close to the hairline....
  
  
• Papulopustular rosacea
  Papulopustular rosacea
  Papulopustular rosacea manifests a strikingly red central face accompanied by erythematous papules often surrounded by a pinpoint pustule....
  
   (Inflammatory rosacea)
• Perifolliculitis capitis abscedens et suffodiens
  Perifolliculitis capitis abscedens et suffodiens
  Perifolliculitis capitis abscedens et suffodiens is an inflammatory condition of the scalp that can lead to scarring alopecia, which begins with deep inflammatory nodules, primarily over occiput, that progresses to coalescing regions of boggy...
  
   (Dissecting cellulitis of the scalp, Dissecting folliculitis, Perifolliculitis capitis abscedens et suffodiens of Hoffman)
• Perioral dermatitis
  Perioral dermatitis
  Perioral dermatitis, a condition related to acne vulgaris, consists of red papules that may appear microvesicular that typically affect the nasolabial folds , perioral area or perioccular area . It usually affects women between the ages of 20 and 45...
  
  
• Periorbital dermatitis
  Periorbital dermatitis
  Periorbital dermatitis is a skin condition, a variant of perioral dermatitis, occurring on the lower eyelids and skin adjacent to the upper and lower eyelids.- See also :* Granulomatous perioral dermatitis...
  
   (Periocular dermatitis)
• Pyoderma faciale
  Pyoderma faciale
  Pyoderma faciale is a conglobate, nodular disease springing up abruptly on the face....
  
   (Rosacea fulminans)
• Rhinophyma
  Rhinophyma
  Rhinophyma is a descriptive term for a large, bulbous, ruddy appearance of the nose caused by granulomatous infiltration, commonly due to untreated rosacea.- Causes :...
  
  
• Rosacea
  Rosacea
  Rosacea is a chronic condition characterized by facial erythema . Pimples are sometimes included as part of the definition. Unless it affects the eyes, it is typically a harmless cosmetic condition...
  
   (Acne rosacea)
• Rosacea conglobata
  Rosacea conglobata
  Rosacea conglobata is a severe rosacea that shows a reaction which mimics acne conglobata with hemorrhagic nodular abscesses and indurated plaques....
  
  
• Synovitis–acne–pustulosis–hyperostosis–osteomyelitis syndrome (SAPHO syndrome)Abbreviations for condition names commonly described in medical literature with an acronym or initialism
  Acronym and initialism
  Acronyms and initialisms are abbreviations formed from the initial components in a phrase or a word. These components may be individual letters or parts of words . There is no universal agreement on the precise definition of the various terms , nor on written usage...
  
   are included within this list.
• Steroid rosacea
  Steroid rosacea
  Steroid induced rosacea is an iatrogenic condition from the use of either systemic steroid or topical steroids. It is nearly identical to steroid induced acne from the standpoint of etiology.- Etiology :...
  
  
• Tar acne
• Tropical acne
  Tropical acne
  Tropical acne is unusually severe acne occurring in the tropics during seasons when the weather is hot and humid....
  
  

Autoinflammatory syndromes

Autoinflammatory syndromes are a group of inherited disorders characterized by bouts of inflammatory

Inflammation

Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...

 skin lesions and periodic fevers

Fevers

Fevers are a five-piece band formed in 2010 in Ottawa, Ontario. The band consists of Colin MacDougall , Jim Hopkins , Martin Charbonneau , Sarah Bradley and Mike Stauffer . Theirs is a fresh take on a classic genre, combining indie rock and electronic music...

.

• Blau syndrome
  Blau syndrome
  Blau syndrome is characterized by familial granulomatous arthritis, iritis, and skin granulomas, comprising an autosomal dominantly inherited syndrome that overlaps both sarcoidosis and granuloma annulare....
  
   
• Chronic infantile neurologic cutaneous and articular syndrome
• Familial cold urticaria
  Familial cold urticaria
  Familial cold urticaria is an autosomal dominant condition characterized by rash, conjunctivitis, fever/chills and arthralgias elicited by exposure to cold - sometimes temperatures below 22°C .It has been mapped to CIAS1 and is a slightly milder member of the disease family including Muckle–Wells...
  
   (Familial cold autoinflammatory syndrome)
• Familial Mediterranean fever
  Familial Mediterranean fever
  Familial Mediterranean fever is a hereditary inflammatory disorder. FMF is an autoinflammatory disease caused by mutations in MEFV, a gene which encodes a 781–amino acid protein denoted pyrin....
  
  
• Hyper-IgD syndromeWithin this list, the term immunoglobulin is abbreviated to Ig when used as a prefix to a specific antibody isotype (i.e. IgA
  IGA
  Iga or IGA may stand for:-Given name:* a female given name of Polish origin. The name originates from the female given name Jadwiga and stands for gia,or gina in the USA....
  
  , IgD
  IGD
  IGD can refer to:*Internet Gateway Device as defined in UPnP.*İGD, İlerici Gençler Derneği, Progressive Young Association of Turkey*Immunoglobulin D, an antibody protein involved in the maturation of B cells....
  
  , IgE
  IGE
  IGE was one of the largest services company buying and selling virtual currencies and accounts for MMORPG. During its peak time, it had offices in Los Angeles, China , and headquarters & customer service centre in Hong Kong. IGE was one of the main monopoly in virtual economy services, also known...
  
  , IgG, and IgM
  IGM
  IGM as an acronym or abbreviation can refer to:* Immunoglobulin M , the primary antibody against A and B antigens on red blood cells* International Grandmaster, a chess ranking* intergalactic medium* Intragroup medium - see: Intracluster medium...
  
  ).
• Majeed syndrome
  Majeed syndrome
  Majeed syndrome is an inherited skin disorder characterized by chronic multifocal osteomyelitis, congenital dyserythropoietic anemia and a neutrophilic dermatosis....
  
  
• Muckle–Wells syndrome
• TNF receptor associated periodic syndrome
  TNF receptor associated periodic syndrome
  TNF receptor associated periodic syndrome is a periodic fever syndrome associated with mutations in a receptor for the molecule tumor necrosis factor that is inheritable in an autosomal dominant manner...
  
   (Familial Hibernian fever, TRAPS, Tumor necrosis factor receptor associated periodic syndrome)

Chronic blistering

Chronic blistering cutaneous conditions have a prolonged course and present with vesicles and bullae.

• Adult linear IgA disease
  Adult linear IgA disease
  Adult linear IgA disease is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance.- See also :...
  
  
• Bullous pemphigoid
  Bullous pemphigoid
  Bullous pemphigoid, also referred to as BP, is an acute or chronic autoimmune skin disease, involving the formation of blisters, more appropriately known as bullae, at the space between the skin layers epidermis and dermis.-Signs and symptoms:...
  
  
• Childhood linear IgA disease
  Childhood linear IgA disease
  Childhood linear IgA disease is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13. -See also:* Adult linear IgA disease...
  
   (Chronic bullous disease of childhood)
• Cicatricial pemphigoid
  Cicatricial pemphigoid
  Cicatricial pemphigoid is a rare chronic autoimmune subepithelial blistering disease characterized by erosive skin lesions of the mucous membranes and skin that results in scarring of at least some sites of involvement.Cicatricial pemphigoid has been referred...
  
   (Benign mucosal pemphigoid, Benign mucous membrane pemphigoid, Ocular pemphigus, Scarring pemphigoid)
• Dermatitis herpetiformis
  Dermatitis herpetiformis
  Dermatitis herpetiformis , or Duhring's disease,Freedberg, et al. . Fitzpatrick's Dermatology in General Medicine. . McGraw-Hill. ISBN 0-07-138076-0. is a chronic blistering skin condition, characterised by blisters filled with a watery fluid...
  
   (Duhring disease)
• Endemic pemphigus
  Endemic pemphigus
  Endemic pemphigus, also known as endemic pemphigus foliaceus and fogo selvagem , is a disease that is clinically, histologically, and immunopathologically the same as sporadic pemphigus foliaceus in any individual patient, but that is endemic in the rural areas of Brazil, especially along inland...
  
   (Endemic pemphigus foliaceus, Fogo selvagem)
• Epidermolysis bullosa acquisita
  Epidermolysis bullosa acquisita
  Epidermolysis bullosa acquisita is a chronic subepidermal blistering disease associated with autoimmunity to type VII collagen within anchoring fibril structures that are located at the dermal-epidermal junction....
  
  
• Grover's disease
  Grover's disease
  Grover's disease is a polymorphic, pruritic, papulovesicular dermatosis characterized histologically by acantholysis....
  
   (Benign papular acantholytic dermatosis, Persistent acantholytic dermatosis, Transient acantholytic dermatosis)
  
• IgA pemphigus
  IgA pemphigus
  IgA pemphigus is a subtype of pemphigus with two distinct forms, subcorneal pustular dermatosis and intraepidermal neutrophilic IgA dermatosis....
  
  
• Intraepidermal neutrophilic IgA dermatosis
  Intraepidermal neutrophilic IgA dermatosis
  Intraepidermal neutrophilic IgA dermatosis is characterized histologically by intraepidermal bullae with neutrophils, some eosinophils, and acantholysis....
  
  
• Localized cicatricial pemphigoid
  Localized cicatricial pemphigoid
  Localized cicatricial pemphigoid is a cutaneous condition, a cutaneous cicatricial pemphigoid involving the head and the neck without mucosal involvement....
  
   (Brunsting–Perry cicatricial pemphigoid)
• Paraneoplastic pemphigus
  Paraneoplastic pemphigus
  Paraneoplastic pemphigus is an autoimmune disorder that is almost invariably linked to an underlying lymphoproliferative disorder.-External links:*Wikipedia Pemphigus Page with PNP Information*...
  
  
• Pemphigus erythematosus
  Pemphigus erythematosus
  Pemphigus erythematosus is simply a localized form of pemphigus foliaceus....
  
   (Senear–Usher syndrome)
• Pemphigus foliaceus
  Pemphigus foliaceus
  Pemphigus foliaceus is an autoimmune blistering disease of the skin and mucous membranes with characteristic lesions that are scaly, crusted erosions, often on an erythematous base...
  
  
• Pemphigus herpetiformis
  Pemphigus herpetiformis
  Pemphigus herpetiformis is a cutaneous condition, a clinical variant of pemphigus that combines the clinical features of dermatitis herpetiformis with the immunopathologic features of pemphigus....
  
   (Acantholytic herpetiform dermatitis, Herpetiform pemphigus, Mixed bullous disease, Pemphigus controlled by sulfapyridine)
• Pemphigoid nodularis
  Pemphigoid nodularis
  Pemphigoid nodularis is a cutaneous condition that is a variant of bullous pemphigoid that has skin lesions mimicking prurigo nodularis.The antibody involved is IgG....
  
  
• Pemphigus vegetans
  Pemphigus vegetans
  Pemphigus vegetans is a localized form of pemphigus vulgaris.in which there is a localized vegetating papillomatous response. The eroded areas do not heal like usual but form papillomatous growth and vegetation....
  
  
• Pemphigus vegetans of Hallopeau
  Pemphigus vegetans of Hallopeau
  Pemphigus vegetans of Hallopeau is a disease of localized pemphigus vulgaris.It is named for François Henri Hallopeau....
  
  
• Pemphigus vegetans of Neumann
  Pemphigus vegetans of Neumann
  Pemphigus vegetans of Neumann is a localized disease of pemphigus vulgaris slightly more extensive than pemphigus vegetans of Hallopeau....
  
  
• Pemphigus vulgaris
  Pemphigus vulgaris
  Pemphigus vulgaris is a chronic blistering skin disease with skin lesions that are rarely pruritic, but which are often painful.-Pathophysiology:...
  
  
• Vesicular pemphigoid
  Vesicular pemphigoid
  Vesicular pemphigoid is a cutaneous condition, a clinical variant of bullous pemphigoid, characterized by a dermatitis herpetiformis-like presentation with grouped small tense blisters....
  
  
• Vulvar childhood pemphigoid
  Vulvar childhood pemphigoid
  Vulvar childhood pemphigoid is a cutaneous condition, a childhood form of bullous pemphigoid, peculiar variant with involvement of the genital area and perineum....
  
  

Conditions of the mucous membranes

Conditions of the mucous membranes involve the moist linings of the eyes, nose, mouth, genitals, and anus.

• Acatalasia
  Acatalasia
  Acatalasia is an autosomal recessive peroxisomal disorder caused by a complete lack of catalase.-Presentation:...
  
   (Acatalasemia, Takahara's disease)
• Acquired dyskeratotic leukoplakia
  Acquired dyskeratotic leukoplakia
  Acquired dyskeratotic leukoplakia is a condition characterized by distinctive white plaques on the palate, gingivae, and lips.- See also :* List of cutaneous conditions* Proliferative verrucous leukoplakia* Mucous membrane...
  
  
• Actinic cheilitis
  Actinic cheilitis
  Actinic cheilitis is a form of cheilitis which is the counterpart of actinic keratosis of the skin and can develop into squamous cell carcinoma. In actinic cheilitis, there is thickening whitish discoloration of the lip at the border of the lip and skin...
  
   (Actinic cheilosis)
• Acute necrotizing ulcerative gingivitis (Acute membranous gingivitis, Acute necrotizing ulcerative gingivostomatitis, Fusospirillary gingivitis, Fusospirillosis, Fusospirochetal gingivitis, Necrotizing gingivitis, Phagedenic gingivitis, Trench mouth, Ulcerative gingivitis, Vincent gingivitis, Vincent infection, Vincent stomatitis, Vincent's disease)
• Allergic contact cheilitis
  Allergic contact cheilitis
  Allergic contact cheilitis is a conditions of the lips characterized by a dryness, fissuring, edema, and crusting....
  
   
  
• Angina bullosa haemorrhagica
  Angina bullosa haemorrhagica
  Angina bullosa haemorrhagica is a condition of the mucous membranes characterized by the sudden appearance of one or more blood blisters within the oral cavity....
  
  
• Angular cheilitis
  Angular cheilitis
  Angular cheilitis is an inflammatory lesion at the labial commissure, or corner of the mouth, and often occurs bilaterally. The condition manifests as deep cracks or splits...
  
   (Perlèche)
• Behçet's disease
  Behçet's disease
  Behçet's disease is a rare immune-mediated systemic vasculitis that often presents with mucous membrane ulceration and ocular involvements...
  
   (Behçet's syndrome, Oculo-oral-genital syndrome)
• Black hairy tongue (Hairy tongue, Lingua villosa nigra)
• Caviar tongue
  Caviar tongue
  Caviar tongue is a condition characterized by purplish venous ectasias commonly found on the undersurface of the tongue after the age of fifty.- See also :* Cutaneous sinus of dental origin* List of cutaneous conditions* Median rhomboid glossitis...
  
  
• Cheilitis exfoliativa
  Cheilitis exfoliativa
  Cheilitis exfoliativa is an inflammatory condition of the lips, in which they may be covered with crusts....
  
  
• Cheilitis glandularis
  Cheilitis glandularis
  Cheilitis glandularis is a conditions characterized by swelling and eversion of the lower lip. Cheilitis glandularis is an acquired disorder, of unknown aetiology, characterized by swelling, ulceration, crusting, mucous gland hyperplasia, abscesses, and sinus tracts....
  
  
• Cheilitis granulomatosa
  Cheilitis granulomatosa
  Cheilitis granulomatosa is a condition characterized by a sudden onset and progressive course terminating in chronic enlargement of the lips....
  
   (Granulomatous cheilitis, Orofacial granulomatosis)
• Cutaneous sinus of dental origin
  Cutaneous sinus of dental origin
  Cutaneous sinus of dental origin is a condition in which a chronic periapical infection about a tooth produces a burrowing cordlike sinus tract that eventually appears beneath the surface of the gum, palate, or periorificial skin.- See also :* Caviar tongue* List of cutaneous conditions* Median...
  
   (Dental sinus)
• Cyclic neutropenia
  Cyclic neutropenia
  Cyclic neutropenia is a form of neutropenia that tends to occur every three weeks and lasting three to six days at a time due to changing rates of cell production by the bone marrow....
  
  
• Desquamative gingivitis
  Desquamative gingivitis
  Desquamative gingivitis is a cutaneous condition characterized by diffuse gingival erythema with varying degrees of mucosal sloughing and erosion.A band of red atrophic or eroded mucosa affecting the attached gingiva is known as dequamative gingivitis...
  
  
• Drug-induced ulcer of the lip
  Drug-induced ulcer of the lip
  A drug-induced ulcer of the lip is a condition characterized by painful or tender, well-defined ulcerations of the lip without induration....
  
  
• Epidermization of the lip
  Epidermization of the lip
  Epidermization of the lip is a condition characterized by relatively smooth leukokeratosis of the lower lip....
  
  
• Epulis
  Epulis
  - See also :* Epulis fissuratum* Leukoplakia* List of cutaneous conditions* Mucous membrane* Congenital epulis...
  
  
• Epulis fissuratum
  Epulis fissuratum
  Epulis fissuratum is an oral pathologic condition that appears in the mouth as an overgrowth of fibrous connective tissue. Also referred to less commonly as inflammatory fibrous hyperplasia, denture epulis, and denture induced fibrous hyperplasia, it is associated with the edges of a denture that...
  
   (Granuloma fissuratum)
• Eruptive lingual papillitis
  Eruptive lingual papillitis
  Eruptive lingual papillitis is a condition characterized by an acute, self-limiting inflammatory stomatitis.- See also :* List of cutaneous conditions* Median rhomboid glossitis* Smooth tongue* Skin lesion...
  
  
• Erythroplakia
  Erythroplakia
  Erythroplakia is a flat red patch or lesion in the mouth that cannot be attributed to any other pathology.A similar term is "erythroplasia", which has a papular appearance.- Diagnosis and associated conditions :...
  
   (Erythroplasia)
• Fissured tongue
  Fissured tongue
  Fissured tongue is a benign condition characterized by deep grooves in the dorsum of the tongue...
  
   (Furrowed tongue, Lingua plicata, Plicated tongue, Scrotal tongue)
• Geographic tongue
  Geographic tongue
  Geographic tongue, an inflammatory condition of the tongue affecting approximately 2% of the population, is characterized by discolored regions of taste buds or sometimes even cracks in the tongue...
  
   (Benign migratory glossitis, Benign migratory stomatitis, Glossitis areata exfoliativa, Glossitis areata migrans, Lingua geographica, Stomatitis areata migrans, Transitory benign plaques of the tongue)
• Gingival fibroma
  Gingival fibroma
  Gingival fibroma is a cutaneous condition that may be observed with another condition, tuberous sclerosis....
  
  
• Gingival hypertrophy
  Gingival hypertrophy
  Gingival hypertrophy is a condition that may be seen in the setting of a vitamin C deficiency....
  
  
• Hairy leukoplakia
  Hairy leukoplakia
  Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance.-Causes:...
  
   (Oral hairy leukoplakia)
• Intraoral dental sinus
  Intraoral dental sinus
  Intraoral dental sinus is a cutaneous condition and is characterized by a soft, non-tender, erythematous papule that develops on the alveolar process....
  
  
• Leukoplakia
  Leukoplakia
  Leukoplakia is a clinical term used to describe patches of keratosis. It is visible as adherent white patches on the mucous membranes of the oral cavity, including the tongue, but also other areas of the gastro-intestinal tract, urinary tract and the genitals. The clinical appearance is highly...
  
  
• Leukoplakia with tylosis and esophageal carcinoma
  Leukoplakia with tylosis and esophageal carcinoma
  Leukoplakia with tylosis and esophageal carcinoma is a rare condition characterized by leukoplakia associated with esophageal carcinoma....
  
  
• Major aphthous ulcer
  Major aphthous ulcer
  Major aphthous ulcer is a condition of the oral mucosa characterized by a painful, shotlike nodule on the inner lip, buccal mucosa, or tongue....
  
   (Periadenitis mucosa necrotica recurrens)
• Median rhomboid glossitis
  Median rhomboid glossitis
  Median rhomboid glossitis is a condition characterized by a shiny oval or diamond-shaped elevation, invariably situated on the dorsum of the tongue in the midline immediately in front of the circumvallate papillae....
  
   (Central papillary atrophy)
• Melanocytic oral lesion
  Melanocytic oral lesion
  Melanocytic oral lesions are an extremely uncommon condition characterized by pigmented lesions of the mucous membranes.- See also :* List of cutaneous conditions* Mucosal squamous cell carcinoma* Mucous membrane* Oral florid papillomatosis...
  
  
• Melkersson–Rosenthal syndrome
• Morsicatio buccarum
  Morsicatio buccarum
  Morsicatio buccarum is a cutaneous condition characterized by chronic irritation or injury to the buccal mucosa from repetitive chewing, biting or nibbling produces characteristic changes in the tissue....
  
   (Chronic cheek biting, Chronic cheek chewing)
• Mucosal lichen planus
• Mucosal squamous cell carcinoma
• Mucous cyst of the oral mucosa (Mucocele)
• Nagayama's spots
• Oral Crohn's disease
• Oral florid papillomatosis
  Oral florid papillomatosis
  Oral florid papillomatosis is a condition characterized by a white mass resembling a cauliflower covering the tongue and extending onto other portions of the mucous membranes. This is a type of verrucous carcinoma.- See also :* Mucous membrane...
  
  
• Oral melanosis
  Oral melanosis
  Oral melanosis is pigmentation of the oral cavity that tends to occur most frequently in black persons.- See also :* List of cutaneous conditions* Melanocytic oral lesion* Mucous membrane* White sponge nevus...
  
  
• Osseous choristoma of the tongue
  Osseous choristoma of the tongue
  Osseous choristoma of the tongue is a condition characterized by a nodule on the dorsum of the tongue containing mature lamellar bone without osteoblastic or osteoclastic activity.- See also :* Oral melanosis* Peripheral ameloblastoma* Mucous membrane...
  
  
• Peripheral ameloblastoma
• Plasma cell cheilitis
  Plasma cell cheilitis
  Plasma cell cheilitis is a condition characterized by a sharply outlined, infiltrated, dark red plaque with a lacquer-like glazing of the surface of the involved oral area....
  
   (Plasma cell gingivitis, Plasma cell orificial mucositi)
• Plasmoacanthoma
  Plasmoacanthoma
  Plasmoacanthoma is a condition of the oral mucosa characterized by a verrucous tumor with a plasma cell infiltrate....
  
  
• Proliferative verrucous leukoplakia
  Proliferative verrucous leukoplakia
  Proliferative verrucous leukoplakia is a slowly progressive condition characterized by thickened and enlarged sites of oral mucous membrane.- See also :* Acquired dyskeratotic leukoplakia* Oral florid papillomatosis* Mucous membrane...
  
  
• Pyogenic granuloma
  Pyogenic granuloma
  Pyogenic granuloma is a primarily oral disease which appears as an overgrowth of tissue due to irritation, physical trauma or hormonal factors...
  
   (Eruptive hemangioma, Granulation tissue-type hemangioma, Granuloma gravidarum, Lobular capillary hemangioma, Pregnancy tumor, Tumor of pregnancy)
• Pyostomatitis vegetans
  Pyostomatitis vegetans
  Pyostomatitis vegetans is an inflammatory stomatitis and most often seen in association with inflammatory bowel disease, namely ulcerative colitis and Crohn's disease.- See also :* Cheilitis* Cheilitis granulomatosa* Skin lesion...
  
  
• Recurrent aphthous stomatitis (Aphthosis, Canker sores, Recurrent oral aphthae)
• Recurrent intraoral herpes simplex infection
• Smooth tongue
  Smooth tongue
  Smooth tongue is a condition characterized by a smooth glossy tongue that is often tender/painful....
  
   (Atrophic glossitis, Bald tongue, Hunter glossitis, Moeller)
• Stomatitis nicotina
  Stomatitis nicotina
  Stomatitis nicotina is an oral pathological condition that appears in the hard palate of the mouth as a white lesion. It is not considered to be premalignant and results from tobacco smoking or long-term drinking of very hot beverages...
  
   (Nicotine stomatitis, Smoker's keratosis, Smoker's patches)
• Torus palatinus
  Torus palatinus
  Torus palatinus [palatinus torus in English] is a bony protrusion on the palate. Palatal tori are usually present on the midline of the hard palate...
  
  
• Trumpeter's wart
  Trumpeter's wart
  A trumpeter's wart is a cutaneous condition characterized by a firm, fibrous, hyperkeratotic nodule on the upper lip of a trumpet player....
  
  
• Vestibular papillomatosis
  Vestibular papillomatosis
  Vestibular papillomatosis is a cutaneous condition seen in women, characterized by pink, asymptomatic, fine projections. It is the female equivalent to hirsuties coronae glandis....
  
  
• White sponge nevus
  White sponge nevus
  White sponge nevus , also known as Cannon's disease, Hereditary leukokeratosis of mucosa and White sponge nevus of Cannon, is an autosomal dominant skin condition...
  
   (White sponge nevus of Cannon)

Conditions of the skin appendages

Conditions of the skin appendages are those affecting the glands of the skin, hair

Hair

Hair is a filamentous biomaterial, that grows from follicles found in the dermis. Found exclusively in mammals, hair is one of the defining characteristics of the mammalian class....

, nails

Nail (anatomy)

A nail is a horn-like envelope covering the dorsal aspect of the terminal phalanges of fingers and toes in humans, most non-human primates, and a few other mammals. Nails are similar to claws, which are found on numerous other animals....

, and arrector pili muscles.

• Acne necrotica
  Acne necrotica
  Acne necrotica present with a primary lesions that is a pruritic or painful erythematous follicular-based papule that develops central necrosis and crusting and heals with a varioliform scar....
  
  
• Acquired generalized hypertrichosis (Acquired hypertrichosis lanuginosa)
• Acquired perforating dermatosis
  Acquired perforating dermatosis
  Acquired perforating dermatosis is clinically and histopathologically similar to perforating folliculitis, also associated with chronic renal failure, with or without hemodialysis or peritoneal dialysis, and/or diabetes, but not identical to Kyrle disease.- References :...
  
   (Acquired perforating collagenosis)
• Acrokeratosis paraneoplastica of Bazex
  Acrokeratosis paraneoplastica of Bazex
  Acrokeratosis paraneoplastica of Bazex is a cutaneous condition characterized by psoriasiform changes of hands, feet, ears, and nose, with involvement of the nails and periungual tissues being characteristic and indistinguishable from psoriatic nails...
  
   (Acrokeratosis neoplastica, Bazex syndrome)
• Acroosteolysis
  Acroosteolysis
  Acroosteolysis is a cutaneous condition characterized by destructive changes in the distal phalangeal bone, and may be associated with minimal skin changes or with ischemic skin lesions that may result in digital necrosis....
  
  
• Acute paronychia
  Acute paronychia
  Acute paronychia may follow any break in the skin, characterized by an infection that starts in the paronychium at the side of the nail, with local redness, swelling, and pain....
  
   
  
• Alopecia areata
  Alopecia areata
  Alopecia areata is a medical condition in which hair is lost from some or all areas of the body, usually from the scalp. Because it causes bald spots on the scalp, especially in the first stages, it is sometimes called spot baldness. In 1–2% of cases, the condition can spread to the entire scalp ...
  
  
• Alopecia neoplastica
  Alopecia neoplastica
  Alopecia neoplastica may present as a scarring alopecia, appearing anywhere on the scalp, and it has been described with cutaneous metastasis from breast, gastric, lung, renal and pancreatic carcinomas....
  
  
• Anagen effluvium
  Anagen effluvium
  Anagen effluvium is the pathologic loss of anagen or growth-phase hairs. Classically, it is caused by radiation therapy to the head and systemic chemotherapy, especially with alkylating agents....
  
  
• Androgenic alopecia (Androgenetic alopecia)
• Anhidrosis
  Anhidrosis
  Anhidrosis means lack of sweating. It is also known by a number of other names including Adiaphoresis, Ischidrosis, Hypohidrosis, Oligidria, Oligohidrosis and Sweating deficiency.-Causes:...
  
   (Hypohidrosis)
• Anonychia
  Anonychia
  Anonychia is the absence of nails, a rare anomaly, which may be the result of a congenital ectodermal defect, ichthyosis, severe infection, severe allergic contact dermatitis, self-inflicted trauma, Raynaud phenomenon, lichen planus, epidermolysis bullosa, or severe exfoliative diseases.-References:...
  
  
• Apparent leukonychia
  Apparent leukonychia
  Apparent leukonychia is a cutaneous condition characterized by white discoloration of the nail that fades with pressure....
  
  
• Beau's lines
  Beau's lines
  Beau's lines are deep grooved lines that run from side to side on the fingernail. They may look like indentations or ridges in the nail plate. This condition of the nail was named by a French physician, Joseph Honoré Simon Beau , who first described it in 1846.Beau's lines are horizontal, going...
  
  
• Blue nails
  Blue nails
  Blue nails, or more formally azure lunula, are characterized by a blue discoloration of the lunulae, seen in argyria and cases of hepatolenticular degeneration , also having been reported in hemoglobin M disease and hereditary acrolabial telangiectases.In Wilson's disease the blue color involves...
  
  
• Bromidrosis (Apocrine bromhidrosis, Fetid sweat, Malodorous sweating, Osmidrosis)
• Bubble hair deformity
  Bubble hair deformity
  Bubble hair deformity is an abnormality of the hair shaft.It is characterized by rows of bubbles seen microscopically within localized areas of brittle hair....
  
  
• Central centrifugal cicatricial alopecia
  Central centrifugal cicatricial alopecia
  Central centrifugal cicatricial alopecia, hot comb alopecia, or follicular degeneration syndrome is a type of alopecia first noticed in African Americans in the 1950s and reported by LoPresti et al. in 1968 as a result of application of petrolatum followed by a stove-heated iron comb...
  
   (Follicular degeneration syndrome, Pseudopelade of the central scalp)
• Chevron nail
  Chevron nail
  Chevron nail is a rare transient fingernail ridge pattern seen in children, a ridge arising from the proximal nailfold and converging in a V-shaped pattern towards the midpoint distally....
  
   (Herringbone nail)
• Chromhidrosis
  Chromhidrosis
  Chromhidrosis Chromhidrosis Chromhidrosis (also referred to as "Colored sweat" is a rare condition characterized by the secretion of colored sweat. It is caused by the deposition of lipofuscin in the sweat glands. Cases of red, blue, green, yellow and black sweat have been reported. Usually...
  
   (Colored sweat)
• Chronic paronychia
  Chronic paronychia
  Chronic paronychia is a nail disorder prevalent in individuals whose hands or feet are subject to moist local environments and is often due to contact dermatitis....
  
  
• Cicatricial alopecia
  Cicatricial alopecia
  The term cicatricial alopecia refers to a diverse group of rare disorders that destroy the hair follicle, replace it with scar tissue, and cause permanent hair loss. A variety of distributions are possible. In some cases, hair loss is gradual, without symptoms, and is unnoticed for long periods...
  
  
• Clubbing (Drumstick fingers, Hippocratic fingers, Watch-glass nails)
• Congenital onychodysplasia of the index fingers
• Disseminate and recurrent infundibulofolliculitis
  Disseminate and recurrent infundibulofolliculitis
  Disseminate and recurrent infundibulofolliculitis presents with irregularly shaped papules pierced by hair, mildly pruritic at times, and is chronic with recurrent exacerbations....
  
  
• Erosive pustular dermatitis of the scalp
  Erosive pustular dermatitis of the scalp
  Erosive pustular dermatitis of the scalp presents with pustules, erosions, and crusts on the scalp of primarily older Caucasean females, and on biopsy, has a lymphoplasmacytic infiltrate with or without foreign body giant cells and pilosebaceous atrophy....
  
   (Erosive pustular dermatosis of the scalp)
• Erythromelanosis follicularis faciei et colli
  Erythromelanosis follicularis faciei et colli
  Erythromelanosis follicularis faciei et colli is an erythematous pigmentary disease involving the follicles, characterized by a reddish-brown, sharply demarcated, symmetrical discoloration involving the preauricular and maxillary regions....
  
  
• Folliculitis decalvans
  Folliculitis decalvans
  Folliculitis decalvans is an inflammatory alopecia that leads to bogginess or induration of involved parts of the scalp along with pustules, erosions, crusts, and scale. It begins at a central point and spreads outward, leaving scarring, sores, and hair loss in its wake...
  
  
• Folliculitis nares perforans
  Folliculitis nares perforans
  Folliculitis nares perforans is characterized by small pustules near the tip of the inside of the nose, lesions that become crusted, and when the crust is removed it is found that the bulbous end of the affected vibrissa is embedded in the inspissated material....
  
  
• Fox–Fordyce disease
• Frontal fibrosing alopecia
  Frontal fibrosing alopecia
  Frontal fibrosing alopecia is a term given to the frontotemporal hairline recession and eyebrow loss in postmenopausal women that is associated with perifollicular erythema, especially along the hairline....
  
  
• Generalized congenital hypertrichosis (Congenital hypertrichosis lanuginosa)
• Generalized hyperhidrosis
  Generalized hyperhidrosis
  Generalized hyperhidrosis is excessive sweating that may be induced by febrile diseases, vigorous exercise, or a hot, humid environment, such as a tropical milieu....
  
  
• Graham-Little syndrome
  Graham-Little syndrome
  Graham-Little syndrome is a cutaneous condition characterized by lichen planus-like skin lesions....
  
  
• Granulosis rubra nasi
  Granulosis rubra nasi
  Granulosis rubra nasi is a rare familial disease of children, occurring on the nose, cheeks, and chin, characterized by diffuse redness, persistent hyperhidrosis, and small dark red papules that disappear on diascopic pressure....
  
   
  
• Green nails
  Green nails
  Green nails may be due to a Pseudomonas aeruginosa infection causing a green nail syndrome or the result of copper in tap water....
  
  
• Gustatory hyperhidrosis
  Gustatory hyperhidrosis
  Gustatory hyperhidrosis is excessive sweating that certain individuals regularly experience on the forehead, upper lip, perioral region, or sternum a few moments after eating spicy foods, tomato sauce, chocolate, coffee, tea, or hot soups....
  
  
• Hair casts
  Hair casts
  Hair casts represent remnants of the inner root sheath, and often occur in great numbers and may mimic nits in the scalp....
  
   (Pseudonits)
• Hair follicle nevus
  Hair follicle nevus
  Hair follicle nevus is a cutaneous condition that presents as a small papule from which fine hairs protrude evenly from the surface....
  
   (Vellus hamartoma)
• Hairy palms and soles
  Hairy palms and soles
  Hairy palms and soles are both a type of cutaneous condition characterized by a hereditary hypertrichosis affecting the palms and soles. This condition is inherited in an autosomal dominant fashion....
  
  
• Half and half nails
  Half and half nails
  Half and half nails show the proximal portion of the nail white and the distal half red, pink, or brown, with a sharp line of demarcation between the two halves. Seventy percent of hemodialysis patients and 56% of renal transplant patients have at least one type of nail abnormality...
  
   (Lindsay's nails)
• Hangnail
  Hangnail
  A hangnail or agnail is a small, torn piece of skin on a fingernail or toenail. Unlike whitlows, hangnails are usually caused by dry skin or nail biting, and may be prevented with proper moisturization of the skin....
  
  
• Hapalonychia
  Hapalonychia
  Hapalonychia is characterized by softened nails resulting from a defect in the matrix that makes the nails thin and soft so that they can be easily bent....
  
  
• Hematidrosis
  Hematidrosis
  Hematidrosis is a very rare condition in which a human being sweats blood. It may occur when a person is suffering extreme levels of stress, for example, facing his or her own death...
  
  
• Hirsutism
  Hirsutism
  Hirsutism or frazonism is the excessive hairiness on women in those parts of the body where terminal hair does not normally occur or is minimal - for example, a beard or chest hair. It refers to a male pattern of body hair and it is therefore primarily of cosmetic and psychological concern...
  
  
• Hook nail
  Hook nail
  Hook nail is a bowing of the nail bed due to a lack of support from the short bony phalanx....
  
  
• Hot comb alopecia
  Hot comb alopecia
  Hot comb alopecia was first reported in the late 1960s as a scarring alopecia seen in black women who straightened their hair with hot combs for cosmetic purposes, developing characteristically on the crown and spreading peripherally to form a large oval area of partial hair loss....
  
  
• Hypertrichosis cubiti
  Hypertrichosis cubiti
  Hypertrichosis cubiti is a cutaneous conditions characterized by multiple terminal hairs on both elbows in children....
  
   (Hairy elbow syndrome)
• Hypertrichosis simplex of the scalp
  Hypertrichosis simplex of the scalp
  Hypertrichosis simplex of the scalp is a cutaneous condition caused by defects in the corneodesmosin protein...
  
  
• Intermittent hair–follicle dystrophy
• Keratosis pilaris atropicans
  Keratosis pilaris atropicans
  Keratosis pilaris atropicans includes many forms of keratosis pilaris with cicatricial alopecia. Variants include keratosis pilaris atrophicans faciei, atrophoderma vermiculatum, keratosis follicularis spinulosa decalvans, and ichthyosis follicularis....
  
  
• Kinking hair
  Kinking hair
  Kinking hair is a condition primarily reposted in postpubescent males with androgenetic alopecia, presenting with gradual curling and darkening of the frontal, temporal, auricular, and vertex hairs which, under the microscope, show kinks and twists with or without longitudinal grooving....
  
   (Acquired progressive kinking)
• Koenen's tumor
  Koenen's tumor
  Koenen's tumor is a cutaneous condition that results in fifty percent of tuberous sclerosis cases....
  
   (Koenen's periungual fibroma, Periungual fibroma)
• Koilonychia
  Koilonychia
  Koilonychia is a nail disease that can be a sign of hypochromic anemia, especially iron-deficiency anemia. Koilonychia literally means "spoon nails." It refers to abnormally thin nails which have lost their convexity, becoming flat or even concave in shape...
  
   (Spoon nails)
• Kyrle disease
  Kyrle disease
  Kyrle disease was first described in J. Kyrle in 1916, characterized by numerous up to cherry-sized hyperkeratotic, verrucous, clefted papules and nodules involving almost the entire skin.-See also:* Josef Kyrle* Cutaneous perforating disorders...
  
  
• Leukonychia
  Leukonychia
  Leukonychia , also known as white nails, is a medical term for white discoloration appearing on nails. It is derived from the Greek words leuko and onyx...
  
   (White nails)
• Lichen planopilaris
  Lichen planopilaris
  Lichen planopilaris is a form of hair loss which involves scarring, a follicular form of lichen planus, and is considered to have an autoimmune cause...
  
   (Acuminatus, Follicular lichen planus, Lichen planus follicularis, Peripilaris)
• Lichen planus of the nails
• Lichen spinulosus
  Lichen spinulosus
  Lichen spinulosus is a rare skin disorder characterized by follicular keratotic papules that are grouped into large patches. It is a variant of keratosis pilaris.-External links:* *...
  
   (Keratosis spinulosa)
• Lipedematous alopecia
  Lipedematous alopecia
  Lipedematous alopecia is a term used to describe a disorder characterized by a thick boggy scalp and hair loss....
  
   (Lipedematous scalp)
• Localized acquired hypertrichosis
• Localized congenital hypertrichosis
• Longitudinal erythronychia
  Longitudinal erythronychia
  Longitudinal erythronychia presents with longitudinal red bands in the nail plate that commence in the matrix and extend to the point of separation of the nail plate and nailbed, and may occur on multiple nails with inflammatory conditions such as lichen planus or Darier's disease....
  
  
• Longitudinal melanonychia
• Loose anagen syndrome
  Loose anagen syndrome
  Loose anagen syndrome is primarily described in fair-haired children who have easily dislodgable hair....
  
   (Loose anagen hair syndrome)
• Lupus erythematosus
  Lupus erythematosus
  Lupus erythematosus is a category for a collection of diseases with similar underlying problems with immunity . Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs...
  
  
• Madarosis
  Madarosis
  Madarosis is the absence or loss of the eyelashes , either as a congenital condition or as a result of an infection.E.g. Leprosy,alopecia totalis etc....
  
  
• Malalignment of the nail plate
  Malalignment of the nail plate
  Malalignment of the nail plate is a congenital malalignment of the nail of the great toe, and is often misdiagnosed even though it is a common condition....
  
  
• Male-pattern baldness
• Marie–Unna hereditary hypotrichosis (Marie–Unna hypotrichosis)
• Median nail dystrophy
  Median nail dystrophy
  Median nail dystrophy consists of longitudinal splitting or canal formation in the midline of the nail, a split which often resembles a fir tree, occurring at the cuticle and proceeding outward as the nail grows.Thumbs, which are the most commonly involved, usually show...
  
   (Dystrophia unguis mediana canaliformis, Median canaliform dystrophy of Heller, Solenonychia)
• Mees' lines
  Mees' lines
  Mees' lines or Aldrich-Mees' lines are lines of discoloration across the nails of the fingers and toes.- Causes :Mees' lines appear after an episode of poisoning with arsenic, thallium or other heavy metals, and can also appear if the subject is suffering from renal failure.- Presentation :They are...
  
  
• Melanonychia
  Melanonychia
  Melanonychia is a black or brown pigmentation of the normal nail plate, and may be present as a normal finding on many digits in black patients, as a result of trauma, systemic disease, or medications, or as a postinflammatory event from such localized events as lichen planus or fixed drug...
  
  
• Menkes kinky hair syndrome (Kinky hair disease, Menkes disease)
• Monilethrix
  Monilethrix
  Monilethrix is a rare autosomal dominant hair disease that results in short, fragile, broken hair that appears beaded. It comes from the Latin word for necklace and the Greek word for hair ....
  
   (Beaded hair)
• Muehrcke's nails (Muehrcke's lines)
• Nail–patella syndrome (Fong syndrome, Hereditary osteoonychodysplasia)
• Neoplasms of the nailbed
  Neoplasms of the nailbed
  Neoplasms of the nailbed may often present with paronychia, ingrown nail, onycholysis, pyogenic granuloma, nail-plate dystrophy, longitudinal erythronychia, bleeding, and discolorations...
  
  
• Nevoid hypertrichosis
  Nevoid hypertrichosis
  Nevoid hypertrichosis is a cutaneous condition characterized by the growth of terminal hairs in a circumscribed area....
  
  
• Noncicatricial alopecia
  Noncicatricial alopecia
  -Causes:Causes of noncicatricial alopecia include:*Alopecia areata*Anagen effluvium*Androgenetic alopecia*Dermatopathia pigmentosa reticularis*Telogen effluvium*Trichotillomania...
  
  
• Onychauxis
  Onychauxis
  Onychauxis presents with thickened nails without deformity, and this simple thickening may be the result of trauma, acromegaly, Darier's disease, psoriasis, or pityriasis rubra pilaris, or, in some cases, hereditary.-References:...
  
  
• Onychoatrophy
  Onychoatrophy
  Onychoatrophy is a faulty underdevelopment of the nail that may be congenital or acquired, in which the nail is thinned and smaller....
  
  
• Onychocryptosis (Ingrown nail, Unguis incarnatus)
• Onychogryphosis
  Onychogryphosis
  Onychogryphosis is a hypertrophy that may produce nails resembling claws or a ram's horn, possibly caused by trauma or peripheral vascular disorders, but most often secondary to neglect and failure to cut the nails for extended periods of time...
  
   (Ram's horn nails)
• Onycholysis
  Onycholysis
  Onycholysis refers to the detachment of the nail from the nail bed, starting at its distal and/or lateral attachment. It is said to occur particularly on the ring finger but can occur on any of the fingernails. The most common cause of onycholysis is psoriasis. It can also occur in thyrotoxicosis...
  
  
• Onychomadesis
  Onychomadesis
  Onychomadesis is a periodic idiopathic shedding of the nails beginning at its proximal end, possibly caused by the temporary arrest of the function of the nail matrix....
  
  
• Onychomatricoma
  Onychomatricoma
  Onychomatricoma is a cutaneous condition characterized by a distinctive tumor of the nail matrix.This nail disease can mimic many nail problems and should be examined and biopsied by a dermatologist. In particular, a main concern is the malignant and destructive potential that may exist. - See...
  
  
• Onychophagia (Nail biting)
• Onychophosis
  Onychophosis
  Onychophosis is a localized or diffuse hyperkeratotic tissue that develops on the lateral or proximal nailfolds, within the space between the nailfolds and the nail plate, and is a common finding in the elderly. Onychophosis may involve the subungual area, as a direct result of repeated minor...
  
  
• Onychoptosis defluvium
  Onychoptosis defluvium
  Onychoptosis defluvium is casting off of the nail seen in association with alopecia areata....
  
   (Alopecia unguium)
• Onychorrhexis
  Onychorrhexis
  Onychorrhexis, also known as Brittle nails, is a brittleness with breakage of finger or toenails that may result from excessive strong soap and water exposure, nail polish remover, hypothyroidism, anemia, anorexia nervosa or bulimia, or after oral retinoid therapy. Onychorrhexis affects up to 20%...
  
   (Brittle nails)
• Onychoschizia
  Onychoschizia
  Onychoschizia is a splitting of the distal nail plate into layers at the free edge, a very common problem among women and represents a dyshesion of the layers of keratin, possible as a result of dehydration....
  
  
• Onychotillomania
  Onychotillomania
  Onychotillomania is a compulsive neurosis in which a person picks constantly at the nails or tries to tear them off. It is not the same as onychophagia, where the nails are bitten or chewed or dermatillomania, where skin is bitten or scratched....
  
  
• Ophiasis
  Ophiasis
  Ophiasis is a form of alopecia areata characterized by the loss of hair in the shape of a wave at the circumference of the head. It gets its name from "ophis", which is the Greek word for snake, because of the apparent similarity to a snake-shape and the pattern of hair loss.The term "sisaipho" is...
  
  
• Palmoplantar hyperhidrosis
  Palmoplantar hyperhidrosis
  Palmoplantar hyperhidrosis is excessive sweating usually localized to the palms, soles, and/or axillae, and may be worse during warm temperatures....
  
   (Emotional hyperhidrosis)
• Parakeratosis pustulosa
  Parakeratosis pustulosa
  Parakeratosis pustulosa is a cutaneous condition which is exclusively seen in children, usually involving one finger, most commonly the thumb or index finger, with the affected nail showing subungual hyperkeratosis and onycholysis....
  
  
• Patterned acquired hypertrichosis
• Perforating folliculitis
  Perforating folliculitis
  Perforating folliculitis is characterized by discrete follicular keratotic eruptions involving mainly the hairy parts of the extremities....
  
  
• Pili annulati
  Pili annulati
  Pili annulati is a peculiar disease in which the hair seems banded by alternating segments of light and dark color when seen in reflected light.- References :...
  
   (Ringed hair)
• Pili bifurcati
  Pili bifurcati
  Pili bifurcati is characterized by bifurcation found in short segments along the shafts of several hairs, with each branch of the bifurcation being covered with its own cuticle.- See also :* Ringed hair* List of cutaneous conditions...
  
  
• Pili multigemini
  Pili multigemini
  Pili multigemini is a rare malformation characterized by the presence of bifurcated or multiple divided hair matrices and papillae, giving rise to the formation of multiple hair shafts within the individual follicles.- References :...
  
  
• Pili pseudoannulati
  Pili pseudoannulati
  Pili pseudoannulati is an anomaly of human hair that mimics pili annulati; however, the two differ in that the light bands of pili annulati are caused by internal effects, whereas the bright segments of pili pseudoannulati are caused by reflection and refraction of light by flattened, twisted...
  
   (Pseudo pili annulati)
• Pili torti
  Pili torti
  Pili torti is characterized by short and brittle hairs that appear flattened and twisted when viewed through a microscope.This phenotype is noted in Menkes disease....
  
   (Twisted hairs)
• Pincer nails
  Pincer nails
  Pincer nails are a toenail disorder in which the lateral edges of the nail slowly approach one another, compressing the nailbed and underlying dermis. It occurs less often in the fingernails and, surprisingly, is usually asymptomatic....
  
   (Omega nails, Trumpet nails)
• Pityriasis amiantacea
  Pityriasis amiantacea
  Pityriasis amiantacea is an eczematous condition of the scalp resulting in hair loss in which thick tenaciously adherent scale infiltrates and surrounds the base of a group of scalp hairs....
  
   (Tinea amiantacea)
• Platonychia
  Platonychia
  Platonychia is characterized by an abnormally flat and broad nail, and may be seen as part of an autosomal-dominant condition in which multiple nail abnormalities are present in many members of a large family....
  
  
• Plica neuropathica
  Plica neuropathica
  Plica neuropathica is a curling, looping, intertwisting, and felting or matting of the hair in localized areas of the scalp....
  
   (Felted hair)
• Plummer's nail
  Plummer's nail
  Plummer's nail is a clinical sign in which there is onycholysis, or separation of the nail from the nail bed, particularly affecting the ring and little fingers. It occurs in patients with thyrotoxicosis.The sign is named after Henry Stanley Plummer....
  
  
• Prepubertal hypertrichosis
  Prepubertal hypertrichosis
  Prepubertal hypertrichosis is a cutaneous condition characterized by increased hair growth, and is a relatively common finding in otherwise healthy infants and children, most often occurring in individuals of Mediterranean or South Asian descent....
  
  
• Pressure alopecia
  Pressure alopecia
  Pressure alopecia occurs in adults after prolonged pressure on the scalp during general anesthesia, with the head fixed in one position, and may also occur in chronically ill persons after prolonged bed rest in one position that causes persistent pressure on one part of the scalp, all likely due...
  
   (Postoperative alopecia, Pressure-induced alopecia)
• Pseudofolliculitis barbae
  Pseudofolliculitis barbae
  Pseudofolliculitis barbae , also known as barber's itch, folliculitis barbae traumatica, razor bumps, scarring pseudofolliculitis of the beard, and shave bumps, is a medical term for persistent irritation caused by shaving....
  
   (Barber's itch, Folliculitis barbae traumatica, Razor bumps, Scarring pseudofolliculitis of the beard, Shave bumps)
• Pseudopelade of Brocq
  Pseudopelade of Brocq
  Pseudopelade of Brocq is a flesh- to pink-colored, irregularly shaped alopecia that may begin in a moth-eaten pattern with eventual coalescence into larger patches of alopecia.-See also:* Cicatricial alopecia...
  
   (Alopecia cicatrisata)
• Psoriatic nails
  Psoriatic nails
  Psoriatic nails is a nail disease. It is common in those suffering from psoriasis, with reported incidences varying from 10% to 78%. Elderly patients and those with psoriatic arthritis are more likely to have psoriatic nails.-Symptoms:...
  
  
• Pterygium inversum unguis
  Pterygium inversum unguis
  Pterygium inversum unguis is characterized by the adherence of the distal portion of the nailbed to the ventral surface of the nail plate...
  
   (Pterygium inversus unguis, Ventral pterygium)
• Pterygium unguis
  Pterygium unguis
  Pterygium unguis forms as a result of scarring between the proximal nailfold and matrix, with the classic example being lichen planus, though it has been reported to occur as a result of sarcoidosis and Hansen's disease....
  
   (Dorsal pterygium)
• Purpura of the nail bed
• Racquet nail (Brachyonychia, Nail en raquette, Racquet thumb)
• Recurrent palmoplantar hidradenitis
  Recurrent palmoplantar hidradenitis
  Recurrent palmoplantar hidradenitis is primarily a disorder of healthy children and young adults, characterized by lesions that are primarily painful, subcutaneous nodules on the plantar surface, resembling...
  
   (Idiopathic palmoplantar hidradenitis, Idiopathic plantar hidradenitis, Painful plantar erythema, Palmoplantar eccrine hidradenitis, Plantar panniculitis)
• Red lunulae
  Red lunulae
  Red lunulae is characterized by a dusky erythema confined to the lunulae, as has been reported in association with alopecia areata....
  
  
• Ross' syndrome
• Rubinstein–Taybi syndrome
• Setleis syndrome
  Setleis syndrome
  Setleis syndrome is a cutaneous condition characterized double upper and absent lower lashes....
  
  
• Shell nail syndrome
  Shell nail syndrome
  Shell nail syndrome is characterized by a nail that resembles a clubbed nail, but in which the nail bed is atrophic instead of being bulbous proliferation of the soft tissue, described in association with bronchiectasis....
  
  
• Short anagen syndrome
  Short anagen syndrome
  Short anagen syndrome is a condition where hair does not grow beyond a short length, due to an unusually short duration of active hair growth . Most cases are associated with fine blond hair....
  
  
• Splinter hemorrhage
  Splinter hemorrhage
  Splinter hemorrhages are tiny lines that run vertically under nails. Splinter hemorrhage is a nonspecific finding and can be associated with subacute bacterial endocarditis, scleroderma, trichinosis, Systemic lupus erythematosus , rheumatoid arthritis, psoriatic nails, antiphospholipid syndrome,...
  
  
• Spotted lunulae
  Spotted lunulae
  -References:*Cohen PR: The Lunula. J Am Acad Dermatol 1996;34:943.*Shelley WB: The spotted lunula: a neglected nail sign with alopecia areata. J Am Acad Dermatol 1980;2:385....
  
  
• Staining of the nail plate
  Staining of the nail plate
  Staining of the nail plate may occur due to nicotine, dyes , potassium permanganate, mercury compounds, hydroquinone, elemental iron, mepacrine, photographic developer, anthralin, chrysarobin, glutaraldehyde, or resorcin....
  
  
• Stippled nails
  Stippled nails
  Stippled nails are characterized by small, pinpoint depressions in an otherwise normal nail, and may be an early change seen in psoriasis....
  
  
• Subungual hematoma
  Subungual hematoma
  A subungual hematoma is a collection of blood underneath a toenail or fingernail . It can be extremely painful for an injury of its size although otherwise it is not a serious medical condition...
  
  
• Telogen effluvium
  Telogen effluvium
  Telogen effluvium is a scalp disorder characterized by thinning/shedding of hair resulting from the early entry of hairs into the telogen phase.Emotional or physiological stressful events may result in an alteration of the normal hair cycle....
  
  
• Terry's nails
  Terry's nails
  Terry's nails is a physical finding in which fingernails and/or toenails appear white with a characteristic "ground glass" appearance, with no lunula. The condition is thought to be due to a decrease in vascularity and an increase in connective tissue within the nail bed...
  
  
• Traction alopecia
  Traction alopecia
  Traction alopecia is a form of alopecia, or gradual hair loss, caused primarily by pulling force being applied to the hair. This commonly results from the sufferer frequently wearing his/her hair in a particularly tight ponytail, pigtails, or braids...
  
  
• Traumatic alopecia
  Traumatic alopecia
  Traumatic alopecia is a cutaneous condition that results from the forceful pulling out of the scalp hair....
  
  
• Traumatic anserine folliculosis
  Traumatic anserine folliculosis
  Traumatic anserine folliculosis is a curious gooseflesh-like follicular hyperkeratosis that may result from persistent pressure and lateral friction of one skin surface against another....
  
  
• Triangular alopecia
  Triangular alopecia
  Triangular alopecia is hair loss that may be congenital but usually appears in childhood as a focal patch of loss that may be complete or leaving fine vellus hairs behind....
  
   (Temporal alopecia, Temporal triangular alopecia)
• Trichomegaly
• Trichomycosis axillaris
  Trichomycosis axillaris
  Trichomycosis axillaris is a superficial bacterial colonization of the hair shafts in sweat gland–bearing areas, such as the armpits and the pubic area...
  
  
• Trichorrhexis invaginata
  Trichorrhexis invaginata
  Trichorrhexis invaginata is a distinctive hair shaft abnormality that may occur sporadically, either in normal hair or with other hair shaft abnormalities, or regularly as a marker for Netherton's syndrome...
  
   (Bamboo hair)
• Trichorrhexis nodosa
  Trichorrhexis nodosa
  Trichorrhexis nodosa is a defect in the hair shaft characterized by thickening or weak points that cause the hair to break off easily. This group of conditions contributes to the appearance of hair loss, lack of growth, and damaged-looking hair....
  
  
• Trichostasis spinulosa
  Trichostasis spinulosa
  Trichostasis spinulosa is a common disorder of the hair follicles that clinically gives the impression of blackheads, but the follicles are filled with funnel-shaped, horny plugs which are bundles of vellus hairs....
  
  
• Tufted folliculitis
  Tufted folliculitis
  Tufted folliculitis presents with doll's hair-like bundling of follicular units, and is seen in a wide range of scarring conditions including chronic staphylococcal infection, chronic lupus erythematosus, lichen planopilaris, Graham-Little syndrome, folliculitis decalvans, acne keloidalis nuchae,...
  
  
• Tumor alopecia
  Tumor alopecia
  Tumor alopecia refers to the hair loss in the immediate vicinity of either benign or malignant tumors of the scalp....
  
  
• Twenty-nail dystrophy (Sandpapered nails, Trachyonychia)
• Uncombable hair syndrome
  Uncombable hair syndrome
  Uncombable hair syndrome, also known as Pili trianguli et canaliculi, Spun-glass hair, and Cheveux incoiffables, is a rare structural anomaly of the hair with a variable degree of effect. It was discovered in the 1970s...
  
   (Cheveux incoiffable, Pili trianguli et canaliculi, Spun-glass hair)
• Wooly hair
  Wooly hair
  Wooly hair is the presence of hair typical of those of sub-Saharan ancestry on people from other ethnic backgrounds, hair which, under the microscope, appears tightly coiled, and presents at birth or infancy usually as a solitary inherited trait in an autosomal dominant fashion.- See also :* Wooly...
  
   (Woolly hair)
• Wooly hair nevus (Woolly hair nevus)
• X-linked hypertrichosis
  X-linked hypertrichosis
  X-linked hypertrichosis is a hereditary disorders characterized by generalized congenital hypertrichosis....
  
  

Conditions of the subcutaneous fat

Conditions of the subcutaneous fat

Subcutaneous tissue

The hypodermis, also called the hypoderm, subcutaneous tissue, or superficial fascia is the lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages...

 are those affecting the layer of adipose tissue

Adipose tissue

In histology, adipose tissue or body fat or fat depot or just fat is loose connective tissue composed of adipocytes. It is technically composed of roughly only 80% fat; fat in its solitary state exists in the liver and muscles. Adipose tissue is derived from lipoblasts...

 that lies between the dermis

Dermis

The dermis is a layer of skin between the epidermis and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis...

 and underlying fascia

Fascia

A fascia is a layer of fibrous tissue that permeates the human body. A fascia is a connective tissue that surrounds muscles, groups of muscles, blood vessels, and nerves, binding those structures together in much the same manner as plastic wrap can be used to hold the contents of sandwiches...

.

• Acquired generalized lipodystrophy
  Acquired generalized lipodystrophy
  Acquired generalized lipodystrophy is a rare skin condition that appears during childhood or adolescence, characterized by fat loss affecting large areas of the body, particularly the face, arms, and legs....
  
   (Lawrence syndrome, Lawrence–Seip syndrome)
• Adiposis dolorosa
  Adiposis dolorosa
  Adiposis dolorosa, also known as Dercum's Disease is a rare condition characterized by multiple, painful lipomas. These lipomas mainly occur on the trunk, the upper arms and upper legs. The diagnosis of Dercum's disease implies a long, chronic pain syndrome of debilitating nature...
  
   (Dercum's disease)
• Alpha-1 antitrypsin deficiency panniculitis
  Alpha-1 antitrypsin deficiency panniculitis
  Alpha-1 antitrypsin deficiency panniculitis is a skin condition characterized by inflammation of the subcutaneous fat associated with a deficiency of the α1-antitrypsin enzyme.- See also :* Panniculitis* Skin lesion* List of cutaneous conditions* Alpha-1 antitrypsin deficiency...
  
   (Alpha1-protease deficiency panniculitis, Alpha1-proteinase deficiency panniculitis)
• Atrophic connective tissue panniculitis
  Atrophic connective tissue panniculitis
  Atrophic connective tissue panniculitis is a rare condition, and often occurs on the upper or lower extremities....
  
  
• Barraquer–Simons syndrome (Acquired partial lipodystrophy, Cephalothoracic lipodystrophy, Progressive lipodystrophy)
• Benign symmetric lipomatosis
  Benign symmetric lipomatosis
  Benign symmetric lipomatosis is a cutaneous condition characterized by extensive symmetric fat deposits in the head, neck, and shoulder girdle area...
  
   (Benign symmetric lipomatosis of Launois–Bensaude, Madelung's disease)
• Centrifugal abdominal lipodystrophy
  Centrifugal abdominal lipodystrophy
  Centrifugal abdominal lipodystrophy is a skin condition characterized by areas of subcutaneous fat loss that slowly enlarge....
  
   (Centrifugal lipodystrophy, Lipodystrophia centrifugalis abdominalis infantalis)
• Chronic erythema nodosum
  Chronic erythema nodosum
  Chronic erythema nodosum is a form of septal panniculitis that is much less common than acute erythema nodosum....
  
   (Erythema nodosum migrans, Subacute migratory panniculitis of Vilanova and Piñol, Subacute nodular migratory panniculitis)
  
• Cold panniculitis
  Cold panniculitis
  Cold panniculitis is a skin condition characterized by inflammation of the subcutaneous fat after exposure to cold, most often seen in infants and young children. This condition has been described in children who suck ice or popsicles, and therefore is sometimes referred to as "popsicle...
  
   (Popsicle panniculitis)
• Congenital generalized lipodystrophy
  Congenital generalized lipodystrophy
  Congenital generalized lipodystrophy is a rare autosomal dominant skin condition, characterized by an extreme paucity of fat in the subcutaneous tissues.-Genetics:-Presentation:...
  
   (Berardinelli–Seip syndrome)
• Cytophagic histiocytic panniculitis
  Cytophagic histiocytic panniculitis
  Cytophagic Histiocytic Panniculitis was first described in 1980 by Winkelmann as a chronic histiocytic disease of the subcutaneous adipose tissue, which is characterized clinically by tender erythematous nodules, recurrent high fever, malaise, jaundice, organomegaly, serosal effusions,...
  
  
• Drug-induced lipodystrophy
  Drug-induced lipodystrophy
  Drug-induced lipodystrophy is a cutaneous condition that presents as one or multiple depressed areas , usually on the proximal extremities, ranging from under a few centimeters to greater than 20 cm in diameter.- See also :...
  
  
• Factitial panniculitis
  Factitial panniculitis
  Factitial panniculitis is a skin condition characterized by inflammation of the subcutaneous fat that may be indiced by the injection of organic materials, povidone, feces, saliva, vaginal fluid, and oils....
  
  
• Familial partial lipodystrophy
  Familial partial lipodystrophy
  Familial partial lipodystrophy is an autosomal dominant skin condition characterized by the loss of subcutaneous fat.Type 1 is believed to be underdiagnosed.- References :...
  
   (Köbberling–Dunnigan syndrome)
• Gouty panniculitis
  Gouty panniculitis
  Gouty panniculitis is a skin condition characterized by inflammation of the subcutaneous fat caused by deposition of uric acid crystals....
  
  
• Hemihyperplasia–multiple lipomatosis syndrome
  Hemihyperplasia–multiple lipomatosis syndrome
  Hemihyperplasia-multiple lipomatosis syndrome is a cutaneous condition characterized by multiple lipomas in association with asymmetric overgrowth, cutaneous capillary malformations, and thickened plantar skin with prominent creases....
  
  
• HIV-associated lipodystrophy
  HIV-associated lipodystrophy
  HIV-associated lipodystrophy is a condition characterized by loss of subcutaneous fat associated with infection with HIV.-Cause:The exact mechanism of HIV-associated lipodystrophy is not fully elucidated...
  
  Within this list, the terms human immunodeficiency virus
  HIV
  Human immunodeficiency virus is a lentivirus that causes acquired immunodeficiency syndrome , a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive...
  
   and acquired immunodeficiency syndrome
  AIDS
  Acquired immune deficiency syndrome or acquired immunodeficiency syndrome is a disease of the human immune system caused by the human immunodeficiency virus...
  
   are abbreviated to HIV
  HIV
  Human immunodeficiency virus is a lentivirus that causes acquired immunodeficiency syndrome , a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive...
  
   and AIDS
  AIDS
  Acquired immune deficiency syndrome or acquired immunodeficiency syndrome is a disease of the human immune system caused by the human immunodeficiency virus...
  
  , respectively.
• Involutional lipoatrophy
  Involutional lipoatrophy
  Involutional lipoatrophy is a cutaneous condition, and is an idiopathic lipoatrophy characterized clinically by non-inflammatory focal loss of fat...
  
  
• Lipoatrophia annularis
  Lipoatrophia annularis
  Lipoatrophia annularis is a skin condition affecting primarily women, characterized by the loss of subcutaneous fat in the upper extremity.It is a form of lipodystrophy....
  
   (Ferreira–Marques lipoatrophia)
• Lipoatrophia semicircularis
  Lipoatrophia semicircularis
  Lipoatrophia semicircularis is a medical condition in humans, commonly known as ribbed thighs.It consists of a semicircular zone of atrophy of the subcutaneous fatty tissue located mostly on the front of the thighs. Skin and underlying muscles remains intact.Semicircular lipoatrophy mainly affects...
  
   (Semicircular lipoatrophy)
• Lipodermatosclerosis
  Lipodermatosclerosis
  Lipodermatosclerosis is a skin and connective tissue disease. It is a form of lower extremity panniculitis, an inflammation of the layer of fat under the epidermis.- Symptoms :Pain may be the first noticed symptom...
  
   (Chronic panniculitis with lipomembranous changes, Hypodermitis sclerodermiformis, Sclerosing panniculitis, Stasis panniculitis)
• Lipohypertrophy
  Lipohypertrophy
  Lipohypertrophy is a medical term that refers to a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin. It may be unsightly, mildly painful, and may change the timing or completeness of insulin action...
  
  
• Localized lipodystrophy
  Localized lipodystrophy
  Localized lipodystrophy is a skin condition characterized by the loss subcutaneous fat localized to sites of insulin injection....
  
  
• Neutrophilic lobular panniculitis
  Neutrophilic lobular panniculitis
  Neutrophilic lobular panniculitis is a cutaneous condition characterized by inflammation of the subcutaneous fat.- See also :* Bowel-associated dermatosis–arthritis syndrome* List of cutaneous conditions...
  
  
• Nodular vasculitis
  Nodular vasculitis
  Nodular vasculitis is a skin condition characterized by crops of small, tender, erythematous nodules on the legs, mostly on the calves and shins. Miroscopically there are epithelioid granulomas and vasculitis in the subcutaneous tissue, making it a form of panicullitis...
  
  
• Non-progressive late-onset linear hemifacial lipoatrophy
  Non-progressive late-onset linear hemifacial lipoatrophy
  Non-progressive late-onset linear hemifacial lipoatrophy is a cutaneous condition that occurs on the malar cheek, mostly in the elderly population....
  
  
• Pancreatic panniculitis
  Pancreatic panniculitis
  Pancreatic panniculitis is a skin condition most commonly associated with pancreatic carcinoma, and more rarely with anatomic pancreatic abnormalities, pseudocysts, or drug-induced pancreatitis....
  
   (Enzymatic panniculitis, Pancreatic fat necrosis, Subcutaneous fat necrosis)
• Poland's syndrome
• Post-steroid panniculitis
  Post-steroid panniculitis
  Post-steroid panniculitis is a skin condition characterized by inflammation of the subcutaneous fat occurring predominantly in children treated acutely with high doses of systemic corticosteroids during rapid corticosteroid withdrawal....
  
  
• Sclerema neonatorum
  Sclerema neonatorum
  Sclerema neonatorum is a rare a severe skin condition that is characterized by inflammation of the underlying subcutaneous fat.- References :...
  
  
• Sclerosing lipogranuloma
  Sclerosing lipogranuloma
  Sclerosing lipogranuloma is a skin condition characterized by a granulomatous and fibrotic reaction that occurs in the subcutaneous fat from the injection of silicone or mineral oils.- References :...
  
   (Paraffinoma)
• Septal panniculitis
  Septal panniculitis
  Septal panniculitis is a condition of the subcutaneous fat affecting the layer of adipose tissue that lies between the dermis and underlying fascia, of which there are two forms: acute erythema nodosum and chronic erythema nodosum.- See also :...
  
  
• Subcutaneous fat necrosis of the newborn
  Subcutaneous fat necrosis of the newborn
  Subcutaneous fat necrosis of the newborn is a rare form of lobular panniculitis occurring in newborns that is usually self-remitting and non-recurring. Proposed causes include perinatal stress, local trauma, hypoxia and hypothermia, though the exact cause is unknown...
  
  
• Traumatic panniculitis
  Traumatic panniculitis
  Traumatic panniculitis is a skin condition characterized by inflammation and necrosis of the subcutaneous fat following accidental trauma to the skin....
  
  
• Tumor lysis syndrome
  Tumor lysis syndrome
  In medicine , tumor lysis syndrome is a group of metabolic complications that can occur after treatment of cancer, usually lymphomas and leukemias, and sometimes even without treatment...
  
  
• Weber–Christian disease
  Weber–Christian disease
  Weber–Christian disease is a cutaneous condition characterized by recurrent subcutaneous nodules that heal with depression of the overlying skin.It is type of panniculitis....
  
   (Relapsing febrile non-suppurative panniculitis)

Congenital anomalies

Cutaneous congenital anomalies are a diverse group of disorders that result from faulty morphogenesis

Morphogenesis

Morphogenesis , is the biological process that causes an organism to develop its shape...

, the biological process that forms the shape of a human body

Human body

The human body is the entire structure of a human organism, and consists of a head, neck, torso, two arms and two legs.By the time the human reaches adulthood, the body consists of close to 100 trillion cells, the basic unit of life...

.

• Accessory nail of the fifth toe
  Accessory nail of the fifth toe
  The accessory nail of the fifth toe is a physical trait of the small toe, where a minuscule "sixth toenail" is present in the outer corner of the nail situated on the smallest toe...
  
  
• Accessory tragus
  Accessory tragus
  An accessory tragus, ear tag, preauricular appendage or preauricular tag is a relatively common congenital anomaly of the first branchial arch...
  
   (Ear tag, Preauricular appendage, Preauricular tag)
• Amniotic band syndrome
  Amniotic band syndrome
  Amniotic band syndrome is a congenital disorder caused by entrapment of fetal parts in fibrous amniotic bands while in utero.-Epidemiology:Amniotic banding affects approximately 1 in 1,200 live births...
  
   (ADAM complex, Amniotic band sequence, Congenital constriction bands, Pseudoainhum)
• Aplasia cutis congenita
  Aplasia cutis congenita
  Aplasia cutis congenita is the most common congenital cicatricial alopecia, and is a congenital focal absence of epidermis with or without evidence of other layers of the skin....
  
   (Cutis aplasia, Congenital absence of skin, Congenital scars)
• Arteriovenous fistula
  Arteriovenous fistula
  An arteriovenous fistula is an abnormal connection or passageway between an artery and a vein. It may be congenital, surgically created for hemodialysis treatments, or acquired due to pathologic process, such as trauma or erosion of an arterial aneurysm....
  
  
• Benign neonatal hemangiomatosis
  Benign neonatal hemangiomatosis
  Benign neonatal hemangiomatosis is a cutaneous condition and a term reserved for infants with multiple cutaneous lesions without evident visceral hemangiomas....
  
  
• Branchial cyst (Branchial cleft cyst)
• Bronchogenic cyst
  Bronchogenic cyst
  Bronchogenic cysts are small, solitary cysts or sinuses, most typically located in the region of the suprasternal notch or over the manubrium.-Histology:They are lined by respiratory type epithelium, which is characterized by cilia...
  
  
• Capillary hemangioma
  Capillary hemangioma
  A capillary hemangioma appears as a raised, red, lumpy area of flesh anywhere on the body, though 83% occur on the head or neck area. These marks occur in about 10% of all births, and usually appear between one and four weeks after birth. It may grow rapidly, before stopping and slowly fading...
  
   (Infantile hemangioma, Nevus maternus, Strawberry hemangioma Strawberry nevus)
• Cavernous venous malformation
• Congenital cartilaginous rest of the neck
  Congenital cartilaginous rest of the neck
  Congenital cartilaginous rest of the neck is a cutaneous condition characterized by branchial arch remnants that are considered to be the cervical variant of accessory tragus....
  
   (Cervical accessory tragus, Wattle)
• Congenital erosive and vesicular dermatosis
  Congenital erosive and vesicular dermatosis
  Congenital erosive and vesicular dermatosis is a cutaneous condition characterized by generalized erosions, vesicles, crusting and ‘scalded skin-like’ erythematous areas affecting up to 75% of the body surface area....
  
  
• Congenital hypertrophy of the lateral fold of the hallux
  Congenital hypertrophy of the lateral fold of the hallux
  Congenital hypertrophy of the lateral fold of the hallux is a rare cutaneous condition of unknown pathology that present to newborns. The condition was "first described by Martinet et al. in 1984." This sometimes painful condition involves "an overgrowth of the soft tissue" that can partially cover...
  
  
• Congenital lip pit
  Congenital lip pit
  Congenital lip pits are a cutaneous condition that are divided into three types based on their location: commissural; upper lip; and lower lip....
  
   (Congenital sinus of the lower lip, Lip sinus, Midline sinus of the upper lip)
• Congenital malformations of the dermatoglyphs
  Congenital malformations of the dermatoglyphs
  Congenital malformations of the dermatoglyphs are a cutaneous condition divided into four main categories based on the appearance of the dermal ridges of which they are composed: ridge aplasia; ridge hypoplasia; ridge dissociation; and ridges-off-the-end....
  
  
• Congenital smooth muscle hamartoma
  Congenital smooth muscle hamartoma
  Congenital smooth muscle hamartoma is typically a skin colored or lightly pigmented patch or plaque with hypertrichosis....
  
  
• Cystic lymphatic malformation
  Cystic lymphatic malformation
  A Cystic lymphatic malformation is a deep-seated, typically multilocular, ill-defined soft-tissue mass that is painless and covered by normal skin. These malformations may further be divided into macrocystic lymphatic malformations and microcystic lymphatic malformations....
  
  
• Dermoid cyst
  Dermoid cyst
  A dermoid cyst is a cystic teratoma that contains developmentally mature skin complete with hair follicles and sweat glands, sometimes clumps of long hair, and often pockets of sebum, blood, fat, bone, nails, teeth, eyes, cartilage, and thyroid tissue. Because it contains mature tissue, a dermoid...
  
  
• Diffuse neonatal hemangiomatosis
  Diffuse neonatal hemangiomatosis
  Diffuse neonatal hemangiomatosis is a cutaneous condition and a term used to describe infants with multiple cutaneous and systemic hemangiomas....
  
  
• Encephalocele
  Encephalocele
  Encephalocele, sometimes known by the Latin name cranium bifidum, is a neural tube defect characterized by sac-like protrusions of the brain and the membranes that cover it through openings in the skull. These defects are caused by failure of the neural tube to close completely during fetal...
  
  
• Hutchinson's teeth
  Hutchinson's teeth
  Hutchinson's teeth are a sign of congenital syphilis. Babies with this have teeth that are smaller and more widely spaced than normal and which have notches on their biting surfaces...
  
  
• Hyperkeratotic cutaneous capillary-venous malformation
  Hyperkeratotic cutaneous capillary-venous malformation
  Hyperkeratotic cutaneous capillary-venous malformation is a cutaneous condition characterized also by inherited cerebral capillary malformations....
  
  
• Intrauterine epidermal necrosis
  Intrauterine epidermal necrosis
  Intrauterine epidermal necrosis is a cutaneous condition that is rapidly fatal, characterized by skin erosions and ulcerations only....
  
  
• Limb–mammary syndrome
  Limb–mammary syndrome
  -External links:* *...
  
  
• Lowry–MacLean syndrome
  Lowry–MacLean syndrome
  Lowry–MacLean syndrome is a congenital condition that may be characterized by an ear pit....
  
  
• Macrocheilia
  Macrocheilia
  Macrocheilia is a condition of permanent swelling of the lip that results from greatly distended lymphatic spaces. This causes an abnormal largeness of the lips. This is sometimes seen in leprosy patients.-External links:*...
  
  
• Macrocystic lymphatic malformation
  Macrocystic lymphatic malformation
  Macrocystic lymphatic malformations are a cutaneous condition characterized by interconnected, large lymphatic cysts lined by a thin endothelium, commonly called cystic hygromas....
  
  
• Malignant pilomatricoma
  Malignant pilomatricoma
  Malignant pilomatricoma is a cutaneous condition characterized by a locally aggressive tumor composed of hair matrix cells....
  
   (Pilomatrical carcinoma, Pilomatrix carcinoma)
• Maternal autoimmune bullous disease
• Median raphe cyst
  Median raphe cyst
  Median raphe cysts are a cutaneous condition of the penis due to developmental defects near the glans....
  
  
• Melanotic neuroectodermal tumor of infancy
  Melanotic neuroectodermal tumor of infancy
  Melanotic neuroectodermal tumor of infancy is a cutaneous condition that is a developmental disorder present at birth....
  
  
• Membranous aplasia cutis
  Membranous aplasia cutis
  Membranous aplasia cutis is a cutaneous condition, a type of aplasia cutis congenita, which can be seen along the embryonic fusion lines of the face....
  
  
• Microcystic lymphatic malformation
  Microcystic lymphatic malformation
  Microcystic lymphatic malformations are a cutaneous condition characterized by aggregations of ill-defined, abnormal, microscopic lymphatic channels....
  
  
• Midline cervical cleft
  Midline cervical cleft
  Midline cervical clefts are a cutaneous condition, a rare congenital anomaly resulting from incomplete fusion of the branchial arches in the ventral midline of the neck....
  
  
• Mongolian spot
  Mongolian spot
  A Mongolian spot, also known as "Mongolian blue spot," "Congenital dermal melanocytosis," and "Dermal melanocytosis" is a benign, flat, congenital birthmark with wavy borders and irregular shape, discovered on and named after Mongolians by Erwin Bälz. It is also extremely prevalent among East...
  
   (Congenital dermal melanocytosis, Dermal melanocytosis)
  
• Mulberry molar
  Mulberry molar
  Mulberry molars are a dental condition usually associated with congenital syphilis, characterized by multiple rounded rudimentary enamel cusps on the permanent first molars....
  
  
• Nager acrofacial dysostosis
  Nager acrofacial dysostosis
  Nager acrofacial dysostosis is a congenital anomaly syndrome that may be characterized by accessory tragi.Nager Syndrome displays several or all of the following characteristics: underdevelopment of the cheek and jaw area, down-sloping of the opening of the eyes, lack or absence of the lower...
  
  
• Nasal glioma
  Nasal glioma
  Nasal glioma is a rare benign congenital tumor, usually a firm, incompressible, reddish-blue to purple lesion occurring on the nasal bridge or midline near the root....
  
   (Brain-like heterotopia, Cephalic brain-like heterotopia, Glial hamartoma, Heterotopic neuroglial tissue, Nasal cerebral heterotopia, Nasal heterotopic brain tissue)
• Nasolacrimal duct cyst
  Nasolacrimal duct cyst
  Nasolacrimal duct cysts are a cutaneous condition that is a developmental defect present at birth....
  
  
• Nevus psiloliparus
  Nevus psiloliparus
  Nevus psiloliparus is a cutaneous condition, a rare scalp anomaly characterized by a variable degree of alopecia and an excessive amount of adipose tissue....
  
  
• Non-involuting congenital hemangioma
  Non-involuting congenital hemangioma
  Non-involuting congenital hemangioma is a cutaneous condition, lesions occur slightly more often in male infants and are well developed at birth....
  
  
• Omphalomesenteric duct cyst
  Omphalomesenteric duct cyst
  Omphalomesenteric duct cysts are developmental defects relating to the closure of the omphalomesenteric duct. It usually disintegrates within six weeks of gestation, but remnants of the cyst can sometimes be found along the intestines or umbilicus. Any remnants can be removed via surgical means....
  
   (Omphalomesenteric duct remnant, Vitelline cyst)
• Pilomatricoma
  Pilomatricoma
  Pilomatricoma, also known as a calcifying epithelioma of Malherbe, Malherbe calcifying epithelioma, and Pilomatrixoma, is a benign skin tumor derived from the hair matrix.-Histologic features:...
  
   (Calcifying epithelioma of Malherbe, Malherbe calcifying epithelioma, Pilomatrixoma)
• Poland anomaly
  Poland anomaly
  The Poland anomaly is a human developmental problem, and is a predominantly sporadic developmental field defect in which hypoplasia or absence of the nipple and/or breast is associated with ipsilateral aplasia of the sternal head of the pectoralis major muscle, patchy absence of axillary hair, and...
  
  
• Posterior fossa malformations–hemangiomas–arterial anomalies–cardiac defects–eye abnormalities–sternal cleft and supraumbilical raphe syndrome (PHACE association, PHACES syndrome)
• Preauricular sinus and cyst
  Preauricular sinus and cyst
  A preauricular sinus or cyst A preauricular sinus or cyst A preauricular sinus or cyst (also known as a "Congenital auricular fistula," "Congenital preauricular fistula," "Ear pit", and "Preauricular cyst"...
  
   (Ear pit, Congenital auricular fistula, Congenital preauricular fistula, Ear pit, Preauricular cyst)
• Rapidly involuting congenital hemangioma
  Rapidly involuting congenital hemangioma
  A Rapidly involuting congenital hemangioma is a cutaneous condition characterized by a fully developed congenital hemangioma at birth....
  
   (Congenital non-progressive hemangioma)
• Rosenthal–Kloepfer syndrome
  Rosenthal–Kloepfer syndrome
  Rosenthal–Kloepfer syndrome is a cutaneous condition characterized by congenital dermatoglyph malformations.It was characterized in 1962....
  
  
• Rudimentary supernumerary digit (Rudimentary polydactyly)
• Sinus pericranii
  Sinus pericranii
  Sinus pericranii is a rare disorder characterized by a congenital epicranial venous malformation of the scalp. Sinus pericranii is an abnormal communication between the intracranial and extracranial venous drainage pathways...
  
  
• Skin dimple
  Skin dimple
  Skin dimples are deep cutaneous depressions that are seen most commonly on the cheeks or chin, occurring in a familial pattern suggestive of autosomal dominant inheritance....
  
   (Skin fossa)
• Superficial lymphatic malformation
  Superficial lymphatic malformation
  Superficial lymphatic malformation is a congenital malformation of the superficial lymphatics, presenting as groups of deep-seated, vesicle-like papules resembling frog spawn, at birth or shortly thereafter....
  
   (Lymphangioma circumscriptum)
• Supernumerary nipple
  Supernumerary nipple
  A supernumerary nipple is an additional nipple occurring in mammals, including humans...
  
   (Accessory nipple, Pseudomamma)
• Thyroglossal duct cyst
• Verrucous vascular malformation
  Verrucous vascular malformation
  Verrucous vascular malformation is a malformation of dermal and subcutaneous capillaries and veins, a congenital vascular malformation, which, over time, a verrucous component appears....
  
   (Angiokeratoma circumscriptum naeviforme)

Connective tissue diseases

Connective tissue diseases are caused by a complex array of autoimmune responses that target or affect collagen

Collagen

Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content...

 or ground substance

Ground substance

Ground substance is a term for the non-cellular components of extracellular matrix which contain the fibers.It is usually not visible on slides, because it is removed during the preparation process....

.

• Acute cutaneous lupus erythematosus
  Acute cutaneous lupus erythematosus
  Acute cutaneous lupus erythematosus is a cutaneous condition characterized by a bilateral malar erythema and lesions that tend to be transient, follow sun exposure....
  
  
• Atrophoderma of Pasini and Pierini
  Atrophoderma of Pasini and Pierini
  Atrophoderma of Pasini and Pierini is a disease characterized by large lesions with a sharp peripheral border dropping into a depression with no outpouching, which, on biopsy, elastin is normal, while collagen may be thickened...
  
   (Dyschromic and atrophic variation of scleroderma, Morphea plana atrophica, Sclérodermie atrophique d'emblée)
• Calcinosis–Raynaud phenomenon–esophageal dysmotility–sclerodactyly–telangiectasia syndrome (CREST syndrome)
• Chilblain lupus erythematosus
  Chilblain lupus erythematosus
  Chilblain lupus erythematosus is a chronic, unremitting form of lupus erythematosus with the fingertips, rims of ears, calves, and heels affected, especially in women....
  
   (Chilblain lupus erythematosus of Hutchinson)
• Childhood dermatomyositis
  Childhood dermatomyositis
  Childhood dermatomyositis is a connective-tissue disease related to polymyositis, characterized by inflammation of the muscles and the skin. It differs from adult dermatomyositis in several ways, and has two common variants. The more common form is the "Brunsting type," in which slow, progressive...
  
  
• Childhood discoid lupus erythematosus
• Childhood systemic lupus erythematosus 
• Complement deficiency syndromes
• Dermatomyositis
  Dermatomyositis
  Dermatomyositis is a connective-tissue disease related to polymyositis and Bramaticosis that is characterized by inflammation of the muscles and the skin.- Causes :...
  
  
• Eosinophilia–myalgia syndrome
• Frontal linear scleroderma
  Frontal linear scleroderma
  Frontal linear scleroderma is a type of linear scleroderma characterized by a linear band of atrophy and a furrow in the skin that occurs in the frontal or frontoparietal scalp...
  
   (En coup de sabre, Morphea en coup de sabre)
• Generalized discoid lupus erythematosus
• Generalized morphea
  Generalized morphea
  Generalized morphea is characterized by widespread indurated plaques and pigmentary changes, sometimes associated with muscle atrophy, but without visceral involvement....
  
  
• Interstitial granulomatous dermatitis
  Interstitial granulomatous dermatitis
  Interstitial granulomatous dermatitis with arthritis is a condition that most commonly presents with symmetrical round-to-oval erythematous or violaceous plaques on the flanks, axillae, inner thighs, and lower abdomen....
  
  
• Juvenile rheumatoid arthritis (Juvenile idiopathic arthritis, Still's disease)
• Keloid morphea
• Linear atrophoderma of Moulin
  Linear atrophoderma of Moulin
  Linear atrophoderma of Moulin is an acquired unilateral dermatitis localized along the Blaschko lines. It affects children or adolescents of both genders, involving the trunk and the limbs. It is, presumably, a rare cutaneous form of mosaicism...
  
   (Moulin atrophoderma linearis)
• Linear scleroderma
  Linear scleroderma
  Linear scleroderma is a type of localized scleroderma which is an auto-immune disorder characterized by a line of thickened skin which can affect the bones and muscles underneath it.-Presentation:...
  
  
• Localized discoid lupus erythematosus
• Localized morphea
  Localized morphea
  Localized morphea is a form of scleroderma that is twice as common in women as in men, occurs in childhood as well as in adult life, and most often presents as macules or plaques a few centimeters in diameter, but also may occur as bands or in guttate lesions or nodules....
  
  
• Lupus erythematosus panniculitis
  Lupus erythematosus panniculitis
  Lupus erythematosus panniculitis presents with subcutaneous nodules that are commonly firm, sharply defined, and nontender....
  
   (Lupus erythematosus profundus, Lupus panniculitis, Lupus profundus, Subcutaneous lupus erythematosus)
• Lupus erythematosus–lichen planus overlap syndrome (Lichen planus–lupus erythematosus overlap syndrome)
• Methotrexate-induced papular eruption
  Methotrexate-induced papular eruption
  Methotrexate-induced papular eruption appears in patients being treated with methotrexate, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities....
  
  
• Mixed connective tissue disease
  Mixed connective tissue disease
  In medicine, mixed connective tissue disease , commonly abbreviated as MCTD, is an autoimmune disease, in which the body's defense system attacks itself. It was characterized in 1972....
  
   (Sharp's syndrome, Undifferentiated connective tissue disease)
• Morphea profunda
  Morphea profunda
  Morphea profunda involves deep subcutaneous tissue, including fascia, and there is a clinical overlap with eosinophilic fasciitis, eosinophilia-myalgia syndrome, and the Spanish toxic oil syndrome. Morphea profunda shows little response to corticosteroids and tends to run a more chronic...
  
  
• Morphea–lichen sclerosus et atrophicus overlap
• Mouth and genital ulcers with inflamed cartilage syndrome
  Mouth and genital ulcers with inflamed cartilage syndrome
  Mouth and genital ulcers with inflamed cartilage syndrome is a cutaneous condition with features of both Behçet's disease and relapsing polychondritis....
  
   (MAGIC syndrome)
• Neonatal lupus erythematosus
  Neonatal lupus erythematosus
  Neonatal lupus erythematosus is the occurrence of SLE symptoms in an infant born from a mother with SLE, most commonly presenting with a rash resembling discoid lupus erythematosus, and sometimes with systemic abnormalities such as heart block or hepatosplenomegaly.The infants have no skin lesions...
  
  
• Nephrogenic systemic fibrosis
  Nephrogenic systemic fibrosis
  Nephrogenic systemic fibrosis or nephrogenic fibrosing dermopathy is a rare and serious syndrome that involves fibrosis of skin, joints, eyes, and internal organs. Its cause is not fully understood...
  
   (Nephrogenic fibrosing dermopathy)
• Nicolau–Balus syndrome
  Nicolau–Balus syndrome
  Nicolau–Balus syndrome is a cutaneous condition characterized by syringomas and milia....
  
   
  
• Nodulosis–arthropathy–osteolysis syndrome
  Nodulosis–arthropathy–osteolysis syndrome
  Nodulosis–arthropathy–osteolysis syndrome is a cutaneous condition that shares features with juvenile hyaline fibromatosis....
  
  
• Normophosphatemic familial tumoral calcinosis
  Normophosphatemic familial tumoral calcinosis
  Normophosphatemic familial tumoral calcinosis is a cutaneous disorder characterized by cutaneous calcification or ossification....
  
  
• Palisaded neutrophilic and granulomatous dermatitis
• Pansclerotic morphea
  Pansclerotic morphea
  Pansclerotic morphea is manifested by sclerosis of the dermis, panniculus, fascia, muscle, and at times, the bone, all causing disabling limitation of motion of joints....
  
  
• Parry–Romberg syndrome (Progressive hemifacial atrophy)
• Progressive systemic sclerosis
  Progressive systemic sclerosis
  Progressive systemic sclerosis is a generalized disorder of connective tissue in which there is thickening of dermal collagen bundles, and fibrosis and vascular abnormalities in internal organs....
  
  
• Relapsing polychondritis (Atrophic polychondritis, Systemic chondromalacia)
• Rheumatoid arthritis
  Rheumatoid arthritis
  Rheumatoid arthritis is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks synovial joints. The process produces an inflammatory response of the synovium secondary to hyperplasia of synovial cells, excess synovial fluid, and the development...
  
  
• Rheumatoid nodulosis
  Rheumatoid nodulosis
  Rheumatoid nodulosis is a cutaneous condition associated with rheumatoid arthritis, characterized by the appearance of multiple nodules, most often on the hands.- See also :...
  
   (Accelerated rheumatoid nodulosis)
• Rheumatoid vasculitis
  Rheumatoid vasculitis
  Rheumatoid vasculitis is skin condition that is a typical feature of rheumatoid arthritis, presenting as peripheral vascular lesions that are localized purpura, cutaneous ulceration, and gangrene of the distal parts of the extremities.- References :...
  
  
• Rowell's syndrome
  Rowell's syndrome
  Rowell's Syndrome was described by Professor Neville Rowell and colleagues in 1963. Patients with the syndrome have lupus erythematosus , annular skin lesions like erythema multiforme associated with a characteristic pattern of immunological abnormalities. It is uncommon but occurs world wide.-...
  
  
• Scleredema adultorum (Bushke disease, Scleredema diabeticorum, Scleredema adultorum of Buschke, Scleredema of Buschke)
• Silicosis
  Silicosis
  Silicosis, also known as Potter's rot, is a form of occupational lung disease caused by inhalation of crystalline silica dust, and is marked by inflammation and scarring in forms of nodular lesions in the upper lobes of the lungs...
  
  
• Sjögren's syndrome
  Sjögren's syndrome
  Sjögren's syndrome , also known as "Mikulicz disease" and "Sicca syndrome", is a systemic autoimmune disease in which immune cells attack and destroy the exocrine glands that produce tears and saliva....
  
   (Mikulicz disease, Sicca syndrome)
• Subacute cutaneous lupus erythematosus
  Subacute cutaneous lupus erythematosus
  Subacute cutaneous lupus erythematosus is a clinically distinct subset of cases of lupus erythematosus that is most often present in white women aged 15 to 40, consisting of skin lesions that are scaly and evolve as polycyclic annular lesions or psoriasiform plaques.Characteristically the lesions...
  
  
• Systemic lupus erythematosus
  Systemic lupus erythematosus
  Systemic lupus erythematosus , often abbreviated to SLE or lupus, is a systemic autoimmune disease that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage...
  
  
• Toxic oil syndrome
  Toxic oil syndrome
  Toxic Oil Syndrome or simply Toxic Syndrome was the name given to a disease outbreak in Spain in 1981, which killed over 600 people. Its first appearance was as a lung disease, with unusual features: though the symptoms initially resembled a lung infection, antibiotics were ineffective...
  
  
• Tumid lupus erythematosus
  Tumid lupus erythematosus
  Tumid lupus erythematosus is a rare, but distinctive entity in which patients present with edematous erythematous plaques, usually on the trunk....
  
   (Lupus erythematosus tumidus)
• Tuzun syndrome
• Verrucous lupus erythematosus
  Verrucous lupus erythematosus
  Verrucous lupus erythematosus presents with non-puritic papulonodular lesions on the arms and hands, resembling keratoacanthoma or hypertropic lichen planus....
  
   (Hypertrophic lupus erythematosus)
• Winchester syndrome
  Winchester syndrome
  Winchester syndrome in a rare congenital connective tissue disease described in 1969, of which the main characteristics are short stature, marked contractures of joints, opacities in the cornea, a coarse face, dissolution of the carpal and tarsal bones and osteoporosis. Appearances resembled...
  
  

Abnormalities of dermal fibrous and elastic tissue

Abnormalities of dermal fibrous and elastic tissue are caused by problems in the regulation of collagen

Collagen

Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content...

 synthesis and/or degradation.

• Acrodermatitis chronica atrophicans
  Acrodermatitis chronica atrophicans
  Acrodermatitis chronica atrophicans is a skin rash indicative of the third or late stage of European Lyme borreliosis....
  
   (Herxheimer disease, Primary diffuse atrophy)
• Actinic elastosis
  Actinic elastosis
  Actinic, or solar, elastosis is an accumulation of abnormal elastin in the dermis of the skin, and in the conjunctiva of the eye, which occurs as a result of the cumulative effects of prolonged and excessive sun exposure, a process known as photoaging.-Clinical features:Actinic elastosis usually...
  
   (Solar elastosis)
• Anetoderma
  Anetoderma
  Anetoderma is a localized laxity of the skin with herniation or outpouching resulting from abnormal dermal elastic tissue.- See also :...
  
   (Anetoderma maculosa, Anetoderma maculosa cutis, Atrophia maculosa cutis, Macular atrophy)
• Blepharochalasis
  Blepharochalasis
  Blepharochalasis is an inflammation of the eyelid that is characterized by exacerbations and remissions of eyelid edema, which results in a stretching and subsequent atrophy of the eyelid tissue resulting in redundant folds over the lid margins...
  
  
• Cutis laxa
  Cutis laxa
  Cutis laxa is a group of rare connective tissue disorders in which the skin becomes inelastic and hangs loosely in folds.-Causes:In most cases, cutis laxa is inherited...
  
   (Chalazoderma, Dermatochalasia, Dermatolysis, Dermatomegaly, Generalized elastolysis, Generalized elastorrhexis, Pachydermatocele)
• Cutis rhomboidalis nuchae
  Cutis rhomboidalis nuchae
  Cutis rhomboidalis nuchae is a cutaneous condition of the posterior neck, characterized by deep furrowing of the skin....
  
  
• Ehlers–Danlos syndrome (Cutis hyperelastica, Elastic skin, India rubber skin)
• Elastosis perforans serpiginosa
  Elastosis perforans serpiginosa
  Elastosis perforans serpiginosa is a unique perforating disorder characterized by transepidermal elimination of elastic fibers and distinctive clinical lesions, which are serpiginous in distribution and can be associated with specific diseases.- References :...
  
  
• Homocystinuria
  Homocystinuria
  Homocystinuria, also known as cystathionine beta synthase deficiency or CBS deficiency, is an inherited disorder of the metabolism of the amino acid methionine, often involving cystathionine beta synthase...
  
  
• Jadassohn–Pellizzari anetoderma
  Jadassohn–Pellizzari anetoderma
  Jadassohn–Pellizzari anetoderma is a benign condition with focal loss of dermal elastic tissue. Anetoderma comes in three types: Primary anetoderma, secondary anetoderma, and familial anetoderma. Jadassohn-Pellizzari is one of two major classifications of primary anetoderma, the other being...
  
  
• Linear focal elastosis
  Linear focal elastosis
  Linear focal elastosis presents with asymptomatic, palpable or atrophic, yellow lines of the middle and lower back, thighs, arms and breasts....
  
   (Elastotic striae)
• Loeys–Dietz syndrome
• Marfan syndrome
  Marfan syndrome
  Marfan syndrome is a genetic disorder of the connective tissue. People with Marfan's tend to be unusually tall, with long limbs and long, thin fingers....
  
  
• Occipital horn syndrome
  Occipital horn syndrome
  Occipital horn syndrome , formerly considered a variant of Ehlers-Danlos syndrome, is an X-linked recessive connective tissue disorder. It is caused by a deficiency in the transport of the essential mineral copper, associated with mutations in the ATP7A gene...
  
  
• Osteogenesis imperfecta
  Osteogenesis imperfecta
  Osteogenesis imperfecta is a genetic bone disorder. People with OI are born with defective connective tissue, or without the ability to make it, usually because of a deficiency of Type-I collagen...
  
   (Lobstein syndrome)
• Perforating calcific elastosis
  Perforating calcific elastosis
  Perforating calcific elastosis is an acquired, localized cutaneous disorder, most frequently found in obese, multiparous, middle-aged women, characterized by lax, well-circumscribed, reticulated or cobble-stoned...
  
   (Localized acquired cutaneous pseudoxanthoma elasticum, Perforating periumbilical calcific elastosis, Periumbilical perforating pseudoxanthoma elasticum)
• Pseudoxanthoma elasticum
  Pseudoxanthoma elasticum
  Pseudoxanthoma elasticum , also known as Grönblad–Strandberg syndrome, is a genetic disease that causes fragmentation and mineralization of elastic fibers in some tissues. The most common problems arise in the skin and eyes, and later in blood vessels in the form of premature atherosclerosis...
  
   (Grönblad–Strandberg syndrome)
• Reactive perforating collagenosis
  Reactive perforating collagenosis
  Reactive perforating collagenosis is a rare, familial, nonpuritic skin disorder characterized by papules that grow in a diameter of 4 to 6mm and develop a central area of umbilication to which keratinous material is lodged. The etiology of reactive perforating collagenosis is unknown.- References :...
  
  
• Schweninger–Buzzi anetoderma
  Schweninger–Buzzi anetoderma
  Schweninger–Buzzi anetoderma is a cutaneous condition characterized by loss of dermal elastic tissue.- References :...
  
  
• Sclerotic fibroma
  Sclerotic fibroma
  Sclerotic fibromas are a cutaneous condition characterized by well-circumscribed, dome-shaped, dermal hypocellular nodules composed predominantly of sclerotic thick collagen bundles....
  
  
• Striae atrophicans
  Striae atrophicans
  Striae atrophicans are a cutaneous condition characterized by usually multiple, symmetric, well-defined linear atrophic lesions that often follow the lines of cleavage....
  
  
• Striae distensae
  Striae distensae
  Striae distensae are depressed lines or bands of thin reddened skin, which later become white, smooth, shiny, and depressed, occurring in response to changes in weight or muscle mass and skin tension. They are commonly referred to as stretch marks....
  
  
• Ullrich disease
  Ullrich disease
  Ullrich disease is a genetic extracellular matrix diseases of the skin characterized by puffy skin....
  
  
• Verrucous perforating collagenoma
  Verrucous perforating collagenoma
  Verrucous perforating collagenoma is a very rare skin disorder which presents with verrucous papules with a transepidermal elimination of collagen....
  
  
• Wrinkly skin syndrome
  Wrinkly skin syndrome
  Wrinkly skin syndrome is a hereditary connective tissue disorder that is inherited in an autosomal recessive fashion....
  
  

Dermal and subcutaneous growths

Dermal and subcutaneous growths result from (1) reactive or neoplastic proliferation of cellular components of the dermis

Dermis

The dermis is a layer of skin between the epidermis and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis...

 or subcutaneous tissue

Subcutaneous tissue

The hypodermis, also called the hypoderm, subcutaneous tissue, or superficial fascia is the lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages...

, or (2) neoplasms invading or aberrantly present in the dermis.

• Acquired progressive lymphangioma
  Acquired progressive lymphangioma
  Acquired progressive lymphangioma is a group of lymphangiomas that occur anywhere in young individuals, grow slowly, and present as bruise-like lesions or erythematous macules....
  
   (Benign lymphangioendothelioma)
• Acral arteriolar ectasia
  Acral arteriolar ectasia
  Acral arteriolar ectasia is characterized by purple serpiginous ectatic arterioles on the back if the fingers, presenting in the fifth decade of life....
  
  
• Acral fibrokeratoma
  Acral fibrokeratoma
  Acral fibrokeratoma is characterized by a pinkish, hyperkeratotic, hornlike projection occurring on a finger, toe, or palm.- References :...
  
   (Acquired digital fibrokeratoma, Acquired periungual fibrokeratoma)
• Acrochordon
  Acrochordon
  An acrochordon An acrochordon An acrochordon (plural acrochorda, and also known as a (cutaneous) skin tag, or fibroepithelial polyp, is a small benign tumour that forms primarily in areas where the skin forms creases, such as the neck, armpit, and groin. They may also occur on the face, usually on...
  
   (Cutaneous papilloma, Cutaneous tag, Fibroepithelial polyp, Fibroma molluscum, Fibroma pendulum, Papilloma colli, Skin tag, Soft fibroma, Templeton skin tag)
• Adenoma sebaceum
  Adenoma sebaceum
  Adenoma sebaceum is a misnamed cutaneous disorder consisting of angiofibromas that begin in childhood and appear clinically as red papules on the face. Adenoma sebaceum may at times be associated with tuberous sclerosis. Gradually the papules become more prominent with time and persist throughout...
  
  
• Adult type of generalized eruption of cutaneous mastocytosis
• African cutaneous Kaposi sarcoma
  African cutaneous Kaposi sarcoma
  African cutaneous Kaposi sarcoma presents with nodular, infiltrative, vascular masses on the extremities, mostly in men between the ages of 20 and 50, and is endemic in tropical Africa....
  
   
• African lymphadenopathic Kaposi sarcoma
  African lymphadenopathic Kaposi sarcoma
  African lymphadenopathic Kaposi sarcoma is aggressive, occurring in children under 10 years of age, presenting with lymph node involvement, with or without skin lesions....
  
  
• Aggressive infantile fibromatosis
  Aggressive infantile fibromatosis
  Aggressive infantile fibromatosis is a locally recurring, non-metastasizing lesion, presenting with a single or multiple fast-growing masses that are present at birth or occur within the first year of life....
  
  
• AIDS-associated Kaposi sarcoma
  AIDS-associated Kaposi sarcoma
  AIDS-associated Kaposi sarcoma or KS-AIDS presents with cutaneous lesions that begin as one or several red to purple-red macules, rapidly progressing to papules, nodules, and plaques, with a predilection for the head, neck, trunk, and mucous membranes. KS-AIDS simulated the greatest interest as one...
  
  
• Ainhum
  Ainhum
  Ainhum is a painful constriction of the base of the fifth toe frequently followed by bilateral spontaneous amputation a few years later. The disease occurs predominantly in black Africans and their descendants...
  
   (Bankokerend, Dactylolysis spontanea, Sukhapakla)
• Angiofibroma
  Angiofibroma
  Angiofibromas are small, reddish brown or even flesh-colored, smooth, shiny, 0.1- to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks. It contains fibrous tissue....
  
  
• Angiokeratoma
  Angiokeratoma
  Angiokeratoma a is benign cutaneous lesion of capillaries, resulting in small marks of red to blue color and characterized by hyperkeratosis....
  
  
• Angiokeratoma of Mibelli
  Angiokeratoma of Mibelli
  Angiokeratoma of Mibelli consists of 1- to 5-mm red vascular papules, the surfaces of which become hyperkeratotic in the course of time....
  
   (Mibelli's angiokeratoma, Telangiectatic warts)
• Angioleiomyoma
  Angioleiomyoma
  Angioleiomyoma of the skin is thought to arise from vascular smooth muscle, and is generally acquired....
  
   (Vascular leiomyoma)
• Angiolipoleiomyoma
  Angiolipoleiomyoma
  Angiolipoleiomyoma is an acquired, solitary, asymptomatic acral nodule, characterized histologically by well-circumscribed subcutaneous tumors composed of smooth muscle cells, blood vessels, connective tissue, and fat....
  
  
• Angiolipoma
  Angiolipoma
  Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical lipoma. They are commonly painful....
  
  
• Angioma serpiginosum
  Angioma serpiginosum
  Angioma serpiginosum is characterized by minute, copper-colored to bright red angiomatous puncta that have a tendency to become papular....
  
  
• Angiosarcoma
  Angiosarcoma
  Angiosarcoma is a malignant neoplasm of endothelial-type cells that line vessel walls. This may be in reference to blood or lymphatic vessels ....
  
  
• Aponeurotic fibroma
  Aponeurotic fibroma
  Aponeurotic fibroma is characterized by a lesion that usually presents as a painless, solitary, deep fibrous nodule, often adherent to tendon, fascia, or periosteum, on the hands and feet....
  
   (Calcifying aponeurotic fibroma, Juvenile aponeurotic fibroma)
• Atypical fibroxanthoma
  Atypical fibroxanthoma
  Atypical fibroxanthoma of the skin is a low-grade malignancy related to malignant fibrous histiocytoma, which it resembles histologically.-See also:*Skin lesionTumour of skin/soft tissueCommon in the elderlyDifferential diagnoses:...
  
  
• Benign lipoblastomatosis
  Benign lipoblastomatosis
  Benign lipoblastomatosis is a tumor frequently confused with a liposarcoma, affecting exclusively infants and young children, with approximately 90% occurring before 3 years of age....
  
   (Embryonic lipoma)
• Buschke–Ollendorff syndrome (Dermatofibrosis lenticularis disseminata)
• Capillary aneurysms
  Capillary aneurysms
  Capillary aneurysms are flesh colored solitary lesions, resembling an intradermal nevus, which may suddenly grow larger and darker and become blue-black or black as a result of thrombosis....
  
  
• Carcinoid
  Carcinoid
  Carcinoid is a slow-growing type of neuroendocrine tumor, originating in the cells of the neuroendocrine system.In 2000, the World Health Organization redefined "carcinoid", but this new definition has not been accepted by all practitioners. This has led to some complexity in distinguishing...
  
  
• Cherry angioma
  Cherry angioma
  Cherry angiomas, also known as Campbell De Morgan spots or Senile angiomas, are cherry red papules on the skin containing an abnormal proliferation of blood vessels. They are the most common kind of angioma...
  
   (De Morgan spot, Senile angioma)
• Chondrodermatitis nodularis chronica helicis
  Chondrodermatitis nodularis chronica helicis
  Chondrodermatitis nodularis chronica helicis is a small, nodular, tender, chronic inflammatory lesion occurring on the helix of the ear, occurring most often in men....
  
   (Chondrodermatitis nodularis helicis)
• Chondroid lipoma
  Chondroid lipoma
  Chondroid lipomas are deep-seated, firm, yellow tumors that characteristically occur on the legs of women....
  
  
• Chordoma
  Chordoma
  Chordoma is a rare slow-growing malignant neoplasm thought to arise from cellular remnants of the notochord. The evidence for this is the location of the tumors , the similar immunohistochemical staining patterns, and the demonstration that notochordal cells are preferentially left behind in the...
  
  
• Classic Kaposi sarcoma
  Classic Kaposi sarcoma
  Classic Kaposi sarcoma most commonly appears early on the toes and soles as reddish, violaceous, or bluish-black macules and patches that spread and coalesce to form nodules or plaques....
  
  
• Collagenous fibroma
  Collagenous fibroma
  Collagenous fibroma is a slow-growing, deep-set, benign fibrous tumor, usually located in the deep subcutis, fascia, aponeurosis, or skeletal muscle of the extremities, limb girdles, or head and neck regions....
  
   (Desmoplastic fibroblastoma)
• Composite hemangioendothelioma
  Composite hemangioendothelioma
  Composite hemangioendothelioma is a low-grade angiosarcoma typically occurring in adults, although it has been described in infancy....
  
  
• Connective tissue nevus
  Connective tissue nevus
  A connective tissue nevus may be present at birth or appear within the first few years, is elevated, soft to firm, varying from 0.5 to several centimeters in diameter, and may be grouped, linear, or irregularly distributed....
  
   (Collagenoma, Elastoma, Shagreen patch)
• Cutaneous endometriosis
  Cutaneous endometriosis
  Cutaneous endometriosis is characterized by the appearance of brownish papules at the umbilicus or in lower abdominal scars after gynecologic surgery in middle-aged women....
  
  
• Cutaneous meningioma
  Cutaneous meningioma
  Cutaneous meningioma is a developmental defect, and results from the presence of meningocytes outside the calvarium....
  
   (Heterotopic meningeal tissue, Rudimentary meningocele)
• Cutaneous myelofibrosis
  Cutaneous myelofibrosis
  Cutaneous myelofibrosis is a rare skin condition characterized by dermal and subcutaneous nodules....
  
  
• Cutaneous myxoma
  Cutaneous myxoma
  A cutaneous myxoma, AKA superficial angiomyxoma, consists of a multilobulated myxoid mass containing stellate and/or spindled fibroblasts with pools of mucin forming cleft-like spaces. There is often a proliferation of blood vessels and an inflammatory infiltrate...
  
  
• Cutis marmorata telangiectatica congenita
  Cutis marmorata telangiectatica congenita
  Cutis marmorata telangiectatica congenita or CMTC is a rare congenital vascular disorder that usually manifests in affecting the blood vessels of the skin. The condition was first recognised and described in 1922 by Cato van Lohuizen, a Dutch pediatrician whose name was later adopted in the other...
  
   (Congenital generalized phlebectasia, Van Lohuizen syndrome)
• Dermal dendrocyte hamartoma
  Dermal dendrocyte hamartoma
  Dermal dendrocyte hamartoma is characterized by a rounded, medallion-like lesion on the upper trunk in which there is a proliferation of fusiform CD34, factor XIIIa-positive cells in the mid and reticular dermis....
  
  
• Dermatofibroma
  Dermatofibroma
  Benign fibrous histiocytomas are benign skin growths.-Presentation:...
  
   (Benign fibrous histiocytoma, Dermal dendrocytoma, Fibrous dermatofibroma, Fibrous histiocytoma, Fibroma simplex, Histiocytoma, Nodular subepidermal fibrosis, Sclerosing hemangioma)
• Dermatofibrosarcoma protuberans
  Dermatofibrosarcoma protuberans
  Dermatofibrosarcoma protuberans is a very rare tumor. It is a rare neoplasm of the dermis layer of the skin, and is classified as a sarcoma. There is only about 1 case per million per year. DFSP is a fibrosarcoma, more precisely a cutaneous soft tissue sarcoma...
  
  
• Desmoid tumor
  Desmoid tumor
  Aggressive fibromatosis is a rare condition marked by the presence of desmoid tumors, which are benign, slow-growing tumors without any metastatic potential. However, Aggressive Fibromatosis is locally aggressive. Despite their benign nature, they can damage nearby structures causing organ...
  
  
• Diffuse cutaneous mastocytosis
  Diffuse cutaneous mastocytosis
  Diffuse cutaneous mastocytosis has diffuse involvement in which the entire integument may be thickened and infiltrated with mast cells to produce a peculiar orange color, giving rise to the term "homme orange."...
  
  
• Diffuse infantile fibromatosis
  Diffuse infantile fibromatosis
  Diffuse infantile fibromatosis occurs within the first 3 years of life and is usually confined to the muscles of the arms, neck, and shoulder area. There is a multicentric infiltration of muscle fibers with fibroblasts resembling those seen in aponeurotic fibromas....
  
  
• Dupuytren's contracture
  Dupuytren's contracture
  Dupuytren's contracture , is a fixed flexion contracture of the hand where the fingers bend towards the palm and cannot be fully extended...
  
   (Dupuytren's diathesis, Dupuytren's disease, Palmar fibromatosis)
• Eccrine angiomatous hamartoma
  Eccrine angiomatous hamartoma
  Eccrine angiomatous hamartoma usually appear as a solitary nodular lesion on the acral areas of the extremities, particularly the palms and soles....
  
  
• Elastofibroma dorsi
  Elastofibroma dorsi
  Elastofibroma dorsi may be a reparative phenomenon or perhaps a degenerative end-stage response to chronic trauma, presenting as a subcutaneous, tender nodule, up to several centimeters in diameter, typically occurring in women in the sixth to eight decade of life....
  
  
• Endovascular papillary angioendothelioma
  Endovascular papillary angioendothelioma
  Endovascular papillary angioendothelioma is a rare low-grade angiosarcoma that presents as a slow-growing tumor on the head, neck, or extremity of infants or young children....
  
   (Dabska tumor, Dabska-type hemangioendothelioma, Hobnail hemangioendothelioma, Malignant endovascular papillary angioendothelioma, Papillary intralymphatic angioendothelioma)
• Epithelioid hemangioendothelioma
  Epithelioid hemangioendothelioma
  Epithelioid hemangioendothelioma is a rare tumor, first characterized by Sharon Weiss, M.D., that both clinically and histologically is intermediate between angiosarcoma and hemangioma. It is a vascular cancer in the lining of the blood vessels in the liver and lungs so rare that only 0.01 percent...
  
  
• Epithelioid sarcoma
  Epithelioid sarcoma
  Epithelioid sarcoma is a rare mesenchymal soft tissue tumour with an epithelioid pattern. It often occurs in the extremities of young adults.-Diagnosis:...
  
  
• Erythrodermic mastocytosis
  Erythrodermic mastocytosis
  Erythrodermic mastocytosis presents with generalized erythroderma, the skin has a leather-grain appearance, and urtication can be produced over the entire surface....
  
  
• Extraskeletal chondroma
  Extraskeletal chondroma
  Extraskeletal chondroma is a cutaneous condition, a rare benign tumor of mature cartilage....
  
   (Chondroma of soft parts)
• Familial myxovascular fibromas
  Familial myxovascular fibromas
  Familial myxovascular fibromas present with multiple verrucous papules on the palms and fingers, which on biopsy show focal neovascularization and mucin-like changes in the papillary dermis....
  
  
• Fascial hernia
  Fascial hernia
  Fascial hernias in the form of nodules appear in the skin where the deep and superficial veins meet going through the fascia, most frequently occurring on the lower extremities, becoming prominent when the underlying muscles contract....
  
  
• Fibroma of tendon sheath
  Fibroma of tendon sheath
  Fibroma of tendon sheath is a cutaneous condition characterized by a benign tumor that presents as a small subcutaneous nodule that slowly increases in size. These lesions are composed of bland myofibroblasts in a dense fibrous background with cleft-like vessels. The tumor often has a multinodular...
  
  
• Fibromatosis colli
  Fibromatosis colli
  Fibromatosis colli is a benign proliferation of fibrous tissue infiltrating the lower third of the sternocleidomastoid or should region, and is the most common cause of neonatal torticollis....
  
   (Sternomastoid tumor of infancy)
• Fibrous hamartoma of infancy
• Fibrous papule of the nose
  Fibrous papule of the nose
  Fibrous papule of the nose occurs in adults and is characterized by a dome-shaped, sessile, skin-colored, white, or reddish papule 3 to 6mm in diameter on or near the nose....
  
   (Benign solitary fibrous papule, Fibrous papule of the face)
• Folded skin with scarring (Michelin tire baby syndrome)
• Fordyce's spot
  Fordyce's spot
  Fordyce's spots are small, painless, raised, pale, red or white spots or bumps 1 to 3 mm in diameter that may appear on the scrotum, shaft of the penis or on the labia, as well as the inner surface and vermilion border of the lips of the face. They are common in men and women of all ages....
  
   (Angiokeratoma of Fordyce, Angiokeratoma of the scrotum and vulva, Fordyce's disease)
• Ganglion cyst
  Ganglion cyst
  A ganglion cyst, also known as a bible cyst, is a swelling that often appears on or around joints and tendons in the hand or foot. The size of the ganglion or cyst can vary over time. It is most frequently located around the dorsum of the wrist and on the fingers...
  
  
• Ganglioneuroma
  Ganglioneuroma
  Ganglioneuroma is a tumor of the sympathetic nerve fibers arising from neural crest cells.For example, it can be found also in the eye , or in the medulla of adrenal glands. Some may be a progressive form of a neuroblastoma....
  
  
• Genital leiomyoma
  Genital leiomyoma
  Genital leiomyomas are leiomyomas that originate in the dartos muscles of the genitalia, areola, and nipple....
  
   (Dartoic leiomyoma)
• Giant cell fibroblastoma
  Giant cell fibroblastoma
  Giant-cell fibroblastoma is a rare type of soft tissue tumor marked by painless nodules in the dermis and subcutaneous tissue. These tumors may come back after surgery, but they do not spread to other parts of the body...
  
  
• Giant cell tumor of the tendon sheath
  Giant cell tumor of the tendon sheath
  Giant-cell tumor of the tendon sheath, also known as giant-cell synovioma and localized nodular tenosynovitis, is a firm lesion, measuring 1 to 3 cm in diameter, and is most commonly attached to the tendons of the fingers, hands, and wrists, with a predilection for the flexor surfaces...
  
   (Giant cell synovioma, Localized nodular tenosynovitis, Pigmented villonodular synovitis)
• Glomeruloid hemangioma
  Glomeruloid hemangioma
  Glomeruloid hemangioma is a distinctive vascular neoplasm first described in 1990 when found to be associated with Crow-Fukase syndrome and Castleman's disease....
  
   
  
• Glomus tumor
  Glomus tumor
  A glomus tumor is a rare benign neoplasm arising from the glomus body...
  
   (Glomangioma, Solid glomus tumor, Solitary glomus tumor)
• Granular cell tumor
  Granular cell tumor
  Granular cell tumor is a tumor that can develop on any skin or mucosal surface, but occurs on the tongue 40% of the time...
  
   (Abrikossoff's tumor, Abrikossov's tumor, Granular cell myoblastoma, Granular cell nerve sheath tumor, Granular cell schwannoma)
• Hamartoma
  Hamartoma
  A hamartoma is a benign, focal malformation that resembles a neoplasm in the tissue of its origin. This is not a malignant tumor, and it grows at the same rate as the surrounding tissues. It is composed of tissue elements normally found at that site, but which are growing in a disorganized mass...
  
  
• Hemangiopericytoma
  Hemangiopericytoma
  A hemangeopericytoma is a type of soft tissue sarcoma that originates in the pericytes in the walls of capillaries. When inside the nervous system, although not strictly a meningioma tumor, it is a meningeal tumor with an especially aggressive behavior.It was characterized in...
  
  
• Hemangiosarcoma
  Hemangiosarcoma
  Hemangiosarcoma is a rare, rapidly growing, highly invasive variety of cancer. It is a sarcoma arising from the lining of blood vessels; that is, blood-filled channels and spaces are commonly observed microscopically...
  
  
• Hibernoma
  Hibernoma
  A hibernoma is a benign tumour of brown fat, i.e. adipose tissue , and thus a type of lipoma.They arise when brown fat continue to grow.-Histology:...
  
   (Fetal lipoma, Lipoma of embryonic fat, Lipoma of immature adipose tissue)
• Hypertrophic scar
  Hypertrophic scar
  Hypertrophic scars are a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain...
  
  
• Immunosuppression-associated Kaposi sarcoma
  Immunosuppression-associated Kaposi sarcoma
  Immunosuppression-associated Kaposi sarcoma resembles that of classic Kaposi sarcoma; however, the site of presentation is more variable.-References:...
  
  
• Infantile digital fibromatosis
  Infantile digital fibromatosis
  Infantile digital fibromatosis usually occurs as a small, asymptomatic, nodular, dermal fibrous proliferation at the extensor or lateral surface of a finger or toe....
  
   (Inclusion body fibromatosis, Infantile digital myofibroblastoma, Reye tumor)
• Infantile hemangiopericytoma
  Infantile hemangiopericytoma
  Infantile hemangiopericytoma is a cutaneous condition characterized by single or multiple dermal and subcutaneous nodules that may be alarmingly large at birth or grow rapidly....
  
   (Congenital hemangiopericytoma)
• Infantile myofibromatosis
  Infantile myofibromatosis
  Infantile myofibromatosis is the most common fibrous tumor of infancy, in which eighty percent of patients have solitary lesions with half of these occurring on the head and neck, and 60% are present at or soon after birth....
  
   (Congenital generalized fibromatosis, Congenital multicentric fibromatosis)
• Infantile systemic hyalinosis
  Infantile systemic hyalinosis
  Infantile systemic hyalinosis or juvenile systemic hyalinosis is an allelic autosomal-recessive condition characterized by multiple skin nodules, hyaline deposition, gingival hypertrophy, osteolytic bone lesions, and joint contractures.-External links:*...
  
   (Juvenile systemic hyalinosis)
• Intradermal spindle cell lipoma
  Intradermal spindle cell lipoma
  Intradermal spindle cell lipoma is distinct in that it most commonly affects women, and has a wide distribution, occurring with relatively equal frequency on the head and neck, trunk, and upper and lower extremities....
  
  
• Intravascular papillary endothelial hyperplasia
  Intravascular papillary endothelial hyperplasia
  Intravascular papillary endothelial hyperplasia may mimic angiosarcoma, with lesions that are red or purplish 5-mm to 5-cm papules and deep nodules on the head, neck, or upper extremities.-References:...
  
   (Masson's hemangio-endotheliome vegetant intravasculaire, Masson's lesion, Masson's pseudoangiosarcoma, Masson's tumor, Papillary endothelial hyperplasia)
• Juvenile hyaline fibromatosis
  Juvenile hyaline fibromatosis
  Juvenile hyaline fibromatosis is a very rare, autosomal recessive disease due to mutations in capillary morphogenesis protein-2...
  
   (Fibromatosis hyalinica multiplex juvenilis, Murray–Puretic–Drescher syndrome)
• Kaposiform hemangioendothelioma
  Kaposiform hemangioendothelioma
  Kaposiform hemangioendothelioma is an uncommon vascular tumor, first described by Zukerberg, Nickoloff, and Weiss in 1993, that affects infants and young children, with rare cases having also been reported in adults....
  
   (Infantile kaposiform hemangioendothelioma)
• Kasabach–Merritt syndrome (Hemangioma with thrombocytopenia)
• Keloid
  Keloid
  A keloid is a type of scar, which depending on its maturity, is composed mainly of either type III or type I collagen. It is a result of an overgrowth of granulation tissue at the site of a healed skin injury which is then slowly replaced by collagen type 1...
  
   (Keloidal scar)
  
• Keratinizing metaplasia
  Keratinizing metaplasia
  Keratinizing metaplasia is a condition affecting the epithelial surfaces of the body. It is caused by a dietary deficiency of vitamin A, a fat-soluble vitamin that is most often found in fats, milk, and some leafy vegetables....
  
  
• Keratocyst
  Keratocyst
  A keratocyst is a type of cutaneous cyst. They appear similar to epidermoid cysts; however, are not limited to a specified location on the body. Keratocyst are most often reported in persons with nevoid basal cell carcinoma syndrome.-Pathology:...
  
  
• Klippel–Trenaunay syndrome (Angioosteohypertrophy syndrome, Hemangiectatic hypertrophy)
• Knuckle pads
  Knuckle pads
  Knuckle pads are circumscribed, keratotic, fibrous growths over the dorsa of the interphalangeal joints...
  
   (Heloderma)
• Leiomyosarcoma
  Leiomyosarcoma
  Leiomyosarcoma , aka LMS, is a malignant cancer of smooth muscle....
  
  
• Lipoma
  Lipoma
  A lipoma is a benign tumor composed of adipose tissue. It is the most common form of soft tissue tumor. Lipomas are soft to the touch, usually movable, and are generally painless. Many lipomas are small but can enlarge to sizes greater than six centimeters. Lipomas are commonly found in adults...
  
  
• Liposarcoma
  Liposarcoma
  Liposarcoma is a malignant tumor that arises in fat cells in deep soft tissue, such as that inside the thigh or in the retroperitoneum.They are typically large bulky tumors which tend to have multiple smaller satellites extending beyond the main confines of the tumor.Liposarcomas, like all...
  
   (Atypical lipoma, Atypical lipomatous tumor)
• Lymphangiectasis (Lymphangioma)
• Lymphangiomatosis
  Lymphangiomatosis
  Lymphangiomatosis is a condition where a lymphangioma is not present in a single localised mass, but in a widespread or multifocal manner. It is a rare neoplasm which results from an abnormal development of the lymphatic system...
  
  
• Malignant fibrous histiocytoma
  Malignant fibrous histiocytoma
  Pleomorphic undifferentiated sarcoma , also undifferentiated pleomorphic sarcoma and previously malignant fibrous histiocytoma , is a type of soft tissue sarcoma....
  
  
• Malignant peripheral nerve sheath tumor
  Malignant peripheral nerve sheath tumor
  A malignant peripheral nerve sheath tumor is a form of cancer of the connective tissue surrounding nerves. Given its origin and behavior it is classified as a sarcoma...
  
   (Malignant schwannoma, Neurofibrosarcoma, Neurosarcoma)
• Mast cell sarcoma
• Meningocele
• Metastatic carcinoma
  Metastatic carcinoma
  Metastatic carcinoma is able to grow at sites distant from the primary site of origin; thus, dissemination to the skin may occur with any malignant neoplasm, and these infiltrates may result from direct invasion of the skin from underlying tumors, may extend by lymphatic or hematogenous spread, or...
  
  
• Microvenular hemangioma
  Microvenular hemangioma
  Microvenular hemangioma is an acquired benign vascular neoplasm that presents as an asymptomatic, slowly growing, 0.5- to 2.0 cm reddish lesion on the forearms or other sites of young to middle-aged adults....
  
   (Microcapillary hemangioma)
• Midline nevus flammeus
  Midline nevus flammeus
  Midline nevus flammeus is a vascular birthmark which may be found on the glabellar region or on one upper eyelid, and presents in approximately 15% of newborns....
  
   (Angel's kiss, Salmon patch)
• Multifocal lymphangioendotheliomatosis
  Multifocal lymphangioendotheliomatosis
  Multifocal lymphangioendotheliomatosis presents at birth with hundreds of red-brown plaques as large as several centimeters....
  
   (Congenital cutaneovisceral angiomatosis with thrombocytopenia, Multifocal Lymphangioendotheliomatosis with thrombocytopenia)
• Multinucleate cell angiohistocytoma
  Multinucleate cell angiohistocytoma
  Multinucleate cell angiohistocytoma is a cutaneous condition that presents as slowly growing, multiple, discrete but grouped, red to violaceous papules...
  
  
• Multiple cutaneous and uterine leiomyomatosis syndrome
  Multiple cutaneous and uterine leiomyomatosis syndrome
  Multiple cutaneous and uterine leiomyomatosis syndrome is a cutaneous condition caused by mutation in the gene that produces fumarate hydratase....
  
   (Leiomyomatosis cutis et uteri, Multiple leiomyomatosis, Reed's syndrome)
• Multiple cutaneous leiomyoma
  Multiple cutaneous leiomyoma
  Multiple cutaneous leiomyomas arise from the arrectores pilorum muscles, and are made up of a poorly circumscribed proliferation of haphazardly arranged smooth muscle fibers located in the dermis that appear to infiltrate the surrounding tissue and may extend into the subcutis.- See also :*...
  
   (Pilar leiomyoma)
• Neural fibrolipoma
  Neural fibrolipoma
  Neural fibrolipoma is an overgrowth of fibro-fatty tissue along a nerve trunk that often leads to nerve compression....
  
  
• Neuroblastoma
  Neuroblastoma
  Neuroblastoma is the most common extracranial solid cancer in childhood and the most common cancer in infancy, with an annual incidence of about 650 cases per year in the US , and 100 cases per year in the UK . Close to 50 percent of neuroblastoma cases occur in children younger than two years old...
  
   (Infantile neuroblastoma, Neuroepithelioma)
• Neuroma cutis
  Neuroma cutis
  Neuroma cutis is uncommon, with only three true neuromas of the skin and mucous membranes existing: traumatic neuromas, multiple mucosal neuromas, and solitary palisaded encapsulated neuromas....
  
  
• Neurothekeoma
  Neurothekeoma
  Neurothekeoma is a Myxoma and is composed of cords and nests of large cells packed among collagen bundles in close proximity to small nerves....
  
   (Bizarre cutaneous neurofibroma, Cutaneous lobular neuromyxoma, Myxoma of the nerve sheath, Myxomatous perineurioma, Nerve sheath myxoma)
• Nevus flammeus (Capillary malformation, Port-wine stain)
• Nevus flammeus nuchae
  Nevus flammeus nuchae
  Nevus flammeus nuchae, also known as a stork bite, is a congenital capillary malformation present in 25%-50% of newborns. It is a common type of birthmark in a newborn and is usually temporary.-Causes:...
  
   (Stork bite)
• Nevus lipomatosus superficialis
  Nevus lipomatosus superficialis
  Nevus lipomatosus superficialis is characterized by soft, yellowish papules or cerebriform plaques, usually of the buttock or thigh, less often if the ear or scalp, with a wrinkled rather than warty surface....
  
   (Nevus lipomatosis of Hoffman and Zurhelle)
• Nevus oligemicus
  Nevus oligemicus
  Nevus oligemicus presents as a patch of livid skin that is cooler than the normal skin, as a result of decreased blood flow, in which vasoconstriction of deep vessels is thought to be the underlying defect....
  
  
• Nodular fasciitis
  Nodular fasciitis
  Nodular fasciitis, also known as nodular pseudosarcomatous fasciits, pseudosarcomatous fasciitis, and subcutaneous pseudosarcomatous fibromatosis, is a benign soft tissue lesion most commonly found in the superficial fascia. It is most common in young persons on the upper extremities and trunk,...
  
   (Nodular pseudosarcomatous fasciits, Pseudosarcomatous fasciitis, Subcutaneous pseudosarcomatous fibromatosis)
• Oral submucous fibrosis
  Oral submucous fibrosis
  Oral submucous fibrosis is a chronic,complex,irreversible,highly potent pre-cancerous condition characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues . As the disease progresses, the jaws become rigid to the point that the sufferer is unable to...
  
  
• Pachydermodactyly
  Pachydermodactyly
  Pachydermodactyly is a superficial dermal fibromatosis that presents as a poorly circumscribed symmetric, infiltrative, asymptomatic soft-tissue hypertrophy of the proximal fingers, typically sparing the thumbs and fifth fingers and rarely extending proximally to the wrists or occurring distally....
  
  
• Palisaded encapsulated neuroma
  Palisaded encapsulated neuroma
  Palisaded encapsulated neuroma is a cutaneous condition characterized by skin-colored or pink, rubbery, firm papules or nodules....
  
  
• Paraneoplastic syndrome
  Paraneoplastic syndrome
  A paraneoplastic syndrome is a disease or symptom that is the consequence of the presence of cancer in the body, but is not due to the local presence of cancer cells. These phenomena are mediated by humoral factors excreted by tumor cells or by an immune response against the tumor...
  
  
• Pearly penile papules (Hirsuties coronae glandis, Hirsutoid papillomas)
• Peyronie's disease
  Peyronie's disease
  Peyronie's Disease Peyronie's Disease Peyronie's Disease (also known as "Induratio penis plastica", or more recently Chronic Inflammation of the Tunica Albuginea (CITA), is a connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis affecting up to 10% of men...
  
   (Induratio penis plastica)
• Phakomatosis pigmentovascularis
  Phakomatosis pigmentovascularis
  Phakomatosis pigmentovascularis refers to the coexistence of a capillary malformation with various melanocytic lesions, including dermal melanocytosis , nevus spilus, and nevus of Ota....
  
  
• Piloleiomyoma
  Piloleiomyoma
  Piloleiomyomas are a cutaneous condition that present as dermal reddish-brown, pink or skin-colored papules or nodules that can be solitary or multiple....
  
  
• Plantar fibromatosis (Ledderhose's disease)
• Pleomorphic fibroma
  Pleomorphic fibroma
  Pleomorphic fibromas of the skin usually present in adults, with a slight preponderance in women....
  
  
• Pleomorphic lipoma
  Pleomorphic lipoma
  Pleomorphic lipomas, like spindle-cell lipomas, occur for the most part on the backs and necks of elderly men, and are characterized by floret giant cells with overlapping nuclei....
  
  
• Plexiform fibrohistiocytic tumor
  Plexiform fibrohistiocytic tumor
  Plexiform fibrohistiocytic tumor is a rare tumor that arises primarily on the upper extremities of children and young adults....
  
  
• Porokeratotic eccrine ostial and dermal duct nevus
  Porokeratotic eccrine ostial and dermal duct nevus
  Porokeratotic eccrine ostial and dermal duct nevus is a skin lesion that resembles a comedonal nevus, but it occurs on the palms and soles where pilosebaceous follicles are normally absent. It is probably transmitted by paradominant transmission....
  
  
• Progressive nodular histiocytoma
  Progressive nodular histiocytoma
  Progressive nodular histiocytoma is a cutaneous condition characterized by generalized, discrete yellow papules and nodules with prominent facial involvement....
  
  
• Proliferating angioendotheliomatosis
  Proliferating angioendotheliomatosis
  Proliferating angioendotheliomatosis has historically been divided into two groups, a reactive, involuting type and a malignant, rapidly fatal type....
  
  
• Prominent inferior labial artery
  Prominent inferior labial artery
  Prominent inferior labial artery is characterized by the appearance of a pulsating papule in the lower vermilion, a centimeter of two from the oral comissure, formed by an especially tortuous segment of the inferior labial artery....
  
  
• Pseudo-ainhum
  Pseudo-ainhum
  Pseudo-ainhum has been a term used in connection with certain hereditary and nonhereditary diseases in which annular constriction of digits occur, and treatment may be with surgery or intralesional injections of corticosteroids, as in ainhum. It is rarely seen in the United States but often...
  
  
• Retiform hemangioendothelioma
  Retiform hemangioendothelioma
  Retiform hemangioendothelioma is a low-grade angiosarcoma, first described in 1994, presenting as a slow-growing exophytic mass, dermal plaque, or subcutaneous nodule....
  
   (Hobnail hemangioendothelioma)
• Schwannoma
  Schwannoma
  A schwannoma is a benign nerve sheath tumor composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves....
  
   (Acoustic neuroma, Neurilemmoma, Neurinoma, Neurolemmoma, Schwann cell tumor)
• Solitary angiokeratoma
  Solitary angiokeratoma
  Solitary angiokeratoma is a small, bluish-black, warty papule that occurs predominantly on the lower extremities....
  
  
• Solitary cutaneous leiomyoma
  Solitary cutaneous leiomyoma
  Solitary cutaneous leiomyoma typically presents as a deeply circumscribed, freely movable, rounded nodule ranging from 2 to 15mm in diameter, with overlying skin that may have a reddish or violaceous tint....
  
  
• Solitary mastocytoma
  Solitary mastocytoma
  Solitary mastocytoma may be present at birth or may develop during the first weeks of life, originating as a brown macule that urticates on stroking....
  
   
  
• Solitary neurofibroma
  Solitary neurofibroma
  A solitary neurofibroma may be 2 to 20mm in diameter, is soft, flaccid, and pinkish-white, and frequently this soft small tumor can be invaginated, as if through a ring in the skin by pressure with the finger, a maneuver called "button-holing."...
  
   (Plexiform neurofibroma, Solitary nerve sheath tumor, Sporadic neurofibroma)
• Spider angioma
  Spider angioma
  A spider angioma is a type of telangiectasis found slightly beneath the skin surface, often containing a central red spot and reddish extensions which radiate outwards like a spider's web...
  
   (Nevus araneus, Spider telangiectasia, Spider nevus, Vascular spider)
• Spindle cell hemangioendothelioma (Spindle cell hemangioma)
• Spindle cell lipoma
• Sternal cleft
  Sternal cleft
  Sternal clefts are rare congenital malformations that result from defective embryologic fusion of paired mesodermal bands in the ventral midline.- References :...
  
  
• Subungual exostosis
• Superficial acral fibromyxoma
  Superficial acral fibromyxoma
  A superficial acral fibromyxoma is a type of Myxoma and is a rare cutaneous condition characterized by a mesenchymal neoplasm that typically occurs on the digits of middle-age adults....
  
  
• Systemic mastocytosis
• Targetoid hemosiderotic hemangioma
  Targetoid hemosiderotic hemangioma
  Targetoid hemosiderotic hemangioma is a cutaneous condition characterized by a central brown or violaceous papule that is surrounded by an ecchymotic halo....
  
   (Hobnail hemangioma)
• Telangiectasia
  Telangiectasia
  Telangiectasias /tɛ.læn.dʒiː'ɛk.teɪ.ʃi:ə/ are small dilated blood vessels near the surface of the skin or mucous membranes, measuring between 0.5 and 1 millimeter in diameter. They can develop anywhere on the body but are commonly seen on the face around the nose, cheeks, and chin...
  
  
• Telangiectasia macularis eruptiva perstans
  Telangiectasia macularis eruptiva perstans
  Telangiectasia macularis eruptiva perstans is persistent, pigmented, asymptomatic eruption of macules usually less than 0.5cm in diameter with a slightly reddish-brown tinge.-References:...
  
  
• Teratoma
  Teratoma
  A teratoma is an encapsulated tumor with tissue or organ components resembling normal derivatives of all three germ layers. There are rare occasions when not all three germ layers are identifiable...
  
  
• Tufted angioma
  Tufted angioma
  A tufted angioma usually develops in infancy or early childhood on the neck and upper trunk, and is an ill-defined, dull red macule with a mottled appearance, varying from 2 to 5 cm in diameter....
  
   (Acquired tufted angioma, Angioblastoma, Angioblastoma of Nakagawa, Hypertrophic hemangioma, Progressive capillary hemangioma, Tufted hemangioma)
• Umbilical granuloma
  Umbilical granuloma
  Umbilical granuloma is the most common umbilical abnormality in neonates, causing inflammation and drainage....
  
  
• Universal angiomatosis
  Universal angiomatosis
  Universal angiomatosis is a bleeding disease that affects the blood vessels of the skin and mucous membranes as well as other parts of the body....
  
   (Generalized telangiectasia)
• Urticaria pigmentosa
  Urticaria pigmentosa
  Urticaria pigmentosa is the most common form of cutaneous mastocytosis...
  
   (Childhood type of generalized eruption of cutaneous mastocytosis)
• Venous lake
  Venous lake
  A venous lake is an asymptomatic, generally solitary, soft, compressible, dark blue to violaceous, 0.2- to 1-cm papule commonly found on sun-exposed surfaces of the vermilion border of the lip, face and ears...
  
   (Phlebectases)
• Wildervanck syndrome
  Wildervanck syndrome
  Wildervanck syndrome is a developmental disorder that may be characterized by accessory tragi.- See also :* WHIM syndrome* List of cutaneous conditions* Xanthelasmoidal mastocytosis...
  
  
• Xanthelasmoidal mastocytosis
  Xanthelasmoidal mastocytosis
  Xanthelasmoidal mastocytosis is a cutaneous condition characterized by numerous, confluent, yellow–tan papules....
  
  
• Zosteriform metastasis
  Zosteriform metastasis
  Zosteriform metastasis is when visceral carcinomas spread to the skin in dermatomal crops of succulent nodules....
  
  

Dermatitis

Dermatitis

Dermatitis

-Etymology:Dermatitis derives from Greek derma "skin" + -itis "inflammation" and genetic disorder.-Terminology:There are several different types of dermatitis. The different kinds usually have in common an allergic reaction to specific allergens. The term may describe eczema, which is also called...

 is a general term for "inflammation

Inflammation

Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...

 of the skin."

• Essential dermatitis
  Essential dermatitis
  Essential dermatitis is an idiopathic inflammation of the skin that does not fit the picture of other well defined conditions and is a diagnosis of exclusion....
  
  

Atopic

Atopic dermatitis

Atopic dermatitis

Atopic dermatitis is an inflammatory, chronically relapsing, non-contagious and pruritic skin disorder...

 is a chronic

Chronic (medicine)

A chronic disease is a disease or other human health condition that is persistent or long-lasting in nature. The term chronic is usually applied when the course of the disease lasts for more than three months. Common chronic diseases include asthma, cancer, diabetes and HIV/AIDS.In medicine, the...

 dermatitis

Dermatitis

-Etymology:Dermatitis derives from Greek derma "skin" + -itis "inflammation" and genetic disorder.-Terminology:There are several different types of dermatitis. The different kinds usually have in common an allergic reaction to specific allergens. The term may describe eczema, which is also called...

 associated with a hereditary tendency to develop allergies

Allergy

An Allergy is a hypersensitivity disorder of the immune system. Allergic reactions occur when a person's immune system reacts to normally harmless substances in the environment. A substance that causes a reaction is called an allergen. These reactions are acquired, predictable, and rapid...

 to food and inhalant substances.

• Atopic dermatitis
  Atopic dermatitis
  Atopic dermatitis is an inflammatory, chronically relapsing, non-contagious and pruritic skin disorder...
  
   (Atopic eczema, Disseminated neurodermatitis, Flexural eczema, Infantile eczema, Prurigo diathsique)

Contact

Contact dermatitis

Contact dermatitis

Contact dermatitis is a term for a skin reaction resulting from exposure to allergens or irritants . Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight....

 is caused by certain substances coming in contact with the skin.

• Abietic acid dermatitis
  Abietic acid dermatitis
  Abietic acid dermatitis is a contact dermatitis often seen in association with musical instruments.-Causes:The main cause is a a type-I hypersensitivity reaction to products containing abietic acid, such as the rosin/colophony, which is commonly used as a friction-increasing agent...
  
  
• Acid-induced
• Acrylic monomer dermatitis
• Adhesive dermatitis
• African blackwood dermatitis
  African blackwood dermatitis
  African blackwood dermatitis is a condition characterized by an allergic contact dermatitis associated with a musical instrument made of a particular type of wood....
  
  
• Airbag dermatitis
  Airbag dermatitis
  Airbag dermatitis is caused skin irritation and trauma secondary to the deployment of airbags....
  
   (Airbag burn)
• Alkali-induced
• Allergic
  Allergic contact dermatitis
  Allergic contact dermatitis is a form of contact dermatitis that is the manifestation of an allergic response caused by contact with a substance....
  
  
• Antifungal agent-induced
• Antimicrobial agent-induced
• Arsenic dermatitis
• Artificial nail-induced
• Axillary antiperspirant-induced
• Axillary deodorant-induced
• Baboon syndrome
  Baboon syndrome
  Baboon syndrome is systemic contact dermatitis characterized by well-demarcated patches of erythema distributed symmetrically on the buttock....
  
  
• Black dermatographism
• Bleaching cream-induced
• Capsaisin-induced
• Chemical burn
  Chemical burn
  A chemical burn occurs when living tissue is exposed to a corrosive substance such as a strong acid or base. Chemical burns follow standard burn classification and may cause extensive tissue damage. The main types of irritant and/or corrosive products are: acids, bases, oxidizers, solvents,...
  
   
  
• Chloracne
  Chloracne
  Chloracne is an acne-like eruption of blackheads, cysts, and pustules associated with over-exposure to certain halogenated aromatic compounds, such as chlorinated dioxins and dibenzofurans...
  
  
• Chrome dermatitis
• Clothing-induced
• Cobalt dermatitis
• Contact stomatitis
  Contact stomatitis
  Contact stomatitis is characterized by cutaneous lesions that may be located where the offending agent contacts the mucosa for a prolonged time....
  
   (Contact lichenoid reaction, Lichenoid amalgam reaction, Oral mucosal cinnamon reaction)
• Contact urticaria
• Corticosteroid-induced
• Cosmetic dermatitis
• Cosmetic intolerance syndrome
• Dentifrice-induced
• Dermatitis from metals and metal salts
• Dust-induced
• Epoxy resin dermatitis
• Ethylenediamine-induced
• Eye makeup-induced
• Fiberglass dermatitis
• Flower-induced
• Formaldehyde-induced
• Formaldehyde-releasing agent-induced
• Fragrance-induced
• Gold dermatitis
• Hair bleach-induced
• Hair dye-induced
• Hair lotion-induced
• Hair spray-induced
• Hair straightener-induced
• Hair tonic-induced
• Houseplant-induced
• Hydrocarbon-induced
• Irritant folliculitis
  Irritant folliculitis
  Irritant folliculitis is a cutaneous condition and usually occurs following the application of topical medications ....
  
  
• Lacquer dermatitis
  Lacquer dermatitis
  Lacquer dermatitis is a cutaneous condition characterized by a contact dermatitis to various lacquers....
  
   (Lacquer sensitivity)
• Lanolin-induced
• Lipstick-induced
• Local anesthetic-induced
• Makassar ebony dermatitis
• Marine plant-induced
• Mechanical irritant dermatitis
• Mercury dermatitis
• Mouthwash-induced
• Nail lacquer-induced
• Nail polish remover-induced
• Nickel dermatitis
• Occupation-induced
• p-Chloro-Meta-Xylenol-induced
• Paraben-induced
• Paraphenylenediamine dermatitis
• Permanent wave preparation-induced
• Phenothiazine drug-induced
• Photoallergic
• Photoirritant
• Plant derivative-induced
• Pollen-induced
• Polyester resin dermatitis
• Propylene glycol-induced 
  
• Protein contact dermatitis
  Protein contact dermatitis
  Protein contact dermatitis is a cutaneous condition, and was a term originally used to describe an eczematous reaction to protein-containing material in food handlers....
  
  
• Quaternium-15 hypersensitivity
• Reed dermatitis
• Rosewood dermatitis
• Rosin dermatitis
• Rubber dermatitis
• Seed-induced
• Shoe dermatitis
• Solvent-induced
• Sorbic acid-induced
• Subjective irritant contact dermatitis (Sensory irritant contact dermatitis)
• Sunscreen-induced
• Systemic contact dermatitis
• Tear gas dermatitis
• Textile dermatitis
• Toxicodendron dermatitis (Poison ivy)
• Traumatic irritant contact dermatitis
• Tree-associated plant-induced
• Tree-induced
• Tulip fingers
  Tulip fingers
  Tulip fingers are a cutaneous condition, a combined allergic and irritant contact dermatitis caused by contact with tulip bulbs....
  
  
• Vegetable-induced

Eczema

Eczema

Eczema

Eczema is a form of dermatitis, or inflammation of the epidermis . In England, an estimated 5.7 million or about one in every nine people have been diagnosed with the disease by a clinician at some point in their lives.The term eczema is broadly applied to a range of persistent skin conditions...

 refers to a broad range of conditions that begin as spongiotic

Spongiosis

Spongiosis is mainly intercellular edema between the keratinocytes in the epidermis, and is characteristic of eczematous dermatitis, manifested clinically by vesicles, "juicy" papules, and/or lichenification....

 dermatitis

Dermatitis

-Etymology:Dermatitis derives from Greek derma "skin" + -itis "inflammation" and genetic disorder.-Terminology:There are several different types of dermatitis. The different kinds usually have in common an allergic reaction to specific allergens. The term may describe eczema, which is also called...

 and may progress to a lichenified stage.

• Autoimmune estrogen dermatitis
  Autoimmune estrogen dermatitis
  Autoimmune estrogen dermatitis presents as a cyclic skin disorder that may appear eczematous, papular, bullous, or urticarial. with pruritus typically present, skin eruptions that may be chronic but which are exacerbated premenstrually or occur immediately following menses....
  
  
• Autoimmune progesterone dermatitis
  Autoimmune progesterone dermatitis
  Autoimmune progesterone dermatitis may appear as urticarial papules, deep gyrate lesions, papulovesicular lesions, an eczematous eruption, or as targetoid lesions. Autoimmune progesterone dermatitis initially manifests with eye symptoms, e.g. burning, and progresses into rashes...
  
  
• Autosensitization dermatitis
  Autosensitization dermatitis
  Autosensitization dermatitis presents with the development of widespread dermatitis or dermatitis distant from a local inflammatory focus, a process referred to as autoeczematization....
  
  
• Breast eczema
  Breast eczema
  Breast eczema may affect the nipples, areolae, or surrounding skin, with eczema of the nipples being of the moist type with oozing and crusting, in which painful fissuring is frequently seen, especially in nursing mothers....
  
   (Nipple eczema)
• Chronic vesiculobullous hand eczema
  Chronic vesiculobullous hand eczema
  Chronic vesiculobullous hand eczema presents with lesions that may be hyperkeratotic, scaling, and fissures, and the "dyshidrosiform" pattern may be recognized only during exacerbations. Females outnumber names by 3:1, and there is a tendency for the pruritic 1- to 2-mm vesicles to be most...
  
  
• Circumostomy eczema
  Circumostomy eczema
  Circumostomy eczema frequently occurs after an ileostomy or colostomy in which there is eczematization or autosensitization of the surrounding skin....
  
  
• Dyshidrosis
  Dyshidrosis
  Dyshidrosis is a skin condition that is characterized by small blisters on the hands or feet...
  
   (Acute vesiculobullous hand eczema, Cheiropompholyx, Dyshidrotic eczema, Pompholyx, Podopompholyx)
• Ear eczema
  Ear eczema
  Ear eczema may involve the helix, postauricular fold, and external auditory canal, with the most frequently affected site being the external canal, where it is often a manifestation of seborrheic dermatitis or allergic contact dermatitis....
  
  
• Eyelid dermatitis
  Eyelid dermatitis
  Eyelid dermatitis is commonly related to atopic dermatitis or allergic contact dermatitis. Volatile substances, tosylamide, epoxy hardeners, insect sprays, and lemon peel oil may be implicated, with many cases of eyelid contact dermatitis being caused by substances transferred by the hands to the...
  
  
• Hand eczema
  Hand eczema
  Hand eczema presents on the palms and soles, and may sometimes be difficult or impossible to differentiate from atopic dermatitis, allergic contact dermatitis, and psoriasis, which also commonly involve the hands...
  
  
• Hyperkeratotic hand dermatitis
  Hyperkeratotic hand dermatitis
  Hyperkeratotic hand dermatitis presents with hyperkeratotic, fissure-prone, erythematous areas of the middle or proximal palm, and the volar surfaces of the fingers may also be involved....
  
  
• Id reaction
  Id reaction
  Id reactions present with a variety of infectious disorders, often occurring in response to an inflammatory tinea of the feet, resulting in an eczematous dermatitis....
  
   (Disseminated eczema, Generalized eczema)
• Irritant diaper dermatitis (Diaper dermatitis, Napkin dermatitis)
• Juvenile plantar dermatosis
  Juvenile plantar dermatosis
  Juvenile plantar dermatosis is a condition usually seen in children between the ages of 3 and 14, and involves the cracking and peeling of weight bearing areas of the soles of the feet.- References :...
  
   (Atopic winter feet, Dermatitis plantaris sicca, Forefoot dermatitis, Moon-boot foot syndrome, Sweaty sock dermatitis)
• Molluscum dermatitis
  Molluscum dermatitis
  Molluscum dermatitis represents a unique form of id reaction, in which patients may present with localized or widespread eczema surrounding scattered lesions of molluscum contagiosum....
  
  
• Nummular dermatitis
  Nummular dermatitis
  Nummular dermatitis is one of the many forms of dermatitis. Also known as discoid dermatitis, it is characterized by round or oval-shaped itchy lesions...
  
   (Discoid eczema, Microbial eczema, Nummular eczema, Nummular neurodermatitis)
• Nutritional deficiency eczema
  Nutritional deficiency eczema
  Nutritional deficiency eczema is a pattern of eczema with localized, thickened, scaling patches that have some characteristics of nummular eczema, seborrheic dermatitis, and neurodermatitis that may be seen in alcoholics....
  
  
• Sulzberger–Garbe syndrome
  Sulzberger–Garbe syndrome
  Sulzberger–Garbe syndrome is a cutaneous condition, a type of therapy resistant nummular eczema....
  
   (Oid-oid disease)
• Xerotic eczema
  Xerotic eczema
  Xerotic eczema is a form of eczema that is characterized by changes that occur when skin becomes abnormally dry, itchy, and cracked...
  
   (Asteatotic eczema, Desiccation dermatitis, Eczema craquelé, Pruritus hiemalis, Winter eczema, Winter itch)

Pustular

Pustular dermatitis is an inflammation

Inflammation

Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...

 of the skin that presents with pus

Pus

Pus is a viscous exudate, typically whitish-yellow, yellow, or yellow-brown, formed at the site of inflammatory during infection. An accumulation of pus in an enclosed tissue space is known as an abscess, whereas a visible collection of pus within or beneath the epidermis is known as a pustule or...

tular lesions.

• Eosinophilic pustular folliculitis (Ofuji's disease, Sterile eosinophilic pustulosis)
• Reactive arthritis
  Reactive arthritis
  Reactive arthritis , is classified as an autoimmune condition that develops in response to an infection in another part of the body. Coming into contact with bacteria and developing an infection can trigger the disease. Reiter's syndrome has symptoms similar to various other conditions collectively...
  
   (Reiter's disease, Reiter's syndrome)
• Subcorneal pustular dermatosis
  Subcorneal pustular dermatosis
  Subcorneal pustular dermatosis is skin condition that is a rare, chronic, recurrent, pustular eruption characterized histopathologically by subcorneal pustules that contain abundant neutrophils....
  
   (Sneddon–Wilkinson disease)

Seborrheic

Seborrheic dermatitis is a chronic

Chronic (medicine)

A chronic disease is a disease or other human health condition that is persistent or long-lasting in nature. The term chronic is usually applied when the course of the disease lasts for more than three months. Common chronic diseases include asthma, cancer, diabetes and HIV/AIDS.In medicine, the...

, superficial, inflammatory

Inflammation

Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...

 disease characterized by scaling on an erythema

Erythema

Erythema is redness of the skin, caused by hyperemia of the capillaries in the lower layers of the skin. It occurs with any skin injury, infection, or inflammation...

tous base.

• Infantile seborrheic dermatitis
• Leiner's disease
  Leiner's disease
  Leiner's disease is a systemic disease, a skin disorder and extends to erythroma, typically diagnosed in early infancy. Leiner’s disease is characterized by a long lasting seborrhea dermatitis associated with increased likelihood to infection...
  
  
• Pityriasis simplex capillitii (Dandruff)
• Seborrheic dermatitis (Seborrheic eczema)

Disturbances of pigmentation

Disturbances of human pigmentation, either loss or reduction, may be related to loss of melanocyte

Melanocyte

-External links: - "Eye: fovea, RPE" - "Integument: pigmented skin"...

s or the inability of melanocytes to produce melanin

Melanin

Melanin is a pigment that is ubiquitous in nature, being found in most organisms . In animals melanin pigments are derivatives of the amino acid tyrosine. The most common form of biological melanin is eumelanin, a brown-black polymer of dihydroxyindole carboxylic acids, and their reduced forms...

 or transport melanosome

Melanosome

In a biological cell, a melanosome is an organelle containing melanin, the most common light-absorbing pigment found in the animal kingdom.Cells that synthesize melanins are called melanocytes, and also the retinal pigment epithelium cells, whereas cells that have merely engulfed the melanosomes...

s correctly.

• Albinism–black lock–cell migration disorder of the neurocytes of the gut–deafness syndrome (ABCD syndrome)
• Albinism–deafness syndrome
  Albinism–deafness syndrome
  Albinism–deafness syndrome is a condition characterized by congenital neural deafness and a severe or extreme piebald-like phenotype with extensive areas of hypopigmentation....
  
   (Woolf syndrome, Ziprkowski–Margolis syndrome)
• Alezzandrini syndrome
  Alezzandrini syndrome
  Alezzandrini syndrome is a very rare syndrome characterized by a unilateral degenerative retinitis, followed after several months by ipsilateral vitiligo on the face and ipsilateral poliosis. Deafness may also be present....
  
  
• Argyria
  Argyria
  Argyria is a condition caused by improper exposure to chemical forms of the element silver, silver dust, or silver compounds. The most dramatic symptom of argyria is that the skin becomes blue or bluish-grey colored. Argyria may be found as generalized argyria or local argyria...
  
  
• Arsenic poisoning
  Arsenic poisoning
  Arsenic poisoning is a medical condition caused by increased levels of the element arsenic in the body. Arsenic interferes with cellular longevity by allosteric inhibition of an essential metabolic enzyme...
  
   
• Berlin syndrome
• Canthaxanthin
  Canthaxanthin
  Canthaxanthin is a carotenoid pigment widely distributed in nature. Carotenoids belong to a larger class of phytochemicals known as terpenoids. The chemical formula of canthaxanthin is C40H52O2. It has E number E161g and is approved for use in the EU and USA however it is not approved for usage in...
  
  
• Chédiak–Higashi syndrome
• Chrysiasis
  Chrysiasis
  Chrysiasis is a dermatological condition induced by the parenteral administration of gold salts, usually for the treatment of rheumatoid arthritis...
  
  
• Cross–McKusick–Breen syndrome (Cross syndrome, Oculocerebral-hypopigmentation syndrome)
• Dermatopathia pigmentosa reticularis
  Dermatopathia pigmentosa reticularis
  Dermatopathia pigmentosa reticularis is a rare, autosomal dominant congenital disorder that is a form of ectodermal dysplasia...
  
   (Dermatopathia pigmentosa reticularis hyperkeratotica et mutilans, Dermatopathia pigmentosa reticularis hypohidotica et atrophica, Dermatopathic pigmentosa reticularis)
• Dyschromatosis symmetrica hereditaria
  Dyschromatosis symmetrica hereditaria
  Dyschromatosis symmetrica hereditaria presents primarily in the Japanese, but has also been found to affect individuals from Europe, India, and the Caribbean, characterized by progressively pigmented and depigmented macules, often mixed in a reticulate pattern, concentrated on the...
  
   (Reticulate acropigmentation of Dohi, Symmetrical dyschromatosis of the extremities)
• Dyschromatosis universalis hereditaria
• Elejalde syndrome
  Elejalde syndrome
  Elejalde syndrome is a rare autosomal recessive syndrome consisting of moderate pigment dilution, profound primary neurologic defects, no immune defects, and hair with metallic silvery sheen....
  
   (Griscelli syndrome type 1)
• Familial progressive hyperpigmentation
  Familial progressive hyperpigmentation
  Familial progressive hyperpigmentation is characterized by patches of hyperpigmentation, present at birth, which increase in size and number with age. This is a genetic disease, however the gene that accounts for this spotty darkening of the skin has yet to be discovered. Although rare, the...
  
  
• Galli–Galli disease
• Griscelli syndrome type 2
  Griscelli syndrome type 2
  Griscelli syndrome type 2 is a rare autosomal recessive syndrome characterized by variable pigmentary dilution, hair with silvery metallic sheen, frequent pyogenic infections, neutropenia, and thrombocytopenia.-References:...
  
   (Partial albinism with immunodeficiency)
• Griscelli syndrome type 3
  Griscelli syndrome type 3
  Griscelli syndrome type 3 is a disorder of melanosome transport presenting initially with hypopigmentation....
  
  
• Hemochromatosis (Bronze diabetes)
• Hemosiderin hyperpigmentation
  Hemosiderin hyperpigmentation
  Hemosiderin hyperpigmentation is pigmentation due to deposits of hemosiderin, and occurs in purpura, hemochromotosis, hemorrhagic diseases, and stasis dermatitis....
  
  
• Hermansky–Pudlak syndrome
• Idiopathic guttate hypomelanosis
  Idiopathic guttate hypomelanosis
  Idiopathic guttate hypomelanosis is a very common acquired disorder that affects women more frequently than men, presenting with skin lesions that occur chiefly on the skins and forearms, suggesting sun exposure may play a role....
  
   (Leukopathia symmetrica progressiva)
• Iron metallic discoloration
  Iron metallic discoloration
  Iron metallic discoloration occurred more frequently in the past when soluble iron compounds were used in the treatment of allergic contact and other dermatitis, and in eroded areas iron was sometimes deposited in the skin, like a tattoo ....
  
  
• Klein–Waardenburg syndrome
• Lead poisoning
  Lead poisoning
  Lead poisoning is a medical condition caused by increased levels of the heavy metal lead in the body. Lead interferes with a variety of body processes and is toxic to many organs and tissues including the heart, bones, intestines, kidneys, and reproductive and nervous systems...
  
  
• Leukoderma
  Leukoderma
  Leukoderma is a cutaneous condition, an acquired condition with localized loss of pigmentation of the skin that may occur after any number of inflammatory skin conditions, burns, intralesional steroid injections, postdermabrasion, etc....
  
  
• Melanoma-associated leukoderma
  Melanoma-associated leukoderma
  Melanoma-associated leukoderma is a cutaneous condition, and is a vitiligo-like depigmentation that can occur in patients with cutaneous or ocular melanoma....
  
  
• Melasma
  Melasma
  Melasma is a tan or dark skin discoloration. Although it can affect anyone, melasma is particularly common in women, especially pregnant women and those who are taking oral or patch contraceptives or hormone replacement therapy medications...
  
   (Chloasma faciei, Mask of pregnancy)
• Mukamel syndrome
  Mukamel syndrome
  Mukamel syndrome is a cutaneous condition characterized by premature graying, lentigines, depigmented macules, microcephaly, and scoliosis....
  
  
• Necklace of Venus
  Necklace of Venus
  Necklace of Venus is a cutaneous condition characterized by a background hyperpigmentation with superimposed white macules on neck....
  
  
• Nevus anemicus
  Nevus anemicus
  Nevus anemicus is a congenital disorder characterized by macules of varying size and shape that are paler than the surrounding skin and cannot be made red by trauma, cold, or heat...
  
  
• Nevus depigmentosus
  Nevus depigmentosus
  Nevus depigmentosus or nevus achromicus is a depigmentation problem in skin which can be easily differentiated from vitiligo. Although age factor has not much involvement in the nevus depigmentosus but in about 19% of the cases these are noted at birth. Their size may however grow in proportion to...
  
   (Nevus achromicus)
• Ocular albinism
  Ocular albinism
  Ocular albinism is a form of albinism which, in contrast to oculocutaneous albinism, presents primarily in the eyes. There are multiple forms of ocular albinism, which are clinically similar.Both known genes are on the X chromosome...
  
  
• Oculocutaneous albinism
  Oculocutaneous albinism
  Oculocutaneous albinism is a form of albinism involving the eyes , skin , and in rare instances, the hair as well.Four types of oculocutaneous albinism have been described, all caused by a disruption of melanin synthesis and all autosomal recessive disorders.Common Albinism requires genes from both...
  
  
• Pallister–Killian syndrome
• Periorbital hyperpigmentation
  Periorbital hyperpigmentation
  Periorbital hyperpigmentation is characterized by dark circles around the eyes, which are common, often familial, and frequently found in individuals with dark pigmentation or Mediterranean ancestry. Atopic patients may also exhibit periorbital pigmentation , and treatment is ineffective....
  
  
• Photoleukomelanodermatitis of Kobori
  Photoleukomelanodermatitis of Kobori
  Photoleukomelanodermatitis of Kobori is a cutaneous condition, a dyschromic drug eruption that occurs after ingestion of afloqualone, thiazides or tetracyclines, followed by exposure to sunlight.- See also :...
  
  
• Phylloid hypomelanosis
  Phylloid hypomelanosis
  Phylloid hypomelanosis is a cutaneous condition, a syndrome occurring in patients with mosaic trisomy 13 or translocation trisomy 13....
  
  
• Piebaldism
  Piebaldism
  Piebaldism is a rare autosomal dominant disorder of melanocyte development. Common characteristics include a congenital white forelock, scattered normal pigmented and hypopigmented macules and a triangular shaped depigmented patch on the forehead....
  
  
• Pigmentatio reticularis faciei et colli
  Pigmentatio reticularis faciei et colli
  Pigmentatio reticularis faciei et colli is a cutaneous condition characterized by a disturbance of human pigmentation.- See also :* Erythromelanosis follicularis faciei et colli* List of cutaneous conditions...
  
  
• Pityriasis alba
  Pityriasis alba
  Pityriasis alba is a common skin condition mostly occurring in children and usually seen as dry, fine-scaled, pale patches on the face. It is self-limiting and usually only requires use of moisturizer creams....
  
  
• Poikiloderma of Civatte
  Poikiloderma of Civatte
  Poikiloderma of Civatte is a cutaneous condition and refers to reticulated red to red-brown patches with telangiectasias.- See also :* Poikiloderma vasculare atrophicans* Cutis rhomboidalis nuchae* List of cutaneous conditions* Poikiloderma...
  
  
• Poikiloderma vasculare atrophicans
  Poikiloderma vasculare atrophicans
  Poikiloderma vasculare atrophicans , sometimes referred to as parapsoriasis variegata or parapsoriasis lichenoides is a cutaneous condition characterized by hypo- or hyperpigmentation , telangiectasia and skin atrophy...
  
  
• Postinflammatory hyperpigmentation
  Postinflammatory hyperpigmentation
  Postinflammatory hyperpigmentation can result from any natural or iatrogenic inflammatory condition, resulting from two mechanism: increased epidermal pigmentation via increased melanocyte activity or dermal melanosis from melanocyte damage and melanin drop out from the epidermis into the dermis....
  
   (Postinflammatory hypermelanosis)
• Postinflammatory hypopigmentation
  Postinflammatory hypopigmentation
  Postinflammatory hypopigmentation is a cutaneous condition characterized by decreased pigment in the skin following inflammation of the skin....
  
  
• Progressive macular hypomelanosis
  Progressive macular hypomelanosis
  Progressive macular hypomelanosis is a common skin condition, a disorder, observed more frequently in young women with darkly pigmented skin who originate from or reside in tropical climates....
  
  
• Quadrichrome vitiligo
  Quadrichrome vitiligo
  Quadrichrome vitiligo is another variant of vitiligo, a cutaneous condition, which reflects the presence of a fourth color at sites of perifollicular repigmentation.- See also :* Trichrome vitiligo* ABCD syndrome* List of cutaneous conditions...
  
  
• Reticular pigmented anomaly of the flexures (Dark dot disease, Dowling–Degos' disease)
• Reticulate acropigmentation of Kitamura
  Reticulate acropigmentation of Kitamura
  Reticulate acropigmentation of Kitamura consists of linear palmar pits and pigmented macules 1 to 4mm in diameter on the volar and dorsal aspects of the hands and feet, usually inherited in an autosomal-dominant fashion....
  
  
• Revesz syndrome
  Revesz syndrome
  Revesz syndrome is a fatal disease that causes exudative retinopathy and bone marrow failure. Other symptoms include severe aplastic anemia, intrauterine growth retardation, fine sparse hair, fine reticulate skin pigmentation, ataxia because of cerebellar hypoplasia, and cerebral calcifications...
  
  
• Riehl melanosis
  Riehl melanosis
  Riehl melanosis is a form of contact dermatitis, beginning with pruritus, erythema, and pigmentation that gradually spreads which, after reaching a certain extent, becomes stationary. The pathogenesis of Riehl melanosis is believed to be sun exposure following the use of some perfumes or creams ....
  
  
• Scratch dermatitis
  Scratch dermatitis
  Scratch dermatitis is a cutaneous condition characterized by linear hyperpigmented streaks are seen on the chest and back.- References :2. http://www.nejm.org/doi/full/10.1056/NEJMicm1002334...
  
   (Flagellate pigmentation from bleomycin)
• Segmental vitiligo
• Shah–Waardenburg syndrome
• Shiitake mushroom dermatitis
  Shiitake mushroom dermatitis
  Shiitake mushroom dermatitis is a cutaneous condition that occurs after eating large amounts of raw or partially cooked shiitake mushrooms....
  
   (Flagellate mushroom dermatitis, Mushroom worker's disease, Shiitake-induced toxicoderma)
• Tar melanosis
  Tar melanosis
  Tar melanosis is an occupational dermatosis that occurs among tar handlers after several years' exposure, characterized by a severe widespread itching that is soon followed by the appearance of reticular pigmentation, telangiectases, and a shiny appearance of the skin....
  
   (Melanodermatitis toxica lichenoides)
• Tietz syndrome
  Tietz syndrome
  Tietz syndrome, also called Tietz albinism-deafness syndrome or albinism and deafness of Tietz, is an autosomal dominant congenital disorder characterized by deafness and leucism. It is caused by a mutation in the microphthalmia-associated transcription factor gene...
  
  
• Titanium metallic discoloration
  Titanium metallic discoloration
  Titanium metallic discoloration has been reported to have occurred with titanium-containing ointment causing papules on the penis of a patient. Titanium screws used for orthopedic procedures, if they come in close proximity to the skin, can also causes cutaneous blue-black hyperpigmentation....
  
  
• Transient neonatal pustular melanosis
  Transient neonatal pustular melanosis
  Transient neonatal pustular melanosis is a cutaneous condition that presents at birth with 1- to 3-mm flaccid, superficial fragile pustules, some of which may have already resolved in utero, leaving pigmented macules....
  
   (Transient neonatal pustulosis, Lentigines neonatorum)
• Trichrome vitiligo
• Vagabond's leukomelanoderma
  Vagabond's leukomelanoderma
  Vagabond's leukomelanoderma is a skin disorder found in the elderly with a combination of dietary deficiency and lack of hygiene, resulting in an infestation of Pediculus humanus. It presents with hypermelanosis in the ankles, axillae, groin, inner thighs and the back of the neck....
  
  
• Vasospastic macule
  Vasospastic macule
  Vasospastic macules are a skin condition due to localized vasoconstriction and are seen most often in young women....
  
  
• Vitiligo
  Vitiligo
  Vitiligo is a condition that causes depigmentation of sections of skin. It occurs when melanocytes, the cells responsible for skin pigmentation, die or are unable to function. The cause of vitiligo is unknown, but research suggests that it may arise from autoimmune, genetic, oxidative stress,...
  
  
• Vitiligo ponctué
  Vitiligo ponctué
  Vitiligo ponctué is a cutaneous condition, an unusual form of vitiligo, characterized by small confetti-like or tiny, discrete macules that may occur on otherwise normal or unusually darkened skin....
  
  
• Vogt–Koyanagi–Harada syndrome
• Waardenburg syndrome
  Waardenburg syndrome
  Waardenburg syndrome Waardenburg syndrome Waardenburg syndrome (also Waardenburg­ Shah Syndrome, Waardenburg-Klein syndrome, Mende's syndrome II, Van der Hoeve-Halbertsma-Waardenburg syndrome, Ptosis-Epicanthus syndrome, Van der Hoeve-Halbertsma-Gualdi syndrome, Waardenburg type Pierpont,[5] Van...
  
  
• Wende–Bauckus syndrome
  Wende–Bauckus syndrome
  Wende–Bauckus syndrome is a cutaneous condition characterized by tiny white macules on the trunk with confluence within flexures....
  
   (Pegum syndrome)
• Woronoff's ring
  Woronoff's ring
  Woronoff's ring is a skin condition characterized by a blanched halo of approximately uniform width surrounding psoriatic lesions after phototherapy or topical treatments....
  
  
• X-linked reticulate pigmentary disorder
  X-linked reticulate pigmentary disorder
  X-linked reticulate pigmentary disorder is a cutaneous condition that has been described in adult women that had linear streaks of...
  
   (Familial cutaneous amyloidosis, Partington amyloidosis, Partington cutaneous amyloidosis, Partington syndrome type II, Reticulate pigmentary disorder, X-linked reticulate pigmentary disorder with systemic manifestations)
• Yemenite deaf-blind hypopigmentation syndrome
  Yemenite deaf-blind hypopigmentation syndrome
  Yemenite deaf-blind hypopigmentation syndrome is a condition caused by a mutation on the SRY-related HMG-box gene 10 .It was characterized in 1990.Some sources affirm SOX10 involvement....
  
  

Drug eruptions

Drug eruptions are adverse drug reaction

Adverse drug reaction

An adverse drug reaction is an expression that describes harm associated with the use of given medications at a normal dosage. ADRs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs...

s that present with cutaneous manifestations.

• Acrodynia (Calomel disease, Erythredemic polyneuropathy, Pink disease)
• Acute generalized exanthematous pustulosis
  Acute generalized exanthematous pustulosis
  Acute generalized exanthematous pustulosis is a not uncommon cutaneous reaction pattern that in 90% of cases is related to medication administration, characterized by a sudden eruption that appears on average five days after the medication is started.It is mediated by T cells.-Presentation:AGEP...
  
   (Pustular drug eruption, Toxic pustuloderma)
• Adverse reaction to biologic agents
  Adverse reaction to biologic agents
  Adverse reactions to biologic agents, such as imatinib, occur in more than 80% of patients, and can be characterized by edema and pruritus without dermatitis....
  
  
• Adverse reaction to cytokines
  Adverse reaction to cytokines
  Adverse reactions to cytokines are characterized by local inflammation and/or ulceration at the injection sites. Occasionally such reactions are seen with more widespread papular eruptions....
  
  
• Allopurinol hypersensitivity syndrome
  Allopurinol hypersensitivity syndrome
  Allopurinol hypersensitivity syndrome typically occurs in persons with preexisting renal failure. Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption.-References:...
  
  
• Anticoagulant-induced skin necrosis
  Anticoagulant-induced skin necrosis
  Anticoagulant-induced skin necrosis can be caused by both warfarin and heparin. Though by different mechanism, obese, postmenopausal woman have a predisposition. Skin lesions tend to occur in areas with abundant subcutaneous fat such as the breast, abdomen, and buttocks. Warfarin necrosis occurs...
  
  
• Anticonvulsant hypersensitivity syndrome
  Anticonvulsant hypersensitivity syndrome
  Anticonvulsant hypersensitivity syndrome can be seen with diphenylhydantoin, phenobarbital, carbamazepine, lamotrigine, and other anticonvulsants, characterized by a skin eruption that is initially morbilliform...
  
  
• Bromoderma
  Bromoderma
  Bromoderma, also known as bromoderma tuberosum, is a dermatological condition characterized by an eruption of papules and pustules on the skin. It is caused by hypersensitivity to bromides, such as those found in certain drugs. There is at least one reported case of bromoderma caused by excessive...
  
  
• Bullous drug reaction
  Bullous drug reaction
  Bullous drug reaction most commonly refers to a drug reaction in the erythema multiforme group...
  
   (Bullous drug eruption, Generalized bullous fixed drug eruption, Multilocular bullous fixed drug eruption)
• Chemotherapy-induced acral erythema (Palmoplantar erythrodysesthesia syndrome)
• Chemotherapy-induced hyperpigmentation
  Chemotherapy-induced hyperpigmentation
  Chemotherapy-induced hyperpigmentation is caused by many chemotherapeutic agents and the alkylating agents .-References:...
  
  
• Drug-induced acne
• Drug-induced angioedema
  Drug-induced angioedema
  Drug-induced angioedema is a known complication of the use of angiotensin-converting enzyme inhibitors and angiotensin II antagonists. The angioedema appears to be dose dependent as it may resolve with decreased dose....
  
  
• Drug-related gingival hyperplasia
  Drug-related gingival hyperplasia
  Drug-related gingival hyperplasia is a cutaneous condition characterized by enlargement of the gums noted during the first year of drug treatment....
  
  
• Drug-induced lichenoid reaction
  Drug-induced lichenoid reaction
  Drug-induced lichenoid reactions are skin eruptions that occur after ingestion, contact, or inhalation of certain chemicals, with the most common inducers being gold salts, beta blockers, antimalarials, thiazide diuretics, furosemide, spironolactone, and penicillamine...
  
   (Drug-induced lichen planus, Lichenoid drug eruption)
• Drug-induced lupus erythematosus
  Drug-induced lupus erythematosus
  Drug-induced lupus erythematosus is an autoimmune disorder caused by chronic use of certain drugs. These drugs cause an autoimmune response producing symptoms similar to those of SLE...
  
  
• Drug-induced nail changes
  Drug-induced nail changes
  Drug-induced nail changes are caused by drug administration which may result in a large number of nail abnormalities, usually with multiple nails being affected at the same time....
  
  
• Drug-induced pigmentation
  Drug-induced pigmentation
  Drug-induced pigmentation of the skin may occur as a consequence of drug administration, and the mechanism may be postinflammatory hyperpigmentation in some cases, but frequently is related to actual deposition of the offending drug in the skin....
  
  
• Drug-induced pseudolymphoma
  Drug-induced pseudolymphoma
  Drug-induced pseudolymphoma results from exposure to medications, which results in cutaneous inflammatory patterns that resemble lymphoma, most frequently mycosis fungoides....
  
  
• Drug-induced urticaria
  Drug-induced urticaria
  Drug-induced urticaria occurs by immunologic and nonimmunologic mechanisms, urticaria most commonly caused by aspirin and NSAIDs.- See also :* List of cutaneous conditions* Localized heat contact urticaria* Skin lesion...
  
  
• Erythema multiforme major
  Erythema multiforme major
  Erythema multiforme major is a term that may be used to refer to two conditions that constitute a spectrum of the same disease process:* Stevens–Johnson syndrome...
  
   (Erythema multiforme minor–erythema multiforme von Hebra)
• Exudative hyponychial dermatitis
  Exudative hyponychial dermatitis
  Exudative hyponychial dermatitis is a nail toxicity common during chemotherapy for breast cancer, especially if docetaxel is the chemotherapeutic regimen.-References:...
  
  
• Fixed drug reaction
  Fixed drug reaction
  Fixed drug reactions are common and so named because they recur at the same site with each exposure to a particular medication. Medications inducing fixed drug eruptions are usually those taken intermittently.-See also:*Skin lesion...
  
  
• Halogenoderma
  Halogenoderma
  Halogenodermas are skin eruptions that result after exposure to halogen-containing drugs or substances. This may last several weeks after drug use is discontinued. This is because of the slow elimination rate of iodides and bromides. -Treatment:...
  
  
• Heparin necrosis
  Heparin necrosis
  Heparin necrosis is a cutaneous condition and usually occurs between days 5 and 10 of heparin therapy....
  
  
• HIV disease-related drug reaction
  HIV disease-related drug reaction
  HIV disease-related drug reactions present in HIV-infected patients, especially those with helper T-cell counts between 25 and 200, immunosuppression that increases the risk for the development of adverse reactions to medications....
  
  
• Hydroxyurea dermopathy
  Hydroxyurea dermopathy
  Hydroxyurea dermopathy is caused by chronic use of hydroxyurea for chronic myelogenous leukemia, thrombocytopenia, or psoriasis, and presents with skin lesions characteristic of dermatomyositis.-References:...
  
  
• Injection site reaction
  Injection site reaction
  Injection site reactions are allergic reactions that result in cutaneous necrosis that may occur at sites of medication injection, typically presenting in one of two forms, those associated with intravenous infusion or those related to intramuscular injection. Intra muscular injections may...
  
  
• Iododerma
  Iododerma
  Iododermas are caused by iodides, with the most common sources of exposure being oral and intravenous contrast materials used to treat thyroid disease. The most common type of eruption is an acneiform eruption with numerous acutely inflamed follicular pustules, each surrounded by a ring of...
  
  
• Leukotriene receptor antagonist-associated Churg–Strauss syndrome
• Linear IgA bullous dermatosis
  Linear IgA bullous dermatosis
  Linear IgA bullous dermatosis is frequently associated with medication exposure, especially vancomycin, with men and women being equally affected. Linear IgA dermatosis is a rare immune-mediated blistering skin disease that may be divided into two types, chronic bullous disease of childhood and...
  
   (Linear IgA dermatosis)
• Photosensitive drug reaction
  Photosensitive drug reaction
  Photosensitive drug reaction secondary to medications may cause phototoxic, photoallergic, and lichenoid reactions, and photodistributed telangiectasias, as well as pseudoporphyria....
  
  
• Red man syndrome
• Scleroderma-like reaction to taxanes
  Scleroderma-like reaction to taxanes
  Scleroderma-like reaction to taxanes may occur in patients treated with docetaxel or paclitaxel, characterized by an acute, diffuse, infiltrated edema of the extremities and head.-References:...
  
  
• Serum sickness-like reaction
  Serum sickness-like reaction
  Serum sickness-like reactions refer to adverse reactions that have similar symptoms to serum sickness, but in which immune complexes are not found.- Pathogenesis :...
  
  
• Steroid acne
  Steroid acne
  Steroid acne is an adverse reaction to corticosteroids, and presents as small, firm follicular papules on the forehead, cheeks, and chest.-References:...
  
  
• Steroid folliculitis
  Steroid folliculitis
  Steroid folliculitis occurs following administration of glucocorticoids or corticotropin....
  
  
• Stevens–Johnson syndrome
• Sulfonamide hypersensitivity syndrome
  Sulfonamide hypersensitivity syndrome
  Sulfonamide hypersensitivity syndrome is similar to anticonvulsant hypersensitivity syndrome, but the onset is often sooner in the treatment course, generally after 7-14 days of therapy.It is considered immune-mediated.-References:...
  
  
• Texier's disease
  Texier's disease
  Texier's disease is a pseudosclerodermatous reaction that occurs after injection with vitamin K, a subcutaneous sclerosis with or without fasciitis that lasts several years.- References :...
  
  
• Toxic epidermal necrolysis
  Toxic epidermal necrolysis
  Toxic epidermal necrolysis is a rare, life-threatening dermatological condition that is usually induced by a reaction to medications...
  
   (Lyell's syndrome)
• Urticarial erythema multiforme
  Urticarial erythema multiforme
  Urticarial erythema multiforme is an unusual reaction virtually always associated with antibiotic ingestions, characterized by skin lesions that consist of urticarial papules and plaques, some of which clear centrally forming annular lesions, but with no true urticarial lesions.-References:...
  
  
• Vitamin K reaction
  Vitamin K reaction
  Vitamin K reactions occur after injection with vitamin K, and there are two patterns of presentation, a reaction may occur several days to 2 weeks after inection with skin lesions that are pruritic, red patches and plaques that can deep-seated, involving the dermis and subcutaneous tissue, or ...
  
  
• Warfarin necrosis
  Warfarin necrosis
  Warfarin-induced skin necrosis is a condition in which skin and subcutaneous tissue necrosis occurs due to acquired protein C deficiency following treatment with anti-vitamin K anticoagulants .Warfarin necrosis is a rare but severe complication of treatment with warfarin or related...
  
  

Endocrine-related

Endocrine conditions often present with cutaneous findings as the skin

Human skin

The human skin is the outer covering of the body. In humans, it is the largest organ of the integumentary system. The skin has multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments and internal organs. Human skin is similar to that of most other mammals,...

 interacts with the endocrine system

Endocrine system

In physiology, the endocrine system is a system of glands, each of which secretes a type of hormone directly into the bloodstream to regulate the body. The endocrine system is in contrast to the exocrine system, which secretes its chemicals using ducts. It derives from the Greek words "endo"...

 in many ways.

• Acanthosis nigricans associated with malignancy
  Acanthosis nigricans associated with malignancy
  Acanthosis nigricans associated with malignancy is the "malignant" type of acanthosis nigricans that may either precede , accompany , or follow the onset of an internal cancer...
  
   (Acanthosis nigricans type I)
• Acanthosis nigricans associated with obesity, insulin-resistant states, and endocrinopathy
  Acanthosis nigricans associated with obesity, insulin-resistant states, and endocrinopathy
  Acanthosis nigricans associated with obesity, insulin-resistant states, and endocrinopathy is the most common variety of acanthosis nigricans, presenting with a grayish, velvety thickening of the skin on the sides of the neck, axillae, and groins...
  
   (Acanthosis nigricans type III)
• Acral acanthosis nigricans
  Acral acanthosis nigricans
  Acral Acanthosis Nigricans also known as Acral Acanthotic Anomaly - Acral acanthosis nigricans is a common and thus important variant of Acanthosis nigricans. Classical acanthosis nigricans is characterized by hyperpigmented, velvety thickening of the skin typically on the nape and sides of the...
  
   (Acral acanthotic anomaly)
• Acral dry gangrene
  Acral dry gangrene
  Acral dry gangrene is a cutaneous condition characterized by necrosis of the fingertips or toes and may be associated with diabetes mellitus.- See also :* Diabetic dermadromes* Acanthosis nigricans* List of cutaneous conditions...
  
  
• Acromegaly
  Acromegaly
  Acromegaly is a syndrome that results when the anterior pituitary gland produces excess growth hormone after epiphyseal plate closure at puberty...
  
  
• Addison's disease
  Addison's disease
  Addison’s disease is a rare, chronic endocrine disorder in which the adrenal glands do not produce sufficient steroid hormones...
  
  
• Adrenal adenoma
  Adrenal adenoma
  A adrenal adenoma is a benign tumor of the glandular type in the adrenal gland. While some adrenal adenomas do not secrete hormones at all , some secrete cortisol , aldosterone , or androgens ....
  
  
• Adrenal carcinoma
• Adrenal hyperplasia
• Alopecia–nail dystrophy–ophthalmic complications–thyroid dysfunction–hypohidrosis–ephelides and enteropathy–respiratory tract infections syndrome (ANOTHER syndrome)
• Arrhenoblastoma
• Cretinism
  Cretinism
  Cretinism is a condition of severely stunted physical and mental growth due to untreated congenital deficiency of thyroid hormones usually due to maternal hypothyroidism.-Etymology and use of cretin:...
  
  
• Cushing's syndrome
  Cushing's syndrome
  Cushing's syndrome is a hormone disorder caused by high levels of cortisol in the blood. This can be caused by taking glucocorticoid drugs, or by tumors that produce cortisol or adrenocorticotropic hormone or CRH...
  
  
• Excess ovarian androgen release syndrome
  Excess ovarian androgen release syndrome
  Excess ovarian androgen release syndrome is a cutaneous condition usually seen in young women between the ages of 16 and 20....
  
   (Ovarian SAHA syndrome)
• Familial acanthosis nigricans
  Familial acanthosis nigricans
  Familial acanthosis nigricans is an exceedingly rare type of acanthosis nigricans that is present at birth or develop during childhood....
  
   (Acanthosis nigricans type II)
• Growth hormone deficiency
  Growth hormone deficiency
  Growth hormone deficiency is a medical condition in which the body does not produce enough growth hormone . Growth hormone, also called somatotropin, is a polypeptide hormone which stimulates growth and cell reproduction...
  
  
• Hyperandrogenism–insulin resistance–acanthosis nigricans syndrome (HAIR-AN syndrome)
• Hyperparathyroidism
  Hyperparathyroidism
  Hyperparathyroidism is overactivity of the parathyroid glands resulting in excess production of parathyroid hormone . The parathyroid hormone regulates calcium and phosphate levels and helps to maintain these levels...
  
  
• Hyperprolactinemic SAHA syndrome
  Hyperprolactinemic SAHA syndrome
  Hyperprolactinemic SAHA syndrome is a cutaneous condition characterized by lateral hairiness, oligomenorrhea, and sometimes acne, seborrhea, FAGA I, and even galactorrhea....
  
  
• Hyperthyroidism
  Hyperthyroidism
  Hyperthyroidism is the term for overactive tissue within the thyroid gland causing an overproduction of thyroid hormones . Hyperthyroidism is thus a cause of thyrotoxicosis, the clinical condition of increased thyroid hormones in the blood. Hyperthyroidism and thyrotoxicosis are not synonymous...
  
  
• Hypoparathyroidism
  Hypoparathyroidism
  Hypoparathyroidism is decreased function of the parathyroid glands with under production of parathyroid hormone. This can lead to low levels of calcium in the blood, often causing cramping and twitching of muscles or tetany , and several other symptoms...
  
  
• Hypothyroidism
  Hypothyroidism
  Hypothyroidism is a condition in which the thyroid gland does not make enough thyroid hormone.Iodine deficiency is the most common cause of hypothyroidism worldwide but it can be caused by other causes such as several conditions of the thyroid gland or, less commonly, the pituitary gland or...
  
  
• Leydig cell tumor
• Multiple endocrine neoplasia type 1
  Multiple endocrine neoplasia type 1
  Multiple endocrine neoplasia type 1 or Wermer's syndrome is part of a group of disorders that affect the endocrine system.-Explanation:...
  
   (Wermer syndrome)
• Multiple endocrine neoplasia type 2
  Multiple endocrine neoplasia type 2
  Multiple endocrine neoplasia type 2 is a group of medical disorders associated with tumors of the endocrine system. The tumors may be benign or malignant . They generally occur in endocrine organs Multiple endocrine neoplasia type 2 (also known as "Pheochromocytoma and amyloid producing medullary...
  
   (Multiple endocrine neoplasia type 2A, Pheochromocytoma and amyloid producing medullary thyroid carcinoma, PTC syndrome, Sipple syndrome)
• Multiple endocrine neoplasia type 3 (Mucosal neuromata with endocrine tumors, Multiple endocrine neoplasia type 2B, Multiple mucosal neuroma syndrome, Wagenmann–Froboese syndrome)
• Myxedema
  Myxedema
  Myxedema describes a specific form of cutaneous and dermal edema secondary to increased deposition of connective tissue components in subcutaneous tissue as seen in various forms of hypothyroidism and Graves' disease. It is more common in women than in men...
  
  
• Panhypopituitarism
• Persistent adrenarche syndrome
  Persistent adrenarche syndrome
  Persistent adrenarche syndrome is a cutaneous condition seen typically in thin young women who report great psychological and physical stress in their lives....
  
   (Adrenal SAHA syndrome)
• Polycystic ovarian syndrome
• Seborrhoea–acne–hirsutism–alopecia (SAHA syndrome)
• Thyroid acropachy
  Thyroid acropachy
  Thyroid acropachy is a cutaneous condition characterized by digital clubbing and swelling of digits and toes....
  
  

Eosinophilic

Eosinophilic cutaneous conditions encompass a wide variety of diseases that are characterized histologically by the presence of eosinophils in the inflammatory infiltrate and/or evidence of eosinophil degranulation

Degranulation

Degranulation is a cellular process that releases antimicrobial cytotoxic molecules from secretory vesicles called granules found inside some cells...

.

• Angiolymphoid hyperplasia with eosinophilia
  Angiolymphoid hyperplasia with eosinophilia
  Angiolymphoid hyperplasia with eosinophilia usually presents with pink to red-brown, dome-shaped, dermal papules or nodules of the head or neck,...
  
   (Epithelioid hemangioma, Histiocytoid hemangioma, Inflammatory angiomatous nodule, Inflammatory arteriovenous hemangioma, Intravenous atypical vascular proliferation, Papular angioplasia, Pseudopyogenic granuloma)
• Annular erythema of infancy
  Annular erythema of infancy
  Annular erythema of infancy is a skin condition reported in children roughly six months in age, characterized by transitory skin lesions that resolved without treatment within eleven months....
  
  
• Arthropod assault
  Arthropod assault
  Arthropod assault is a medical term describing a skin reaction to an insect bite characterized by inflammation and eosinophilic response....
  
  
• Churg–Strauss syndrome (Allergic granulomatosis)
• Eosinophilic cellulitis (Wells' syndrome)
• Eosinophilic fasciitis
  Eosinophilic fasciitis
  Eosinophilic fasciitis , also known as "Shulman's syndrome",is a form of fasciitis. It is distinguished from scleroderma primarily because the affected area is the fascia, not the dermis as in scleroderma...
  
   (Shulman's syndrome)
• Eosinophilic granuloma
• Eosinophilic pustular folliculitis of infancy
  Eosinophilic pustular folliculitis of infancy
  Eosinophilic pustular folliculitis of infancy is a cutaneous condition characterized by recurrent pruritic crops of follicular vesiculopustular lesions....
  
   (Eosinophilic pustular folliculitis in infancy, Infantile eosinophilic pustular folliculitis, Neonatal eosinophilic pustular folliculitis)
• Eosinophilic ulcer of the oral mucosa
  Eosinophilic ulcer of the oral mucosa
  Eosinophilic ulcer of the oral mucosa is a condition characterized by an ulcer with an indurated and elevated border....
  
   (Eosinophilic ulcer of the tongue, Riga–Fede disease, Traumatic eosinophilic granuloma)
• Eosinophilic vasculitis
  Eosinophilic vasculitis
  Eosinophilic vasculitis is a cutaneous condition characterized by an inflammation of blood vessels and the presence of eosinophils....
  
  
• Erythema toxicum neonatorum (Erythema toxicum, Toxic erythema of the newborn)
• Granuloma faciale
  Granuloma faciale
  Granuloma faciale is an uncommon benign chronic skin disease of unknown origin characterized by single or multiple cutaneous nodules, usually occurring over the face...
  
  
• Hypereosinophilic syndrome
  Hypereosinophilic syndrome
  The hypereosinophilic syndrome is a disease characterized by a persistently elevated eosinophil count in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow.HES is a diagnosis of exclusion, after clonal...
  
  
• Incontinentia pigmenti
  Incontinentia pigmenti
  Incontinentia Pigmenti is a genetic disorder that affects the skin, hair, teeth, nails, and central nervous system...
  
   (Bloch–Siemens syndrome, Bloch–Sulzberger disease, Bloch–Sulzberger syndrome)
• Itchy red bump disease
  Itchy red bump disease
  Itchy red bump disease is a cutaneous condition characterized by a red rash that may be treated with PUVA therapy....
  
   (Papular dermatitis)
• Juvenile xanthogranuloma
  Juvenile xanthogranuloma
  Juvenile xanthogranuloma is a form of histiocytosis, classified as "non-Langerhans cell histiocytosis", or more specifically, "type 2"....
  
  
• Kimura's disease
• Nodules–eosinophilia–rheumatism–dermatitis–swelling syndrome
  Nodules–eosinophilia–rheumatism–dermatitis–swelling syndrome
  Nodules–eosinophilia–rheumatism–dermatitis–swelling syndrome is a condition with similar features to Hypereosinophilic syndrome....
  
   (NERDS syndrome)
• Pachydermatous eosinophilic dermatitis
  Pachydermatous eosinophilic dermatitis
  Pachydermatous eosinophilic dermatitis is a cutaneous condition observed in South African black teenage girls, and characterized by generalized pruritic papules, hypertrophic genital lesions and peripheral eosinophilia....
  
  
• Papular eruption of blacks
  Papular eruption of blacks
  Papular eruption of blacks is a cutaneous condition characterized clinically by small, pruritic papules and histologically by a mononuclear cell-eosinophil perivascular infiltrate....
  
  
• Papuloerythroderma of Ofuji
  Papuloerythroderma of Ofuji
  Papuloerythroderma of Ofuji is a rare disorder most commonly found in Japan, characterized by pruritic papules that spare the skinfolds, producing bands of uninvolved cutis, creating the so-called deck-chair sign. Frequently there is associated blood eosinophilia...
  
  
• Pruritic papular eruption of HIV disease
  Pruritic papular eruption of HIV disease
  Pruritic papular eruption is characterized chronic pruritus and symmetric papular and pustular on the extensor surfaces of the arms, dorsum of the hands, trunk, and face with sparing of the palms and soles. with the absence of other definable causes of itching in an HIV infected patient. PPE...
  
  

Epidermal nevi, neoplasms, cysts

Epidermal nevi

Nevus

Nevus is the medical term for sharply-circumscribed and chronic lesions of the skin. These lesions are commonly named birthmarks and moles. Nevi are benign by definition...

, neoplasms, cyst

Cyst

A cyst is a closed sac, having a distinct membrane and division on the nearby tissue. It may contain air, fluids, or semi-solid material. A collection of pus is called an abscess, not a cyst. Once formed, a cyst could go away on its own or may have to be removed through surgery.- Locations :* Acne...

s are skin lesions that develop from the epidermal layer of the skin.

• Aberrant basal cell carcinoma
  Aberrant basal cell carcinoma
  Aberrant basal-cell carcinoma is a cutaneous condition characterized by a the formation of basal-cell carcinoma in the absence of any apparent carcinogenic factor, occurring in odd sites such as the scrotum, vulva, perineum, nipple, and axilla....
  
  
• Acanthoma fissuratum
  Acanthoma fissuratum
  Acanthoma fissuratum is a cutaneous condition characterized by local thickening of the skin in response to pressure caused by an eyeglass frame....
  
   (Granuloma fissuratum, Spectacle frame acanthoma)
• Acrospiroma
  Acrospiroma
  An acrospiroma is a tumor of the distal portion of a sweat gland. Acrospiromas are usually benign, and treatment consists of surgical excision....
  
   (Clear cell hidradenoma, Dermal duct tumor, Hidroacanthoma simplex, Nodular hidradenoma, Poroma)
• Actinic keratosis
  Actinic keratosis
  Actinic keratosis is a premalignant condition of thick, scaly, or crusty patches of skin. It is more common in fair-skinned people. It is associated with those who are frequently exposed to the sun, as it is usually accompanied by solar damage...
  
   (Senile keratosis, Solar keratosis)
• Adenoid squamous cell carcinoma
  Adenoid squamous cell carcinoma
  Adenoid squamous-cell carcinoma is a cutaneous condition, a subtype of squamous-cell carcinoma, characterized by a tubular microscopic pattern and keratinocyte acantholysis....
  
   (Pseudoglandular squamous cell carcinoma)
• Aggressive digital papillary adenocarcinoma
  Aggressive digital papillary adenocarcinoma
  Aggressive digital papillary adenocarcinoma is a cutaneous condition characterized by an aggressive malignancy involving the digit between the nailbed and the distal interphalangeal joint spaces....
  
   (Digital papillary adenocarcinoma, Papillary adenoma)
  
• Apocrine gland carcinoma
  Apocrine gland carcinoma
  Apocrine gland carcinoma is a cutaneous condition characterized by skin lesions which form in the axilla or anogenital regions.- See also :* Eccrine carcinoma* Primary cutaneous adenoid cystic carcinoma* Skin lesion...
  
  
• Apocrine nevus
  Apocrine nevus
  An Apocrine nevus is an extremely rare cutaneous condition that is composed of hyperplastic mature apocrine glands....
  
  
• Arsenical keratosis
  Arsenical keratosis
  An arsenical keratosis is a growth of keratin on the skin caused by arsenic, which occurs naturally in the earth's crust and is widely distributed in the environment, Arsenical compounds are used in industrial, agricultural, and medicinal substances...
  
  
• Atrophic actinic keratosis
• Balanitis plasmacellularis
  Balanitis plasmacellularis
  Balanitis plasmacellularis is a cutaneous condition characterized by a benign inflammatory skin lesion...
  
   (Balanoposthitis chronica circumscripta plasmacellularis, Balanitis circumscripta plasmacellularis, Plasma cell balanitis, Plasma cell vulvitis, Vulvitis circumscripta plasmacellularis, Zoon's balanitis, Zoon's erythroplasia, Zoon's vulvitis)
• Basal cell carcinoma
  Basal cell carcinoma
  Basal-cell carcinoma is the most common type of skin cancer. It rarely metastasizes or kills. However, because it can cause significant destruction and disfigurement by invading surrounding tissues, it is still considered malignant. Statistically, approximately 3 out of 10 Caucasians may develop a...
  
  
• Basaloid follicular hamartoma
  Basaloid follicular hamartoma
  A basaloid follicular hamartoma is a cutaneous condition characterized by distinctive benign adnexal tumor that has several described variants....
  
  
• Basaloid squamous cell carcinoma
  Basaloid squamous cell carcinoma
  Basaloid squamous-cell carcinoma is a cutaneous condition, a subtype of squamous-cell carcinoma, a virulent form characterized by a predilection for the tongue base....
  
  
• Birt–Hogg–Dubé syndrome
• Bowen's disease
  Bowen's disease
  Bowen's disease is a neoplastic skin disease, it can be considered as an early stage or intraepidermal form of squamous cell carcinoma. It was named after Mark Bowen...
  
   (Squamous cell carcinoma in situ)
• Ceruminoma
  Ceruminoma
  A ceruminoma is a benign tumor related to ceruminous glands, modified apocine glands located in the external ear.It does not describe the benign or malignant nature of the condition....
  
  
• Cicatricial basal cell carcinoma
  Cicatricial basal cell carcinoma
  Cicatricial basal-cell carcinoma is a cutaneous condition, a subtype of basal-cell carcinoma, and is an aggressive variant with a distinct clinical and histologic appearance....
  
   (Morpheaform basal cell carcinoma, Morphoeic basal cell carcinoma)
• Ciliated cyst of the vulva
  Ciliated cyst of the vulva
  Ciliated cyst of the vulva is a cutaneous condition characterized by a cyst of the vulva....
  
   (Cutaneous Müllerian cyst, Paramesonephric mucinous cyst of the vulva)
• Clear cell acanthoma
  Clear cell acanthoma
  Clear cell acanthoma is a benign clinical and histological lesion initially described as neoplastic, which some authors now regard as a reactive dermatosis...
  
   (Acanthome cellules claires of Degos and Civatte, Degos acanthoma, Pale cell acanthoma)
• Clear cell squamous cell carcinoma
  Clear cell squamous cell carcinoma
  Clear-cell squamous-cell carcinoma is a cutaneous condition, a subtype of squamous-cell carcinoma, characterized by keratinocytes that appear clear as a result of hydropic swelling....
  
   (Clear cell carcinoma of the skin)
• Chronic scar keratosis
  Chronic scar keratosis
  A Chronic scar keratosis is a precancerous skin lesion that arises within a long-standing scar....
  
   (Chronic cicatrix keratosis)
• Clonal seborrheic keratosis
  Clonal seborrheic keratosis
  Clonal seborrheic keratosis is a common benign cutaneous condition characterized by a skin lesion with a dull or lackluster surface, and with round, loosely packed nests of cells seen histologically....
  
  
• Common seborrheic keratosis
  Common seborrheic keratosis
  Common seborrheic keratosis is a common benign cutaneous condition characterized by a skin lesion with a dull or lackluster surface....
  
   (Basal cell papilloma, Solid seborrheic keratosis)
• Cowden syndrome
  Cowden syndrome
  Cowden syndrome is a rare autosomal dominant inherited disorder characterized by multiple tumor-like growths called hamartomas and an increased risk of certain forms of cancer....
  
   (Cowden's disease, Multiple hamartoma syndrome)
• Cutaneous ciliated cyst
  Cutaneous ciliated cyst
  Cutaneous ciliated cysts are a cutaneous condition characterized by solitary cysts located on the legs of females....
  
  
• Cutaneous columnar cyst
  Cutaneous columnar cyst
  Cutaneous columnar cysts are a cutaneous condition, a group of different cysts lined by columnar epithelium. Types of cysts included in this group are:* Bronchogenic cyst* Branchial cyst* Thyroglossal duct cyst* Cutaneous ciliated cyst* Median raphe cyst...
  
  
• Cutaneous horn
  Cutaneous horn
  Cutaneous horns, also known by the Latin name cornu cutaneum, are unusual keratinous skin tumors with the appearance of horns, or sometimes of wood or coral. Formally, this is a clinical diagnosis for a "conical projection above the surface of the skin." They are usually small and localized, but...
  
   (Cornu cutaneum)
• Cystic basal cell carcinoma
  Cystic basal cell carcinoma
  Cystic basal-cell carcinoma is a cutaneous condition characterized by dome-shaped, blue-gray cystic nodules....
  
  
• Dermal eccrine cylindroma (Cylindroma)
• Dermatosis papulosa nigra
  Dermatosis papulosa nigra
  Dermatosis papulosa nigra is a condition of many small, benign skin lesions on that face that closely simulate seborrheic keratoses, a condition generally presenting on dark-skinned individuals....
  
  
• Desmoplastic trichoepithelioma
  Desmoplastic trichoepithelioma
  A desmoplastic trichoepithelioma is a cutaneous condition characterized by a solitary, firm skin lesion on the face.- Treatment :Desmoplastic trichoepithelioma is benign tumor and can be managed safely with surgical removal, electrodesiccation and curettage....
  
  
• Dilated pore
  Dilated pore
  A dilated pore is a cutaneous condition characterized by a solitary, prominent, open comedo on the face or upper trunk of an elderly individual....
  
   (Dilated pore of Winer)
• Eccrine carcinoma
  Eccrine carcinoma
  Eccrine carcinoma is a rare cutaneous condition characterized by a plaque or nodule on the scalp, trunk, or extremities....
  
   (Syringoid carcinoma)
• Eccrine nevus
  Eccrine nevus
  An eccrine nevus is an extremely rare cutaneous condition that, histologically, is characterized by an increase in size or number of eccrine secretory coils....
  
  
• Epidermal cyst (Epidermal inclusion cyst, Epidermoid cyst, Infundibular cyst, Keratin cyst)
• Epidermal nevus syndrome
  Epidermal nevus syndrome
  Epidermal nevus syndrome was first described in 1968, and consists of extensive epidermal nevi with abnormalities of the CNS, skeleton, skin, cardiovascular system, gentiourinary system, and eyes...
  
   (Feuerstein and Mims syndrome, Solomon's syndrome)
• Epidermolytic acanthoma
  Epidermolytic acanthoma
  Epidermolytic acanthomas are a cutaneous condition characterized by discrete keratotic papules in adults....
  
  
• Eruptive vellus hair cyst
  Eruptive vellus hair cyst
  Eruptive vellus hair cysts are small lesions that occur most often in the chest wall, abdomen and extremities, often with a crusted surface. EVHC may occur randomly, or it can be inherited as an autosomal dominant trait. The condition affects males and females equally, and sporadic cases usually...
  
  
• Erythroplasia of Queyrat
  Erythroplasia of Queyrat
  Erythroplasia of Queyrat is a squamous cell carcinoma in situ of the glans penis.Like Bowen's Disease, it is associated with Human Papilloma Virus 16 and is a precursor for invasive squamous cell carcinoma.It is named for Louis Queyrat....
  
  
• Extramammary Paget's disease
  Extramammary Paget's disease
  Extramammary Paget’s disease , also Extramammary Paget disease, is a rare, slow-growing, usually non-invasive intraepithelial adenocarcinoma outside of the mammary gland and includes Paget's disease of the vulva and the extremely rare Paget's disease of the penis...
  
  
• Fibroepithelioma
• Fibroepithelioma of Pinkus
  Fibroepithelioma of Pinkus
  Fibroepithelioma of Pinkus is a cutaneous condition, a subtype of basal cell carcinoma, most commonly occurring on the lower back....
  
  
• Fibrofolliculoma
  Fibrofolliculoma
  Fibrofolliculomas are 2 to 4mm in diameter, dome-shaped, yellowish or skin-colored papules usually located on the head, neck, and upper trunk. They are characteristically seen in Birt–Hogg–Dubé syndrome....
  
  
• Follicular hybrid cyst
  Follicular hybrid cyst
  Follicular hybrid cyst is a cutaneous condition characterized by a cyst composed of several adnexal components....
  
   (Hybrid cyst)
• Folliculosebaceous-apocrine hamartoma
  Folliculosebaceous-apocrine hamartoma
  A folliculosebaceous-apocrine hamartoma, also known as "follicular-apocrine hamartoma", is a benign proliferation of the folliculosebaceous-apocrine unit....
  
   (Follicular-apocrine hamartoma)
• Folliculosebaceous cystic hamartoma
  Folliculosebaceous cystic hamartoma
  Folliculosebaceous cystic hamartoma abbreviated as is a rare cutaneous hamartoma consisting of dilated folliculosebaceous units invested in mesenchymal elements. it typically affects adults, have a predilection for the central face or scalp, with less than 1.5 cm dimension...
  
  
• Generalized eruptive keratoacanthoma
  Generalized eruptive keratoacanthoma
  220px|thumb|right| Picture of the face of a patient Generalized eruptive keratoacanthomas of GrzybowskiGeneralized eruptive keratoacanthoma is a cutaneous condition, a variant of keratoacanthomas, characterized by hundreds to thousands of tiny follicular keratotic papules over the entire body.-...
  
   (Generalized eruptive keratoacanthoma of Grzybowski)
• Giant solitary trichoepithelioma
  Giant solitary trichoepithelioma
  A giant solitary trichoepithelioma is a cutaneous condition characterized by a skin lesion that may be up to several centimeters in diameter....
  
  
• Hidradenoma
  Hidradenoma
  Hidradenoma is a cutaneous condition, and is a form of benign adnexal neoplasm that is a close relative of poroma....
  
   
  
• Hidradenocarcinoma
  Hidradenocarcinoma
  Hidradenocarcinoma is a cutaneous condition that may develop de novo or in association with an existent hidradenoma....
  
  
• Hidrocystoma
  Hidrocystoma
  Hidrocystoma is an adenoma of the sweat glands.Hidrocystomas are cysts of sweat ducts, usually on the eyelids.Histrocystomas are not tumours...
  
   (Cystadenoma, Moll's gland cyst, Sudoriferous cyst)
• Hydrocarbon keratosis
  Hydrocarbon keratosis
  A hydrocarbon keratosis is a precancerous keratotic skin lesion that occurs in people who have been occupationally exposed to polycyclic aromatic hydrocarbons....
  
   (Pitch keratosis, Tar keratosis, Tar wart)
• Hyperkeratosis lenticularis perstans (Flegel's disease)
• Hyperkeratosis of the nipple and areola
• Hyperkeratotic actinic keratosis
• Ichthyosis hystrix
  Ichthyosis hystrix
  The term ichthyosis hysterix is used to describe several rare skin disorders in the ichthyosis family of skin disorders characterized by massive hyperkeratosis with an appearance like spiny scales...
  
   (Ichthyosis hystrix gravior type Lambert, Porcupine man, Systematized verrucous nevus)
• Ichthyosis hystrix of Curth–Macklin
• Infiltrative basal cell carcinoma
  Infiltrative basal cell carcinoma
  Infiltrative basal-cell carcinoma is a cutaneous condition which is an aggressive type of basal-cell carcinoma characterized by deep infiltration....
  
  
• Inflammatory linear verrucous epidermal nevus
  Inflammatory linear verrucous epidermal nevus
  Inflammatory linear verrucous epidermal nevi are skin lesions that follow the lines of Blaschko, characterized histologically by hypergranulosis with orthokeratosis and parakeratosis with agranulosis....
  
  
• Inverted follicular keratosis
  Inverted follicular keratosis
  Inverted follicular keratosis is a cutaneous condition characterized by asymptomatic, firm, white–tan to pink papules....
  
  
• Irritated seborrheic keratosis
  Irritated seborrheic keratosis
  Irritated seborrheic keratosis is a common benign cutaneous condition characterized by a skin lesion with a dull or lackluster surface....
  
   (Basosquamous cell acanthoma, Inflamed seborrheic keratosis)
• Isthmicoma (Infundibuloma, Tumor of the follicular infundibulum)
• Juvenile myelomonocytic leukemia
  Juvenile myelomonocytic leukemia
  Juvenile myelomonocytic leukemia is a serious chronic leukemia that affects children mostly aged 4 and younger. The average age of patients at diagnosis is 2 years old. The World Health Organization has included JMML in the category of Myelodysplastic and Myeloproliferative disorders...
  
  
• Keratin implantation cyst
  Keratin implantation cyst
  Keratin implantation cysts are cysts lined by an epidermal sac and filled with a form of keratin. They are a primarily cutaneous condition, but they are occasionally observed under the nail , of a finger or toe....
  
  
• Keratoacanthoma
  Keratoacanthoma
  Keratoacanthoma is a common low-grade skin tumour that is believed to originate from the neck of the hair follicle. Many pathologists consider it to be a form of squamous cell carcinoma...
  
  
• Keratoacanthoma centrifugum marginatum
  Keratoacanthoma centrifugum marginatum
  Keratoacanthoma centrifugum marginatum is a cutaneous condition, a variant of keratoacanthomas, which is characterized by multiple tumors growing in a localized area.- See also :* Keratoacanthoma* Nail anatomy* List of cutaneous conditions...
  
  
• Large cell acanthoma
  Large cell acanthoma
  Large-cell acanthomas are a cutaneous condition characterized by small, skin-colored, hyper- or hypopigmented papules or plaques....
  
  
• Lichenoid actinic keratosis
• Lichenoid keratosis
  Lichenoid keratosis
  Lichenoid keratoses are a cutaneous condition characterized by brown to red, scaling maculopapules found on sun-exposed skin of extremities...
  
   (Benign lichenoid keratosis, Lichen planus-like keratosis, Solitary lichen planus, Solitary lichenoid keratosis)
• Linear verrucous epidermal nevus
  Linear verrucous epidermal nevus
  Linear verrucous epidermal nevus is a skin lesion characterized by a verrucous skin-colored, dirty-gray or brown papule. Generally, multiple papules present simultaneously, and coalesce to form a serpiginous plaque...
  
   (Linear epidermal nevus, Verrucous epidermal nevus)
• Malignant acrospiroma
  Malignant acrospiroma
  A malignant acrospiroma is a sweat gland carcinoma of the hand, which may recur locally in 50% of patients after excision, with distant metastases occurring in 60% of patients....
  
   (Malignant poroma, Porocarcinoma, Spiradenocarcinoma)
• Malignant mixed tumor
  Malignant mixed tumor
  A malignant mixed tumor is a cutaneous condition characterized by a tumor that favors the trunk and extremities....
  
   (Malignant chondroid syringoma)
• Malignant trichilemmal cyst
• Mantleoma
  Mantleoma
  Mantleoma is a benign neoplasm with mantle differentiation and they tend to occur on the face, early neoplasms consist only of cords and columns of undifferentiated epithelial cells....
  
  
• Marjolin's ulcer
  Marjolin's ulcer
  Marjolin's ulcer refers to an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatized, chronically inflamed, or scarred skin...
  
  
• Melanoacanthoma
  Melanoacanthoma
  Melanoacanthoma is a common, benign, darkly pigmented cutaneous condition characterized by a skin lesion with a dull or lackluster surface.It involves a proliferation of keratinocytes and melanocytes....
  
   (Pigmented seborrheic keratosis)
• Merkel cell carcinoma
  Merkel cell carcinoma
  Merkel cell carcinoma Merkel cell carcinoma Merkel cell carcinoma (also known as a "Cutaneous apudoma," "Primary neuroendocrine carcinoma of the skin," "Primary small cell carcinoma of the skin," and "Trabecular carcinoma of the skin"...
  
   (Cutaneous apudoma, Primary neuroendocrine carcinoma of the skin, Primary small cell carcinoma of the skin, Trabecular carcinoma of the skin)
• Microcystic adnexal carcinoma
  Microcystic adnexal carcinoma
  Microcystic adnexal carcinoma is a cutaneous condition characterized by a slow-growing plaque or nodule....
  
   (Sclerosing sweat duct carcinoma)
• Micronodular basal cell carcinoma
  Micronodular basal cell carcinoma
  Micronodular basal-cell carcinoma is a cutaneous condition characterized by a micronodular growth pattern....
  
  
• Milia en plaque
  Milia en plaque
  Milia en plaque is a cutaneous condition characterized by multiple milia within an erythematous edematous plaque....
  
  
• Milium
  Milium
  Milium can refer to* Milium , a genus of grasses* the singular form of Milia, a milk spot...
  
   
  
• Mixed tumor
  Mixed tumor
  A mixed tumor is a tumor derived from more than one type of tissue.Examples include pleomorphic adenoma and Mixed Müllerian tumor.-External links:* http://brighamrad.harvard.edu/Cases/bwh/hcache/379/full.html...
  
   (Chondroid syringoma)
• Mucinous carcinoma
  Mucinous carcinoma
  Mucinous carcinoma is a type of cancer that begins in cells that line certain internal organs and skin, and produce mucin ....
  
  
• Mucinous nevus
  Mucinous nevus
  Mucinous nevus is a rare cutaneous condition characterized by hamartoma that can be congenital or acquired....
  
   (Nevus mucinosus)
• Muir–Torre syndrome
• Multiple familial trichoepithelioma
  Multiple familial trichoepithelioma
  Multiple familial trichoepithelioma is a cutaneous condition characterized by multiple cystic and solid nodules appearing on the face.Types include:- References :...
  
   (Brooke–Spiegler syndrome, Epithelioma adenoides cysticum)
• Multiple keratoacanthomas
  Multiple keratoacanthomas
  Multiple keratoacanthomas is a cutaneous condition, a variant of keratoacanthomas, which is characterized by the appearance of multiple, sometimes hundreds of keratoacanthomas....
  
   (Ferguson Smith type of multiple self-healing keratoacanthomas, Multiple keratoacanthomas of the Ferguson–Smith type)
• Multiple minute digitate hyperkeratosis
  Multiple minute digitate hyperkeratosis
  Multiple minute digitate hyperkeratosis is a rare cutaneous condition, with about half of cases being familial, inherited in an autosomal dominant fashion, while the other half are sporadic.This disease has a unique histology, so a...
  
   (Digitate keratoses, Disseminated spiked hyperkeratosis, Familial disseminated piliform hyperkeratosis, Minute aggregate keratosis)
• Nevoid basal cell carcinoma syndrome
  Nevoid basal cell carcinoma syndrome
  Nevoid basal cell carcinoma syndrome , also known as basal cell nevus syndrome, multiple basal cell carcinoma syndrome, Gorlin syndrome, and Gorlin–Goltz syndrome, is an inherited medical condition involving defects within multiple body systems such as the skin, nervous system, eyes, endocrine...
  
   (Basal cell nevus syndrome, Gorlin syndrome, Gorlin–Goltz syndrome)
• Nevus comedonicus
  Nevus comedonicus
  Nevus comedonicus is characterized by closely arranged, grouped, often linear, slightly elevated papules that have at their center keratinous plugs resembling comedones....
  
   (Comedo nevus)
• Nevus comedonicus syndrome
  Nevus comedonicus syndrome
  Nevus comedonicus syndrome is a cutaneous condition characterized by a nevus comedonicus associated with cataracts, scoliosis, and neurologic abnormalities....
  
  
• Nevus sebaceous
  Nevus sebaceous
  Nevus sebaceous is a congenital, hairless plaque that typically occurs on the face or scalp. Such nevi are present at birth, affecting males and females of all races equally...
  
   (Nevus sebaceous of Jadassohn, Organoid nevus)
• Nevus unius lateris
  Nevus unius lateris
  Nevus unius lateris is a cutaneous condition, an epdiermal nevus in which the skin lesions are distrubted on one-half of the body....
  
  
• Nodular basal cell carcinoma
  Nodular basal cell carcinoma
  Nodular basal-cell carcinoma is a cutaneous condition, a subtype of basal-cell carcinoma, most commonly occurring on the sun-exposed areas of the head and neck....
  
   (Classic basal cell carcinoma)
• Paget's disease of the breast
  Paget's disease of the breast
  Paget's disease of the breast is a malignant condition that outwardly may have the appearance of eczema, with skin changes involving the nipple of the breast....
  
  
• Papillary eccrine adenoma
  Papillary eccrine adenoma
  Papillary eccrine adenoma is a cutaneous condition characterized by an uncommon benign sweat gland neoplasm that presents as a dermal nodule located primarily on the extremities of black patients....
  
   (Tubular apocrine adenoma)
• Papillary hidradenoma
  Papillary Hidradenoma
  A Papillary hidradenoma, also hidradenoma papilliferum, is a sharply circumscribed nodule of ectopic breast tissue usually found on the labia majora or the interlabial folds. It is benign tissue but is often confused clinically with carcinoma of the vulva because of its tendency to ulcerate...
  
   (Hidradenoma papilliferum)
• Papillomatosis cutis carcinoides
  Papillomatosis cutis carcinoides
  Papillomatosis cutis carcinoides is a cutaneous condition characterized by verrucous skin lesions, and is due to an HPV infection of the skin....
  
   (Papillomatosis cutis carcinoides of Gottron–Eisenlohr)
• Patch blue nevus
  Patch blue nevus
  A Patch blue nevus is a cutaneous condition characterized by a diffusely gray-blue area that may have superimposed darker macules....
  
   (Acquired dermal melanocytosis, Dermal melanocyte hamartoma)
• Perifollicular fibroma
  Perifollicular fibroma
  Perifollicular fibroma is a cutaneous condition, a benign tumor usually skin colored, most often affecting the face and upper trunk....
  
  
• Phakomatosis pigmentokeratotica
  Phakomatosis pigmentokeratotica
  Phakomatosis pigmentokeratotica is a cutaneous condition characterized by the combination of an organoid sebaceous nevus and speckled lentiginous nevus....
  
  
• Pigmented actinic keratosis
• Pigmented basal cell carcinoma
  Pigmented basal cell carcinoma
  Pigmented basal-cell carcinoma is a cutaneous condition, a subtype of basal-cell carcinoma, that exhibits increased melanization....
  
  
• Pigmented hairy epidermal nevus syndrome
  Pigmented hairy epidermal nevus syndrome
  Pigmented hairy epidermal nevus syndrome is a cutaneous condition characterized by a Becker nevus, ipsilateral hypoplasia of the breast, and skeletal defects such as scoliosis....
  
  
• Pilar sheath acanthoma
  Pilar sheath acanthoma
  A pilar sheath acanthoma is a cutaneous condition most often found on the face, particularly above the upper lip in adults....
  
  
• Pilonidal sinus (Barber's interdigital pilonidal sinus, Pilonidal cyst, Pilonidal disease)
• Polypoid basal cell carcinoma
  Polypoid basal cell carcinoma
  Polypoid basal-cell carcinoma is a cutaneous condition characterized by exophytic nodules on the head and neck....
  
  
• Pore-like basal cell carcinoma
  Pore-like basal cell carcinoma
  Pore-like basal-cell carcinoma is a cutaneous condition characterized by a basal-cell carcinoma that resembles an enlarged pore or stellate pit....
  
  
• Primary cutaneous adenoid cystic carcinoma
  Primary cutaneous adenoid cystic carcinoma
  Primary cutaneous adenoid cystic carcinoma is a cutaneous condition characterized by a tumor that usually presents on the chest, scalp, or vulva of middle- to older-aged persons....
  
  
• Proliferating epidermoid cyst
  Proliferating epidermoid cyst
  Proliferating epidermoid cysts are a cutaneous condition characterized by tumors that have deep invasion, and associated with anaplasia and a high mitotic rate....
  
   (Proliferating epithelial cyst)
• Proliferating trichilemmal cyst
  Proliferating trichilemmal cyst
  Proliferating trichilemmal cysts are a cutaneous condition characterized by proliferations of squamous cells forming scroll-like structures....
  
   (Pilar tumor, Proliferating follicular cystic neoplasm, Proliferating pilar tumor, Proliferating trichilemmal tumor)
• Pseudocyst of the auricle
  Pseudocyst of the auricle
  Pseudocyst of the auricle is a cutaneous condition characterized by a fluctuant, tense, noninflammatory swelling on the upper half of the ear....
  
   (Auricular endochondrial pseudocyst, Cystic chondromalacia, Endochondral pseudocyst, Intracartilaginous cyst)
• Pseudoepitheliomatous keratotic and micaceous balanitis
  Pseudoepitheliomatous keratotic and micaceous balanitis
  Pseudoepitheliomatous keratotic and micaceous balanitis is a cutaneous condition characterized by skin lesions on the glans penis that are wart-like with scaling.It can present as a cutaneous horn....
  
  
• PUVA keratosis
  PUVA keratosis
  A PUVA keratosis is a precancerous keratotic skin lesion that arises from exposure to psoralen plus ultraviolet A light therapy....
  
  
• Reactional keratosis
  Reactional keratosis
  A Reactional keratosis is a premalignant keratotic skin lesion that may arise in a variety of long-standing, nonscarring, inflammatory processes such as cutaneous lupus erythematosus for example....
  
  
• Reticulated seborrheic keratosis
  Reticulated seborrheic keratosis
  Reticulated seborrheic keratosis is a common benign cutaneous condition characterized by a skin lesion with a dull or lackluster surface, and with keratin cysts seen histologically....
  
   (Adenoid seborrheic keratosis)
• Rodent ulcer
  Rodent ulcer
  Rodent ulcer is a large skin lesion of nodular basal cell carcinoma with central necrosis. and is type of Basal cell carcinoma...
  
   (Jacobi ulcer)
• Schimmelpenning syndrome
  Schimmelpenning syndrome
  Schimmelpenning syndrome is a neurocutaneous condition characterized by one or more sebaceous nevi, usually appearing on the face or scalp, associated with anomalies of the central nervous system, ocular system, skeletal system, cardiovascular system, and genitourinary system.Synonyms include:...
  
   (Schimmelpenning–Feuerstein–Mims syndrome)
• Sebaceoma
  Sebaceoma
  Sebaceoma is a cutaneous condition that appears as a yellow or orange papule....
  
   (Sebaceous epithelioma)
• Sebaceous adenoma
  Sebaceous adenoma
  Sebaceous adenoma is a cutaneous condition characterized by a slow-growing tumour usually presenting as a pink, flesh-coloured, or yellow papule or nodule.-Significance:...
  
  
• Sebaceous carcinoma
  Sebaceous carcinoma
  Sebaceous carcinoma is an uncommon and aggressive malignant cutaneous tumor. Most are typically about 10 mm in size at presentation. This neoplasm is thought to arise from sebaceous glands in the skin and, therefore, may originate anywhere in the body where these glands are found. Because the...
  
  
• Sebaceous hyperplasia
  Sebaceous hyperplasia
  Sebaceous hyperplasia is a disorder of the sebaceous glands in which they become enlarged.producing yellow, shiny bumps on the face. These bumps are a natural response to the maternal hormones of pregnancy and usually resolve on their own within a few weeks after delivery.Sebaceous glands are...
  
  
• Sebaceous nevus syndrome
• Seboacanthoma
  Seboacanthoma
  Seboacanthomas are a cutaneous condition, and a specific type of sebaceous adenoma which may be specific to Muir–Torre syndrome....
  
  
• Seborrheic keratosis
  Seborrheic keratosis
  A seborrheic keratosis is a noncancerous benign skin growth that originates in keratinocytes. Like liver spots, seborrheic keratoses are seen more often as people age. In fact they are sometimes humorously referred to as the "barnacles of old age". They appear in various colors, from light tan to...
  
   (Seborrheic verruca, Senile wart)
• Seborrheic keratosis with squamous atypia
  Seborrheic keratosis with squamous atypia
  Seborrheic keratosis with squamous atypia is a less common cutaneous condition characterized by a skin lesion with a dull or lackluster surface, and with round, loosely packed nests of cells seen histologically....
  
  
• Signet-ring cell squamous cell carcinoma
  Signet-ring cell squamous cell carcinoma
  Signet ring cell squamous cell carcinoma is a cutaneous condition, a subtype of squamous cell carcinoma, characterized by concentric rings composed of keratin and large vacuoles corresponding to markedly dilated endoplasmic reticulum....
  
  
• Solitary keratoacanthoma
  Solitary keratoacanthoma
  A solitary keratoacanthoma is a benign, but rapidly growing, locally aggressive tumor which sometimes occur in the nail apparatus....
  
   (Subungual keratoacanthoma)
• Solitary trichoepithelioma
  Solitary trichoepithelioma
  A solitary trichoepithelioma is a cutaneous condition characterized by a firm dermal papules or nodules most commonly occurring on the face....
  
  
• Spindle cell squamous cell carcinoma
  Spindle cell squamous cell carcinoma
  Spindle-cell squamous-cell carcinoma is a cutaneous condition, a subtype of squamous-cell carcinoma, characterized by spindle-shaped atypical cells.- See also :* Pigmented spindle cell nevus...
  
   (Spindle cell carcinoma)
• Spiradenoma
  Spiradenoma
  Spiradenoma, also eccrine spiradenoma, is a cutaneous condition that is typically characterized, clinically, as a solitary, deep-seated dermal nodule of approximately one centimeter, occurring on the ventral surface of the body....
  
  
• Squamous cell carcinoma
  Squamous cell carcinoma
  Squamous cell carcinoma , occasionally rendered as "squamous-cell carcinoma", is a histologically distinct form of cancer. It arises from the uncontrolled multiplication of malignant cells deriving from epithelium, or showing particular cytological or tissue architectural characteristics of...
  
   
  
• Steatocystoma multiplex
  Steatocystoma multiplex
  Steatocystoma multiplex is a benign, autosomal dominant congenital condition resulting in multiple cysts on a person's body....
  
   (Epidermal polycystic disease, Sebocystomatosis)
• Steatocystoma simplex
  Steatocystoma simplex
  Steatocystoma simplex is a cutaneous condition characterized by a skin lesion that occurs with equal frequency in adult women and men, occurring on the face, trunk, or extremities....
  
   (Simple sebaceous duct cyst, Solitary steatocystoma)
• Stucco keratosis
  Stucco keratosis
  Stucco keratosis is a common benign cutaneous condition characterized by a skin lesion with a dull or lackluster surface, and with church-spire-like projections of epidermal cells around collagen seen histologically....
  
   (Digitate seborrheic keratosis, Hyperkeratotic seborrheic keratosis, Keratosis alba, Serrated seborrheic keratosis, Verrucous seborrheic keratosis)
• Superficial basal cell carcinoma
  Superficial basal cell carcinoma
  Superficial basal-cell carcinoma is a cutaneous condition, a subtype of basal-cell carcinoma, that occurs most commonly on the trunk and appears as an erythematous patch....
  
   (Superficial multicentric basal cell carcinoma)
• Syringadenoma papilliferum (Syringocystadenoma papilliferum)
• Syringofibroadenoma
  Syringofibroadenoma
  Syringofibroadenoma is a cutaneous condition characterized by a hyperkeratotic nodule or plaque involving the extremities.It is considered of eccrine origin....
  
   (Acrosyringeal nevus of Weedon and Lewis)
• Syringoma
• Systematized epidermal nevus
  Systematized epidermal nevus
  Systematized epidermal nevus is a cutaneous condition, an epidermal nevus with a diffuse or extensive distribution involving a large portion of a person's body surface....
  
  
• Thermal keratosis
  Thermal keratosis
  Thermal keratoses are keratotic skin lesions produced in the skin by exposure to infrared radiation....
  
  
• Trichilemmal carcinoma
  Trichilemmal carcinoma
  Trichilemmal carcinoma is a cutaneous condition reported to arise on sun-exposed areas, most commonly the face and ears.- See also :* Trichilemmoma* Skin lesionA similar tumor, although in the nail bed, is called onycholemmal....
  
  
• Trichilemmal cyst
  Trichilemmal cyst
  A trichilemmal cyst, also known as a wen, pilar cyst or isthmus-catagen cyst, is a common cyst that forms from a hair follicle. They are most often found on the scalp. The cysts are smooth, mobile and filled with keratin, a protein component found in hair, nails, and skin. They may or may not be...
  
   (Isthmus-catagen cyst, Pilar cyst)
• Trichilemmoma
  Trichilemmoma
  Trichilemmoma is a cutaneous condition, a benign neoplasm that differentiates toward cells of the outer root sheath.. The lesion is often seen in the face and neck region...
  
  
• Trichoadenoma
  Trichoadenoma
  A trichoadenoma is a cutaneous condition characterized by a solitary, rapidly growing skin lesion ranging from 3 to 15mm in diameter.- See also :* Dilated pore* Pilar sheath acanthoma* Skin lesion...
  
   (Trichoadenoma of Nikolowski)
• Trichoblastoma
  Trichoblastoma
  Trichoblastomas are a cutaneous condition characterized by benign neoplasms of follicular germinative cells. Trichoblastic fibroma is a designation used to characterize small nodular trichoblastomas with conspicuous fibrocytic stroma, sometimes constituting over 50% of the lesion....
  
  
• Trichoblastic fibroma
• Trichodiscoma
  Trichodiscoma
  A trichodiscoma is a cutaneous condition, a benign tumor usually skin colored, most often affecting the face and upper trunk....
  
  
• Trichofolliculoma
  Trichofolliculoma
  Trichofolliculoma is a cutaneous condition characterized by a benign, highly-structured tumor of the pilosebaceous unit.- See also :* Multiple familial trichoepithelioma* Pilomatricoma* Skin lesion* List of cutaneous conditions...
  
  
• Unilateral palmoplantar verrucous nevus
  Unilateral palmoplantar verrucous nevus
  A Unilateral palmoplantar verrucous nevus is a cutaneous condition that has features of pachyonychia congenita....
  
  
• Urethral caruncle
  Urethral caruncle
  A urethral caruncle is a benign cutaneous condition characterized by distal urethral lesions that are most commonly found in postmenopausal females.Urethral caruncles are frequently associated with atrophic genital epithelium in elderly patients. They can become a source of chronic hematuria,...
  
  
• Verrucous carcinoma
  Verrucous carcinoma
  Verrucous carcinoma is an uncommon variant of squamous cell carcinoma. This form of cancer is often seen in those who chew tobacco or use snuff orally, so much so that it is sometimes referred to as "Snuff dipper's cancer."Most patients with verrucous carcinoma have a good prognosis...
  
   (Ackerman tumor, Carcinoma cuniculatum)
• Verrucous cyst
  Verrucous cyst
  Verrucous cysts are a cutaneous condition that resemble epidermoid cysts except that the lining demonstrates papillomatosis....
  
   (Cystic papilloma)
• Viral keratosis
• Warty dyskeratoma
  Warty dyskeratoma
  Warty dyskeratoma, also known as an Isolated dyskeratosis follicularis,) is a benign epidermal proliferation with distinctive histologic findings that may mimic invasive squamous cell carcinoma and commonly manifests as an umbilicated lesion with a keratotic plug, WD have some histopathologic...
  
   (Isolated dyskeratosis follicularis)
• Waxy keratosis of childhood
  Waxy keratosis of childhood
  Waxy keratosis of childhood is a keratotic, flesh-colored papule that is either sporadic or familial, and may be generalized or segmental....
  
   (Kerinokeratosis papulosa)
• Zoon's vulvitis
• Zosteriform speckled lentiginous nevus
  Zosteriform speckled lentiginous nevus
  Zosteriform speckled lentiginous nevus is a skin lesion that may be the result of a potentially lethal mutation.The terminology has been described as "confusing".It was characterized in 1981....
  
  

Erythemas

Erythema

Erythema

Erythema is redness of the skin, caused by hyperemia of the capillaries in the lower layers of the skin. It occurs with any skin injury, infection, or inflammation...

s are reactive skin conditions in which there is blanchable

Blanch (medical)

When skin is blanched, it takes on a whitish appearance as blood flow to the region is prevented. This occurs during and is the basis of the physiologic test known as diascopy....

 redness.

• Erythema annulare centrifugum
  Erythema annulare centrifugum
  Erythema annulare centrifugum is a descriptive term for a skin lesion. The lesions form consists of redness in a ring form that spreads from the center . EAC was first described by Darier in 1916...
  
   (Deep gyrate erythema, Erythema perstans, Palpable migrating erythema, Superficial gyrate erythema)
• Erythema gyratum repens
  Erythema gyratum repens
  Erythema gyratum repens is a figurate erythema that is rapidly moving and usually a cancer marker.- References :...
  
   (Gammel's disease)
• Erythema migrans
  Erythema migrans
  Erythema chronicum migrans refers to the rash often seen in the early stage of Lyme disease. It can appear anywhere from one day to one month after a tick bite. This rash does not represent an allergic reaction to the bite, but rather an actual skin infection with the Lyme bacteria, Borrelia...
  
   (Erythema chronicum migrans)
• Erythema multiforme
  Erythema multiforme
  Erythema multiforme is a skin condition of unknown cause, possibly mediated by deposition of immune complex in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure...
  
  
• Erythema multiforme minor
  Erythema multiforme minor
  Erythema multiforme minor is a skin condition associated with a preceding herpetic infection, characterized by skin lesions that begin as sharply marginated, erythematous macules, which then become raised and develop a target-like appearance.Erythema multiforme minor is sometimes divided into...
  
   (Herpes simplex-associated erythema multiforme)
• Erythema palmare
• Generalized erythema
  Generalized erythema
  Generalized erythema is a skin condition that may be caused by medications, bacterial toxins, or viral infections....
  
  
• Necrolytic acral erythema
  Necrolytic acral erythema
  Necrolytic acral erythema is a cutaneous condition that is a manifestation of hepatitis C viral infection....
  
  
• Necrolytic migratory erythema
  Necrolytic migratory erythema
  Necrolytic migratory erythema is a red, blistering rash that spreads across the skin, particularly the lower abdomen, buttocks, perineum, and groin...
  
   (Glucagonoma syndrome)

Genodermatoses

Genodermatoses are inherited

Heredity

Heredity is the passing of traits to offspring . This is the process by which an offspring cell or organism acquires or becomes predisposed to the characteristics of its parent cell or organism. Through heredity, variations exhibited by individuals can accumulate and cause some species to evolve...

 genetic skin conditions often grouped into three categories: chromosomal

Chromosome

A chromosome is an organized structure of DNA and protein found in cells. It is a single piece of coiled DNA containing many genes, regulatory elements and other nucleotide sequences. Chromosomes also contain DNA-bound proteins, which serve to package the DNA and control its functions.Chromosomes...

, single gene

Gene

A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

, and polygenetic.

• 18q deletion syndrome
• Acrodermatitis enteropathica
  Acrodermatitis enteropathica
  Acrodermatitis enteropathica is an autosomal recessive metabolic disorder affecting the uptake of zinc, characterized by periorificial and acral dermatitis, alopecia , and diarrhea....
  
  
• Acrogeria
  Acrogeria
  Acrogeria is a cutaneous condition characterized by premature aging.It was characterized in 1940.A bruising tendency has been observed....
  
   (Gottron syndrome)
• Acrokeratosis verruciformis
  Acrokeratosis verruciformis
  Acrokeratosis verruciformis is a rare autosomal dominant disorder appearing at birth or in early childhood, characterized by skin lesions that are small, verrucous, flat papules resembling warts....
  
   (Acrokeratosis verruciformis of Hopf)
• Adams–Oliver syndrome
• Adducted thumbs syndrome
  Adducted thumbs syndrome
  Adducted thumbs syndrome is a condition inherited in an autosomal recessive fashion, characterized by arthrogryposis, craniosynostosis, and myopathy in association with congenital generalized hypertrichosis....
  
  
• Albright's hereditary osteodystrophy
  Albright's hereditary osteodystrophy
  Albright’s hereditary osteodystrophy is form of osteodystrophy, otherwise known as Pseudohypoparathyroidism type 1a.-Characteristics:The disorder is characterized by a lack of responsiveness to parathyroid hormone, resulting in low serum calcium, high serum phosphate, and appropriately high serum...
  
  
• Angelman syndrome
  Angelman syndrome
  Angelman syndrome is a neuro-genetic disorder characterized by intellectual and developmental delay, sleep disturbance, seizures, jerky movements , frequent laughter or smiling, and usually a happy demeanor....
  
  
• Apert syndrome
  Apert syndrome
  Apert syndrome is a form of acrocephalosyndactyly, a congenital disorder characterized by malformations of the skull, face, hands and feet. It is classified as a branchial arch syndrome, affecting the first branchial arch, the precursor of the maxilla and mandible...
  
   (Acrocephalosyndactyly)
• Arthrogryposis–renal dysfunction–cholestasis syndrome
  Arthrogryposis–renal dysfunction–cholestasis syndrome
  Arthrogryposis–renal dysfunction–cholestasis syndrome is a cutaneous condition caused by a mutation in the VPS33B gene....
  
   (ARC syndrome)
• Ataxia telangiectasia
  Ataxia telangiectasia
  Ataxia telangiectasia is a rare, neurodegenerative, inherited disease that affects many parts of the body and causes severe disability. Ataxia refers to poor coordination and telangiectasia to small dilated blood vessels, both of which are hallmarks of the disease...
  
   (Louis–Bar syndrome)
• Atrichia with papular lesions
  Atrichia with papular lesions
  Atrichia with papular lesions is a diffuse hair loss caused by an abnormality of the human homologue of the mouse hairless gene.It is associated with HR....
  
  
• Atrophodermia vermiculata
  Atrophodermia vermiculata
  Atrophodermia vermiculata Atrophodermia vermiculata Atrophodermia vermiculata (also known as "Acne vermoulante," "Acne vermoulanti," "Atrophoderma reticulata symmetrica faciei," "Atrophoderma reticulatum," "Atrophoderma vermiculata," "Atrophoderma vermiculatum," "Atrophodermia reticulata symmetrica...
  
   (Acne vermoulante, Acne vermoulanti, Atrophoderma reticulata symmetrica faciei, Atrophoderma reticulatum, Atrophoderma vermiculata, Atrophoderma vermiculatum, Atrophodermia reticulata symmetrica faciei, Atrophodermia ulerythematosa, Atrophodermie vermiculée des joues avec kératoses folliculaires, Folliculitis ulerythema reticulata, Folliculitis ulerythematous reticulata, Folliculitis ulerythemosa, Honeycomb atrophy, Ulerythema acneforme, Ulerythema acneiforme)
• Autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy syndrome (APECED syndrome)
• Bart syndrome
  Bart syndrome
  Bart syndrome is a genetic disorder characterized by the association of congenital localized absence of skin, epidermolysis bullosa, lesions of the mouth mucosa, and dystrophic nails.-Genetics:...
  
  
• Bazex–Dupré–Christol syndrome (Bazex syndrome, Follicular atrophoderma and basal cell cacinomas)
• Bloom syndrome
  Bloom syndrome
  Bloom's syndrome , also known as Bloom–Torre–Machacek syndrome, is a rare autosomal recessive chromosomal disorder characterized by a high frequency of breaks and rearrangements in an affected person's chromosomes. The condition was discovered and first described by dermatologist Dr...
  
   (Bloom–Torre–Machacek syndrome)
• Blue rubber bleb nevus syndrome
  Blue rubber bleb nevus syndrome
  Blue rubber bleb nevus syndrome is a rare disorder that consists mainly of abnormal blood vessels affecting the gastrointestinal tract....
  
  
• Brittle hair–intellectual impairment–decreased fertility–short stature syndrome (BIDS syndrome)
• Cantú syndrome
  Cantú syndrome
  Cantú syndrome is a condition characterized by hypertrichosis, osteochondrodysplasia, and cardiomegaly....
  
  
• Cardio-facio-cutaneous syndrome (Cardiofaciocutaneous syndrome)
• Cartilage–hair hypoplasia
  Cartilage–hair hypoplasia
  Cartilage–hair hypoplasia , also known as McKusick type metaphyseal chondrodysplasia, is a rare form of short-limbed dwarfism due to skeletal dysplasia. It was first reported in 1965 by McKusick et al...
  
   (McKusick type metaphyseal chondrodysplasia)
• Cerebral dysgenesis–neuropathy–ichthyosis–keratoderma syndrome
  Cerebral dysgenesis–neuropathy–ichthyosis–keratoderma syndrome
  Cerebral dysgenesis–neuropathy–ichthyosis–keratoderma syndrome is a cutaneous condition caused by mutation in the SNAP29 gene.- See also :* Arthrogryposis–renal dysfunction–cholestasis syndrome* List of cutaneous conditions...
  
   (CEDNIK syndrome)
• Childhood tumor syndrome
  Childhood tumor syndrome
  Childhood tumor syndrome is a condition characterized by axillary freckling, neurofibromas and/or CNS gliomas....
  
  
• Chondrodysplasia punctata
  Chondrodysplasia punctata
  Chondrodysplasia punctata is a clinically and genetically diverse group of rare diseases, first described by Conradi, that share the features of stippled epiphyses and skeletal changes.Types include:* Rhizomelic chondrodysplasia punctata , ,...
  
  
• Cicatricial junctional epidermolysis bullosa
  Cicatricial junctional epidermolysis bullosa
  Cicatricial junctional epidermolysis bullosa is a skin condition characterized by blisters that heal with scarring.It was characterized in 1985.It is not included in OMIM....
  
  
• Craniosynostosis–anal anomalies–porokeratosis syndrome
  Craniosynostosis–anal anomalies–porokeratosis syndrome
  Craniosynostosis–anal anomalies–porokeratosis syndrome is a cutaneous condition inherited in an autosomal recessive fashion.- See also :* Cerebral dysgenesis–neuropathy–ichthyosis–keratoderma syndrome...
  
   (CAP syndrome)
• Cockayne syndrome
  Cockayne syndrome
  Cockayne syndrome is a rare autosomal recessive, congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight , and premature aging...
  
  
• Colobomas of the eye–heart defects–ichthyosiform dermatosis–mental retardation–ear defects syndrome (CHIME syndrome, Zunich neuroectodermal syndrome, Zunich–Kaye syndrome)
• Congenital hemidysplasia with ichthyosiform erythroderma and limb defects syndrome (CHILD syndrome)
• Conradi–Hünermann syndrome (Conradi–Hünermann–Happle syndrome, Happle syndrome, X-linked dominant chondrodysplasia punctata)
• Costello syndrome
  Costello syndrome
  Costello syndrome, also called faciocutaneoskeletal syndrome or FCS syndrome, is a rare genetic disorder that affects many parts of the body. It is characterized by delayed development and mental retardation, distinctive facial features, unusually flexible joints, and loose folds of extra skin,...
  
  
• Cronkhite–Canada syndrome
• Crouzon syndrome
  Crouzon syndrome
  Crouzon syndrome is a genetic disorder known as a branchial arch syndrome. Specifically, this syndrome affects the first branchial arch, which is the precursor of the maxilla and mandible...
  
  
• Cutis verticis gyrata
  Cutis verticis gyrata
  Cutis verticis gyrata is a superficial medical condition usually associated with thickening of the scalp. The condition was first described by Alibert in 1837...
  
  
• Darier's disease
  Darier's disease
  Darier's disease , also known as Darier disease, Darier–White disease, Dyskeratosis follicularis and Keratosis follicularis, is an autosomal dominant disorder discovered by French dermatologist Ferdinand-Jean Darier. Darier's is characterized by dark crusty patches on the skin, sometimes containing...
  
   (Darier–White disease, Dyskeratosis follicularis, Keratosis follicularis)
• DeSanctis–Cacchione syndrome
  DeSanctis–Cacchione syndrome
  DeSanctis–Cacchione syndrome is an extremely rare disorder characterized by the skin and eye symptoms of xeroderma pigmentosum occurring in association with microcephaly, progressive mental retardation, retarded growth and sexual development, deafness, choreoathetosis, ataxia and...
  
  
• Disseminated superficial actinic porokeratosis
  Disseminated superficial actinic porokeratosis
  Disseminated superficial actinic porokeratosis is a non-contagious skin condition with apparent genetic origin in the SART3 gene. It most often presents in sun-exposed areas of the body. Some DSAP cases have been reported in patients with acute immune compromised situations, particularly in the...
  
  
• Disseminated superficial porokeratosis
  Disseminated superficial porokeratosis
  Disseminated superficial porokeratosis is a more generalized processes than porokeratosis Mibelli, and involves mainly the exptremities in a bilateral, symmetric fashion. In about 50% of cases, skin lesions only develop in sun-exposed areas, and this is referred to as disseminated superficial...
  
  
• Dolichol kinase deficiency
  Dolichol kinase deficiency
  Dolichol kinase deficiency is a cutaneous condition caused by a mutation in the dolichol kinase gene.It is also known as Congenital disorder of glycosylation 1m....
  
  
• Dominant dystrophic epidermolysis bullosa
  Dominant dystrophic epidermolysis bullosa
  Dominant dystrophic epidermolysis bullosa is a skin condition characterized by vesicles and bullae on the extensor surfaces of the extremities....
  
  
• Dyskeratosis congenita
  Dyskeratosis congenita
  Dyskeratosis congenita , also called Zinsser-Cole-Engman syndrome, is a rare progressive congenital disorder which results in what in some ways resembles premature aging...
  
   (Zinsser–Cole–Engman syndrome)
• Dystrophic epidermolysis bullosa
• Ectodermal dysplasia
  Ectodermal dysplasia
  Ectodermal dysplasia is not a single disorder, but a group of syndromes all deriving from abnormalities of the ectodermal structures. More than 150 different syndromes have been identified. Despite some of the syndromes having different genetic causes the symptoms are sometimes very similar...
  
  
• Ectodermal dysplasia with corkscrew hairs
  Ectodermal dysplasia with corkscrew hairs
  Ectodermal dysplasia with corkscrew hairs is a skin condition with salient features including exaggerated pili torti, scalp keloids, follicular plugging, keratosis pilaris, xerosis, eczema, palmoplantar keratoderma, syndactyly, onchodysplasia, and conjunctival neovascularization....
  
  
• Ectrodactyly–ectodermal dysplasia–cleft syndrome (EEC syndrome, Split hand–split foot–ectodermal dysplasia–cleft syndrome)
• Epidermolysis bullosa herpetiformis
  Epidermolysis bullosa herpetiformis
  Epidermolysis bullosa herpetiformis is a skin condition that presents at birth with a generalized distribution, often with oral mucosa involvement and variable lesions in infancy....
  
   (Dowling–Meara epidermolysis bullosa simplex)
• Epidermolysis bullosa simplex
  Epidermolysis bullosa simplex
  Epidermolysis bullosa simplex is a disorder resulting from mutations in the genes encoding keratin 5 or keratin 14.Blister formation of EBS occurs at the dermoepidermal junction. Sometimes EBS is called epidermolytic.-Subtypes:...
  
  
• Epidermolysis bullosa simplex of Ogna
  Epidermolysis bullosa simplex of Ogna
  Epidermolysis bullosa simplex of Ogna is a skin condition with onset in infancy, presenting with seasonal blistering on acral areas during summer months....
  
  
• Epidermolysis bullosa simplex with mottled pigmentation
  Epidermolysis bullosa simplex with mottled pigmentation
  Epidermolysis bullosa simplex with mottled pigmentation is a skin condition resulting from a recurrent mutation in KRT14....
  
  
• Epidermolysis bullosa simplex with muscular dystrophy
  Epidermolysis bullosa simplex with muscular dystrophy
  Epidermolysis bullosa simplex with muscular dystrophy is a rare clinical entity, and is the first and only epidermolytic epidermolysis bullosa described that is not caused by a keratin mutation, presenting as a generalized intraepidermal blistering similar to the Koebner variant of generalized...
  
  
• Epidermolytic hyperkeratosis
  Epidermolytic hyperkeratosis
  Epidermolytic hyperkeratosis, is a rare skin disease in the ichthyosis family affecting around 1 in 250,000 people.It involves the clumping of keratin filaments.-Presentation:At birth, affected babies are called "enfant...
  
   (Bullous congenital ichthyosiform erythroderma, Bullous ichthyosiform erythroderma)
• Erythrokeratodermia with ataxia
  Erythrokeratodermia with ataxia
  Erythrokeratodermia with ataxia is a condition characterized by erythematous, hyperkeratotic plaques with fine, white, attached scales distributed almost symmetrically on the extremities....
  
   (Giroux–Barbeau syndrome)
• Familial benign chronic pemphigus (Familial benign pemphigus, Hailey–Hailey disease)
• Fanconi syndrome
  Fanconi syndrome
  Falconi syndrome is a disease of the proximal renal tubules of the kidney in which glucose, amino acids, uric acid, phosphate and bicarbonate are passed into the urine, instead of being reabsorbed. Fanconi syndrome affects the proximal tubule, which is the first part of the tubule to process fluid...
  
   (Familial pancytopenia, Familial panmyelophthisis)
• Focal dermal hypoplasia
  Focal dermal hypoplasia
  Focal dermal hypoplasia is a form of ectodermal dysplasia.It is also known as Goltz-Gorlin syndrome, after Robert Goltz and Robert Gorlin.It has been associated with PORCN, on the X chromosome.-External links:...
  
   (Goltz syndrome)
• Follicular atrophoderma
  Follicular atrophoderma
  Follicular atrophoderma is a skin condition consisting of follicular indentations without hairs, notably occurring on extensor surfaces of the hands, legs, and arms.-References:...
  
  
• Franceschetti–Klein syndrome (Mandibulofacial dysostosis)
• Gardner's syndrome
  Gardner's syndrome
  Gardner syndrome, also known as familial colorectal polyposis, is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with tumors outside the colon...
  
   (Familial colorectal polyposis)
• Gastrocutaneous syndrome
  Gastrocutaneous syndrome
  Gastrocutaneous syndrome is a rare autosomal dominant cutaneous condition characterized by multiple lentigines....
  
  
• Generalized atrophic benign epidermolysis bullosa
  Generalized atrophic benign epidermolysis bullosa
  Generalized atrophic benign epidermolysis bullosa is a skin condition that is characterized by onset at birth, generalized blisters and atrophy, mucosal involvement, and thickened, dystrophic, or absent nails....
  
  
• Generalized epidermolysis bullosa simplex
  Generalized epidermolysis bullosa simplex
  Generalized epidermolysis bullosa simplex is a skin condition that presents at birth to early infancy with a predilection for the hands, feet, and extremities, and palmar-plantar hyperkeratosis and erosions may be present....
  
   (Koebner variant of generalized epidermolysis bullosa simplex)
• Generalized trichoepithelioma
  Generalized trichoepithelioma
  Generalized trichoepitheliomas are characterized histologically by replacement of the hair follicles by trichoepithelioma-like epithelial proliferations associated with hyperplastic sebaceous glands....
  
  
• Giant axonal neuropathy with curly hair
  Giant axonal neuropathy with curly hair
  Giant axonal neuropathy with curly hair is an autosomal recessive condition due to mutations in gigaxonin.- References :...
  
  
• Gingival fibromatosis with hypertrichosis
  Gingival fibromatosis with hypertrichosis
  Gingival fibromatosis with hypertrichosis is a cutaneous condition characterized by dark terminal hairs on the peripheral face, central back, and extremities. It is a RASopathy....
  
  
• Haber syndrome
  Haber syndrome
  Haber syndrome is a cutaneous disorder of hyperpigmentation characterized by reticulated pigmentation of the person's skin. A rare genodermatosis, its key features include "rosacea-like facial eruption[,] reticulated hyperpigmentation of major flexures, comedones on the back and neck, and pitted...
  
  
• Hallerman–Streiff syndrome
• Harlequin-type ichthyosis (Harlequin baby, Harlequin fetus, Harlequin ichthyosis, Ichthyosis congenita, Ichthyosis congenita gravior)
• Hay–Wells syndrome (AEC syndrome, Ankyloblepharon filiforme adnatum–ectodermal dysplasia–cleft palate syndrome, Ankyloblepharon–ectodermal defects–cleft lip and palate syndrome, Ankyloblepharon–ectodermal dysplasia–clefting syndrome)
• Hereditary sclerosing poikiloderma
  Hereditary sclerosing poikiloderma
  Hereditary sclerosing poikiloderma is an autosomal dominant conditions with skin changes consisting of generalized poikiloderma appearing in childhood....
  
   
  
• Heterochromia iridum
• Holocarboxylase synthetase deficiency
  Holocarboxylase synthetase deficiency
  Holocarboxylase synthetase deficiency is an inherited metabolic disorder in which the body is unable to use the vitamin biotin effectively. This disorder is classified as a multiple carboxylase deficiency, a group of disorders characterized by impaired activity of certain enzymes that depend on...
  
  
• Hypohidrotic ectodermal dysplasia
  Hypohidrotic ectodermal dysplasia
  Hypohidrotic ectodermal dysplasia is one of about 150 types of ectodermal dysplasia in humans...
  
   (Anhidrotic ectodermal dysplasia, Christ–Siemens–Touraine syndrome)
• Hypotrichosis–acro-osteolysis–onychogryphosis–palmoplantar keratoderma–periodontitis syndrome
  Hypotrichosis–acro-osteolysis–onychogryphosis–palmoplantar keratoderma–periodontitis syndrome
  Hypotrichosis–acro-osteolysis–onychogryphosis–palmoplantar keratoderma–periodontitis syndrome is a cutaneous condition characterized by a prominent palmoplantar keratoderma....
  
   (HOPP syndrome)
• Hypotrichosis–lymphedema–telangiectasia syndrome
  Hypotrichosis–lymphedema–telangiectasia syndrome
  Hypotrichosis–lymphedema–telangiectasia syndrome is a congenital condition characterized by an autosomal dominant or autosomal recessive inheritance patternIt is associated with SOX18....
  
  
• Ichthyosis–brittle hair–impaired intelligence–decreased fertility–short stature syndrome (IBIDS syndrome, Sulfur-deficient brittle hair syndrome, Tay's syndrome, Trichothiodystrophy, Trichothiodystrophy with ichthyosis)
• Ichthyosis bullosa of Siemens
  Ichthyosis bullosa of Siemens
  Ichthyosis bullosa of Siemens is a rare skin disorder which is a type of familial, autosomal dominant ichthyosis. It is also known as bullous congenital ichthyosiform erythroderma of Siemens or ichthyosis exfoliativa...
  
   (Ichthyosis exfoliativa)
• Ichthyosis follicularis (Ichthyosis follicularis with alopecia and photophobia syndrome)
• Ichthyosis linearis circumflexa
  Ichthyosis linearis circumflexa
  Ichthyosis linearis circumflexa is a distinctive skin condition of generalized hyperkeratosis and polycyclic and serpiginous erythematous plaques with a characteristic, migratory, double-edged scale at the margins, and is the typical cutaneous manifestation of Netherton's syndrome....
  
  
• Ichthyosis prematurity syndrome
  Ichthyosis prematurity syndrome
  Ichthyosis prematurity syndrome is a cutaneous condition which has a known genetic abnormality associated with it.It is associated with SLC27A4....
  
  
• Ichthyosis vulgaris
  Ichthyosis vulgaris
  Ichthyosis vulgaris is a skin disorder causing dry, scaly skin. It is the most common form of ichthyosis, affecting around 1 in 250 people. For this reason it is known as common ichthyosis...
  
   (Autosomal dominant ichthyosis, Ichthyosis simplex)
• Neonatal ichthyosis–sclerosing cholangitis syndrome
  Neonatal ichthyosis–sclerosing cholangitis syndrome
  Neonatal ichthyosis–sclerosing cholangitis syndrome is a cutaneous condition caused by mutations in the Claudin 1 gene....
  
   (Ichthyosis–sclerosing cholangitis syndrome, NISCH syndrome)
• Incontinentia pigmenti achromians
  Incontinentia pigmenti achromians
  Incontinentia pigmenti achromians is a cutaneous condition characterized by various patterns of bilateral or unilateral hypopigmentation following the lines of Blaschko....
  
   (Hypomelanosis of Ito)
• Immune dysfunction–polyendocrinopathy–enteropathy–X-linked syndrome (IPEX syndrome)
• Jaffe–Campanacci syndrome
  Jaffe–Campanacci syndrome
  Jaffe–Campanacci syndrome is one of the disorders associated with café au lait macules . Presentations may include mental retardation, disseminated non-ossifying fibromas of the long bones and jaw, hypogonadism or cryptorchidism, or giant cell granulomas of the jaw.It was characterized in 1958 and...
  
  
• Johanson–Blizzard syndrome
• Johnson–McMillin syndrome
  Johnson–McMillin syndrome
  Johnson–McMillin syndrome is a neuroectodermal syndrome that consist of conductive hearing loss and microtia....
  
  
• Joubert syndrome
  Joubert syndrome
  Joubert syndrome is a rare genetic disorder that affects the cerebellum, an area of the brain that controls balance and coordination.-Diagnosis:...
  
  
• Junctional epidermolysis bullosa
  Junctional epidermolysis bullosa (medicine)
  Junctional epidermolysis bullosa is a skin condition characterized by blister formation within the lamina lucida of the basement membrane zone.Types include:Another form, cicatricial junctional epidermolysis bullosa, is not included in OMIM....
  
  
• Junctional epidermolysis bullosa gravis
  Junctional epidermolysis bullosa gravis
  Junctional epidermolysis bullosa gravis is the most lethal type of epidermolysis bullosa, a skin condition in which most patients do not survive infancy, characterized by blistering at birth with severe and clinically...
  
   (Epidermolysis bullosa letalis, Herlitz disease, Herlitz epidermolysis bullosa, Herlitz syndrome, Lethal junctional epidermolysis bullosa)
• Junctional epidermolysis bullosa with pyloric atresia
  Junctional epidermolysis bullosa with pyloric atresia
  Junctional epidermolysis bullosa with pyloric atresia is a rare autosomal recessive form of junctional epidermolysis bullosa that presents at birth with severe mucocutaneous fragility and gastric outlet obstruction....
  
  
• Kabuki syndrome
  Kabuki syndrome
  Kabuki syndrome, also previously known as Kabuki makeup syndrome, KMS or Niikawa–Kuroki Syndrome, is a pediatric congenital disorder of suspected genetic origin with multiple congenital anomalies and intellectual disabilities. It is very rare, affecting roughly one in every 32,000 individuals...
  
   (Kabuki makeup syndrome, Niikawa–Kuroki syndrome)
• Keratolytic winter erythema
  Keratolytic winter erythema
  Keratolytic Winter erythema , also known as erythrokeratolysis hiemalis, Oudtshoorn disease and Oudtshoorn skin, is a rare autosomal dominant skin disease of unknown etiology which causes erythema and keratolysis of the skin on the palms and soles. Onset, increased prominence and severity usually...
  
   (Erythrokeratolysis hiemalis, Oudtshoorn disease, Oudtshoorn skin)
• Keratosis follicularis spinulosa decalvans
  Keratosis follicularis spinulosa decalvans
  Keratosis follicularis spinulosa decalvans is a rare X-linked disorder described by Siemens in 1926, a disease that begins in infancy with keratosis pilaris localized on the face, then evolves to more diffuse involvement....
  
   (Siemens-1 syndrome)
• Keratosis linearis with ichthyosis congenital and sclerosing keratoderma syndrome
  Keratosis linearis with ichthyosis congenital and sclerosing keratoderma syndrome
  Keratosis linearis with ichthyosis congenital and sclerosing keratoderma syndrome is a cutaneous condition characterized by ichthyosis and keratoderma.It is associated with POMP....
  
   (KLICK syndrome)
• Keratosis pilaris atrophicans faciei
  Keratosis pilaris atrophicans faciei
  Keratosis pilaris atrophicans faciei begins in infancy as follicular papules with perifollicular erythema...
  
   (Folliculitis rubra, Keratosis pilaris rubra atrophicans faciei, Lichen pilare, Lichen pilaire ou xerodermie pilaire symmetrique de la face, Ulerythema ophryogenes, Xerodermi pilaire symmetrique de la face)
• Keratosis pilaris
  Keratosis pilaris
  Keratosis pilaris is a common, autosomal dominant, genetic follicular condition that is manifested by the appearance of rough bumps on the skin...
  
  
• Kindler syndrome
  Kindler syndrome
  Kindler syndrome is a rare congenital...
  
   (Acrokeratotic poikiloderma, Bullous acrokeratotic poikiloderma of Kindler and Weary, Congenital poikiloderma with blisters and keratoses, Congenital poikiloderma with bullae and progressive cutaneous atrophy, Hereditary acrokeratotic poikiloderma, Hyperkeratosis–hyperpigmentation syndrome, Weary–Kindler syndrome)
• Klinefelter syndrome
• Klippel–Feil syndrome
• Lamellar ichthyosis (Collodion baby)
• Legius syndrome
  Legius syndrome
  Legius syndrome is an autosomal dominant condition characterized by cafe au lait spots. It is often mistaken for Neurofibromatosis type I . It is caused by mutations in the SPRED1 gene. It is also known as Neurofibromatosis Type 1-like syndrome .The syndrome is named after Eric Legius,...
  
  
• Lelis syndrome
  Lelis syndrome
  Lelis syndrome it is a genetic disorder, a rare condition with dermatological and dental findings characterized by the association of ectodermal dysplasia with acanthosis nigricans...
  
  
• Lenz–Majewski syndrome
• Leschke syndrome
• Lethal acantholytic epidermolysis bullosa
  Lethal acantholytic epidermolysis bullosa
  Lethal acantholytic epidermolysis bullosa is a cutaneous condition characterized by generalized erosions at birth....
  
  
• Lhermitte–Duclos disease
• Linear and whorled nevoid hypermelanosis
  Linear and whorled nevoid hypermelanosis
  Linear and whorled nevoid hypermelanosis is a disorder of pigmentation that...
  
   (Linear nevoid hyperpigmentation, Progressive cribriform and zosteriform hyperpigmentation, Reticulate and zosteriform hyperpigmentation, Reticulate hyperpigmentation of Iijima and Naito and Uyeno, Zebra-like hyperpigmentation in whorls and streaks, Zebra-line hyperpigmentation)
• Linear Darier disease
  Linear Darier disease
  Linear Darier disease is a cutaneous condition identical to the generalized form of Darier's disease. "Acantholytic dyskeratotic epidermal nevus" is probably the same disorder....
  
   (Acantholytic dyskeratotic epidermal nevus)
• Linear porokeratosis
  Linear porokeratosis
  Linear porokeratosis is characterized clinically by basic skin lesions that are identical to those of classic porokeratosis Mibelli, including lichenoid papules, annular lesions, hyperkeratotic plaques with central atrophy, and the characteristic peripheral ridge....
  
  
• Localized epidermolysis bullosa simplex
  Localized epidermolysis bullosa simplex
  Localized epidermolysis bullosa simplex is a skin condition characterized by onset in childhood or later in life, and is the most common variant of epidermolysis bullosa simplex.- References :...
  
   (Weber–Cockayne syndrome, Weber–Cockayne variant of generalized epidermolysis bullosa simplex)
• Mandibuloacral dysplasia
  Mandibuloacral dysplasia
  Mandibuloacral dysplasia is a rare autosomal recessive syndrome characterized by mandibular hypoplasia, delayed cranial suture closure, dysplastic clavicals, abbreviated and club-shaped terminal phalanges, acroosteolysis, atrophy of the skin of the hands and feet, and typical facial changes.Types...
  
  
• Marinesco–Sjögren syndrome
  Marinesco–Sjögren syndrome
  -Presentation:The syndrome causes cerebellar ataxia , mental retardation, congenital cataracts in early childhood, muscle weakness, inability to chew food, thin brittle fingernails, and sparse hair.....
  
  
• McCune–Albright syndrome
• McCusick syndrome
  McCusick syndrome
  McCusick syndrome is characterized by short-limbed dwarfism and fine, sparse, hypoplastic, and dysmorphic hair....
  
  
• Metageria
• Microphthalmia–dermal aplasia–sclerocornea syndrome
  Microphthalmia–dermal aplasia–sclerocornea syndrome
  Microphthalmia–dermal aplasia–sclerocornea syndrome is a condition characterized by linear skin lesions.It can be associated with HCCS.-External links:*...
  
   (MIDAS syndrome)
• Mitis junctional epidermolysis bullosa
  Mitis junctional epidermolysis bullosa
  Mitis junctional epidermolysis bullosa is a skin condition characterized by scalp and nail lesions, also associated with periorificial nonhealing erosions. Mitis junctional epidermolysis bullosa is most commonly seem in children between the ages of 4 and 10 years old....
  
   (Nonlethal junctional epidermolysis bullosa)
• Mitochondrial myopathy–encephalopathy–lactic acidosis–stroke syndrome (MELAS syndrome)
• Multiple lentigines syndrome (Cardiocutaneous syndrome, Gorlin syndrome II, Lentiginosis profusa syndrome, LEOPARD syndrome, Progressive cardiomyopathic lentiginosis)
• Multiple pterygium syndrome
  Multiple pterygium syndrome
  Multiple pterygium syndrome is a cutaneous condition inherited in an autosomal dominant fashion....
  
  
• Multiple sulfatase deficiency
  Multiple sulfatase deficiency
  Multiple sulfatase deficiency is a very rare autosomal recessive lysosomal storage disease caused by a deficiency in multiple sulfatase enzymes...
  
   (Austin disease, Mucosulfatidosis)
• Naegeli–Franceschetti–Jadassohn syndrome (Chromatophore nevus of Naegeli)
• Netherton syndrome
  Netherton syndrome
  Netherton syndrome is a severe, autosomal recessive form of ichthyosis associated with mutations in the SPINK5 gene. It is named after E.W. Netherton.- Characteristics :...
  
  
• Neurofibromatosis type 1 (von Recklinghausen's disease)
• Neurofibromatosis type 3
  Neurofibromatosis type 3
  Neurofibromatosis type 3 resembles von Recklinghausen's disease, but also presents with cutaneous neurofibromas....
  
   (Neurofibromatosis mixed type)
• Neurofibromatosis type 4
  Neurofibromatosis type 4
  Neurofibromatosis type 4 resembles von Recklinghausen's disease, but also presents with cutaneous neurofibromas....
  
   (Neurofibromatosis variant type)
• Neutral lipid storage disease
  Neutral lipid storage disease
  Neutral lipid storage disease is an autosomal recessive disorder characterized by accumulation of triglycerides in the cytoplasm of leukocytes, muscle, liver, fibroblasts, and other tissues....
  
   (Dorfman–Chanarin syndrome)
• Nonbullous congenital ichthyosiform erythroderma (Congenital ichthyosiform erythroderma)
• Noonan syndrome
  Noonan syndrome
  Noonan Syndrome is a relatively common autosomal dominant congenital disorder considered to be a type of dwarfism, that affects both males and females equally. It used to be referred to as the male version of Turner's syndrome ; however, the genetic causes of Noonan syndrome and Turner syndrome...
  
  
• Oculocerebrocutaneous syndrome
  Oculocerebrocutaneous syndrome
  Oculocerebrocutaneous syndrome is a condition characterized by orbital cysts, microphthalmia, porencephaly, agenesis of the corpus callosum, and facial skin tags....
  
   (Delleman–Oorthuys syndrome)
• Oculodentodigital dysplasia
  Oculodentodigital dysplasia
  Oculodentodigital syndrome is an extremely rare genetic condition that typically results in small eyes, underdeveloped teeth, and syndactyly and malformation of the fourth and fifth fingers. It has also been called oculo-dento-digital syndrome, oculodentodigital dysplasia , and oculodentoosseous...
  
  
• Odonto–Tricho–Ungual–Digital–Palmar syndrome
• Oliver–McFarlane syndrome
  Oliver–McFarlane syndrome
  Oliver–McFarlane syndrome is a condition characterized by hypertrichosis of the eyebrows and eyelashes....
  
  
• Pachydermoperiostosis
  Pachydermoperiostosis
  Pachydermoperiostosis or Primary hypertrophic osteoathropathy is a rare genetic disorder that affects both bones and skin. Other names are idiopathic hypertrophic osteoarthropathy or Touraine-Solente-Gole syndrome...
  
   (Idiopathic hypertrophic osteoathorpathy, Touraine–Solente–Gole syndrome)
• Peeling skin syndrome
  Peeling skin syndrome
  Peeling skin syndrome is an autosomal recessive disorder characterized by lifelong peeling of the stratum corneum, and may be associated with pruritus, short stature, and easily removed anagen hair.The...
  
   (Acral peeling skin syndrome, Continual peeling skin syndrome, Familial continual skin peeling, Idiopathic deciduous skin, Keratolysis exfoliativa congenita)
• Pfeiffer syndrome
  Pfeiffer syndrome
  Pfeiffer syndrome is a rare genetic disorder characterized by the premature fusion of certain bones of the skull , which prevents further growth of the skull and affects the shape of the head and face...
  
  
• Photosensitivity–ichthyosis–brittle sulfur-deficient hair–impaired intelligence–decreased fertility–short stature syndrome (PIBI(D)S syndrome)
• Pityriasis rotunda
  Pityriasis rotunda
  Pityriasis rotunda is a skin condition that manifests as a perfectly circular, scaly patches on the torso and proximal portions of the extremities....
  
   (Pityriasis circinata, Tinea circinata)
• Plaque-type porokeratosis
  Plaque-type porokeratosis
  Plaque-type porokeratosis is characterized by skin lesions that start as small, brownish papules that slowly enlarge to form irregular, annular, hyperkeratotic or verrucous plaques....
  
   (Classic porokeratosis, Porokeratosis of Mibelli)
• Polyneuropathy–organomegaly–endocrinopathy–monoclonal gammopathy–skin changes syndrome (Crow–Fukase syndrome, POEMS syndrome)
• Polyostotic fibrous dysplasia
  Polyostotic fibrous dysplasia
  Polyostotic fibrous dysplasia is a form of fibrous dysplasia affecting more than one bone.The McCune-Albright syndrome includes polyostotic fibrous dysplasia as part of its presentation....
  
   (Albright's disease)
• Popliteal pterygium syndrome
  Popliteal pterygium syndrome
  Popliteal pterygium syndrome is an inherited condition affecting the face, limbs, and genitalia. The syndrome goes by a number of names including the popliteal web syndrome and, more inclusively, the facio-genito-popliteal syndrome...
  
  
• Porokeratosis
  Porokeratosis
  Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer....
  
  
• Porokeratosis palmaris et plantaris disseminata
  Porokeratosis palmaris et plantaris disseminata
  Porokeratosis palmaris et plantaris disseminata is characterized by skin lesions that are superficial, small, relatively uniform, and demarcated by a distinct peripheral ridge of no more than 1mm in height....
  
  
• Prader–Willi syndrome
• Progeria
  Progeria
  Progeria is an extremely rare genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. The word progeria comes from the Greek words "pro" , meaning "before", and "géras" , meaning "old age"...
  
   (Hutchinson–Gilford progeria syndrome, Hutchinson–Gilford syndrome, Progeria syndrome)
• Progressive osseous heteroplasia
  Progressive osseous heteroplasia
  Progressive osseous heteroplasia is a cutaneous condition characterized by cutaneous or subcutaneous ossification.It is associated with GNAS.- See also :* Punctate porokeratosis* List of cutaneous conditions* Pseudopseudohypoparathyroidism...
  
  
• Progressive symmetric erythrokeratodermia
  Progressive symmetric erythrokeratodermia
  Progressive symmetric erythrokeratodermia is a rare, autosomal dominant skin condition that manifests soon after birth with erythematous, hyperkeratotic plaques that are symmetrically distributed on the extremities, buttocks, and face, but sparing the trunk...
  
   (Erythrokeratodermia progressiva symmetrica)
• Proteus syndrome
  Proteus syndrome
  Proteus syndrome, also known as Wiedemann's syndrome , is a congenital disorder that causes skin overgrowth and atypical bone development, often accompanied by tumors over half the body....
  
  
• Proteus-like syndrome
  Proteus-like syndrome
  Proteus-like syndrome is a condition similar to Proteus syndrome, but with an uncertain etiology.-External links:*...
  
  
• Punctate porokeratosis
  Punctate porokeratosis
  Not to be confused with Spiny keratoderma ...
  
  
• Rapp–Hodgkin syndrome (Rapp–Hodgkin ectodermal dysplasia syndrome)
• Recessive dystrophic epidermolysis bullosa
  Recessive dystrophic epidermolysis bullosa
  Recessive dystrophic epidermolysis bullosa is a skin condition resulting from mutations in the gene encoding type VII collagen, COL7A1, characterized by debilitating oral lesions that produce pain, scarring, and microstomia.It is named for François Henri Hallopeau and Hermann Werner...
  
   (Hallopeau–Siemens variant of epidermolysis bullosa, Hallopeau–Siemens disease)
• Refsum's disease
  Refsum's disease
  Refsum disease, also known as classic or adult Refsum disease, heredopathia atactica polyneuritiformis, phytanic acid oxidase deficiency and phytanic acid storage disease, is an autosomal recessive neurological disease that results from the over-accumulation of phytanic acid in cells and tissues...
  
   (Heredopathia atactica polyneuritiformis, Phytanic acid storage disease)
• Relapsing linear acantholytic dermatosis
  Relapsing linear acantholytic dermatosis
  Relapsing linear acantholytic dermatosis is a cutaneous condition characterized by relapsing linear erosions and crusting, histologically identical to Hailey–Hailey disease....
  
  
• Restrictive dermopathy
  Restrictive dermopathy
  Restrictive dermopathy is a rare, lethal autosomal recessive skin condition characterized by abnormal facies, tight skin, sparse or absent eyelashes, and secondary joint changes.- Mechanism :...
  
  
• Rhizomelic chondrodysplasia punctata
  Rhizomelic chondrodysplasia punctata
  Rhizomelic chondrodysplasia punctata is a rare, developmental brain disorder characterized by systemic shortening of the proximal bones , seizures, recurrent respiratory tract infections, and congential cataracts.-Types:...
  
   (Autosomal recessive chondrodysplasia punctata type 1, Chondrodystrophia calcificans punctata, Peroxisomal biogenesis disorder complementation group 11)
• Rombo syndrome
  Rombo syndrome
  Rombo syndrome is a very rare genetic disorder characterized mainly by atrophoderma vermiculatum of the face, multiple milia, telangiectases, acral erythema,peripheral vasodilation with cyanosis and a propensity to develop basal cell carcinomas....
  
  
• Rothmund–Thomson syndrome (Poikiloderma congenitale)
• Rud syndrome
  Rud syndrome
  Rud syndrome is a poorly characterized disorder, probably of recessive inheritance, that includes epilepsy, mental retardation, infantilism, congenital ichthyosis, and retinitis pigmentosa....
  
  
• Say syndrome
  Say syndrome
  Say syndrome is a condition characterized by bilateral acromial dimples....
  
  
• Scalp–ear–nipple syndrome
  Scalp–ear–nipple syndrome
  Scalp–ear–nipple syndrome is a condition associated with aplasia cutis congenita....
  
   (Finlay–Marks syndrome)
• Schindler disease
  Schindler disease
  Schindler disease, also known as Kanzaki disease and Alpha-N-acetylgalactosaminidase deficiency is a rare congenital metabolic disorder in humans...
  
   (Kanzaki disease, Alpha-N-acetylgalactosaminidase deficiency)
• Schinzel–Giedion syndrome
• Scleroatrophic syndrome of Huriez
  Scleroatrophic syndrome of Huriez
  Scleroatrophic syndrome of Huriez is an autosomal dominant keratoderma with sclerodactyly present at birth with a diffuse symmetric keratoderma of the palms and soles.An association...
  
   (Huriez syndrome, Palmoplantar keratoderma with scleroatrophy, Palmoplantar keratoderma with sclerodactyly, Scleroatrophic and keratotic dermatosis of the limbs, Sclerotylosis)
• Segmental neurofibromatosis
• Senter syndrome
  Senter syndrome
  Senter syndrome is a cutaneous condition characterized by similar skin changes and congenital hearing impairment to keratitis–ichthyosis–deafness syndrome, but is associated with glycogen storage leading to hepatomegaly, hepatic cirrhosis, growth failure and mental retardation....
  
   (Desmons' syndrome)
• Shabbir syndrome
  Shabbir syndrome
  Shabbir syndrome is a cutaneous condition inherited in an autosomal recessive fashion.It was characterized by Shabbir in 1986.It may be associated with LAMA3....
  
   (Laryngo–onycho–cutaneous syndrome)
• Silver–Russell syndrome
  Silver–Russell syndrome
  Silver-Russell dwarfism, also called Silver-Russell syndrome or Russell-Silver syndrome is a growth disorder occurring in approximately 1/50,000 to 1/100,000 births. In the United States it is usually referred to as Russell-Silver Syndrome, and Silver-Russell Syndrome elsewhere...
  
  
• Sjögren–Larsson syndrome 
  
• Skin fragility syndrome
  Skin fragility syndrome
  Skin fragility syndrome is a cutaneous condition characterized by trauma-induced blisters and erosions.It is associated with PKP1....
  
   (Plakophilin 1 deficiency)
• Supernumerary nipples–uropathies–Becker's nevus syndrome
  Supernumerary nipples–uropathies–Becker's nevus syndrome
  Supernumerary nipples–uropathies–Becker's nevus syndrome is a cutaneous condition that may be associated with genitourinary tract abnormalities....
  
   (SNUB syndrome)
• Terminal osseous dysplasia with pigmentary defects
  Terminal osseous dysplasia with pigmentary defects
  Terminal osseous dysplasia with pigmentary defects is a cutaneous condition characterized by hyperpigmented, atrophic facial macules.It has been associated with FLNA.- See also :* Corneodermatosseous syndrome* Osseous choristoma of the tongue...
  
  
• Tooth and nail syndrome
  Tooth and nail syndrome
  Tooth and nail syndrome is a rare disorder, first described in 1965, characterized by nails that are thin, small, and friable, and which may show koilonychia at birth....
  
   (Hypodontia with nail dysgenesis, Witkop syndrome)
• Townes–Brocks syndrome
• Transient bullous dermolysis of the newborn
  Transient bullous dermolysis of the newborn
  Transient bullous dermolysis of the newborn is a skin condition that presents in newborns. It is characterized by blister formation secondary to even mild trauma.It is associated with COL7A1....
  
  
• Treacher Collins syndrome
  Treacher Collins syndrome
  Treacher Collins syndrome , also known as Treacher Collins–Franceschetti syndrome, or mandibulofacial dysostosis is a rare autosomal dominant congenital disorder characterized by craniofacial deformities, such as absent cheekbones. Treacher Collins syndrome is found in about 1 in 10,000 births, ....
  
   (Treacher Collins–Franceschetti syndrome)
• Tricho–rhino–phalangeal syndrome
• Tuberous sclerosis
  Tuberous sclerosis
  Tuberous sclerosis or tuberous sclerosis complex is a rare multi-system genetic disease that causes non-malignant tumors to grow in the brain and on other vital organs such as the kidneys, heart, eyes, lungs, and skin. A combination of symptoms may include seizures, developmental delay, behavioral...
  
   (Bourneville disease, Epiloia)
• Turner syndrome
  Turner syndrome
  Turner syndrome or Ullrich-Turner syndrome encompasses several conditions in human females, of which monosomy X is most common. It is a chromosomal abnormality in which all or part of one of the sex chromosomes is absent...
  
  
• Ulnar–mammary syndrome
  Ulnar–mammary syndrome
  Ulnar–mammary syndrome is a cutaneous condition characterized by nipple and breast hypoplasia or aplasia.It has been associated with TBX3.- References :...
  
  
• Van Der Woude syndrome
  Van der Woude syndrome
  Van Der Woude syndrome is a genetic disorder and congenital malformation. People with VDWS have cleft lip with or without cleft palate, pits or mucous cysts on the lower lip, hypodontia, a hypernasal voice, cleft or bifid uvula, syngnathia, narrow high arched palate, and ankyloglossia...
  
  
• Von Hippel–Lindau syndrome
• Watson syndrome
  Watson syndrome
  Watson syndrome is an autosomal recessive condition characterized by Lisch nodules, axillary/inguinal freckling, and neurofibromas.Watson syndrome may be allelic to NF1, the same gene associated with Neurofibromatosis type 1.- References :...
  
  
• Werner syndrome
  Werner syndrome
  Werner syndrome is a very rare, autosomal recessive disorder characterized by the appearance of premature aging....
  
   (Adult progeria)
• Westerhof syndrome
  Westerhof syndrome
  Westerhof syndrome is a cutaneous condition inherited in an autosomal dominant fashion, characterized by congenital hypopigmented macules....
  
  
• Whistling syndrome (Cranio-carpo-tarsal syndrome, Distal arthrogryposis type 2, Freeman–Sheldon syndrome, Windmill–Vane–Hand syndrome)
• Wilson–Turner syndrome
  Wilson–Turner syndrome
  Wilson–Turner syndrome is a congenital condition characterized by mental retardation and associated with childhood-onset obesity.A locus has been described, but no gene has been identified....
  
  
• Wolf–Hirschhorn syndrome (4p- syndrome)
• X-linked ichthyosis
  X-linked ichthyosis
  X-linked ichthyosis is a skin condition caused by the hereditary deficiency of the steroid sulfatase enzyme that affects 1 in 2000 to 1 in 6000 males. XLI manifests with dry, scaly skin and is due to deletions or mutations in the STS gene...
  
   (Steroid sulfatase deficiency, X-linked recessive ichthyosis)
• X-linked recessive chondrodysplasia punctata
  X-linked recessive chondrodysplasia punctata
  X-linked recessive chondrodysplasia punctata is a type of chondrodysplasia punctata that can involve the skin, hair, and cause short stature with skeletal abnormalities, cataracts, and deafness.It has been associated with arylsulfatase E....
  
  
• Xeroderma pigmentosum
  Xeroderma pigmentosum
  Xeroderma pigmentosum, or XP, is an autosomal recessive genetic disorder of DNA repair in which the ability to repair damage caused by ultraviolet light is deficient. In extreme cases, all exposure to sunlight must be forbidden, no matter how small. Multiple basal cell carcinomas and other skin...
  
   (Cockayne syndrome complex)
• XXYY genotype
• Zimmermann–Laband syndrome

Infection-related

Infection-related cutaneous conditions may be caused by bacteria

Bacteria

Bacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...

, fungi, yeast

Yeast

Yeasts are eukaryotic micro-organisms classified in the kingdom Fungi, with 1,500 species currently described estimated to be only 1% of all fungal species. Most reproduce asexually by mitosis, and many do so by an asymmetric division process called budding...

, virus

Virus

A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

es, and/or parasites

Parasitism

Parasitism is a type of symbiotic relationship between organisms of different species where one organism, the parasite, benefits at the expense of the other, the host. Traditionally parasite referred to organisms with lifestages that needed more than one host . These are now called macroparasites...

.

Bacterium-related

Bacterium-related cutaneous conditions often have distinct morphologic

Morphology (biology)

In biology, morphology is a branch of bioscience dealing with the study of the form and structure of organisms and their specific structural features....

 characteristics that may be an indication of a generalized systemic process or simply an isolated superficial infection.

• Aeromonas infection
  Aeromonas infection
  Aeromonas infections may cause skin infections manifesting as cellulitis, pustules, and furuncles....
  
  
• African tick bite fever
  African tick bite fever
  African tick bite fever is a condition that is often associated with a rash characterized by scant lesions, often macular and/or vesicular.It is caused by Rickettsia africae.- See also :* Flea-borne spotted fever* Rocky Mountain spotted fever...
  
  
• American tick bite fever
  American tick bite fever
  American tick bite fever is a condition that may be characterized by a rash of maculopapules.- See also :* Rickettsia aeschlimannii infection* Flea-borne spotted fever* List of cutaneous conditions...
  
   (Rickettsia parkeri infection)
• Arcanobacterium haemolyticum infection
  Arcanobacterium haemolyticum infection
  Arcanobacterium haemolyticum infection can causes an acute pharyngitis, and may causes an exanthem characterized by an erythematous morbilliform or scarlatiniform eruption involving the trunk and extremities....
  
  
• Bacillary angiomatosis
  Bacillary angiomatosis
  Bacillary angiomatosis is a form of angiomatosis associated with bacteria of the Bartonella genus.-Causes:It is caused by either Bartonella henselae or Bartonella quintana....
  
  
• Bejel
  Bejel
  Bejel, or endemic syphilis, is a chronic skin and tissue disease caused by infection by a subspecies of the spirochete Treponema pallidum....
  
   (Endemic syphilis)
• Blastomycosis-like pyoderma
  Blastomycosis-like pyoderma
  Blastomycosis-like pyoderma is a cutaneous condition characterized by larger verrucous plaques with elevated borders and multiple pustules occurring....
  
   (Pyoderma vegetans)
• Blistering distal dactylitis
  Blistering distal dactylitis
  Blistering distal dactylitis is a cutaneous condition characterized by tense superficial bullae occurring on a tender erythematous base over the volar fat pad of the phalanx of a finger or thumb....
  
  
• Botryomycosis
  Botryomycosis
  Botryomycosis; also known as bacterial pseudomycosis is a rare chronic granulomatous bacterial infection that affects the skin, and sometimes the viscera.Botryomycosis has been known to affect humans, horses, cattle, swine, dogs and cats.-History:...
  
  
• Brill–Zinsser disease
  Brill–Zinsser disease
  Brill–Zinsser disease is a delayed relapse of epidemic typhus, caused by Rickettsia prowazekii. After a patient contracts epidemic typhus from the bite of an infected louse , the rickettsia can remain latent and reactivate months or years later, with symptoms similar to or even identical to the...
  
  
• Brucellosis
  Brucellosis
  Brucellosis, also called Bang's disease, Crimean fever, Gibraltar fever, Malta fever, Maltese fever, Mediterranean fever, rock fever, or undulant fever, is a highly contagious zoonosis caused by ingestion of unsterilized milk or meat from infected animals or close contact with their secretions...
  
   (Bang's disease, Malta fever, Undulant fever)
• Bullous impetigo
  Bullous impetigo
  Bullous Impetigo is a cutaneous condition that characteristically occurs in the newborn, and is caused by a bacterial infection, presenting with bullae....
  
  
• Cat scratch disease
  Cat scratch disease
  Cat scratch disease is a usually benign infectious disease caused by the intracellular bacterium Bartonella. It is most commonly found in children following a scratch or bite from a cat by about one to two weeks...
  
   (Cat scratch fever, English–Wear infection, Inoculation lymphoreticulosis, Subacute regional lymphadenitis)
• Cellulitis
  Cellulitis
  Cellulitis is a diffuse inflammation of connective tissue with severe inflammation of dermal and subcutaneous layers of the skin. Cellulitis can be caused by normal skin flora or by exogenous bacteria, and often occurs where the skin has previously been broken: cracks in the skin, cuts, blisters,...
  
   
  
• Chancre
  Chancre
  A chancre is a painless ulceration formed during the primary stage of syphilis. This infectious lesion forms approximately 21 days after the initial exposure to Treponema pallidum, the gram-negative spirochaete bacterium yielding syphilis. Chancres transmit the sexually transmissible disease of...
  
  
• Chancroid
  Chancroid
  Chancroid is a sexually transmitted infection characterized by painful sores on the genitalia...
  
   (Soft chancre, Ulcus molle)
• Chlamydial infection
• Chronic lymphangitis
  Chronic lymphangitis
  Chronic lymphangitis is a cutaneous condition that is the end result of recurrent bouts of acute bacterial lymphangitis....
  
  
• Chronic recurrent erysipelas
  Chronic recurrent erysipelas
  Chronic recurrent erysipelas is a cutaneous condition with several predisposing factors including alcoholism, diabetes, and tinea pedis.If there is a delay in getting antibiotics to fight erysepalis immediately, xylatol and erythratol sugar can act as an antibiotic to kill the strep as it will feed...
  
  
• Chronic undermining burrowing ulcers
  Chronic undermining burrowing ulcers
  Chronic undermining burrowing ulcers is a cutaneous condition that is a postoperative, progressive bacterial gangrene....
  
   (Meleney gangrene)
• Chromobacteriosis infection
  Chromobacteriosis infection
  Chromobacteriosis infections are a cutaneous condition caused by chromobacteria characterized by fluctuating abscesses....
  
  
• Condylomata lata
  Condylomata lata
  Condylomata lata or condyloma latum, is a cutaneous condition characterized by wart like lesions on the genitals. They are generally symptoms of the secondary phase of syphilis, caused by the spirochete, Treponema pallidum....
  
  
• Cutaneous actinomycosis
  Cutaneous actinomycosis
  Cutaneous actinomycosis is a chronic disease that affects the deep subcutaneous tissue of the skin. Caused by an anaerobic, Gram-positive, filamentous type of bacteria in the genus Actinomyces, invasion of the soft tissue leads to the formation of abnormal channels leading to the skin surface that...
  
  
• Cutaneous anthrax infection
• Cutaneous diphtheria infection
  Cutaneous diphtheria infection
  Cutaneous diphtheria is an infection of the skin by Corynebacterium diphtheriae.It is also known as "desert sore"....
  
  
• Cutaneous group B streptococcal infection
  Cutaneous group B streptococcal infection
  Cutaneous group B streptococcal infection may result in orbital cellulitis or facial erysipelas in neonates....
  
  
• Cutaneous Pasteurella hemolytica infection
  Cutaneous Pasteurella hemolytica infection
  Cutaneous Pasteurella hemolytica infections may occur in patients with skin inhury and exposure Pasteurella hemolytica....
  
  
• Cutaneous Streptococcus iniae infection
  Cutaneous Streptococcus iniae infection
  Cutaneous Streptococcus iniae infections cause a cellulitis of the hands, usually after a person handles tilapia, as this bacteria is a fish pathogen....
  
  
• Dermatitis gangrenosa
  Dermatitis gangrenosa
  Dermatitis gangrenosa is a cutaneous condition caused by infection by Clostridium resulting in a necrosis and sloughing of the skin....
  
   (Gangrene of the skin)
• Desert sore (Barcoo rot, Diphtheric desert sore, Septic sore, Veldt sore)
• Ecthyma
  Ecthyma
  -Definition and Introduction:Ecthyma is an ulcerative pyoderma of the skin caused by bacteria such as Streptococcus pyogenes, Pseudomonas and Staphylococcus aureus. Because ecthyma extends into the dermis, it is often referred to as a deeper form of impetigo....
  
  
• Ecthyma gangrenosum
  Ecthyma gangrenosum
  Ecthyma gangrenosum is an infection of the skin typically caused by Pseudomonas aeruginosa. It presents as a round or oval lesion, 1 cm to 15 cm in diameter, with a halo of erythema. A necrotic center is usually present with a surrounding erythematous edge, representing where the organism invaded...
  
  
• Ehrlichiosis ewingii infection
• Elephantiasis nostras
  Elephantiasis nostras
  Elephantiasis nostras is a cutaneous condition, a final hypertrophic fibrosis following longstanding chronic lymphangitis.- Symptoms :The disease usually affects the lower legs or scrotum. The swelling is accompanied by rough nodules or wart-like plaques on the skin...
  
  
• Endemic typhus (Murine typhus)
• Epidemic typhus (Epidemic louse-borne typhus)
• Erysipelas
  Erysipelas
  Erysipelas is an acute streptococcus bacterial infection of the deep epidermis with lymphatic spread.-Risk factors:...
  
   (Ignis sacer, Saint Anthony's fire)
• Erysipeloid of Rosenbach
  Erysipeloid of Rosenbach
  Erysipeloid of Rosenbach is a cutaneous condition most frequently characterized by a purplish marginated swelling on the hands.-Discovery:The eponym Rosenbach’s disease is in reference to the milder type of the condition and is named after Friedrich Julius Rosenbach. Klauder’s syndrome I is a...
  
  
• Erythema marginatum
  Erythema marginatum
  Erythema marginatum is described as the presence of pink rings on the trunk and inner surfaces of the limbs which come and go for as long as several months. It is found primarily on extensor surfaces....
  
  
• Erythrasma
  Erythrasma
  Erythrasma is a skin disease that causes brown, scaly skin patches. It is caused by the gram positive bacterium Corynebacterium minutissimum.It is prevalent among diabetics, the obese, and in warm climates and is worsened by wearing occlusive clothing....
  
  
• External otitis (Otitis externa, Swimmer's ear)
• Flea-borne spotted fever
  Flea-borne spotted fever
  Flea-borne spotted fever is a condition characterized by a rash of maculopapules or furuncles.It is caused by Rickettsia felis.- See also :* American tick bite fever* Japanese spotted fever* List of cutaneous conditions...
  
  
• Flinders Island spotted fever
  Flinders Island spotted fever
  Flinders Island spotted fever is a condition characterized by a rash in approximately 85% of cases.It is associated with Rickettsia honei.- See also :* Japanese spotted fever* North Asian tick typhus* List of cutaneous conditions* Flinders Island...
  
  
• Flying squirrel typhus
  Flying squirrel typhus
  Flying squirrel typhus is a condition characterized by a rash of early macules, and, later, maculopapules.The flying squirrel Glaucomys volans can transmit epidemic typhus....
  
  
• Folliculitis
  Folliculitis
  Folliculitis is the inflammation of one or more hair follicles. The condition may occur anywhere on the skin with the exception of the palms of the hands and soles of the feet.- Causes :...
  
  
• Fournier gangrene
  Fournier gangrene
  Fournier's gangrene is a type of necrotizing infection or gangrene usually affecting the perineum.It was first described by Baurienne in 1764 and is named after a French venereologist, Jean-Alfred Fournier following five cases he presented in clinical lectures in 1883.-Cause:In the majority of...
  
   (Fournier gangrene of the penis or scrotum)
• Furunculosis (Boil)
• Gas gangrene
  Gas gangrene
  Gas gangrene is a bacterial infection that produces gas tissues in gangrene. It is a deadly form of gangrene usually caused by Clostridium perfringens bacteria. It is a medical emergency....
  
   (Clostridial myonecrosis, Myonecrosis)
• Glanders
  Glanders
  Glanders is an infectious disease that occurs primarily in horses, mules, and donkeys. It can be contracted by other animals such as dogs, cats and goats...
  
   (Equinia, Farcy, Malleus)
• Gonococcemia
  Gonococcemia
  Gonococcemia is a condition characterized by a hemorrhagic vesiculopustular eruption, bouts of fever, and arthralgia or actual arthritis of one or several joints....
  
   (Arthritis–dermatosis syndrome, Disseminated gonococcal infection)
• Gonorrhea
  Gonorrhea
  Gonorrhea is a common sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. The usual symptoms in men are burning with urination and penile discharge. Women, on the other hand, are asymptomatic half the time or have vaginal discharge and pelvic pain...
  
   (Clap)
• Gram-negative folliculitis
  Gram-negative folliculitis
  Gram-negative folliculitis occurs in patients who have had moderately inflammatory acne for long periods and have been treated with long-term antibiotics, mainly tetracyclines, a disease in which cultures of lesions usually reveals a species of Klebsiella, Escherichia coli, Enterobacter, or, from...
  
  
• Gram-negative toe web infection
  Gram-negative toe web infection
  Gram-negative toe web infection is a cutaneous condition that often begins with dermatophytosis....
  
  
• Granuloma inguinale (Donovanosis, Granuloma genitoinguinale, Granuloma inguinale tropicum, Granuloma venereum, Granuloma venereum genitoinguinale, Lupoid form of groin ulceration, Serpiginous ulceration of the groin, Ulcerating granuloma of the pudendum, Ulcerating sclerosing granuloma)
• Green nail syndrome
  Green nail syndrome
  Green nail syndrome occurs as a result of an infection with Pseudomonas aeruginosa, and may also occur as transverse green stripes that are ascribed to intermittent episodes of infection....
  
  
• Group JK corynebacterium sepsis
  Group JK corynebacterium sepsis
  Group JK corynebacterium sepsis is a form of sepsis which occurs when the bacterium Corynebacterium jeikeium colonizes the skin of healthy individuals and gains access to a person's blood stream....
  
  
• Haemophilus influenzae cellulitis
  Haemophilus influenzae cellulitis
  Haemophilus influenzae cellulitis is a cutaneous condition characterized by a distinctive bluish or purplish-red cellulitis of the face.- References :...
  
  
• Helicobacter cellulitis
  Helicobacter cellulitis
  Helicobacter cellulitis is a cutaneous condition caused by Helicobacter cinaedi....
  
  
• Hospital furunculosis
  Hospital furunculosis
  Hospital furunculosis is a cutaneous condition that can be epidemic in the hospital setting, characterized histopathologically by a deep abscess with both lymphocytes and neutrophils....
  
  
• Hot tub folliculitis
  Hot tub folliculitis
  Hot tub folliculitis is a common type of folliculitis, a condition which causes inflammation of the hair follicle....
  
   (Pseudomonas aeruginosa folliculitis)
• Human granulocytotropic anaplasmosis
• Human monocytotropic ehrlichiosis
• Impetigo contagiosa
• Japanese spotted fever
  Japanese spotted fever
  Japanese spotted fever is a condition characterized by a rash that has early macules, and later, in some patients, petechiae.It is caused by Rickettsia japonica.- See also :* Flea-borne spotted fever...
  
  
• Leptospirosis
  Leptospirosis
  Leptospirosis is caused by infection with bacteria of the genus Leptospira, and affects humans as well as other mammals, birds, amphibians, and reptiles.The...
  
   (Fort Bragg fever, Pretibial fever, Weil's disease)
• Listeriosis
• Ludwig's angina
  Ludwig's angina
  Ludwig's angina, otherwise known as angina ludovici, is a serious, potentially life-threatening cellulitis, or connective tissue infection, of the floor of the mouth, usually occurring in adults with concomitant dental infections. It is named after the German physician, Wilhelm Friedrich von Ludwig...
  
  
• Lupoid sycosis
  Lupoid sycosis
  Lupoid sycosis is a cutaneous condition that is characterized by a scarring form of deep folliculitis, typically affecting the beard area....
  
  
• Lyme disease
  Lyme disease
  Lyme disease, or Lyme borreliosis, is an emerging infectious disease caused by at least three species of bacteria belonging to the genus Borrelia. Borrelia burgdorferi sensu stricto is the main cause of Lyme disease in the United States, whereas Borrelia afzelii and Borrelia garinii cause most...
  
   (Afzelius' disease, Lyme borreliosis)
• Lymphogranuloma venereum
  Lymphogranuloma venereum
  Lymphogranuloma venereum is a sexually transmitted disease caused by the invasive serovars L1, L2, L2a or L3 of Chlamydia trachomatis....
  
   (Climatic bubo, Durand–Nicolas–Favre disease, Lymphogranuloma inguinale, Poradenitis inguinale, Strumous bubo)
• Malakoplakia
  Malakoplakia
  Malakoplakia is a rare inflammatory condition which makes its presence known as a papule, plaque or ulceration that usually affects the genitourinary tract. However, it may also be associated with other bodily organs. It was initially described in the early 1900s as soft yellowish plaques found on...
  
   (Malacoplakia)
• Mediterranean spotted fever (Boutonneuse fever)
• Melioidosis
  Melioidosis
  Melioidosis is an infectious disease caused by a Gram-negative bacterium, Burkholderia pseudomallei, found in soil and water. It is of public health importance in endemic areas, particularly in Thailand and northern Australia. It exists in acute and chronic forms. Symptoms may include pain in...
  
   (Whitmore's disease)
• Meningococcemia
  Meningococcemia
  Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis . It carries a high mortality rate if untreated. While best known as a cause of meningitis, widespread blood infection is more damaging and dangerous...
  
  
• Missouri Lyme disease
  Missouri Lyme disease
  Missouri Lyme disease is a cutaneous conditions. The cause of ‘Missouri Lyme disease’ has been a source of controversy. True Lyme disease probably occurs in Missouri and other southern states, although Lyme disease-like illnesses not related to Borrelia burgdorferi also occur. Strains of B....
  
  
• Mycoplasma infection
• Necrotizing fasciitis
  Necrotizing fasciitis
  Necrotizing fasciitis , commonly known as flesh-eating disease or Flesh-eating bacteria syndrome, is a rare infection of the deeper layers of skin and subcutaneous tissues, easily spreading across the fascial plane within the subcutaneous tissue.Necrotizing fasciitis is a quickly progressing and...
  
   (Flesh-eating bacteria syndrome)
• Neonatal toxic shock-like exanthematous disease
  Neonatal toxic shock-like exanthematous disease
  Neonatal toxic shock-like exanthematous disease is a cutaneous condition characterized by a generalized diffuse macular erythema or morbilliform eruption with confluence....
  
  
• Nocardiosis
  Nocardiosis
  Nocardiosis is an infectious disease affecting either the lungs or the whole body . It is due to infection by bacterium of the genus Nocardia, most commonly Nocardia asteroides or Nocardia brasiliensis.It is most common in men, especially those with a compromised immune system...
  
  
• Noma neonatorum
  Noma neonatorum
  Noma neonatorum is a cutaneous condition, a manifestation of infection, usually Pseudomonas aeruginosa septicemia, and has been reported almost exclusively in developing countries....
  
  
• North Asian tick typhus
  North Asian tick typhus
  North Asian tick typhus , also known as Siberian tick typhus, is a condition characterized by a maculopapular rash.It is associated with Rickettsia sibirica.- See also :* Flinders Island spotted fever...
  
  
• Ophthalmia neonatorum
  Ophthalmia neonatorum
  Neonatal conjunctivitis, also known as ophthalmia neonatorum, is a form of bacterial conjunctivitis contracted by newborns during delivery. The baby's eyes are contaminated during passage through the birth canal from a mother infected with either Neisseria gonorrhoeae or Chlamydia trachomatis....
  
   
• Oroya fever (Carrion's disease)
• Pasteurellosis
  Pasteurellosis
  Pasteurellosis is an infection with a species of the bacteria genus Pasteurella, which is found in humans and animals.Pasteurella multocida is carried in mouth and respiratory tract of several animals, notably cats. It is a small Gram negative bacillus with bipolar staining by Wayson stain...
  
  
• Perianal cellulitis
  Perianal cellulitis
  Perianal cellulitis is a cutaneous condition that presents as sharply demarcated, bright, perianal erythema extending 2–3 cm around the anal verge....
  
   (Perineal dermatitis, Streptococcal perianal disease)
• Periapical abscess
  Periapical abscess
  A periapical abscess is the result of a chronic, localized infection located at the tip, or apex, of the root of a tooth.To achieve resolution, endodontic therapy must be performed to debride the root canal or canals and remove pathogens....
  
  
• Pinta
  Pinta (disease)
  Pinta is a human skin disease endemic to Mexico, Central America, and South America. It is caused by infection with a spirochete, Treponema pallidum carateum, which is morphologically and serologically indistinguishable from the organism that causes syphilis.-Presentation:Pinta is thought to be...
  
  
• Pitted keratolysis
  Pitted keratolysis
  Pitted keratolysis is a non-contagious skin infection that can be caused by wearing tight or restricting footwear and excessive sweating. The infection is characterized by craterlike pits on the surface of the feet and toes, particularly weight bearing areas...
  
   (Keratolysis plantare sulcatum, Keratoma plantare sulcatum, Ringed keratolysis)
• Plague
• Primary gonococcal dermatitis
  Primary gonococcal dermatitis
  Primary gonococcal dermatitis is a rare infection of the skin that occurs after primary inoculation of the skin from an infected focus....
  
  
• Pseudomonal pyoderma
  Pseudomonal pyoderma
  Pseudomonal pyoderma is a cutaneous condition, a superficial infection of the skin with P. aeruginosa....
  
  
• Pseudomonas hot-foot syndrome
  Pseudomonas hot-foot syndrome
  Pseudomonas hot-foot syndrome is a cutaneous condition that occurs on the plantar surface of children after swimming in pool water that has high concentrations of P. aeruginosa....
  
  
• Pyogenic paronychia
  Pyogenic paronychia
  Pyogenic paronychia is an inflammation of the folds of skin surrounding the nail caused by bacteria.Generally acute paronychia is a pyogenic paronychia as it is usually caused by a bacterial infection....
  
  
• Pyomyositis
  Pyomyositis
  Pyomyositis, also known as tropical pyomyositis or myositis tropicans, is a bacterial infection of the skeletal muscles which results in a pus-filled abscess. Pyomyositis is most common in tropical areas but can also occur in temperate zones....
  
  
• Q fever
  Q fever
  Q fever is a disease caused by infection with Coxiella burnetii, a bacterium that affects humans and other animals. This organism is uncommon but may be found in cattle, sheep, goats and other domestic mammals, including cats and dogs...
  
  
• Queensland tick typhus
  Queensland tick typhus
  Queensland tick typhus is a condition caused by a bacterium Rickettsia australis.It is transmitted by Ixodes holocyclus and Ixodes tasmani.- See also :* Typhus...
  
  
• Rat-bite fever
  Rat-bite fever
  Rat-bite fever is an acute, febrile human illness caused by bacteria transmitted by rodents, rats in most cases, which is passed from rodent to human via the rodent's urine or mucous secretions. Alternative names for rat bite fever include streptobacillary fever, streptobacillosis, spirillary...
  
  
• Recurrent toxin-mediated perineal erythema
  Recurrent toxin-mediated perineal erythema
  Recurrent toxin-mediated perineal erythema is an unusual condition that presents 2-3 days after a throat infection as a fine diffuse macular erythema of the perineal region....
  
  
• Rhinoscleroma
  Rhinoscleroma
  Rhinoscleroma, or simply Scleroma, is a chronic granulomatous bacterial disease of the nose that can sometimes infect the upper respiratory tract. It most commonly affects the nasal cavity—the nose is involved in 95-100 per cent of cases—however, it can also affect the nasopharynx, larynx, trachea,...
  
  
• Rickettsia aeschlimannii infection
  Rickettsia aeschlimannii infection
  Rickettsia aeschlimannii infection is a condition characterized by a rash of maculopapules.- See also :* Tick-borne lymphadenopathy* American tick bite fever* List of cutaneous conditions...
  
  
• Rickettsialpox
  Rickettsialpox
  Rickettsialpox is an illness caused by bacteria of the Rickettsia genus . Physician Robert Huebner and self-trained entomologist Charles Pomerantz played major roles in identifying the etiology of the disease after an outbreak in 1946 in a New York City apartment complex, documented in medical...
  
  
• Rocky Mountain spotted fever
  Rocky Mountain spotted fever
  Rocky Mountain spotted fever is the most lethal and most frequently reported rickettsial illness in the United States. It has been diagnosed throughout the Americas. Some synonyms for Rocky Mountain spotted fever in other countries include “tick typhus,” “Tobia fever” , “São Paulo fever” or “febre...
  
  
• Saber shin
  Saber shin
  Saber shin is a malformation of the tibia. It presents as a sharp anterior bowing of the tibia.Saber shin is a sharp-edged anteriorly convex tibia.-Causes:It can result from syphilis and yaws....
  
   (Anterior tibial bowing)
• Saddle nose
  Saddle nose
  Saddle nose is a condition associated with congenital syphilis, relapsing Polychondritis, Wegener's granulomatosis, cocaine abuse, and Leprosy, among other conditions. It is characterized by a loss of height of the nose, because of the collapse of the bridge....
  
  
• Salmonellosis
  Salmonellosis
  Salmonellosis is an infection with Salmonella bacteria. Most people infected with Salmonella develop diarrhea, fever, vomiting, and abdominal cramps 12 to 72 hours after infection. In most cases, the illness lasts four to seven days, and most people recover without treatment...
  
  
• Scarlet fever
  Scarlet fever
  Scarlet fever is a disease caused by exotoxin released by Streptococcus pyogenes. Once a major cause of death, it is now effectively treated with antibiotics...
  
  
• Scrub typhus
  Scrub typhus
  Scrub typhus or Bush typhus is a form of typhus caused by Orientia tsutsugamushi first isolated and identified in 1930 in Japan., accessdate: 16 October 2011...
  
   (Tsutsugamushi fever)
• Shigellosis
  Shigellosis
  Shigellosis, also known as bacillary dysentery or Marlow Syndrome, in its most severe manifestation, is a foodborne illness caused by infection by bacteria of the genus Shigella. Shigellosis rarely occurs in animals other than humans and other primates like monkeys and chimpanzees...
  
  
• Staphylococcal scalded skin syndrome
  Staphylococcal scalded skin syndrome
  Staphylococcal scalded skin syndrome, SSSS, also known as Pemphigus neonatorum or Ritter's disease, or Localized bullous impetigo is a dermatological condition caused by Staphylococcus aureus.-Pathophysiology:...
  
   (Pemphigus neonatorum, Ritter's disease)
• Streptococcal intertrigo
  Streptococcal intertrigo
  Streptococcal intertrigo is a cutaneous condition seen in infants and young children, characterized by a fiery-red erythema and maceration in the neck, axillae or inguinal folds....
  
  
• Superficial pustular folliculitis
  Superficial pustular folliculitis
  Superficial pustular folliculitis is a superifical folliculitis with thin-walled pustules at the folliclular openings....
  
   (Impetigo of Bockhart, Superficial folliculitis)
• Sycosis vulgaris
  Sycosis vulgaris
  Sycosis vulgaris is a cutaneous condition characterized by a chronic infection of the bearded region....
  
   (Barber's itch, Sycosis barbae)
• Syphilid
  Syphilid
  A syphilid is any of the cutaneous and mucous membrane lesions characteristic of secondary and tertiary syphilis....
  
  
• Syphilis
  Syphilis
  Syphilis is a sexually transmitted infection caused by the spirochete bacterium Treponema pallidum subspecies pallidum. The primary route of transmission is through sexual contact; however, it may also be transmitted from mother to fetus during pregnancy or at birth, resulting in congenital syphilis...
  
   (Lues)
• Tick-borne lymphadenopathy
  Tick-borne lymphadenopathy
  Tick-borne lymphadenopathy is a condition characterized by lymphadenopathy and a rash.- See also :* Epidemic typhus* Brill–Zinsser disease* Rickettsia aeschlimannii infection* List of cutaneous conditions...
  
  
• Toxic shock syndrome
  Toxic shock syndrome
  Toxic shock syndrome is a potentially fatal illness caused by a bacterial toxin. Different bacterial toxins may cause toxic shock syndrome, depending on the situation. The causative bacteria include Staphylococcus aureus and Streptococcus pyogenes...
  
   (Streptococcal toxic shock syndrome, Streptococcal toxic shock-like syndrome, Toxic streptococcal syndrome)
• Trench fever
  Trench fever
  Trench fever is a moderately serious disease transmitted by body lice. It infected armies in Flanders, France, Poland, Galicia, Italy, Salonika, Macedonia, Mesopotamia, and Egypt in World War I Trench fever (also known as "Five day fever", "Quintan fever" (febris Quintana in Latin), "Urban trench...
  
   (Five day fever, Quintan fever, Urban trench fever)
• Tropical ulcer
  Tropical ulcer
  Tropical ulcer is a lesion occurring in cutaneous leishmaniasis. It is caused by a variety of microorganisms, including mycobacteria...
  
   (Aden ulcer, Jungle rot, Malabar ulcer, Tropical phagedena)
• Tularemia
  Tularemia
  Tularemia is a serious infectious disease caused by the bacterium Francisella tularensis. A Gram-negative, nonmotile coccobacillus, the bacterium has several subspecies with varying degrees of virulence. The most important of those is F...
  
   (Deer fly fever, Ohara's disease, Pahvant Valley plague, Rabbit fever)
• Verruga peruana
  Verruga peruana
  Verruga peruana is the chronic delayed stage of infection by Bartonella bacilliformis....
  
  
• Vibrio vulnificus infection
• Yaws
  Yaws
  Yaws is a tropical infection of the skin, bones and joints caused by the spirochete bacterium Treponema pallidum pertenue...
  
   (Bouba, Frambösie, Parangi, Pian)

Mycobacterium-related

Mycobacterium-related cutaneous conditions are caused by mycobacterium

Mycobacterium

Mycobacterium is a genus of Actinobacteria, given its own family, the Mycobacteriaceae. The genus includes pathogens known to cause serious diseases in mammals, including tuberculosis and leprosy...

 infections.

• Aquarium granuloma
  Aquarium granuloma
  Aquarium granuloma is a skin condition caused by Mycobacterium marinum, characterized by a skin lesion that presents roughly three weeks after exposure....
  
   (Fish tank granuloma, Swimming pool granuloma)
• Borderline lepromatous leprosy
  Borderline lepromatous leprosy
  Borderline lepromatous leprosy is a skin condition with numerous, symmetrical skin lesions....
  
  
• Borderline leprosy
  Borderline leprosy
  Borderline leprosy is a cutaneous skin condition with numerous skin lesions that are red irregularly shaped plaques....
  
  
• Borderline tuberculoid leprosy
  Borderline tuberculoid leprosy
  Borderline tuberculoid leprosy is a cutaneous condition similar to tuberculoid leprosy except the skin lesions are smaller and more numerous....
  
  
• Buruli ulcer
  Buruli ulcer
  The Buruli ulcer is an infectious disease caused by Mycobacterium ulcerans. The genus also includes the causative agents of tuberculosis and leprosy...
  
   (Bairnsdale ulcer, Searl ulcer, Searle's ulcer)
• Erythema induratum (Bazin disease)
• Histoid leprosy
• Lepromatous leprosy
  Lepromatous leprosy
  Lepromatous leprosy is a skin condition consisting of pale macules.It results from the failure of Th1 cell activation which is necessary to eradicate the parasite....
  
  
• Leprosy
  Leprosy
  Leprosy or Hansen's disease is a chronic disease caused by the bacteria Mycobacterium leprae and Mycobacterium lepromatosis. Named after physician Gerhard Armauer Hansen, leprosy is primarily a granulomatous disease of the peripheral nerves and mucosa of the upper respiratory tract; skin lesions...
  
   (Hansen's disease)
• Lichen scrofulosorum
  Lichen scrofulosorum
  Lichen scrofulosorum is a rare tuberculid that presents as a lichenoid eruption of minute papules in children and adolescents with tuberculosis. The lesions are usually asymptomatic, closely grouped, skin-colored to reddish-brown papules, often perifollicular and are mainly found on the abdomen,...
  
   (Tuberculosis cutis lichenoides)
• Lupus vulgaris
  Lupus vulgaris
  Lupus vulgaris are painful cutaneous tuberculosis skin lesions with nodular appearance, most often on the face around nose, eyelids, lips, cheeks and ears. The lesions may ultimately develop into disfiguring skin ulcers if left untreated...
  
   (Tuberculosis luposa)
• Miliary tuberculosis
  Miliary tuberculosis
  Miliary tuberculosis is a form of tuberculosis that is characterized by a wide dissemination into the human body and by the tiny size of the lesions...
  
   (Disseminated tuberculosis, Tuberculosis cutis acuta generalisata, Tuberculosis cutis disseminata)
• Mycobacterium avium-intracellulare complex infection
• Mycobacterium haemophilum infection
• Mycobacterium kansasii infection
• Papulonecrotic tuberculid
  Papulonecrotic tuberculid
  Papulonecrotic tuberculid is usually an asymptomatic, chronic skin disorder, presenting in successive crops, skin lesions symmetrically distributed on the extensor extremities....
  
  
• Primary inoculation tuberculosis
  Primary inoculation tuberculosis
  Primary inoculation tuberculosis is a skin condition that develops at the site of inoculation of tubercle bacilli into a tuberculosis-free individual....
  
   (Cutaneous primary complex, Primary tuberculous complex, Tuberculous chancre)
• Rapid growing mycobacterium infection
• Scrofuloderma
  Scrofuloderma
  Scrofuloderma is a skin condition caused by tuberculous involvement of the skin by direct extension, usually from underlying tuberculous lymphadenitis....
  
   (Tuberculosis cutis colliquativa)
• Tuberculosis cutis orificialis
  Tuberculosis cutis orificialis
  Tuberculosis cutis orificialis is a form of cutaneous tuberculosis that occurs at the mucocutaneous borders of the nose, mouth, anus, urinary meatus, and vagina, and on the mucous membrane of the mouth or tongue....
  
   (Acute tuberculous ulcer, Orificial tuberculosis)
• Tuberculosis verrucosa cutis (Lupus verrucosus, Prosector's wart, Warty tuberculosis)
• Tuberculous cellulitis
  Tuberculous cellulitis
  Tuberculous cellulitis is a skin condition resulting from infection with mycobacterium, and presenting as cellulitis.- See also :* Lupus vulgaris* Metastatic tuberculous abscess or ulceration* Miliary tuberculosis* Skin lesion- References :...
  
  
• Tuberculous gumma
  Tuberculous gumma
  Tuberculous gumma is a cutaneous condition characterized histologically by massive necrosis...
  
   (Metastatic tuberculous abscess, Metastatic tuberculous ulcer)
• Tuberculoid leprosy
  Tuberculoid leprosy
  Tuberculoid leprosy is a skin condition characterized by solitary skin lesions that are asymmetrically distributed....
  
  

Mycosis-related

Mycosis-related cutaneous conditions are caused by fungi or yeast

Yeast

Yeasts are eukaryotic micro-organisms classified in the kingdom Fungi, with 1,500 species currently described estimated to be only 1% of all fungal species. Most reproduce asexually by mitosis, and many do so by an asymmetric division process called budding...

s, and may present as either a superficial or deep infection

Infection

An infection is the colonization of a host organism by parasite species. Infecting parasites seek to use the host's resources to reproduce, often resulting in disease...

 of the skin, hair, and/or nails.

• African histoplasmosis
  African histoplasmosis
  - External links :* Authors at the University of Nigeria have published , which includes a thorough reference list....
  
  
• Alternariosis
  Alternariosis
  Alternariosis is an infection by alternaria, presenting cutaneously as focal, ulcerated papules and plaques.Treatment with itraconazole has been reported....
  
  
• Antibiotic candidiasis
  Antibiotic candidiasis
  Antibiotic candidiasis is a Candidal infection caused by antibiotic use.- Causes :Antibiotic candidiasis can result from overuse or over-presciption of broad-spectrum antibiotics . Consequently, it is now rare for such antibiotics to be prescribed for extended periods...
  
   (Iatrogenic candidiasis)
• Black piedra
  Black piedra
  Black piedra is a form of piedra caused by Piedraia hortae.Terbinafine has been used in the treatment....
  
  
• Candidal intertrigo
  Candidal intertrigo
  Candidal intertrigo is an infection of the skin by Candida albicans, more specifically located between intertriginous folds of adjacent skin....
  
  
• Candidal onychomycosis
  Candidal onychomycosis
  Candidal onychomycosis is an infection of the nail plate by fungus caused by Candida albicans....
  
  
• Candidal paronychia
  Candidal paronychia
  Candidal paronychia is an inflammation of the nail fold produced by Candida albicans....
  
  
• Candidal vulvovaginitis
  Candidal vulvovaginitis
  Candidal vulvovaginitis is an infection of the vagina’s mucous membranes by Candida albicans. Up to 75% of women will have thrush at some point in their lives, and approximately 5% will have recurring episodes.-Cause and pathophysiology:...
  
  
• Candidid
• Chromoblastomycosis
  Chromoblastomycosis
  Chromoblastomycosis is a long-term fungal infection of the skin and subcutaneous tissue . The infection occurs most commonly in tropical or subtropical climates, often in rural areas...
  
   (Chromomycosis, Cladosporiosis, Fonseca's disease, Pedroso's disease, Phaeosporotrichosis, Verrucous dermatitis)
• Chronic mucocutaneous candidiasis
  Chronic mucocutaneous candidiasis
  Chronic mucocutaneous candidiasis is an immune disorder of T cells. It is characterized by chronic infections with Candida that are limited to mucosal surfaces, skin, and nails. However, it can also be associated with other types of infections, such as human papilloma virus.An association with...
  
  
• Coccidioidomycosis
  Coccidioidomycosis
  Coccidioidomycosis is a fungal disease caused by Coccidioides immitis or C. posadasii. It is endemic in certain parts of Arizona, California, Nevada, New Mexico, Texas, Utah and northwestern Mexico.C...
  
   (California disease, Desert rheumatism, San Joaquin Valley fever, Valley fever)
• Congenital cutaneous candidiasis
  Congenital cutaneous candidiasis
  Congenital cutaneous candidiasis is a skin condition that results in newborn babies due to premature rupture of membranes together with a birth canal infected with Candida albicans....
  
  
• Cryptococcosis
  Cryptococcosis
  Cryptococcosis, or cryptococcal disease, is a potentially fatal fungal disease. It is caused by one of two species; Cryptococcus neoformans and Cryptococcus gattii. These were all previously thought to be subspecies of C...
  
  
• Dermatophytid
• Diaper candidiasis
  Diaper candidiasis
  Diaper candidiasis is an infection of a child's diaper area by Candida albicans....
  
  
• Disseminated coccidioidomycosis
  Disseminated coccidioidomycosis
  Disseminated coccidioidomycosis is a systemic infection with Coccidioides immitis, in which 15-20% of people develop skin lesions....
  
   (Coccidioidal granuloma)
• Distal subungual onychomycosis
  Distal subungual onychomycosis
  Distal subungual onychomycosis is an infection of the nail plate by fungus, primarily involving the distal nail plate....
  
  
• Entomophthoromycosis
• Erosio interdigitalis blastomycetica
  Erosio interdigitalis blastomycetica
  Erosio interdigitalis blastomycetica is a skin condition caused by a Candida albicans infection, characterized by an oval-shaped area of macerated white skin on the web between and extending onto the sides of the fingers....
  
   
  
• Favus
  Favus
  Favus is a disease usually affecting the scalp, but occurring occasionally on any part of the skin, and even at times on mucous membranes.-Presentation:...
  
  
• Fungal folliculitis
  Fungal folliculitis
  Fungal folliculitis is a skin condition characterized by a deep, pustular type of tinea circinata resembling a carbuncle or kerion....
  
   (Majocchi granuloma)
• Fusariosis
  Fusariosis
  Fusariosis is an infection seen in neutropenic patients, and is a significant opportunistic pathogen in patients with hematologic malignancy.It is associated with infections with Fusarium species, such as Fusarium proliferatum....
  
  
• Geotrichosis
  Geotrichosis
  Geotrichosis is a mycosis caused by Geotrichum candidum.The lungs are the primary organ affected, but other systems can be involved....
  
  
• Granuloma gluteale infantum
  Granuloma gluteale infantum
  Granuloma gluteale infantum is a cutaneous condition that appears in the anogenital region of infants as a complication of diaper dermatitis.According to some, no granulomas are actually found....
  
  
• Histoplasmosis
  Histoplasmosis
  Histoplasmosis is a disease caused by the fungus Histoplasma capsulatum. Symptoms of this infection vary greatly, but the disease primarily affects the lungs...
  
   (Cave disease, Darling's disease, Ohio Valley disease, Reticuloendotheliosis)
• Hyalohyphomycosis
  Hyalohyphomycosis
  Hyalohyphomycosis is a group of opportunistic mycotic infections caused by nondematiaceous molds, and may be contrasted with phaeohyphomycosis.A hyalohyphomycetes example is Fusarium....
  
  
• Kerion
  Kerion
  Kerion is the result of the host's response to a fungal ringworm infection of the hair follicles of the scalp and beard accompanied by secondary bacterial infection. It usually presents itself as raised, spongy lesions. This honeycomb is severely painful inflammatory reaction with deep suppurative...
  
  
• Lobomycosis (Keloidal blastomycosis, Lacaziosis, Lobo's disease)
• Mucormycosis
  Mucormycosis
  Zygomycosis is the broadest term to refer to infections caused by bread mold fungi of the zygomycota phylum. However, because zygomycota has been identified as polyphyletic, and is not included in modern fungal classification systems, the diseases that Zygomycosis can refer to are better called by...
  
  
• Mycetoma
  Eumycetoma
  Eumycetoma is a chronic, specific, granulomatous, fungal disease. It mainly affects the foot; and Mycetoma pedis is also known as Madura foot. This infection is endemic in Africa, India, and Central and South America.-Causes and presentation:...
  
   (Madura foot, Maduromycosis)
• North American blastomycosis (Blastomycetic dermatitis, Blastomycosis, Gilchrist's disease)
• Onychomycosis
  Onychomycosis
  Onychomycosis means fungal infection of the nail. It is the most common disease of the nails and constitutes about a half of all nail abnormalities....
  
   (Dermatophytic onychomycosis, Ringworm of the nail, Tinea unguium)
• Oral candidiasis
  Oral candidiasis
  Oral candidiasis is an infection of yeast fungi of the genus Candida on the mucous membranes of the mouth. It is frequently caused by Candida albicans, or less commonly by Candida glabrata or Candida tropicalis...
  
   (Thrush)
• Otomycosis
  Otomycosis
  Otomycosis is a fungal ear infection, a superficial mycotic infection of the outer ear canal. It is more common in the tropical countries. The infection may be either subacute or acute and is characterized by inflammation, pruritus, scaling, and severe discomfort...
  
  
• Perianal candidiasis
  Perianal candidiasis
  Perianal candidiasis is a skin condition caused by infection by Candida albicans, and may present as pruritus ani....
  
  
• Perlèche (Angular cheilitis)
• Phaeohyphomycosis
  Phaeohyphomycosis
  Phaeohyphomycosis is a heterogeneous group of mycotic infections caused by dematiaceous fungi whose morphologic characteristics in tissue include hyphae, yeast-like cells, or a combination of these.It can be associated with Alternaria....
  
  
• Piedra
  Piedra
  Piedra is a hair disease caused by a fungus.Types include:* White piedra* Black piedra...
  
   (Trichosporosis)
• Pityrosporum folliculitis
  Pityrosporum folliculitis
  Pityrosporum folliculitis or Malassezia folliculitis is a skin condition caused by infection by pityrosporum yeast.The skin of the upper trunk area like the back, upper arms and sometimes the neck is often affected and this condition is often seen in young to middle aged adults...
  
  
• Primary cutaneous aspergillosis
  Primary cutaneous aspergillosis
  Primary cutaneous aspergillosis is a rare skin condition most often occurring at the site of intravenous cannulas in immunosuppressed patients....
  
  
• Primary cutaneous coccidioidomycosis
  Primary cutaneous coccidioidomycosis
  Primary cutaneous coccidioidomycosis is a skin condition cause by Coccidioides immitis following a definite history of inoculation or a colonized splinter is found in the skin lesion....
  
  
• Primary cutaneous histoplasmosis
  Primary cutaneous histoplasmosis
  Primary cutaneous histoplasmosis is a rare skin condition, reported on the penis, characterized by a chancre-type lesion with regional adenopathy....
  
  
• Primary pulmonary coccidioidomycosis
  Primary pulmonary coccidioidomycosis
  Primary pulmonary coccidioidomycosis is an infection caused by inhalation of Coccidioides immitis. Once pulmonary symptoms subside, about 30% of women and 15% of men will have allergic skin manifestations in the form of erythema nodosum...
  
  
• Primary pulmonary histoplasmosis
  Primary pulmonary histoplasmosis
  Primary pulmonary histoplasmosis is caused by inhalation of Histoplasma capsulatum spores, and approximately 10% of people with this acute infection develop erythema nodosum....
  
  
• Progressive disseminated histoplasmosis
  Progressive disseminated histoplasmosis
  Progressive disseminated histoplasmosis is an infection caused by Histoplasma capsulatum, and most people who develop this severe form of histoplasmosis are immunocompromised or taking systemic corticosteroids. Skin lesions are present in approximately 6% of patients with dissemination....
  
  
• Proximal subungual onychomycosis
  Proximal subungual onychomycosis
  Proximal subungual onychomycosis is an infection of the nail plate by fungus, primarily affecting the proximal nailfold....
  
  
• Rhinosporidiosis
  Rhinosporidiosis
  -Classification:This organism was previously considered to be a fungus, and rhinosporidiosis is classified as a fungal disease under ICD-10.It is now considered to be a parasite, classified under Mesomycetozoea....
  
  
• South American blastomycosis (Brazilian blastomycosis, Paracoccidioidal granuloma, paracoccidioidomycosis)
• Sporotrichosis
  Sporotrichosis
  Sporotrichosis is a disease caused by the infection of the fungus Sporothrix schenckii. This fungal disease usually affects the skin, although other rare forms can affect the lungs, joints, bones, and even the brain...
  
   (Rose gardener's disease)
• Systemic candidiasis
  Systemic candidiasis
  Systemic candidiasis is an infection of Candida albicans causing disseminated disease and sepsis, invariably when host defenses are compromised....
  
  
• Tinea barbae
  Tinea barbae
  Tinea barbæ is a fungal infection of the hair. Tinea barbae is due to a dermatophytic infection around the bearded area of men. Generally, the infection occurs as a follicular inflammation, or as a cutaneous granulomatous lesion, i.e. a chronic inflammatory reaction. It is one of the causes of...
  
   (Barber's itch, Ringworm of the beard, Tinea sycosis)
  
• Tinea capitis
  Tinea capitis
  Tinea capitis is a superficial fungal infection of the scalp. The disease is primarily caused by dermatophytes in the Trichophyton and Microsporum genera that invade the hair shaft...
  
   (Herpes tonsurans, Ringworm of the hair, Ringworm of the scalp, Scalp ringworm, Tinea tonsurans)
• Tinea corporis
  Tinea corporis
  Tinea corporis is a superficial fungal infection of the arms and legs, especially on glabrous skin, however it may occur on any part of the body.-Symptoms:...
  
   (Ringworm, Tinea circinata, Tinea glabrosa)
• Tinea corporis gladiatorum
  Tinea corporis gladiatorum
  Tinea corporis gladiatorum is a dermatophytic infection present in wrestlers, with skin lesions typically found on the head, neck, and arms....
  
  
• Tinea cruris (Crotch itch, Eczema marginatum, Gym itch, Jock itch, Ringworm of the groin)
• Tinea faciei
  Tinea faciei
  Tinea faciei is a fungal infection of the face.It generally appears as a red rash on the face, followed by patches of small, raised bumps. The skin may peel while it is being treated....
  
  
• Tinea imbricata
  Tinea imbricata
  Tinea imbricata is a superficial fungal infection of the skin limited to southwest Polynesia, Melanesia, Southeast Asia, India, and Central America.It is associated with Trichophyton concentricum....
  
   (Tokelau)
• Tinea incognito
  Tinea incognito
  Tinea incognito is a fungal infection of the skin caused by the presence of a topical immunosuppressive agent. The usual agent is a topical corticosteroid . As the skin fungal infection has lost some of the characteristic features due to suppression of inflammation, it may have a poorly defined...
  
  
• Tinea manuum
  Tinea manuum
  Tinea Manuum is a fungal infection of the hand. It is typically more aggressive than tinea pedis but similar in look. Itching, burning, cracking, and scaling are observable and may be transmitted sexually or otherwise, whether or not symptoms are present....
  
  
• Tinea nigra
  Tinea nigra
  Tinea Nigra is a superficial fungal infection that causes dark brown to black painless patches on the palms of the hands and the soles of the feet.- Causes :...
  
   (Superficial phaeohyphomycosis, Tinea nigra palmaris et plantaris)
• Tinea pedis (Athlete's foot, Ringworm of the foot)
• Tinea versicolor
  Tinea versicolor
  Tinea versicolor is a condition characterized by a rash on the trunk and proximal extremities. Recent research has shown that the majority of Tinea versicolor is caused by the Malassezia globosa fungus, although Malassezia furfur is responsible for a small number of cases...
  
   (Dermatomycosis furfuracea, Pityriasis versicolor, Tinea flava)
• White piedra
  White piedra
  White piedra is a mycosis of the hair caused by several species of fungi in the genus Trichosporon. It is characterized by soft nodules composed of yeast cells and arthroconidia that encompass hair shafts.-Treatment:...
  
  
• White superficial onychomycosis
  White superficial onychomycosis
  White superficial onychomycosis is an infection of the nail plate by fungus, primarily affecting the surface of the nail....
  
  
• Zygomycosis (Phycomycosis)

Parasitic infestations, stings, and bites

Parasitic infestations, stings, and bites in humans are caused by several groups of organisms belonging to the following phyla

Phylum

In biology, a phylum The term was coined by Georges Cuvier from Greek φῦλον phylon, "race, stock," related to φυλή phyle, "tribe, clan." is a taxonomic rank below kingdom and above class. "Phylum" is equivalent to the botanical term division....

: Annelida, Arthropoda, Bryozoa

Bryozoa

The Bryozoa, also known as Ectoprocta or commonly as moss animals, are a phylum of aquatic invertebrate animals. Typically about long, they are filter feeders that sieve food particles out of the water using a retractable lophophore, a "crown" of tentacles lined with cilia...

, Chordata, Cnidaria

Cnidaria

Cnidaria is a phylum containing over 9,000 species of animals found exclusively in aquatic and mostly marine environments. Their distinguishing feature is cnidocytes, specialized cells that they use mainly for capturing prey. Their bodies consist of mesoglea, a non-living jelly-like substance,...

, Cyanobacteria, Echinodermata, Nemathelminthes, Platyhelminthes, and Protozoa

Protozoa

Protozoa are a diverse group of single-cells eukaryotic organisms, many of which are motile. Throughout history, protozoa have been defined as single-cell protists with animal-like behavior, e.g., movement...

.

• Acanthamoeba infection
  Acanthamoeba infection
  Acanthamoeba infection is a cutaneous condition resulting from Acanthamoeba that may result in various skin lesions....
  
  
• Amebiasis cutis
  Amebiasis cutis
  Amebiasis cutis is a cutaneous condition characterized by ulcers caused by Entamoeba histolytica....
  
  
• Ant sting
  Ant sting
  Ant stings are a cutaneous condition caused by stinging venomous ants, always painful, but most painful when involving fire ants.- Treatment :First aid for fire ant bites includes external treatments and oral medicines....
  
  
• Arachnidism
  Arachnidism
  Arachnidism is a medical condition, simply defined as envenomation by a spider bite, which, depending on the species, will have various effects. Bites from the widow spiders produce a condition known as Latrodectism, while bites from the recluse spiders cause Loxoscelism...
  
  
• Balamuthia infection
  Balamuthia infection
  Balamuthia infection is a cutaneous condition resulting from Balamuthia that may result in various skin lesions....
  
  
• Bedbug infestation (Bedbug bite, Cimicosis)
• Bee and wasp stings
• Blister beetle dermatitis
  Blister beetle dermatitis
  Blister beetle dermatitis is a cutaneous condition that occurs after contact with any of several types of beetles, including those from the Meloidae and Oedemeridae families...
  
  
• Bombardier beetle burn
• Bristleworm sting
  Bristleworm sting
  Bristleworm stings are a cutaneous condition caused by contact with bristleworms, in which an allergic or irritant reaction may result....
  
   
• Centipede bite
  Centipede bite
  A centipede bite is an injury resulting from the action of a centipede's forcipules, pincer-like appendages that pierce the skin and inject venom into the wound. Such a wound is not technically a bite, as the forcipules are modified legs rather than true mouthparts...
  
  
• Cheyletiella dermatitis
• Chigger bite
  Chigger bite
  Chigger bites are a cutaneous condition caused by trombiculid mites....
  
  
• Coolie itch
  Coolie itch
  Coolie itch is a cutaneous condition caused by Rhizoglyphus parasiticus, characterized by an intense pruritus.Rhizoglyphus parasiticus is a type of mite....
  
  
• Copra itch
  Copra itch
  Copra itch is a cutaneous condition that occurs on persons handling copra who are subject to Tyrophagus longior mite bites....
  
  
• Coral dermatitis
  Coral dermatitis
  Coral dermatitis are a cutaneous condition caused by injury from the exoskeleton of certain corals.- References :...
  
  
• Creeping eruption (Cutaneous larva migrans)
• Cutaneous leishmaniasis
  Cutaneous leishmaniasis
  Cutaneous leishmaniasis is the most common form of leishmaniasis. It is a skin infection caused by a single-celled parasite that is transmitted by sandfly bites...
  
   (Aleppo boil, Baghdad boil, Bay sore, Biskra button, Chiclero ulcer, Delhi boil, Kandahar sore, Lahore sore, Leishmaniasis tropica, Oriental sore, Pian bois, Uta)
• Cysticercosis cutis
• Demodex mite bite
  Demodex mite bite
  Demodex mite bite is a cutaneous condition caused by infestation by Demodex folliculorum....
  
  
• Dogger Bank itch
  Dogger Bank itch
  Dogger Bank itch is a cutaneous condition characterized by an eczematous dermatitis caused by exposure to the sea chervil, Alcyonidium diaphanum, a seaweed-like animal colony...
  
  
• Dracunculiasis
  Dracunculiasis
  Dracunculiasis , also called guinea worm disease , is a parasitic infection caused by Dracunculus medinensis, a long and very thin nematode . The infection begins when a person drinks stagnant water contaminated with copepods infested by the larvae of the guinea worm...
  
   (Dracontiasis, Guinea worm disease, Medina worm)
• Echinococcosis
  Echinococcosis
  Echinococcosis, which is often referred to as hydatid disease or echinococcal disease, is a parasitic disease that affects both humans and other mammals, such as sheep, dogs, rodents and horses. There are three different forms of echinococcosis found in humans, each of which is caused by the larval...
  
   (Hydatid disease)
• Elephantiasis tropica
  Elephantiasis tropica
  Elephantiasis tropica is a cutaneous condition caused by infestation with filarial worms....
  
   (Elephantiasis arabum)
• Elephant skin
  Elephant skin
  Elephant skin is a term used to describe the thickening of human skin that may be associated with onchocerciasis....
  
  
• Enterobiasis
  Enterobiasis
  A pinworm infection or enterobiasis is a human parasitic disease and one of the most common childhood parasitic worm infections in the developed world. It is caused by infestation with the parasitic roundworm Enterobius vermicularis, commonly called the human pinworm...
  
   (Oxyuriasis, Pinworm infection, Seatworm infection)
• Erisipela de la costa
  Erisipela de la costa
  Erisipela de la costa is an acute phase of onchocerciasis characterized by swelling of the face with erythema and itching.. Onchocerciasis causes different kinds of skin changes and these changes vary in different geographic regions. This skin change, erisípela de la costa, of acute onchocerciasis...
  
  
• Funnel web spider bite
• Gamasoidosis
  Gamasoidosis
  Gamasoidosis is a cutaneous condition that occurs after contact with canaries, pigeons, and poultry, caused by two genera of mites, including Ornithonyssus and Dermanyssus....
  
  
• Gnathostomiasis
  Gnathostomiasis
  Gnathostomiasis is the human infection by the nematode Gnathostoma spinigerum and/or Gnathostoma hispidum, which infects vertebrates.-Synonyms:...
  
   (Larva migrans profundus)
• Grain itch
  Grain itch
  Grain itch is a cutaneous condition caused by several types of mites, and characterized by intense pruritus....
  
   (Barley itch, Mattress itch, Prairie itch, Straw itch)
• Grocer's itch
  Grocer's itch
  Grocer's itch is a cutaneous condition characterized by a pruritic dermatitis that occurs from coming into contact with mites such as Carpoglyphus passularum or Glyciphagus domesticus . Contact usually occurs when handling food with mites in it, such as figs, dates, prunes, grain, cheese or other...
  
  
• Head lice infestation (Cooties, Pediculosis capitis)
• Hookworm disease
  Hookworm disease
  Hookworm disease is a cutaneous condition characterized by skin lesions that are erythematous macules and papules. Specific types include:* Ancylostomiasis* Necatoriasis...
  
   (Ancylostomiasis, Ground itch, Necatoriasis, Uncinariasis)
• Human trypanosomiasis
  Human trypanosomiasis
  Human trypanosomiasis is a cutaneous condition caused by several species of trypanosomes, with skin manifestations usually being observed in the earlier stages of the disease as evanescent erythema, erythema multiforme, and edema, especially angioedema....
  
  
• Hydroid dermatitis
  Hydroid dermatitis
  Hydroid dermatitis is a cutaneous condition that occurs after contact with the small marine hydroid Halecium....
  
  
• Irukandji syndrome
  Irukandji syndrome
  Irukandji syndrome is a condition that is induced by venomization through the sting of Carukia barnesi, a species of Irukandji jellyfish, and other cubozoans. The condition is rarely fatal, but if immediate medical action is not taken, within only 20 minutes the victim could go into cardiac arrest...
  
  
• Jellyfish dermatitis
  Jellyfish dermatitis
  Jellyfish dermatitis is a cutaneous condition caused by stings from a jellyfish.- See also :* List of cutaneous conditions* Portuguese man-of-war dermatitis* Skin lesion...
  
  
• Ked itch
  Ked itch
  Ked itch is a cutaneous condition caused by sheep ked which feed by thrusting its sharp mouth parts into the skin and sucking blood....
  
  
• Larva currens
  Larva currens
  Larva currens is an itchy, cutaneous condition caused by infections with Strongyloides stercoralis that intermittently comes and goes every few hours....
  
  
• Latrodectism
  Latrodectism
  Latrodectism is the clinical syndrome caused by the neurotoxic venom , that can be injected by the bite of any spider that is a member of the spider genus Latrodectus, in the family Theridiidae....
  
   (Widow spider bite)
• Leech bite
  Leech bite
  Leech bites are caused by leeches the class Hirudinea, which may be of marine, freshwater, or terrestrial types.Hand removing a leech is advised since they don't burrow into the skin nor the head in the wound, while other texts advice shaking salt onto the body of the leech or scorch the leech with...
  
  
• Leopard skin
  Leopard skin
  Leopard skin refers to the spotted depigmentation of the skin that may occur with onchocerciasis....
  
  
• Lepidopterism
  Lepidopterism
  -External links:* on eMedicine...
  
   (Caripito itch, Caterpillar dermatitis, Moth dermatitis)
• Lizard bite
  Lizard bite
  Lizard bite is a cutaneous condition caused by bites from various lizards, including Heloderma suspectum.- References :...
  
  
• Lizard skin
  Lizard skin
  Lizard skin is a term used to describe the thickened, wrinkled skin changes that may result with onchocerciasis....
  
  
• Loaiasis (Calabar swelling, Fugitive swelling, Loa loa, Tropical swelling)
• Loxoscelism
  Loxoscelism
  thumb|Scars left over from a healed recluse biteLoxoscelism is a condition produced by the bite of the recluse spiders . It is the only proven cause of arachnogenic necrosis in humans. While there is no known therapy effective for loxoscelism, there has been research on potential antivenoms and...
  
   (Brown recluse spider bite, Necrotic cutaneous loxoscelism)
• Mal morando
  Mal morando
  Mal morando is a cutaneous condition caused by onchocerciasis characterized by inflammation that is accompanied by hyperpigmentation....
  
  
• Millipede burn
  Millipede burn
  Millipede burns are a cutaneous condition caused by some millipedes that secrete a toxic liquid that causes a brownish pigmentation or burn when it comes into contact with the skin. Some millipedes produce quinones in their defensive secretions, which have been reported to cause brown staining of...
  
  
• Mosquito bite
• Mucocutaneous leishmaniasis
  Mucocutaneous leishmaniasis
  Mucocutaneous leishmaniasis is a cutaneous condition which occurs at the site of a fly bite, and is characterized by an ulceration of the skin....
  
   (Espundia, Leishmaniasis americana)
• Myiasis
  Myiasis
  Myiasis is a general term for infection by parasitic fly larvae feeding on the host's necrotic or living tissue. Colloquialisms for myiasis include flystrike, blowfly strike, and fly-blown. In Greek, "myia" means fly....
  
  
• Nairobi fly dermatitis
  Nairobi fly dermatitis
  Nairobi fly dermatitis is a cutaneous condition caused by Paederus eximius, a rove beetle found in Northern Kenya....
  
   (Kenya fly dermatitis, Nairobi eye)
• Nematode dermatitis
  Nematode dermatitis
  Nematode dermatitis is a cutaneous condition characterized by widespread folliculitis caused by Ancylostoma caninum....
  
  
• Norwegian scabies (Crusted scabies)
  
• Onchocerciasis
  Onchocerciasis
  Onchocerciasis , also known as river blindness and Robles' disease, is a parasitic disease caused by infection by Onchocerca volvulus, a nematode . Onchocerciasis is the world's second-leading infectious cause of blindness. It is not the nematode, but its endosymbiont, Wolbachia pipientis, that...
  
  
• Ophthalmia nodosa
  Ophthalmia nodosa
  Ophthalmia nodosa is a cutaneous condition characterized by inflammation of the eye due to lodging of caterpillar hairs in the conjunctiva, cornea, or iris....
  
  
• Paederus dermatitis
  Paederus dermatitis
  Paederus dermatitis is skin irritation resulting from contact with the hemolymph of certain rove beetles, a group that includes the genus Paederus...
  
  
• Pediculosis corporis
  Pediculosis corporis
  Pediculosis corporis is a cutaneous condition caused by body lice that lay their eggs in the seams of clothing.- See also :* Pediculosis* Skin lesion...
  
   (Pediculosis vestimenti, Vagabond's disease)
• Pediculosis pubis
  Pediculosis pubis
  Pediculosis pubis is a disease caused by the crab louse Phthirus pubis, a parasitic insect notorious for infesting human pubic hair. The species may also live on other areas with hair, including the eyelashes causing pediculosis ciliaris. Infestation usually lead to intense itching in the pubic area...
  
   (Crabs, Phthirus pubis, Pthirus pubis, Pubic lice)
• Pneumocystosis
  Pneumocystosis
  Pneumocystosis is an infection by Pneumocystis jirovecii that primarily occurs as a pulmonary infection AIDS patients, with extrapulmonary involvement being uncommon but, if occurring in the skin, presenting most often as nodular growths in the auditory canal....
  
   (often classified as fungal)
• Portuguese man-of-war dermatitis
  Portuguese man-of-war dermatitis
  Portuguese man-of-war dermatitis is a cutaneous condition caused by stings from a Portuguese man-of-war....
  
  
• Post-kala-azar dermal leishmaniasis
  Post-kala-azar dermal leishmaniasis
  Post-kala-azar dermal leishmaniasis is a cutaneous condition that is characterized by a macular, depigmented eruption found mainly on the face, arms, and upper part of the trunk. It occurs years after the successful treatment of visceral leishmaniasis...
  
   (Post-kala-azar dermatosis)
• Protothecosis
  Protothecosis
  Protothecosis is a disease found in dogs, cats, cattle, and humans caused by a type of green alga known as Prototheca that lacks chlorophyll. It and its close relative Helicosporidium are unusual in that they are actually green algae that have become parasites. The two most common species are...
  
  
• Pulicosis
  Pulicosis
  Pulicosis is a skin condition caused by several species of fleas, including the cat flea Ctenocephalides felis. The condition manifests itself after as few as one flea bite and may not even be noticed. Within minutes skin irritation begins. This can range from extremely mild to severe...
  
   (Flea bites)
• Reduviid bite
• Scabies
  Scabies
  Scabies , known colloquially as the seven-year itch, is a contagious skin infection that occurs among humans and other animals. It is caused by a tiny and usually not directly visible parasite, the mite Sarcoptes scabiei, which burrows under the host's skin, causing intense allergic itching...
  
   (Itch mite infestation, Seven-year itch)
• Scorpion sting
  Scorpion sting
  Scorpion stings are a cutaneous condition caused by the stinging of scorpions, usually resulting in pain, paresthesia, and variable swelling. The anatomical part of the scorpion that delivers the sting is called a "telson".- See also :* Scorpion venom...
  
  
• Sea anemone dermatitis
  Sea anemone dermatitis
  Sea anemone dermatitis is a cutaneous condition similar to jellyfish and hydroid dermatitis, caused by contact with certain sea anemones....
  
  
• Seabather's eruption
  Seabather's eruption
  Seabather's eruption is a pruritic dermatitis caused by a hypersensitivity reaction to the immature nematocysts of larval-stage thimble jellyfish , sea anemones and other larval cnidarians....
  
   (Sea lice)
• Sea urchin injury
  Sea urchin injury
  Sea urchin injuries are caused by contact with sea urchins, and are characterized by puncture wounds inflicted by the animal's brittle, fragile spines. -Process:...
  
  
• Seaweed dermatitis
  Seaweed dermatitis
  Seaweed dermatitis is a cutaneous condition characterized by inflammation of the skin caused by marine alga, specifically Lyngbya majuscula....
  
  
• Snake bite
• Sowda
• Sparganosis
  Sparganosis
  Sparganosis is a parasitic infection caused by the plerocercoid larvae of diphyllobothroid tapeworms belonging to the genus Spirometra. First described by Manson in 1882, the infection is transmitted by ingestion of contaminated water, ingestion of a second intermediate host such as a frog or...
  
  
• Spider bite
  Spider bite
  A spider bite is an injury resulting from the bites of spiders or other closely related arachnids.Spiders are active hunters and rely heavily on their bites to paralyze and kill their prey before consuming it. They also bite in self defense...
  
  
• Stingray injury
  Stingray injury
  Stingray injuries are caused by the venomous tail spines or stingers of rays in the order Myliobatiformes, most significantly those belonging to the families Dasyatidae, Urotrygonidae, Urolophidae, and Potamotrygonidae. Stingrays generally do not attack aggressively or even actively defend...
  
  
• Swimmer's itch
  Swimmer's itch
  Swimmer’s itch, also known as lake itch, duck itch, cercarial dermatitis, and Schistosome cercarial dermatitis, is a short-term, immune reaction occurring in the skin of humans that have been infected by water-borne schistosomatidae...
  
   (Cercarial dermatitis, Schistosome cercarial dermatitis)
  
• Tarantula bite
• Tick bite
• Toxoplasmosis
  Toxoplasmosis
  Toxoplasmosis is a parasitic disease caused by the protozoan Toxoplasma gondii. The parasite infects most genera of warm-blooded animals, including humans, but the primary host is the felid family. Animals are infected by eating infected meat, by ingestion of feces of a cat that has itself...
  
  
• Trichinosis
  Trichinosis
  Trichinosis, also called trichinellosis, or trichiniasis, is a parasitic disease caused by eating raw or undercooked pork or wild game infected with the larvae of a species of roundworm Trichinella spiralis, commonly called the trichina worm. There are eight Trichinella species; five are...
  
  
• Trichomoniasis
  Trichomoniasis
  Trichomoniasis, sometimes referred to as "trich", is a common cause of vaginitis. It is a sexually transmitted disease, and is caused by the single-celled protozoan parasite Trichomonas vaginalis producing mechanical stress on host cells and then ingesting cell fragments after cell death...
  
  
• Tungiasis
  Tungiasis
  Tungiasis is an inflammatory skin disease caused by infection of the female ectoparasitic Tunga penetrans flea , found in the tropical parts of Africa, the Caribbean, Central and South America, and India...
  
   (Bicho de pie, Chigoe flea bite, Jigger bite, Nigua, Pique)
• Visceral leishmaniasis
  Visceral leishmaniasis
  Visceral leishmaniasis , also known as kala-azar, black fever, and Dumdum fever, is the most severe form of leishmaniasis. Leishmaniasis is a disease caused by protozoan parasites of the Leishmania genus. This disease is the second-largest parasitic killer in the world , responsible for an...
  
   (Dumdum fever, Kala-azar)
• Visceral schistosomiasis (Bilharziasis)
• Viscerotropic leishmaniasis
  Viscerotropic leishmaniasis
  Viscerotropic leishmaniasis is a systemic infection reported in soldiers fighting in Operation Desert Storm in Saudi Arabia....
  
  
• Wheat warehouse itch
  Wheat warehouse itch
  Wheat warehouse itch is a cutaneous condition caused by a mite, Cheyletus malaccensis....
  
  

Virus-related

Virus-related cutaneous conditions are caused by two main groups of virus

Virus

A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

es–DNA

DNA virus

A DNA virus is a virus that has DNA as its genetic material and replicates using a DNA-dependent DNA polymerase. The nucleic acid is usually double-stranded DNA but may also be single-stranded DNA . DNA viruses belong to either Group I or Group II of the Baltimore classification system for viruses...

 and RNA

RNA virus

An RNA virus is a virus that has RNA as its genetic material. This nucleic acid is usually single-stranded RNA but may be double-stranded RNA...

 types–both of which are obligatory

Obligation

An obligation is a requirement to take some course of action, whether legal or moral. There are also obligations in other normative contexts, such as obligations of etiquette, social obligations, and possibly...

 intracellular

Intracellular

Not to be confused with intercellular, meaning "between cells".In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".It is used in contrast to extracellular...

 parasites.

• Alphavirus infection
  Alphavirus infection
  Alphavirus infection may be caused by a Sindbis virus infection, and result in a cutaneous eruption of multiple, erythematous, 4- to 4-mm papules....
  
  
• Asymmetric periflexural exanthem of childhood
  Asymmetric periflexural exanthem of childhood
  Asymmetric periflexural exanthem of childhood is a cutaneous condition that occurs primarily in the late winter and early spring, most common in Europe, and affecting girls more often than boys....
  
   (Unilateral laterothoracic exanthem)
• B virus infection
  B virus infection
  B virus infection is endemic in Asiatic Old World monkeys and may infect other monkeys housed in close quarters with infected monkeys....
  
  
• Boston exanthem disease
  Boston exanthem disease
  Boston exanthem disease is a cutaneous condition that occurred as an epidemic in Boston and was caused by echovirus 16....
  
  
• Bovine papular stomatitis
  Bovine papular stomatitis
  Bovine papular stomatitis is a disease caused by a virus of the family Poxviridae and the genus Parapoxvirus. It occurs worldwide in cattle. Symptoms include reddish, raised, sometimes ulcerative lesions on the lips, muzzle, and in the mouth. It usually occurs before the age of two years. ...
  
  
• Bowenoid papulosis
  Bowenoid papulosis
  Bowenoid papulosis is a cutaneous condition characterized by the presence of pigmented verrucous papules on the body of the penis. They are associated with human papillomavirus, the causative agent of genital warts...
  
  
• Buffalopox
  Buffalopox
  Buffalopox is caused by buffalopox virus ; it is a Poxviridae for which the natural host is buffalo. It mainly infects buffalo but has been known to infect cows and humans. It is classified in the Orthopoxvirus genus and the subfamily Chordopoxvirinae...
  
  
• Butcher's wart
  Butcher's wart
  Butcher's wart is a cutaneous condition caused by a small group of viruses that infect the skin.An association with human papillomavirus 7 has been suggested....
  
  
• Chikungunya fever
• Condylomata acuminata
• Congenital rubella syndrome
  Congenital rubella syndrome
  Congenital rubella syndrome can occur in a developing fetus of a pregnant woman who has contracted rubella during her first trimester. If infection occurs 0–28 days before conception, there is a 43% chance the infant will be affected. If the infection occurs 0–12 weeks after conception, there is a...
  
  
• Cowpox
  Cowpox
  Cowpox is a skin disease caused by a virus known as the Cowpox virus. The pox is related to the vaccinia virus and got its name from the distribution of the disease when dairymaids touched the udders of infected cows. The ailment manifests itself in the form of red blisters and is transmitted by...
  
  
• Cytomegalic inclusion disease
• Dengue (Break-bone fever)
• Disseminated herpes zoster
  Disseminated herpes zoster
  Disseminated herpes zoster is an infection caused by the Herpes varicella zoster virus. This is the same virus that causes herpes zoster and chickenpox...
  
  
• Eczema herpeticum
  Eczema herpeticum
  Eczema herpeticum is a rare but severe disseminated herpes infection that generally occurs at sites of skin damage produced by, for example, atopic dermatitis, burns, or eczema...
  
   (Kaposi's varicelliform eruption)
  
• Eczema vaccinatum
  Eczema vaccinatum
  Eczema vaccinatum is a rare severe adverse reaction to smallpox vaccination.It is characterized by serious local or disseminated, umbilicated, vesicular, crusting skin rashes in the face, neck, chest, abdomen, upper limbs and hands, caused by widespread infection of the skin in people with previous...
  
  
• Epidermodysplasia verruciformis
  Epidermodysplasia verruciformis
  Epidermodysplasia verruciformis is an extremely rare autosomal recessive genetic hereditary skin disorder associated with a high risk of carcinoma of the skin. It is characterized by abnormal susceptibility to human papillomaviruses of the skin...
  
  
• Eruptive pseudoangiomatosis
  Eruptive pseudoangiomatosis
  Eruptive pseudoangiomatosis is a cutaneous condition characterized by the sudden appearance of 2- to 4-mm blanchable red papules.It can appear in children or adults.The papules appear similar to hemangiomas ....
  
  
• Erythema infectiosum (Fifth disease, Slapped cheek disease)
• Exanthem of primary HIV infection (Acute retroviral syndrome)
• Farmyard pox
  Farmyard pox
  Farmyard pox is a group of closely related parapoxviruses of sheep and cattle that cause similar diseases in humans. Conditions included in this group are:* Milker's nodule* Bovine papular stomatitis* Pseudocowpox...
  
  
• Generalized vaccinia
  Generalized vaccinia
  Generalized vaccinia is a cutaneous condition that occurs 6-9 days after vaccination, characterized by a generalized eruption of skin lesions, and caused by the vaccinia virus....
  
  
• Genital herpes (Herpes genitalis, Herpes progenitalis)
• Gianotti–Crosti syndrome (Infantile papular acrodermatitis, Papular acrodermatitis of childhood, Papulovesicular acrolocated syndrome)
• Giant condyloma acuminatum
  Giant condyloma acuminatum
  Giant condyloma acuminatum is a rare cutaneous condition characterized by an aggressive, wart-like growth that is a verrucous carcinoma. It is attributed to human papillomavirus....
  
   (Buschke–Löwenstein tumor)
• Hand-foot-and-mouth disease
• Heck's disease
  Heck's disease
  Heck's disease is a cutaneous condition characterized by white to pinkish papules that occur diffusely in the oral cavity. It is caused by the human papilloma virus types 13 and 32.- References :...
  
   (Focal epithelial hyperplasia)
• Hemorrhagic fever with renal syndrome
• Hepatitis B
• Hepatitis C
  Hepatitis C
  Hepatitis C is an infectious disease primarily affecting the liver, caused by the hepatitis C virus . The infection is often asymptomatic, but chronic infection can lead to scarring of the liver and ultimately to cirrhosis, which is generally apparent after many years...
  
  
• Herpangina
  Herpangina
  Herpangina, also called mouth blisters, is the name of a painful mouth infection caused by coxsackieviruses. Usually, herpangina is produced by one particular strain of coxsackie virus A but it can also be caused by coxsackievirus B or echoviruses. Most cases of herpangina occur in the summer,...
  
  
• Herpes gladiatorum (Scrum pox)
• Herpes simplex
  Herpes simplex
  Herpes simplex is a viral disease caused by both Herpes simplex virus type 1 and type 2 . Infection with the herpes virus is categorized into one of several distinct disorders based on the site of infection. Oral herpes, the visible symptoms of which are colloquially called cold sores or fever...
  
  
• Herpes zoster oticus (Ramsay–Hunt syndrome)
• Herpetic keratoconjunctivitis
• Herpetic sycosis
  Herpetic sycosis
  Herpetic sycosis is a recurrent or initial herpes simplex infection affecting primarily the hair follicle....
  
  
• Herpetic whitlow
  Herpetic whitlow
  A herpetic whitlow is a lesion on a finger or thumb caused by the herpes simplex virus. It is a painful infection that typically affects the fingers or thumbs. Occasionally infection occurs on the toes or on the nail cuticle. Herpes whitlow can be caused by infection by HSV-1 or HSV-2...
  
  
• HIV-associated pruritus
  HIV-associated pruritus
  HIV-associated pruritus is a cutaneous condition, an itchiness of the skin, that occurs in up to 30% of HIV infected people, occurs when the T-cell count drops below 400 per cubic mm....
  
  
• Human monkeypox
• Human T-lymphotropic virus 1 infection
• Human tanapox
• Immune reconstitution inflammatory syndrome
  Immune reconstitution inflammatory syndrome
  Immune reconstitution inflammatory syndrome is a condition seen in some cases of AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the...
  
   (Immune recovery syndrome)
• Infectious mononucleosis
  Infectious mononucleosis
  Infectious mononucleosis is an infectious, widespread viral...
  
   (Glandular fever)
• Inflammatory skin lesions following zoster infection
  Inflammatory skin lesions following zoster infection
  Inflammatory skin lesions following zoster infection is a cutaneous condition that may occur following zoster, characterized by skin lesions within the affected dermatome....
  
   (Isotopic response)
• Intrauterine herpes simplex 
  
• Kaposi sarcoma
• Lassa fever
  Lassa fever
  Lassa fever is an acute viral hemorrhagic fever caused by the Lassa virus and first described in 1969 in the town of Lassa, in Borno State, Nigeria, in the Yedseram river valley at the south end of Lake Chad. Clinical cases of the disease had been known for over a decade but had not been connected...
  
  
• Lipschütz ulcer
  Lipschütz ulcer
  Lipschütz ulcer or ulcus vulvae acutum is a rare disease characterized by painful genital ulcers, fever, and lymphadenopathy, occurring most commonly in adolescents and young women...
  
   (Ulcus vulvae acutum)
• Measles
  Measles
  Measles, also known as rubeola or morbilli, is an infection of the respiratory system caused by a virus, specifically a paramyxovirus of the genus Morbillivirus. Morbilliviruses, like other paramyxoviruses, are enveloped, single-stranded, negative-sense RNA viruses...
  
   (Rubeola, Morbilli)
• Milker's nodule
  Milker's nodule
  Milker's nodules are a cutaneous condition that is most commonly transmitted from the udders of infected cows.. Milker's nodule is caused by Paravaccinia virus. Disease in humans is nearly identical to orf....
  
  
• Modified varicella-like syndrome
  Modified varicella-like syndrome
  Modified varicella-like syndrome is a cutaneous condition that occurs in children immunized with live attenuated varicella vaccine which may cause a varicella of reduced severity upon exposure to natural varicella virus....
  
  
• Molluscum contagiosum
  Molluscum contagiosum
  Molluscum contagiosum is a viral infection of the skin or occasionally of the mucous membranes. It is caused by a DNA poxvirus called the molluscum contagiosum virus . MCV has no animal reservoir, infecting only humans. There are four types of MCV, MCV-1 to -4; MCV-1 is the most prevalent and...
  
  
• Neonatal herpes simplex
  Neonatal herpes simplex
  Neonatal herpes simplex is a rare but serious condition, usually caused by vertical transmission of herpes simplex virus from mother to newborn.-Transmission:...
  
  
• Ophthalmic zoster
  Ophthalmic zoster
  Ophthalmic zoster is a cutaneous condition, a specific type of herpes zoster affecting the ophthalmic division of the fifth cranial nerve.- See also :* Disseminated herpes zoster* Inflammatory skin lesions following zoster infection...
  
  
• Orf
  Orf (disease)
  Orf is an exanthemous disease caused by a parapox virus and occurring primarily in sheep and goats. It is also known as contagious pustular dermatitis, infectious labial dermatitis, ecthyma contagiosum, and sheep pox, thistle disease and scabby mouth...
  
   (Contagious pustular dermatosis, Ecthyma contagiosum, Infectious labial dermatitis, Sheep pox)
• Orolabial herpes (Herpes labialis)
• Papular purpuric gloves and socks syndrome
  Papular purpuric gloves and socks syndrome
  Papular purpuric gloves and socks syndrome is a cutaneous condition characterized by pruritus, edema, and erythema of the hands and feet, occurring primarily in teenagers and young adults.An association with parvovirus B19 has been described....
  
  
• Pigmented wart
  Pigmented wart
  Pigmented warts are a cutaneous condition commonly reported in Japan, most often occurring on the hands or feet....
  
  
• Postherpetic neuralgia
  Postherpetic neuralgia
  Postherpetic neuralgia is a neuralgia caused by the varicella zoster virus. Typically, the neuralgia is confined to a dermatomic area of the skin and follows an outbreak of herpes zoster in that same dermatomic area...
  
   (Zoster-associated pain)
• Post-vaccination follicular eruption
  Post-vaccination follicular eruption
  Post-vaccination follicular eruption is a cutaneous condition that occurs 9 to 11 days following vaccination, and is characterized in multiple follicular, erythematous papules....
  
  
• Progressive vaccinia
  Progressive vaccinia
  Progressive vaccinia is a rare cutaneous condition caused by the vaccinia virus, characterized by painless, but progressive, necrosis and ulceration....
  
   (Vaccinia gangrenosum, Vaccinia necrosum)
• Pseudocowpox
  Pseudocowpox
  Pseudocowpox is a disease caused by Pseudocowpox virus, a virus of the family Poxviridae and the genus Parapoxvirus. Pseudocowpox is a worldwide disease of cattle. Symptoms include ring or horseshoe shaped scabs on the teats, which usually heal within six weeks. Lesions may also develop on the...
  
  
• Rabies
  Rabies
  Rabies is a viral disease that causes acute encephalitis in warm-blooded animals. It is zoonotic , most commonly by a bite from an infected animal. For a human, rabies is almost invariably fatal if post-exposure prophylaxis is not administered prior to the onset of severe symptoms...
  
  
• Recurrent respiratory papillomatosis (Laryngeal papillomatosis)
• Rift Valley fever
  Rift Valley fever
  Rift Valley Fever is a viral zoonosis causing fever. It is spread by the bite of infected mosquitoes, typically the Aedes or Culex genera. The disease is caused by the RVF virus, a member of the genus Phlebovirus...
  
  
• Roseola infantum (Exanthem subitum, Exanthema subitum, Sixth disease)
• Roseola vaccinia
  Roseola vaccinia
  Roseola vaccinia is a cutaneous condition characterized by a prominent rim of erythema surround the site of vaccination injection....
  
  
• Rubella
  Rubella
  Rubella, commonly known as German measles, is a disease caused by the rubella virus. The name "rubella" is derived from the Latin, meaning little red. Rubella is also known as German measles because the disease was first described by German physicians in the mid-eighteenth century. This disease is...
  
   (German measles)
• Sandfly fever
  Pappataci fever
  Pappataci fever is a vector-borne febrile arboviral infection caused by three serotypes of Phlebovirus. Occurs in subtropical regions of the Eastern Hemisphere...
  
   (Pappataci fever, Phlebotomus fever)
• Sealpox
  Sealpox
  Sealpox is a cutaneous condition caused by parapoxvirus, usually affecting seal handlers who have been bitten by infected harbor or grey seals....
  
  
• Varicella (Chickenpox)
• Variola major (Smallpox)
• Verruca plana
  Verruca plana
  Verruca plana, also known as a "flat wart", is a reddish-brown or flesh-colored, slightly raised, flat-surfaced, well-demarcated papule of 2 to 5 mm in diameter. Upon close inspection, these lesions have a surface that is "finely verrucous". Most often, these lesions affect the hands or...
  
   (Flat warts)
• Verruca plantaris (Plantar wart)
• Verruca vulgaris (Wart)
• Verrucae palmares et plantares
  Verrucae palmares et plantares
  Verrucae palmares et plantares is a cutaneous condition characterized by warts on the palms and soles.They are very contagious, and spread easily. Dry ice or liquid Nitrogen can get rid of them.- References :...
  
  
• Viral-associated trichodysplasia
  Viral-associated trichodysplasia
  Viral-associated trichodysplasia is a rare cutaneous condition that occasionally occurs with organ transplant patients on immunosuppressive regimens, characterized by erythematous 1- to 3-mm facial papules.A new human polyomavirus was recently discovered and identified...
  
   (Ciclosporin-induced folliculodystrophy)
• Wasting syndrome
• West Nile virus infection
• Zoster (Herpes zoster, Shingles)
• Zoster sine herpete

Lichenoid eruptions

Lichenoid eruptions are dermatoses related to the unique, common inflammatory

Inflammation

Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...

 disorder lichen planus

Lichen planus

Lichen planus is a chronic mucocutaneous disease that affects the skin, tongue, and oral mucosa. The disease presents itself in the form of papules, lesions, or rashes. Lichen planus does not involve lichens, the fungus/algae symbionts that often grow on tree trunks; the name refers to the dry and...

, which affects the skin, mucous membrane

Mucous membrane

The mucous membranes are linings of mostly endodermal origin, covered in epithelium, which are involved in absorption and secretion. They line cavities that are exposed to the external environment and internal organs...

s, nails, and hair.

• Annular lichen planus
  Annular lichen planus
  Annular lichen planus occurs in approximately ten percent of lichen planus cases, and commonly develop as arcuate groupings of individual papules that develop rings or peripheral extension of clustered papules with central clearing....
  
  
• Atrophic lichen planus
  Atrophic lichen planus
  Atrophic lichen planus is a rare variant of lichen planus, and characterized by the presence of a few well-demarcated, white-bluish papules or plaques with central superficial atrophy....
  
  
• Bullous lichen planus
  Bullous lichen planus
  Bullous lichen planus is a rare variant of lichen planus, characterized by the development of vesicles and bullae with the skin lesions....
  
   (Vesiculobullous lichen planus)
• Erythema dyschromicum perstans
  Erythema dyschromicum perstans
  Erythema dyschromicum perstans is a skin condition with age of onset almost always before 40 years old, characterized by skin lesions that are usually symmetrical and generalized....
  
   (Ashy dermatosis, Dermatosis cinecienta)
• Giant cell lichenoid dermatitis
  Giant cell lichenoid dermatitis
  Giant cell lichenoid dermatitis is a cutaneous condition usually drug-associated entity, characterized by a lichenoid dermatitis with a granulomatous infiltrate composed of histiocytes and multinucleated giant cells....
  
  
• Hepatitis-associated lichen planus
  Hepatitis-associated lichen planus
  Hepatitis-associated lichen planus is a skin condition that has been associated with three liver conditions: hepatitis C viral infection, hepatitis B immunization, and primary biliary cirrhosis....
  
  
• Hypertrophic lichen planus
  Hypertrophic lichen planus
  Hypertrophic lichen planus usually occurs on the extremities, especially the shin and interphalangeal joints, and tends to be the most pruritic variant of lichen planus....
  
   (Lichen planus verrucosus)
• Idiopathic eruptive macular pigmentation
  Idiopathic eruptive macular pigmentation
  Idiopathic eruptive macular pigmentation is a skin condition developing in young persons, with an average age of 11, characterized by asymptomatic widespread brown to gray macules of up to several centimeters in diameter on the neck, trunk, and proximal extremities....
  
  
• Inverse lichen planus
  Inverse lichen planus
  Inverse lichen planus is a variant of lichen planus characterized by violaceous papules and plaques appear in intertriginous areas of the skin....
  
  
• Keratosis lichenoides chronica
  Keratosis lichenoides chronica
  Keratosis lichenoides chronica is a rare dermatosis characterized by violaceous papular and nodular lesions, often arranged in a linear or reticulate pattern on the dorsal hands and feet, extremities, and buttock....
  
   (Nékam's disease)
• Kraurosis vulvae
  Kraurosis vulvae
  Kraurosis vulvae is a cutaneous condition characterized by atrophy and shrinkage of the skin of the vagina and vulva often accompanied by a chronic inflammatory reaction in the deeper tissues....
  
  
• Lichen nitidus
  Lichen nitidus
  Lichen nitidus is a chronic inflammatory disease of unknown etiology characterized by 1-2 mm, discrete and uniform, shiny, flat-topped, pale flesh-colored or reddish-brown papules that may appear as hypopigmented against dark skin. Occasionally, minimal scaling is present or can be induced by...
  
  
• Lichen planus actinicus
  Lichen planus actinicus
  Lichen planus actinicus is a variant of lichen planus that is more common in Middle Eastern countries in spring and summer,...
  
   (Actinic lichen niditus, Actinic lichen planus, Lichen planus atrophicus annularis, Lichen planus subtropicus, Lichen planus tropicus, Lichenoid melanodermatitis, Lichenoid melanodermatosis, Summertime actinic lichenoid eruption)
• Lichen planus pemphigoides
  Lichen planus pemphigoides
  Lichen planus pemphigoides is characterized by the development of tense blisters atop lesions of lichen planus or the development vesicles de novo on uninvolved skin...
  
  
• Lichen planus pigmentosus
  Lichen planus pigmentosus
  Lichen planus pigmentosus is an uncommon variant of lichen planus characterized by hyperpigmented, dark-brown macules in sun-exposed areas and flexural folds....
  
  
• Lichen planus–lichen sclerosus overlap syndrome
• Lichen ruber moniliformis
• Lichen sclerosus
  Lichen sclerosus
  Lichen sclerosus is an uncommon disease of unknown cause that results in white patches on the skin, which may cause scarring on and around genital skin....
  
   (Lichen sclerosus et atrophicus)
• Lichen striatus
  Lichen striatus
  Lichen striatus is a rare skin condition that is seen primarily in children, most frequently appearing ages 5-15....
  
   (Blaschko linear acquired inflammatory skin eruption, Linear lichenoid dermatosis)
• Lichen verrucosus et reticularis
  Lichen verrucosus et reticularis
  Lichen verrucosus et reticularis is a cutaneous condition that may be related to keratosis lichenoides chronica....
  
  
• Lichenoid trikeratosis
  Lichenoid trikeratosis
  Lichenoid trikeratosis is a cutaneous condition that may be related to keratosis lichenoides chronica....
  
  
• Lichenoid dermatitis
  Lichenoid dermatitis
  Lichenoid dermatitis represents a wide range of cutaneous disorders characterized by lichen planus-like skin lesions....
  
  
• Lichenoid reaction of graft-versus-host disease
  Lichenoid reaction of graft-versus-host disease
  Lichenoid reaction of graft-versus-host disease presents with chronic graft-versus-host disease, characterized by a lichenoid eruption indistinguishable clinically and histologically from lichen planus. This type of lichenoid lesions have a higher risk of malignant transformation to oral squamous...
  
  
• Linear lichen planus
  Linear lichen planus
  Linear lichen planus may develop secondary to trauma or, uncommonly, as a spontaneous, isolated eruption, usually on the extremities, and rarely on the face....
  
  
• Peno-gingival syndrome
  Peno-gingival syndrome
  Peno-gingival syndrome is a cutaneous condition, the equivalent of vulvovaginal gingival syndrome, but in men....
  
  
• Ulcerative lichen planus
  Ulcerative lichen planus
  Ulcerative lichen planus is a rare variant of lichen planus presenting with chronic, painful bullae and ulceration of the feet, often with cicatricial sequelae evident....
  
  
• Vulvovaginal gingival syndrome
  Vulvovaginal gingival syndrome
  Vulvovaginal gingival syndrome is a cutaneous condition characterized by lichen planus of the vulva, vagina, and gingiva....
  
  
• Vulvovaginal lichen planus

Lymphoid-related

Lymphoid-related cutaneous conditions are a group of disorders characterized by collections of lymphocyte

Lymphocyte

A lymphocyte is a type of white blood cell in the vertebrate immune system.Under the microscope, lymphocytes can be divided into large lymphocytes and small lymphocytes. Large granular lymphocytes include natural killer cells...

 cells within the skin.

• Adult T-cell leukemia/lymphoma
• Angiocentric lymphoma
  Angiocentric lymphoma
  Angiocentric lymphoma is a cutaneous condition which in Korea, is reported to be the most common form of cutaneous lymphoma after mycosis fungoides.Extranodal NK-T-cell lymphoma is a type of lymphoma.It is called "extranodal" to...
  
   (Extranodal natural killer cell lymphoma, Nasal-type NK lymphoma, NK/T-cell lymphoma, Polymorphic/malignant midline reticulosis)
• Angioimmunoblastic T-cell lymphoma
  Angioimmunoblastic T-cell lymphoma
  Angioimmunoblastic T-cell lymphoma is a mature T-cell lymphoma with systemic characterized by a polymorphous lymph node infiltrate showing a marked increase in follicular dendritic cells and high endothelial venules and systemic involvement...
  
    (Angioimmunoblastic lymphadenopathy with dysproteinemia)
• Blastic NK-cell lymphoma
  Blastic NK-cell lymphoma
  Blastic NK-cell lymphoma is a cutaneous condition characterized by multiple, rapidly expanding plaques....
  
  
• CD30+ cutaneous T-cell lymphoma
  CD30+ cutaneous T-cell lymphoma
  CD30+ cutaneous T-cell lymphoma is a cutaneous condition characterized by solitary of localized skin lesions that have a tendency to ulcerate.- See also :* Cutaneous T-cell lymphoma...
  
   (Primary cutaneous anaplastic large cell lymphoma)
• Cutaneous lymphoid hyperplasia
  Cutaneous lymphoid hyperplasia
  Cutaneous lymphoid hyperplasia refers to a groups of benign cutaneous disorders characterized by collections of lymphocytes,...
  
   (Borrelial lymphocytoma, Lymphadenosis benigna cutis, Lymphocytoma cutis, Pseudolymphoma, Pseudolymphoma of Spiegler and Fendt, Sarcoidosis of Spiegler and Fendt, Spiegler–Fendt lymphoid hyperplasia, Spiegler–Fendt sarcoid)
• Cutaneous lymphoid hyperplasia with bandlike and perivascular patterns
  Cutaneous lymphoid hyperplasia with bandlike and perivascular patterns
  Cutaneous lymphoid hyperplasia with bandlike and perivascular patterns is a condition of the skin characterized by skin lesions that clinically resemble mycosis fungoides....
  
  
• Cutaneous lymphoid hyperplasia with nodular pattern
  Cutaneous lymphoid hyperplasia with nodular pattern
  Cutaneous lymphoid hyperplasia with nodular pattern is a condition of the skin characterized by a solitary or localized cluster of asymptomatic erythematous to violaceous papules or nodules....
  
   (Nodular pattern of cutaneous lymphoid hyperplasia)
• Diffuse large B-cell lymphoma (Primary cutaneous large B-cell lymphoma)
• Granulocytic sarcoma
  Granulocytic sarcoma
  A myeloid sarcoma , is a solid tumor composed of immature white blood cells called myeloblasts...
  
   (Chloroma, Myeloid sarcoma)
• Granulomatous slack skin
  Granulomatous slack skin
  Granulomatous slack skin is a rare cutaneous condition, a variant of lymphoma that typically presents in middle aged adults.It is a form of cutaneous T-cell lymphoma.It is a variant of mycosis fungoides....
  
  
• Hairy-cell leukemia
• Hodgkin's disease
• Ichthyosis acquisita
  Ichthyosis acquisita
  Ichthyosis acquisita is a disorder clinically and histologically similar to ichthyosis vulgaris.-Associated conditions:...
  
   (Acquired ichthyosis)
• Intravascular large B-cell lymphoma
  Intravascular large B-cell lymphoma
  Intravascular large B-cell lymphoma, abbreviated ILBCL and also referred to as angiotropic large-cell lymphoma, intralymphatic lymphomatosis, intravascular lymphomatosis,, and, less specifically intravascular lymphoma.-Diagnosis:...
  
   (Angiotropic large cell lymphoma, Intralymphatic lymphomatosis, Intravascular lymphomatosis, Malignant angioendotheliomatosis)
• Jessner lymphocytic infiltrate of the skin
  Jessner lymphocytic infiltrate of the skin
  Jessner lymphocytic infiltrate of the skin is a cutaneous condition characterized by a persistent papular and plaque-like skin eruption.Thought to occur on the neck, face and back and...
  
   (Benign lymphocytic infiltration of the skin, Jessner lymphocytic infiltration of the skin, Jessner–Kanof lymphocytic infiltration of the skin, Lymphocytic infiltrate of Jessner)
• Kikuchi's disease (Histiocytic necrotizing lymphadenitis)
• Large plaque parapsoriasis (Parapsoriasis en plaques)
• Lennert lymphoma
  Lennert lymphoma
  Lennert lymphoma is a systemic T-cell lymphoma that presents with cutaneous skin lesions roughly 10% of the time.It is also known as "lymphoepithelioid variant of peripheral T-cell lymphoma"....
  
   (Lymphoepitheliod lymphoma)
• Leukemia cutis
  Leukemia cutis
  Leukemia cutis is the infiltration of neoplastic leukocytes or their precursors into the skin resulting in clinically identifiable cutaneous lesions...
  
  
• Lymphoma cutis
• Lymphomatoid granulomatosis
  Lymphomatoid granulomatosis
  Lymphomatoid granulomatosis is a neoplastic disease.It is a lymphoproliferative disorder . The word granulomatosis denotes one of its microscopic character, polymorphic lymphoid infiltrates and focal necrosis within it....
  
  
• Lymphomatoid papulosis
  Lymphomatoid papulosis
  Lymphomatoid papulosis is a rare skin disorder. The overall prevalence rate of lymphomatoid papulosis is estimated at 1.2 to 1.9 cases per 1,000,000 population.This rare condition has only been studied in depth since 1968.-Presentation:...
  
  
• Malignant histiocytosis
  Malignant histiocytosis
  Malignant histiocytosis is a rare hereditary disease found in the Bernese Mountain Dog and humans, characterized by histiocytic infiltration of the lungs and lymph nodes. The liver, spleen, and central nervous system can also be affected. Histiocytes are a component of the immune system that...
  
   (Histiocytic medullary reticulosis)
• Marginal zone B-cell lymphoma
  Marginal zone B-cell lymphoma
  Marginal zone B-cell lymphoma is a type of B-cell lymphoma presenting primarily in the marginal zone.There are three types:* Splenic marginal zone lymphoma* Extranodal marginal zone B cell lymphoma...
  
  
• Mucosa-associated lymphoid tissue lymphoma
• Mycosis fungoides
  Mycosis fungoides
  -External links:* * *...
  
  
• Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
  Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
  Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma is a cutaneous condition that usually presents as solitary or generalized plaques, nodules, or tumors of short duration.- See also :* Cutaneous T-cell lymphoma* CD30+ cutaneous T-cell lymphoma...
  
  
• Nonspecific cutaneous conditions associated with leukemia (Leukemid)
• Pagetoid reticulosis
  Pagetoid reticulosis
  Pagetoid reticulosis is a cutaneous condition, an uncommon lymphoproliferative disorder, sometimes considered a form of mycosis fungoides....
  
   (Acral mycoses fungoides, Localized epidermotropic reticulosis, Mycosis fungoides palmaris et plantaris, Unilesional mycosis fungoides, Woringer–Kolopp disease)
• Pityriasis lichenoides chronica
  Pityriasis lichenoides chronica
  Pityriasis lichenoides chronica is an uncommon, idiopathic, acquired dermatosis, characterized by evolving groups of erythematous, scaly papules that may persist for months.- Causes :Pityriasis...
  
   (Chronic guttate parapsoriasis, Chronic pityriasis lichenoides, Dermatitis psoriasiformis nodularis, Parapsoriasis chronica, Parapsoriasis lichenoides chronica)
• Pityriasis lichenoides et varioliformis acuta
  Pityriasis lichenoides et varioliformis acuta
  Pityriasis lichenoides et varioliformis acuta is a disease of the immune system. It is the more severe version of Pityriasis lichenoides chronica...
  
   (Acute guttate parapsoriasis, Acute parapsoriasis, Acute pityriasis lichenoides, Mucha–Habermann disease, Parapsoriasis acuta, Parapsoriasis lichenoides et varioliformis acuta, Parapsoriasis varioliformis)
• Plasmacytoma
  Plasmacytoma
  Plasmacytoma refers to a malignant plasma cell tumor growing within soft tissue or within the skeleton. The skeletal forms usually have other occult tumors and frequently disseminate to multiple myeloma over the course of 5–10 years. The soft tissue forms most often occur in the upper respiratory...
  
   
• Plasmacytosis
  Plasmacytosis
  Plasmacytosis is a condition in which there is an unusually large proportion of plasma cells in tissues, exudates, or blood. Plasmacytosis may be divided into two types—cutaneous and systemic—both of which have identical skin findings....
  
  
• Pleomorphic T-cell lymphoma
  Pleomorphic T-cell lymphoma
  Pleomorphic T-cell lymphoma is a cutaneous condition characterized by a 5-year survival rate of 62%.- See also :* Cutaneous T-cell lymphoma...
  
   (Non-mycosis fungoides CD30− pleomorphic small/medium sized cutaneous T-cell lymphoma)
• Polycythemia vera
  Polycythemia vera
  Polycythemia vera is a blood disorder in which the bone marrow makes too many red blood cells. It may also result in the overproduction of white blood cells and platelets. Most of the health concerns associated with polycythemia vera are caused by the blood being thicker as a result of the...
  
   (Erythremia)
• Primary cutaneous follicular lymphoma
  Primary cutaneous follicular lymphoma
  Primary cutaneous follicular lymphoma is a cutaneous condition characterized by single or multiple papules, plaques or nodules with surrounding erythema.- See also :...
  
   (Follicular center cell lymphoma, Follicular center lymphoma)
• Primary cutaneous immunocytoma
  Primary cutaneous immunocytoma
  Primary cutaneous immunocytoma is a skin condition that represents a low grade B-cell lymphoma related to marginal zone B-cell lymphoma but with a predominance of cells having plasmacytic features....
  
  
• Primary cutaneous marginal zone lymphoma
  Primary cutaneous marginal zone lymphoma
  Primary cutaneous marginal zone lymphomas represent a heterogeneous group of diseases characterized by solitary or multiple dermal or subcutaneous nodules. Lymphomas included in this group are:* Primary cutaneous immunocytoma* Marginal zone B-cell lymphoma...
  
  
• Retiform parapsoriasis
  Retiform parapsoriasis
  Retiform parapsoriasis is a cutaneous condition, considered to be a type of large-plaque parapsoriasis. It is characterized by widespread, ill-defined plaques on the skin, that have a net-like or zebra-striped pattern...
  
  
• Secondary cutaneous CD30+ large cell lymphoma
  Secondary cutaneous CD30+ large cell lymphoma
  Secondary cutaneous CD30+ large-cell lymphoma is a cutaneous condition that may arise in cases of mycosis fungoides, and in patients with lymphomatoid papulosis.- See also :* Cutaneous T-cell lymphoma* CD30+ cutaneous T-cell lymphoma* Skin lesion...
  
  
• Sézary syndrome
• Sinus histiocytosis with massive lymphadenopathy (Rosai–Dorfman disease)
• Subcutaneous T-cell lymphoma
  Subcutaneous T-cell lymphoma
  Subcutaneous T-cell lymphoma is a cutaneous condition that most commonly presents in young adults, and is characterized by subcutaneous nodules.-Classification:...
  
   (Panniculitis-like T-cell lymphoma)
• Vesiculopustular eruption and leukemoid reaction in Down syndrome
  Vesiculopustular eruption and leukemoid reaction in Down syndrome
  Vesiculopustular eruption and leukemoid reaction in Down syndrome is a cutaneous condition, an extensive neonatal vesiculopustular eruption seen in patients with Down syndrome....
  
  

Melanocytic nevi and neoplasms

Melanocytic nevi and neoplasms are caused by either a proliferation of (1) melanocyte

Melanocyte

-External links: - "Eye: fovea, RPE" - "Integument: pigmented skin"...

s, or (2) nevus cell

Nevus cell

Nevus cells are a variant of melanocytes. They are larger than typical melanocytes, do not have dendrites, and have more abundant cytoplasm with coarse granules. They are usually located at the dermoepidermal junction or in the dermis of the skin...

s, a form of melanocyte that lack dendritic processes.

• Acral nevus
  Acral nevus
  An Acral nevus is a cutaneous condition characterized by a skin lesion that is usually macular or only slightly elevated, and may display uniform brown or dark brown color, but often with linear striations....
  
   (Melanocytic nevus of acral skin, Melanocytic nevus with intraepidermal ascent of cells)
• Amelanotic blue nevus
  Amelanotic blue nevus
  An Amelanotic blue nevus is a cutaneous condition characterized by mild atypia and pleomorphism....
  
   (Hypomelanotic blue nevus)
  
• Balloon cell nevus
  Balloon cell nevus
  Balloon cell nevi are a cutaneous condition characterized histologically by large, pale, polyhedral balloon cells....
  
  
• Bannayan–Riley–Ruvalcaba syndrome
• Becker's nevus
  Becker's nevus
  Becker's nevus is a skin disorder predominantly affecting males...
  
   (Becker's melanosis, Becker's pigmentary hamartoma, Nevoid melanosis, Pigmented hairy epidermal nevus)
• Benign melanocytic nevus
  Benign melanocytic nevus
  A benign melanocytic nevus is a cutaneous condition characterised by well-circumscribed, round or ovoid lesions, generally measuring from 2 to 6 mm in diameter....
  
   (Banal nevus, Common acquired melanocytic nevus, Mole, Nevocellular nevus, Nevocytic nevus)
• Blue nevus
  Blue nevus
  Blue nevus is a type of melanocytic nevus.It is usually described as non-cancerous, but can be malignant.- Types :Blue nevi may be divided into the following types:...
  
   (Blue neuronevus, Dermal melanocytoma, Nevus bleu)
• Blue nevus of Jadassohn–Tièche (Common blue nevus, Nevus ceruleus)
• Carney complex
  Carney complex
  Carney complex, also known as LAMB syndrome and NAME syndrome is an autosomal dominant condition comprising myxomas of the heart and skin, hyperpigmentation of the skin , and endocrine overactivity It is distinct from Carney's triad...
  
   (LAMB syndrome, NAME syndrome)
• Cellular blue nevus
  Cellular blue nevus
  Cellular blue nevi are a cutaneous condition characterized by large, firm, blue or blue-black nodules....
  
  
• Centrofacial lentiginosis
  Centrofacial lentiginosis
  Centrofacial lentiginosis is a cutaneous condition characterized by lentigines on the nose and adjacent cheeks....
  
  
• Congenital melanocytic nevus
  Congenital melanocytic nevus
  The congenital melanocytic nevus is a type of melanocytic nevus found in infants at birth. This type of birthmark occurs in about 1% of infants in the United States; it is located in the area of the head and neck 15% of the time....
  
  
• Deep penetrating nevus
  Deep penetrating nevus
  A deep penetrating nevus is a type of benign melanocytic skin tumor characterized, as its name suggests, by penetration into the deep dermis and/or subcutis. Smudged chromatic is a typical finding. In some cases mitotic figures or atypical melanocytic cytology are seen, potentially mimicking a...
  
  
• Dysplastic nevus
  Dysplastic nevus
  A dysplastic nevus is an atypical melanocytic nevus; a mole whose appearance is different from that of common moles. Dysplastic nevi are generally larger than ordinary moles and have irregular and indistinct borders...
  
   (Atypical mole, Atypical nevus, B-K mole, Clark's nevus, Dysplastic melanocytic nevus, Nevus with architectural disorder)
• Dysplastic nevus syndrome
  Dysplastic nevus syndrome
  Dysplastic nevus syndrome is a cutaneous condition described in certain families, and characterized by unusual nevi and multiple inherited melanomas.-Historical background:In 1820 Norris reported the first case of what is now recognized as FAMMM...
  
   (B-K mole syndrome, Familial atypical multiple mole–melanoma syndrome, Familial melanoma syndrome)
• Ephelis (Freckle)
• Epithelioid blue nevus
  Epithelioid blue nevus
  Epithelioid blue nevi are a cutaneous condition most commonly seen in patients with the Carney complex....
  
  
• Generalized lentiginosis
  Generalized lentiginosis
  Generalized lentiginosis is a cutaneous condition that will occasionally present without other associated abnormalities. It may be caused by carney complex, LEOPARD syndrome or Peutz–Jeghers syndrome....
  
  
• Giant pigmented nevus
  Giant pigmented nevus
  Giant pigmented nevus is a cutaneous condition characterized by a large, darkly pigmented hairy patches....
  
   (Bathing trunk nevus, Congenital nevomelanocytic nevus, Garment nevus, Giant hairy nevus, Nevus pigmentosus et pilosus)
• Halo nevus
  Halo nevus
  Halo nevus is a mole that is surrounded by a depigmented ring or 'halo'.-Causes:Halo nevi are caused when white blood cells target a mole...
  
   (Leukoderma acquisitum centrifugum, Perinevoid vitiligo, Sutton nevus)
• Hori's nevus
  Hori's nevus
  Hori's nevus is a cutaneous condition characterized by multiple brown–gray to brown–blue macules, primarily in the malar region of the face....
  
   (Acquired bilateral nevus of Ota-like macules)
• Inherited patterned lentiginosis in black persons
  Inherited patterned lentiginosis in black persons
  Inherited patterned lentiginosis in black persons is a cutaneous condition inherited in an autosomal dominant fashion, presenting in infancy or early childhood....
  
  
• Ink spot lentigo
  Ink spot lentigo
  Ink spot lentigo is a cutaneous condition characterized by skin lesions commonly occurring on the shoulders....
  
   (Sunburn lentigo)
• Laugier–Hunziker syndrome
  Laugier–Hunziker syndrome
  Laugier–Hunziker syndrome is a cutaneous condition characterized by longitudinal melanonychia and genital melanosis....
  
  
• Lentigo simplex
  Lentigo simplex
  Lentigo simplex is the most common form of lentigo. A single lesion or multiple lesions may be present at birth or more commonly first develop in early childhood. Lentigo simplex is not induced by sun exposure, and it is not associated with any medical diseases or conditions...
  
   (Simple lentigo)
• Malignant blue nevus
  Malignant blue nevus
  A malignant blue nevus is a cutaneous condition characterized by a sheet-like growth pattern, mitoses, necrosis, and cellular atypia....
  
  
• Medium-sized congenital nevocytic nevus
  Medium-sized congenital nevocytic nevus
  Medium-sized congenital nevocytic nevus is a cutaneous condition characterized by a nevus, generally defined as having a diameter more than 2cm but less than 20cm.- See also :* Congenital melanocytic nevus* Skin lesion* List of cutaneous conditions...
  
  
• Melanoacanthoma
  Melanoacanthoma
  Melanoacanthoma is a common, benign, darkly pigmented cutaneous condition characterized by a skin lesion with a dull or lackluster surface.It involves a proliferation of keratinocytes and melanocytes....
  
  
• Melanocytic tumors of uncertain malignant potential
  Melanocytic tumors of uncertain malignant potential
  Melanocytic tumors of uncertain malignant potential are melanocytic lesions in the dermis that cannot be classified by morphology as either benign naevi or malignant melanomas because the mass shows features of both....
  
  
• Moynahan syndrome
  Moynahan syndrome
  Moynahan syndrome is a cutaneous condition characterized by multiple lentigines, congenital mitral stenosis, dwarfism, genital hypoplasia, and mental deficiency.It was characterized in 1962.It is one of three conditions named for Edmund John Moynahan....
  
  
• Mucosal lentigines
  Mucosal lentigines
  Mucosal lentigines is a cutaneous condition characterized by light brown macules on mucosal surfaces....
  
   (Labial and penile and vulvar melanosis, Melanotic macules)
• Nevus of Ito
  Nevus of Ito
  Nevus of Ito is a cutaneous condition with similar features to the Nevus of Ota, but occurring in a different distribution....
  
   (Nevus fuscoceruleus acromiodeltoideus)
• Nevus of Ota
  Nevus of Ota
  Nevus of Ota is a blue hyperpigmentation that occurs on the face. It was first reported by Dr. M. T. Ota of Japan in 1939.Nevus of Ota is caused by the entrapment of melanocytes in the upper third of the dermis...
  
   (Congenital melanosis bulbi, Melanosis bulborum and aberrant dermal melanocytosis, Nevus fuscoceruleus ophthalmomaxillaris, Oculodermal melanocytosis, Oculomucodermal melanocytosis)
• Nevus spilus
  Nevus spilus
  Nevus spilus is a skin lesion that presents as a light brown or tan macule, speckled with smaller, darker macules or papules.- See also :* Phakomatosis pigmentokeratotica...
  
   (Speckled lentiginous nevus, Zosteriform lentiginous nevus)
• Partial unilateral lentiginosis
  Partial unilateral lentiginosis
  Partial unilateral lentiginosis is a cutaneous condition characterized by lentigines located on only one half of the body....
  
   (Segmental lentiginosis)
• Peutz–Jeghers syndrome
• Pigmented spindle cell nevus
  Pigmented spindle cell nevus
  A pigmented spindle cell nevus is a cutaneous condition characterized by a dark brown to black macule or papule, usually less than 6 mm....
  
   (Pigmented spindle cell tumor of Reed, Pigmented variant of Spitz nevus)
• Pseudomelanoma
  Pseudomelanoma
  Pseudomelanoma is a cutaneous condition in which melantic skin lesions clinically resemble a superficial spreading melanoma at the site of a recent shave removal of a melanocytic nevus....
  
   (Recurrent melanocytic nevus, Recurrent nevus)
• PUVA lentigines
• Small-sized congenital nevocytic nevus
  Small-sized congenital nevocytic nevus
  Small-sized congenital nevocytic nevus is a cutaneous condition characterized by a nevus, generally defined as having a diameter less than 2cm....
  
  
• Spitz nevus
  Spitz nevus
  A Spitz nevus is a benign melanocytic nevus, a type of skin lesion, affecting the epidermis and dermis....
  
   (Benign juvenile melanoma, Epithelioid and spindle cell nevus, Spitz's juvenile melanoma)
• Solar lentigo (Lentigo senilis, Liver spot, Old age spot, Senile freckle)

Melanoma

Melanoma

Melanoma

Melanoma is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye...

 is a malignant

Malignant

Malignancy is the tendency of a medical condition, especially tumors, to become progressively worse and to potentially result in death. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis...

 proliferation of melanocytes and the most aggressive type of skin cancer.

• Acral lentiginous melanoma
  Acral lentiginous melanoma
  Acral lentiginous melanoma is a kind of lentiginous skin cancer skin melanoma.Acral lentiginous melanoma is observed on the palms, soles, under the nails and in the oral mucosa. It occurs on non hair-bearing surfaces of the body which may or may not be exposed to sunlight. It is also found on...
  
   
• Amelanotic melanoma
  Amelanotic melanoma
  Amelanotic melanoma is a type of skin cancer in which the cells do not make melanin.appearance: they can be pink,red,purple or of normal skin color, hence difficult to recognise...
  
  
• Animal-type melanoma
  Animal-type melanoma
  Animal-type melanoma is a cutaneous condition and is characterized by nodules and fascicles of epithelioid melanocytes with pleomorphic nuclei and striking hyperpigmentation, dendritic cells, numerous melanophages and, sometimes, an inflammatory infiltrate of lymphocytes....
  
  
• Desmoplastic melanoma
  Desmoplastic melanoma
  Desmoplastic melanoma is a cutaneous condition characterized by a deeply infiltrating type of melanoma....
  
   (Neurotropic melanoma, Spindled melanoma)
• Lentigo maligna
  Lentigo maligna
  Lentigo maligna is a melanoma in situ that consists of malignant cells but does not show invasive growth. Lentigo maligna is not the same as lentigo maligna melanoma, and should be discussed separately. It typically progresses very slowly and can remain in a non-invasive form for years...
  
   (Lentiginous melanoma on sun-damaged skin)
• Lentigo maligna melanoma
  Lentigo maligna melanoma
  Lentigo maligna melanoma is a melanoma that has evolved from a lentigo maligna. They are usually found on chronically sun damaged skin such as the face and the forearms of the elderly. The nomenclature is very confusing to both patients and physicians alike....
  
  
• Melanoma with features of a Spitz nevus
  Melanoma with features of a Spitz nevus
  Melanoma with features of a Spitz nevus is a cutaneous condition characterized histologically with tissue similar to a spitz nevus and with overall symmetry and a dermal nodule of epithelioid melanocytes that do not mature with progressively deeper dermal extension....
  
   (Spitzoid melanoma)
• Melanoma with small nevus-like cells
  Melanoma with small nevus-like cells
  Melanoma with small nevus-like cells is a cutaneous condition, a tumor that contains variably-sized, large nests of small melanocytes with hyperchromatic nuclei and prominent nucleoli....
  
   (Small cell melanoma)
• Mucosal melanoma
  Mucosal melanoma
  Mucosal melanoma is a rare cutaneous condition characterized by a melanoma of the mucous membranes....
  
  
• Nevoid melanoma
  Nevoid melanoma
  Nevoid melanoma is a cutaneous condition that may resemble a Spitz nevus or an acquired or congenital melanocytic nevus....
  
  
• Nodular melanoma
  Nodular melanoma
  Nodular melanoma is the most aggressive form of melanoma. It tends to grow more rapidly in thickness than in diameter. Instead of arising from a pre-existing mole, it may appear in a spot where a lesion did not previously exist...
  
  
• Polypoid melanoma
  Polypoid melanoma
  Polypoid melanoma is a rare cutaneous condition, a virulent variant of nodular melanoma....
  
  
• Soft-tissue melanoma (Clear-cell sarcoma, Melanoma of the soft parts)
• Superficial spreading melanoma
  Superficial spreading melanoma
  Superficial spreading melanoma is usually characterized as the most common form of cutaneous melanoma in Caucasians...
  
   (Superficially spreading melanoma)
• Uveal melanoma
  Uveal melanoma
  Uveal melanoma is a cancer of the eye involving the iris, ciliary body, or choroid . Tumors arise from the pigment cells that reside within the uvea giving color to the eye...
  
  

Monocyte- and macrophage-related

Monocyte- and macrophage-related cutaneous conditions are characterized histologically

Histology

Histology is the study of the microscopic anatomy of cells and tissues of plants and animals. It is performed by examining cells and tissues commonly by sectioning and staining; followed by examination under a light microscope or electron microscope...

 by infiltration

Infiltration (medical)

Infiltration is the diffusion or accumulation of substances not normal to it or in amounts in excess of the normal. The material collected in those tissues or cells is called infiltrate.-Classification:...

 of the skin by monocyte

Monocyte

Monocytes are a type of white blood cell and are part of the innate immune system of vertebrates including all mammals , birds, reptiles, and fish. Monocytes play multiple roles in immune function...

 and/or macrophage

Macrophage

Macrophages are cells produced by the differentiation of monocytes in tissues. Human macrophages are about in diameter. Monocytes and macrophages are phagocytes. Macrophages function in both non-specific defense as well as help initiate specific defense mechanisms of vertebrate animals...

 cells, often divided into several categories, including granulomatous disease, histiocytoses, and sarcoidosis

Sarcoidosis

Sarcoidosis , also called sarcoid, Besnier-Boeck disease or Besnier-Boeck-Schaumann disease, is a disease in which abnormal collections of chronic inflammatory cells form as nodules in multiple organs. The cause of sarcoidosis is unknown...

.

• Actinic granuloma
  Actinic granuloma
  Actinic granuloma is a cutaneous condition characterized histologically by a dermal infiltrate of macrophages.- See also :* Annular elastolytic giant cell granuloma* Skin lesion* List of cutaneous conditions...
  
   (O'Brien granuloma)
• Annular elastolytic giant cell granuloma
  Annular elastolytic giant cell granuloma
  Annular elastolytic giant-cell granuloma is a cutaneous condition characterized histologically by a dermal infiltrate of macrophages.- References :...
  
   (Giant cell elastophagocytosis, Meischer's granuloma, Miescher's granuloma of the face)
• Annular sarcoidosis
  Annular sarcoidosis
  Annular sarcoidosis is a cutaneous condition characterized by papular skin lesions arranged in annular patterns, usually with a red-brown hue....
  
   
• Benign cephalic histiocytosis
  Benign cephalic histiocytosis
  Benign cephalic histiocytosis is a rare cutaneous condition affecting boys and girls equally, characterized by skin lesions that initially present on the head in all cases, often the cheeks, eyelids, forehead, and ears....
  
   (Histiocytosis with intracytoplasmic worm-like bodies)
• Congenital self-healing reticulohistiocytosis
  Congenital self-healing reticulohistiocytosis
  Congenital self-healing reticulohistiocytosis is a condition that is a self-limited form of Langerhans cell histiocytosis....
  
   (Hashimoto–Pritzker disease, Hashimoto–Pritzker syndrome)
• Erythrodermic sarcoidosis
  Erythrodermic sarcoidosis
  Erythrodermic sarcoidosis is a cutaneous condition and very rare form of sarcoidosis....
  
  
• Generalized eruptive histiocytoma
  Generalized eruptive histiocytoma
  Generalized eruptive histiocytoma is a rare cutaneous condition characterized by widespread, erythematous, essentially symmetrical papules, particularly involving the trunk and proximal extremities....
  
   (Eruptive histiocytoma, Generalized eruptive histiocytosis)
• Generalized granuloma annulare
  Generalized granuloma annulare
  Generalized granuloma annulare is a skin condition of unknown cause, tending to affect women in the fifth and sixth decades, presenting as a diffuse but symmetrical, papular or annular eruption of more than ten skin lesions, and often hundreds....
  
  
• Giant cell reticulohistiocytoma (Solitary reticulohistiocytoma, Solitary reticulohistiocytosis)
• Granuloma annulare in HIV disease
  Granuloma annulare in HIV disease
  Granuloma annulare in HIV disease is a skin condition characterized typically by papular and generalized skin lesions.- References :...
  
  
• Granuloma multiforme
  Granuloma multiforme
  Granuloma multiforme is a cutaneous condition most commonly seen in central Africa, and rarely elsewhere, characterized by skin lesions that are on the upper trunk and arms in sun-exposed areas.- References :...
  
   (Leiker)
• Hand–Schüller–Christian disease
• Heerfordt's syndrome
  Heerfordt's syndrome
  Heerfordt's syndrome, also referred to as uveoparotid fever, Heerfordt-Mylius syndrome, Heerfordt-Waldenström syndrome, and Waldenström’s uveoparotitis, is a rare manifestation of sarcoidosis...
  
  
• Hereditary progressive mucinous histiocytosis
  Hereditary progressive mucinous histiocytosis
  Hereditary progressive mucinous histiocytosis is an autosomal dominant or X-linked hereditary described on in women....
  
  
• Hypopigmented sarcoidosis
  Hypopigmented sarcoidosis
  Hypopigmented sarcoidosis is a cutaneous condition characterized by areas of hypopigmented skin. It is usually diagnosed in darkly pigmented races and may be the earliest sign of sarcoidosis....
  
  
• Ichthyosiform sarcoidosis
  Ichthyosiform sarcoidosis
  Ichthyosiform sarcoidosis is a cutaneous condition resembling ichthyosis vulgaris or acquired ichthyosis, with fine scaling usually on the distal extremities, by caused by sarcoidosis....
  
  
• Indeterminate cell histiocytosis
  Indeterminate cell histiocytosis
  Indeterminate cell histiocytosis is a cutaneous condition felt to be caused by dermal precursors of Langerhans cells....
  
  
• Interstitial granulomatous drug reaction
  Interstitial granulomatous drug reaction
  Interstitial granulomatous drug reaction is an uncommon, yet under-recognized, pattern of adverse reactions to medication....
  
  
• Langerhans cell histiocytosis
  Langerhans cell histiocytosis
  Langerhans cell Histiocytosis is a rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes...
  
   (Histiocytosis X)
• Letterer–Siwe disease
• Localized granuloma annulare
  Localized granuloma annulare
  Localized granuloma annulare is a skin condition of unknown cause, tending to affect children and young to middle-aged adults, usually appearing on the lateral or dorsal surfaces of the fingers or hands, elbows, dorsal feet, and ankles.- References :...
  
  
• Löfgren syndrome
  Löfgren syndrome
  Löfgren syndrome is a type of acute sarcoidosis that is frequent in Scandinavian, Irish, African and Puerto Rican women.It was characterized in 1953.Some have considered the condition to be imprecisely defined.-Presentation:...
  
  
• Lupus pernio
  Lupus pernio
  Lupus pernio is a chronic raised indurated lesion of the skin, often purplish in color. It resembles frostbite as it is seen on ears, cheeks, lips, nose, hands, fingers and forehead. It is pathognomonic of sarcoidosis. Microscopically, it resembles lupus vulgaris...
  
  
• Morpheaform sarcoidosis
  Morpheaform sarcoidosis
  Morpheaform sarcoidosis is a very rare cutaneous condition characterized by specific cutaneous skin lesions of sarcoidosis accompanied by substantial fibrosis, simulating morphea....
  
  
• Mucosal sarcoidosis
  Mucosal sarcoidosis
  Mucosal sarcoidosis is a cutaneous condition characterized by pinhead-sized papules that may be grouped and fused together to form a flat plaque....
  
  
• Multicentric reticulohistiocytosis
  Multicentric reticulohistiocytosis
  Multicentric reticulohistiocytosis is a multisystem disease beginning usually around the age of 50 years old, and is twice as common in women....
  
  
• Necrobiotic xanthogranuloma
  Necrobiotic xanthogranuloma
  Necrobiotic xanthogranuloma is a multisystem disease that affects older adults, and is characterized by prominent skin findings.- References :...
  
   (Necrobiotic xanthogranuloma with paraproteinemia)
• Non-X histiocytosis
  Non-X histiocytosis
  Non-X histiocytoses are a clinically well-defined group of cutaneous syndromes characterized by infiltrates of monocytes/macrophages, as opposed to X-type histiocytoses in which the infiltrates contain Langerhans cells...
  
  
• Papular sarcoid
  Papular sarcoid
  Papular sarcoid is a cutaneous condition characterized by papules, which are the most common morphology of cutaneous sarcoidosis....
  
  
• Papular xanthoma
  Papular xanthoma
  Papular xanthoma is a cutaneous condition that is a rare form of non-X histiocytosis....
  
  
• Patch-type granuloma annulare
  Patch-type granuloma annulare
  Patch-type granuloma annulare is a skin condition of unknown cause, more commonly affecting women between 30 and 70 years of age, characterized by flat or slightly palpable erythematous or red-brown skin lesions....
  
   (Macular granuloma annulare)
• Perforating granuloma annulare
  Perforating granuloma annulare
  Perforating granuloma annulare is a skin condition of unknown cause, usually appearing on the dorsal hands, presenting as papules with a central keratotic core.- References :...
  
   
• Progressive nodular histiocytosis
  Progressive nodular histiocytosis
  Progressive nodular histiocytosis is a cutaneous condition clinically characterized by the development of two types of skin lesions: superficial papules and deeper larger subcutaneous nodules....
  
  
• Reticulohistiocytoma
  Reticulohistiocytoma
  Reticulohistiocytoma is a cutaneous condition characterized by a solitary, firm, dermal skin lesion of less than 1cm in diameter. It usually occurs in young adults or middle aged people, most commonly in females. Affected regions include the head and neck region and the upper part of the trunk...
  
  
• Scar sarcoid
  Scar sarcoid
  Scar sarcoid is a cutaneous condition characterized by infiltration and elevation of tattoos and old flat scars due to sarcoidosis....
  
   (Sarcoidosis in scars)
• Sea-blue histiocytosis
  Sea-blue histiocytosis
  Sea-blue histiocytosis is a cutaneous condition that may occur as a familial inherited syndrome or as an acquired secondary or systemic infiltrative process.-Causes:It can be associated with the gene APOE.It can also be acquired...
  
  
• Subcutaneous granuloma annulare
  Subcutaneous granuloma annulare
  Subcutaneous granuloma annulare is a skin condition of unknown cause, most commonly affecting children, with boys affected twice as commonly as girls, characterized by skin lesions most often on the lower legs.- References :...
  
   (Deep granuloma annulare, Pseudorheumatoid nodule)
• Subcutaneous sarcoidosis
  Subcutaneous sarcoidosis
  Subcutaneous sarcoidosis is a cutaneous condition characterized by numerous 0.5- to 0.3-cm deep-seated nodules on the trunk and extremities....
  
   (Darier–Roussy disease, Darier–Roussy sarcoid)
• Systemic sarcoidosis
• Ulcerative sarcoidosis
  Ulcerative sarcoidosis
  Ulcerative sarcoidosis is a cutaneous condition affecting roughly 5% of people with sarcoidosis....
  
  
• Xanthoma disseminatum
  Xanthoma disseminatum
  Xanthoma disseminatum is a rare cutaneous condition that preferentially affects males in childhood, characterized by the insidious onset of small, yellow-red to brown papules and nodules that are discrete and disseminated.It is a histiocytosis syndrome.- References :...
  
   (Disseminated xanthosiderohistiocytosis, Montgomery syndrome)

Mucinoses

Mucinoses are a group of conditions caused by dermal

Dermis

The dermis is a layer of skin between the epidermis and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis...

 fibroblast

Fibroblast

A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen, the structural framework for animal tissues, and plays a critical role in wound healing...

s producing abnormally large amounts of mucopolysaccharides.

• Acral persistent papular mucinosis
  Acral persistent papular mucinosis
  Acral persistent papular mucinosis is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, characterized by bilaterally symmetrical, flesh-colored papules localized to the hands and wrists....
  
  
• Atypical lichen myxedematosus
  Atypical lichen myxedematosus
  Atypical lichen myxedematosus is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides....
  
   (Intermediate lichen myxedematosus)
• Atypical tuberous myxedema
  Atypical tuberous myxedema
  Atypical tuberous myxedema, also known as Jadassohn–Dosseker syndrome, is thought to represent a pure nodular variant of lichen myxedematosus....
  
   (Jadassohn–Dosseker syndrome)
• Cutaneous focal mucinosis
  Cutaneous focal mucinosis
  Cutaneous focal mucinosis is a skin condition characterized by a solitary nodule or papule....
  
  
• Cutaneous lupus mucinosis
  Cutaneous lupus mucinosis
  Cutaneous lupus mucinosis is a cutaneous condition characterized by lesions that present as asymptomatic skin-colored, at times reddish, 0.5–2 cm papules and nodules....
  
   (Papular and nodular mucinosis in lupus erythematosus, Papular and nodular mucinosis of Gold, Papulonodular mucinosis in lupus erythematosus)
• Discrete papular lichen myxedematosus
  Discrete papular lichen myxedematosus
  Discrete papular lichen myxedematosus is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides characterized by the occurrence of waxy, flesh-colored papules....
  
  
• Eccrine mucinosis
  Eccrine mucinosis
  Eccrine mucinosis is a cutaneous condition characterized by mucinosis, and described in HIV-infected patients....
  
  
• Follicular mucinosis (Alopecia mucinosa, Mucinosis follicularis, Pinkus’ follicular mucinosis, Pinkus’ follicular mucinosis–benign primary form)
• Localized lichen myxedematosus
  Localized lichen myxedematosus
  Localized lichen myxedematosus is a group of skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, a disease for which there is no treatment....
  
  
• Myxoid cyst
  Myxoid cyst
  A Myxoid cyst is a cutaneous condition often characterized by nail plate depression and grooves....
  
   (Digital mucous cyst, Mucous cyst)
• Myxoid lipoblastoma
  Myxoid lipoblastoma
  Myxoid lipoblastoma is a cutaneous condition characterized by excess mucin. It resembles myxoid liposarcoma....
  
  
• Neuropathia mucinosa cutanea
  Neuropathia mucinosa cutanea
  Neuropathia mucinosa cutanea is a cutaneous condition characterized by livedo reticularis on the legs and hyperesthesia....
  
  
• Nodular lichen myxedematosus
  Nodular lichen myxedematosus
  Nodular lichen myxedematosus is a cutaneous condition characterized by multiple nodules on the limbs and trunk, with a mild or absent papular component....
  
  
• Papular mucinosis
  Papular mucinosis
  Papular mucinosis is a rare skin disease. Localized and disseminated cases are called papular mucinosis or lichen myxedematosus while generalized, confluent papular forms with sclerosis are called scleromyxedema. Frequently, all three forms are regarded as papular mucinosis...
  
   (Generalized lichen myxedematosus, Sclerodermoid lichen myxedematosus, Scleromyxedema)
• Papular mucinosis of infancy
  Papular mucinosis of infancy
  Papular mucinosis of infancy is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, characterized by skin-colored or translucent papules....
  
   (Cutaneous mucinosis of infancy)
• Perifollicular mucinosis
  Perifollicular mucinosis
  Perifollicular mucinosis is a cutaneous condition characterized by mucinosis, and described in HIV-infected patients....
  
  
• Reticular erythematous mucinosis
  Reticular erythematous mucinosis
  Reticular erythematous mucinosis — also known as Midline mucinosis, Plaque-like cutaneous mucinosis, and REM syndrome — is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides. It is a disease that tends to affect women in the third and fourth decades of...
  
   (Midline mucinosis, Plaque-like cutaneous mucinosis, REM syndrome)
• Scleroderma
  Scleroderma
  Systemic sclerosis or systemic scleroderma is a systemic autoimmune disease or systemic connective tissue disease that is a subtype of scleroderma.-Skin symptoms:...
  
  
• Self-healing juvenile cutaneous mucinosis
  Self-healing juvenile cutaneous mucinosis
  Self-healing juvenile cutaneous mucinosis is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, and os characterized by the sudden onset of skin lesions and polyarthritis....
  
  
• Self-healing papular mucinosis
  Self-healing papular mucinosis
  Self-healing papular mucinosis is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides, and may present in adult and juvenile forms. The juvenile variant is also called self-healing juvenile cutaneous mucinosis....
  
  
• Stiff skin syndrome
  Stiff skin syndrome
  Stiff skin syndrome is a cutaneous condition characterized by ‘rock hard’ induration, thickening of the skin and subcutaneous tissues, limited joint mobility, and mild hypertrichosis in infancy or early childhood...
  
   (Congenital fascial dystrophy)

Neurocutaneous

Neurocutaneous conditions are due organic

Organ (anatomy)

In biology, an organ is a collection of tissues joined in structural unit to serve a common function. Usually there is a main tissue and sporadic tissues . The main tissue is the one that is unique for the specific organ. For example, main tissue in the heart is the myocardium, while sporadic are...

 nervous system

Nervous system

The nervous system is an organ system containing a network of specialized cells called neurons that coordinate the actions of an animal and transmit signals between different parts of its body. In most animals the nervous system consists of two parts, central and peripheral. The central nervous...

 disease or are psychiatric in etiology

Etiology

Etiology is the study of causation, or origination. The word is derived from the Greek , aitiologia, "giving a reason for" ....

.

• Atypical chronic pain syndrome
  Atypical chronic pain syndrome
  Atypical chronic pain syndrome is characterized by patients who will present to dermatologists with complaints of burning, pain, or dysesthesias in the skin or mucous membranes for which no identifiable pathology can be found....
  
  
• Body dysmorphic disorder
  Body dysmorphic disorder
  Body Dysmorphic Disorder is a type of mental illness, a somatoform disorder, wherein the affected person is exclusively concerned with body image, manifested as excessive concern about and preoccupation with a perceived defect of his or her physical features...
  
   (Dysmorphic syndrome, Dysmorphophobia)
• Brachioradial pruritus
  Brachioradial pruritus
  Brachioradial pruritus is becoming increasingly common, presenting in patients who are usually fair skinned, affluent, and middle aged that indulge in golf, tennis, sailing, or other leisure outdoor activities in sunny climates....
  
  
• Bromidrosiphobia
  Bromidrosiphobia
  Bromidrosiphobia is a neurosis in which a person is convinced that his/her sweat has a repugnant odor that keeps other people away. The patient is unable to accept any evidence to the contrary. Three-quarters of patients with bromidrosiphobia are male, with an average age of 25. Pimozide may be...
  
  
• Complex regional pain syndrome
  Complex regional pain syndrome
  Complex regional pain syndrome is a chronic progressive disease characterized by severe pain, swelling and changes in the skin. It often affects an arm or a leg and may spread to another part of the body.Though treatment is often unsatisfactory, early multimodal therapy can cause dramatic...
  
   (Reflex sympathetic dystrophy)
• Congenital insensitivity to pain with anhidrosis
  Congenital insensitivity to pain with anhidrosis
  Congenital insensitivity to pain with anhidrosis is an extremely rare inherited disorder of the nervous system which prevents the sensation of pain, heat, cold, or any real nerve-related sensations ; however, patients can still feel pressure. CIPA is the fourth type of hereditary sensory and...
  
  
• Delusional parasitosis
  Delusional parasitosis
  Delusional parasitosis is a form of psychosis whose victims acquire a strong delusional belief that they are infested with parasites, whereas in reality no such parasites are present...
  
   (Delusions of parasitosis, Ekbom syndrome, Monosymptomatic hypochondriacal psychosis)
• Dermatothlasia
  Dermatothlasia
  Dermatothlasia is a cutaneous neurosis characterized by a person's uncontrollable desire to rub or pinch him/herself to form bruised areas on the skin, sometimes as a defense against pain elsewhere....
  
  
• Factitious dermatitis
  Factitious dermatitis
  Factitious dermatitis is a form of factitious disorder in which patients will intentionally feign symptoms and produce signs of disease in an attempt to assume the patient role....
  
   (Dermatitis artefacta, Factitial dermatitis)
• Glossodynia
  Glossodynia
  Glossodynia or burning mouth syndrome is a condition characterized by a burning or tingling sensation on the lips, tongue, or entire mouth....
  
   (Burning mouth syndrome, Burning tongue, Orodynia)
• Levator ani syndrome
  Levator ani syndrome
  Levator ani syndrome is a condition characterized by brief intermittent burning pain or tenesmus of the rectal or perineal area....
  
  
• Malum perforans pedis
  Malum perforans pedis
  Malum perforans pedis is a cutaneous condition of chronic, trophic, ulcerative disease seen on the sole in denervating diseases, particularly tabes dorsalis....
  
   (Neurotrophic ulcer, Perforating ulcer of the foot)
• Meralgia paresthetica (Roth–Bernhardt disease)
• Neurotic excoriations
  Neurotic excoriations
  Neurotic excoriations is a condition in which patients produce skin lesions through repetitive, compulsive excoriation of their skin....
  
  
• Notalgia paresthetica
  Notalgia paresthetica
  Notalgia paresthetica is a chronic sensory neuropathy...
  
   (Hereditary localized pruritus, Posterior pigmented pruritic patch, Subscapular pruritus)
• Postencephalitic trophic ulcer
  Postencephalitic trophic ulcer
  Postencephalitic trophic ulcer is an ulceration of the nose similar to trigeminal trophic lesions, and has been reported following epidemic encephalitis and herpes zoster of the trigeminal nerve....
  
  
• Psychogenic pruritus
  Psychogenic pruritus
  Psychogenic pruritus is a common manifestation of chronic anxiety, usually a localized itch, especially in the anogenital area....
  
  
• Riley–Day syndrome (Familial dysautonomia)
• Scalp dysesthesia
  Scalp dysesthesia
  Scalp dysesthesia is a cutaneous condition characterised by pain and burning sensations without objective physical examination findings.Use of antidepressants in treatment has been described....
  
  
• Sciatic nerve injury
  Sciatic nerve injury
  Sciatic nerve injury may occur from improperly performed injections into the buttock, and may result in sensory loss....
  
  
• Scrotodynia
• Syringomyelia
  Syringomyelia
  Syringomyelia is a generic term referring to a disorder in which a cyst or cavity forms within the spinal cord. This cyst, called a syrinx, can expand and elongate over time, destroying the spinal cord. The damage may result in pain, paralysis, weakness, and stiffness in the back, shoulders, and...
  
   (Morvan's disease)
• Traumatic neuroma
  Traumatic neuroma
  A traumatic neuroma is a type of neuroma which results from trauma to a nerve, usually during a surgical procedure. The most common oral locations are on the tongue and near the mental foramen of the mouth. They are relatively rare on the head and neck.It is also known as "pseudoneuroma"....
  
   (Amputation neuroma)
• Trichotillomania
  Trichotillomania
  Trichotillomania, which is classified as an impulse control disorder by DSM-IV, is the compulsive urge to pull out one's own hair leading to noticeable hair loss, distress, and social or functional impairment. It is often chronic and difficult to treat....
  
   (Trichotillosis)
• Trigeminal neuralgia
  Trigeminal neuralgia
  Trigeminal neuralgia , tic douloureux is a neuropathic disorder characterized by episodes of intense pain in the face, originating from the trigeminal nerve. It has been described as among the most painful conditions known...
  
   (Tic douloureux)
• Trigeminal trophic lesion
  Trigeminal trophic lesion
  Trigeminal trophic lesions are a cutaneous condition caused by the interruption of peripheral or central sensory pathways of the trigeminal nerve that result in a slowly enlarging, uninflammed ulcer on the cheek beside the ala nasi.Sixty cases were reported from 1982 to 2002.- See also :*...
  
   (Trigeminal trophic syndrome)
• Vulvodynia
  Vulvodynia
  Vulvodynia is a chronic pain syndrome that affects the vulvar area and occurs without an identifiable cause or visible pathology categorized in the ICD-9 group 625—specifically ICD-9 625.7, which is for pain and other disorders of the female genital organs...
  
   (Vestibulodynia)

Noninfectious immunodeficiency-related

Noninfectious immunodeficiency-related cutaneous conditions are caused by T-cell and/or B-cell dysfunction.

• Bare lymphocyte syndrome
  Bare lymphocyte syndrome
  Bare lymphocyte syndrome is a condition caused by mutations in certain genes of the major histocompatibility complex. It is a form of severe combined immunodeficiency.-Presentation:...
  
  
• Chronic granulomatous disease
  Chronic granulomatous disease
  Chronic granulomatous disease is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds used to kill certain ingested pathogens...
  
   (Bridges–Good syndrome, Chronic granulomatous disorder, Quie syndrome)
• Common variable immunodeficiency
  Common variable immunodeficiency
  Common variable immunodeficiency is a group of approximately 150 primary immunodeficiencies , which have a common set of symptoms but which have different underlying causes.Common variable immunodeficiency is the most commonly encountered primary immunodeficiency.-Causes and types:CVID...
  
   (Acquired hypogammaglobulinemia)
• Complement deficiency
  Complement deficiency
  Complement deficiency is an immunodeficiency of absent or suboptimal functioning of one of the complement system proteins.The disorders can be divided into two categories:...
  
  
• DiGeorge syndrome
  DiGeorge syndrome
  22q11.2 deletion syndrome, which has several presentations including DiGeorge syndrome , DiGeorge anomaly, velo-cardio-facial syndrome, Shprintzen syndrome, conotruncal anomaly face syndrome, Strong syndrome, congenital thymic aplasia, and thymic hypoplasia is a syndrome caused by the deletion of a...
  
   (DiGeorge anomaly, Thymic hypoplasia)
• Graft-versus-host disease
  Graft-versus-host disease
  Graft-versus-host disease is a common complication after a stem cell transplant or bone marrow transplant from another person . Immune cells in the donated marrow or stem cells recognize the recipient as "foreign". The transplanted immune cells then attack the host's body cells...
  
  
• Griscelli syndrome
  Griscelli syndrome
  Griscelli syndrome is a rare autosomal recessive disorder characterized by albinism with immunodeficiency, that usually causes death by early childhood.-Types:...
  
  
• Hyper-IgE syndrome
  Hyper-IgE syndrome
  Hyperimmunoglobulin E syndrome , also called Job's syndrome and Buckley syndrome, is a heterogeneous group of immune disorders.-Presentation:...
  
   (Buckley syndrome, Job syndrome)
• Immunodeficiency with hyper-IgM
• Immunodeficiency–centromeric instability–facial anomalies syndrome (ICF syndrome)
• Isolated IgA deficiency
• Isolated primary IgM deficiency
• Janus kinase 3 deficiency
  Janus kinase 3 deficiency
  Janus kinase 3 deficiency or JAK3 deficiency is a defect in the body's cytokine receptors and their signaling. JAK3 encodes Janus kinase 3, a tyrosine kinase that belongs to the Janus family. JAK3 functions in signal transduction and interacts with members of the STAT family. The cause of JAK3...
  
  
• Leukocyte adhesion molecule deficiency
  Leukocyte adhesion molecule deficiency
  Leukocyte adhesion molecule deficiency is a rare autosomal recessive disorder characterized by recurrent bacterial and fungal infections and impaired neutrophil migration....
  
  
• LIG4 syndrome
  LIG4 syndrome
  LIG4 syndrome is a rare condition characterized by, among other findings, photosensitivity and telangiectasias....
  
  
• Myeloperoxidase deficiency
  Myeloperoxidase deficiency
  Myeloperoxidase deficiency is a common genetic disorder featuring deficiency, either in quantity or function, of myeloperoxidase, an enzyme found in certain phagocytic immune cells, especially polymorphonuclear leukocytes....
  
  
• Neutrophil immunodeficiency syndrome
  Neutrophil immunodeficiency syndrome
  Neutrophil immunodeficiency syndrome is a condition caused by mutations in the Rac2 gene.- See also :* Immunodeficiency with hyper-IgM* List of cutaneous conditions* Chronic granulomatous disease- References :...
  
  
• Nezelof syndrome
  Nezelof syndrome
  Nezelof syndrome is an autosomal recessive congenital immunodeficiency condition due to underdevelopment of the thymus.An association with CD44 has been proposed.-History:...
  
   (Thymic dysplasia with normal immunoglobulins)
• Omenn syndrome
  Omenn syndrome
  Omenn syndrome is an autosomal recessive severe combined immunodeficiency associated with mutations in the recombination activating genes , affecting circulating levels of both B-cells and T-cells.-Symptoms:...
  
  
• Purine nucleoside phosphorylase deficiency
  Purine nucleoside phosphorylase deficiency
  Purine nucleoside phosphorylase deficiency, often called PNP-deficiency, is a rare autosomal recessive metabolic disorder which results in severe combined immunodeficiency.-Signs and symptoms:...
  
  
• Severe combined immunodeficiency
  Severe combined immunodeficiency
  Severe combined immunodeficiency , is a genetic disorder in which both "arms" of the adaptive immune system are impaired due to a defect in one of several possible genes. SCID is a severe form of heritable immunodeficiency...
  
   (Alymphocytosis, Glanzmann–Riniker syndrome, Severe mixed immunodeficiency syndrome, Thymic alymphoplasia)
• Shwachman–Bodian–Diamond syndrome
  Shwachman–Bodian–Diamond syndrome
  Shwachman–Diamond syndrome is a rare congenital disorder characterized by exocrine pancreatic insufficiency, bone marrow dysfunction, skeletal abnormalities, and short stature. After cystic fibrosis , it is the second most common cause of exocrine pancreatic insufficiency in children.-Clinical...
  
  
• Thymoma with immunodeficiency
  Thymoma with immunodeficiency
  Thymoma with immunodeficiency is a condition that occurs in adults in whom hypogammaglobulinemia, deficient cell-mediated immunity, and benign thymoma may develop almost simultaneously....
  
   (Good syndrome)
• Transient hypogammaglobulinemia of infancy
  Transient hypogammaglobulinemia of infancy
  Transient hypogammaglobulinemia of infancy is a form of hypogammaglobulinemia appearing after birth, leading to a reduction in the level of IgG, and also sometimes IgA and IgM...
  
  
• Warts–hypogammaglobulinemia–infections–myelokathexis syndrome (WHIM syndrome)
• Wiskott–Aldrich syndrome
• X-linked agammaglobulinemia
  X-linked agammaglobulinemia
  X-linked agammaglobulinemia is a rare X-linked genetic disorder that was discovered in 1952 which affects the body's ability to fight infection. XLA is an X-linked disorder, and therefore is more common in males...
  
   (Bruton syndrome, Sex-linked agammaglobulinemia)
• X-linked hyper-IgM syndrome
• X-linked hypogammaglobulinemia
• X-linked lymphoproliferative disease
  X-linked lymphoproliferative disease
  X-linked lymphoproliferative disease is a lymphoproliferative disorder.-XLP1:There is a mutation on the X-chromosome that has been found to be associated with a T- and NK-cell lymphoproliferative disorder. The mutation is on the long arm of the chromosome, at position 25, which is denoted as Xq25...
  
   (Duncan's disease)
• X-linked neutropenia

Nutrition-related

Nutrition-related cutaneous conditions are caused by malnutrition

Malnutrition

Malnutrition is the condition that results from taking an unbalanced diet in which certain nutrients are lacking, in excess , or in the wrong proportions....

 due to an improper or inadequate diet

Diet (nutrition)

In nutrition, diet is the sum of food consumed by a person or other organism. Dietary habits are the habitual decisions an individual or culture makes when choosing what foods to eat. With the word diet, it is often implied the use of specific intake of nutrition for health or weight-management...

.

• Biotin deficiency
  Biotin deficiency
  Biotin deficiency is a rare nutritional disorder which can become serious, even fatal, if allowed to progress untreated. It can occur in people of any age, ancestry, or gender...
  
  
• Carotenemia
• Essential fatty acid deficiency
• Folic acid deficiency
• Hypervitaminosis A
  Hypervitaminosis A
  Hypervitaminosis A refers to the effects of excessive vitamin A intake.-Presentation:Effects include* Birth defects* Liver problems* Reduced bone mineral density that may result in osteoporosis* Coarse bone growths...
  
  
• Hypovitaminosis A
  Hypovitaminosis A
  Hypovitaminosis A is common in children in the developing world, most often associated with diseases of fat malabsorption....
  
   (Phrynoderma)
• Iron deficiency
  Iron deficiency (medicine)
  Iron deficiency is one of the most common of the nutritional deficiencies. Iron is present in all cells in the human body, and has several vital functions...
  
   
  
• Kwashiorkor
  Kwashiorkor
  Kwashiorkor is an acute form of childhood protein-energy malnutrition characterized by edema, irritability, anorexia, ulcerating dermatoses, and an enlarged liver with fatty infiltrates. The presence of edema caused by poor nutrition defines kwashiorkor...
  
  
• Lycopenemia
  Lycopenemia
  Lycopenemia is a skin condition caused by excessive ingestion of red foods, such as tomatoes, beets, chili beans, and various fruits and berries, which leads to a reddish discoloration of the skin....
  
  
• Maple syrup urine disease
  Maple syrup urine disease
  Maple syrup urine disease , also called branched-chain ketoaciduria, is an autosomal recessive metabolic disorder affecting branched-chain amino acids. It is one type of organic acidemia...
  
  
• Marasmus
  Marasmus
  Marasmus is a form of severe protein-energy malnutrition characterized by energy deficiency.A child with marasmus looks emaciated. Body weight may be reduced to less than 80% of the average weight that corresponds to the height . Marasmus occurrence increases prior to age 1, whereas kwashiorkor...
  
  
• Niacin deficiency (Pellagra, Vitamin B₃ deficiency)
• Selenium deficiency
  Selenium deficiency
  Selenium deficiency is relatively rare in healthy well-nourished individuals. Few cases have been reported.-Causes:It can occur in patients with severely compromised intestinal function, those undergoing total parenteral nutrition, those who have had gastrointestinal bypass surgery, and also on...
  
  
• Vitamin B₁ deficiency (Beriberi, Thiamine deficiency)
• Vitamin B₁₂ deficiency
  Vitamin B12 deficiency
  Vitamin B12 deficiency or hypocobalaminemia is a low blood level of vitamin B12, it can cause permanent damage to nervous tissue as a long term effect. Vitamin B12 was discovered from its relationship to the disease pernicious anemia, which is an autoimmune disease that destroys parietal cells in...
  
   (Cyanocobalamin deficiency)
• Vitamin B₂ deficiency (Ariboflavinosis, Riboflavin deficiency)
• Vitamin B₆ deficiency (Pyridoxine deficiency)
• Vitamin B₆ excess
  Vitamin B6 excess
  Vitamin B6 excess may present with a subepidermal vesicular dermatosis and sensory peripheral neuropathy....
  
   (Pyridoxine excess)
• Vitamin C deficiency (Scurvy)
• Vitamin K deficiency
  Vitamin K deficiency
  Vitamin K deficiency is a form of avitaminosis resulting from insufficient vitamin K.-Causes:Vitamin K-deficiency may occur by disturbed intestinal uptake , by therapeutic or accidental intake of vitamin K-antagonists or, very rarely, by nutritional vitamin K deficiency...
  
  
• Zinc deficiency
  Zinc deficiency
  Zinc deficiency is insufficient zinc to meet the needs of biological organisms. It can occur in both plants and animals. Zinc deficient soil is soil in which there is insufficient zinc to allow plants to grow normally.-Description:...
  
  

Papulosquamous hyperkeratotic

Papulosquamous hyperkeratotic

Hyperkeratosis

Hyperkeratosis is thickening of the stratum corneum, often associated with a qualitative abnormality of the keratin, and also usually accompanied by an increase also in the granular layer...

 cutaneous conditions are those that present with papule

Papule

A papule is a circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to 1 cm.With regard to the quote "...varying in size from a pinhead to 1cm," depending on which text is referenced, some authors state the cutoff between a papule and a plaque as 0.5cm,...

s and scales caused by a thickening of the stratum corneum

Stratum corneum

The stratum corneum is the outermost layer of the epidermis, consisting of dead cells that lack nuclei and organelles. The purpose of the stratum corneum is to form a barrier to protect underlying tissue from infection, dehydration, chemicals and mechanical stress...

.

• Confluent and reticulated papillomatosis (Confluent and reticulated papillomatosis of Gougerot and Carteaud, Familial cutaneous papillomatosis, Familial occurrence of confluent and reticulated papillomatosis)
• Digitate dermatosis
  Digitate dermatosis
  Digitate dermatosis is a distinct variant of small-plaque parapsoriasis with lesions in the shape of a finger and distributed symmetrically on the flanks....
  
  
• Drug-induced keratoderma
  Drug-induced keratoderma
  Drug-induced keratoderma is a cutaneous condition characterized by a a hornlike skin texture....
  
  
• Exfoliative dermatitis (Dermatitis exfoliativa, Erythroderma, Red man syndrome)
• Florid cutaneous papillomatosis
  Florid cutaneous papillomatosis
  Florid cutaneous papillomatosis is the sudden onset of numerous cutaneous papillomas that are indistinguishable from viral warts, and associated with underlying malignancy.- History :...
  
  
• Granular parakeratosis
  Granular parakeratosis
  Granular parakeratosis is a cutaneous condition characterized by brownish-red keratotic papules that can coalesce into plaques....
  
   (Axillary granular parakeratosis, Intertriginous granular parakeratosis)
• Keratolysis exfoliativa
  Keratolysis exfoliativa
  Keratolysis exfoliativa, is a harmless condition of the skin. Although this particular condition is asymptomatic, it is often misdiagnosed as chronic contact dermatitis or psoriasis. It is primarily located on the palms of the hands and soles of the feet...
  
   (Lamellar dyshidrosis, Recurrent focal palmar peeling, Recurrent palmar peeling)
• Keratosis punctata of the palmar creases
  Keratosis punctata of the palmar creases
  Keratosis punctata of the palmar creases is a common skin disorder that occurs most often in black patients, with skin lesions that are 1 to...
  
   (Hyperkeratosis penetrans, Hyperkeratosis punctata, Keratodermia punctata, Keratosis punctata, Keratotic pits of the palmar creases, Lenticular atrophia of the palmar creases, Punctate keratosis of the palmar creases)
• Meesmann corneal dystrophy
• Paraneoplastic keratoderma
  Paraneoplastic keratoderma
  Paraneoplastic keratoderma is a cutaneous condition characterized by a a hornlike skin texture associated with an internal malignancy....
  
  
• Pityriasis rosea
  Pityriasis rosea
  Pityriasis rosea is a skin rash. It is non-dangerous but may inflict substantial discomfort on some people...
  
   (Pityriasis rosea Gibert)
• Pityriasis rubra pilaris
  Pityriasis rubra pilaris
  Pityriasis rubra pilaris refers to a group of chronic disorders characterized by reddish orange, scaling plaques and keratotic follicular papules...
  
   (Devergie's disease, Lichen ruber acuminatus, Lichen ruber pilaris)
• Pure hair-nail type ectodermal dysplasia
  Pure hair-nail type ectodermal dysplasia
  Pure hair-nail type ectodermal dysplasia is a genetic mutation in the "hair matrix and cuticle keratin KRTHB5 gene" that causes ectodermal dysplasia of hair and nail type. Manifestations of this disorder include onychodystrophy and severe hypotrichosis. It represents as an autosomal dominant trait....
  
  
• Small plaque parapsoriasis (Chronic superficial dermatitis)
• Tripe palms
  Tripe palms
  Tripe palms are a cutaneous condition characterized by ridged velvety lesions on the palms.It is a paraneoplastic syndrome....
  
  
• Xanthoerythrodermia perstans
  Xanthoerythrodermia perstans
  Xanthoerythrodermia perstans is a distinct variant of small-plaque parapsoriasis with lesions that are yellow in color....
  
  

Palmoplantar keratodermas

Palmoplantar keratodermas are a diverse group of hereditary and acquired keratodermas in which there is hyperkeratosis

Hyperkeratosis

Hyperkeratosis is thickening of the stratum corneum, often associated with a qualitative abnormality of the keratin, and also usually accompanied by an increase also in the granular layer...

 of the skin of the palms and soles.

• Acrokeratoelastoidosis of Costa
  Acrokeratoelastoidosis of Costa
  Acrokeratoelastoidosis of Costa is a familial condition characterized by multiple keratotic papules on the dorsum of the hands and feet, palms, soles, in which electron microscopy shows rarified, abnormal elastic tissue.It was characterized in 1953.Treatments such as liquid nitrogen, salicylic...
  
   (Keratoelastoidosis marginalis)
• Aquagenic keratoderma (Acquired aquagenic palmoplantar keratoderma, Aquagenic syringeal acrokeratoderma, Aquagenic wrinkling of the palms, Transient reactive papulotranslucent acrokeratoderma)
• Bart–Pumphrey syndrome
  Bart–Pumphrey syndrome
  Bart–Pumphrey syndrome is a cutaneous condition characterized by hyperkeratoses over the metacarpophalangeal and proximal and distal interphalangeal joints....
  
   (Palmoplantar keratoderma with knuckle pads and leukonychia and deafness)
• Camisa disease
  Camisa disease
  Camisa disease is the variant form of Vohwinkel syndrome, characterized by ichthyosis and normal hearing.It is associated with loricrin.It was characterized in 1984 and 1988....
  
  
• Carvajal syndrome
  Carvajal syndrome
  Carvajal syndrome is a cutaneous condition, a form of ichthyosis, inherited in an autosomal recessive fashion, and due to a defect in desmoplakin...
  
   (Striate palmoplantar keratoderma with woolly hair and cardiomyopathy, Striate palmoplantar keratoderma with woolly hair and left ventricular dilated cardiomyopathy)
• Corneodermatoosseous syndrome (CDO syndrome)
• Diffuse epidermolytic palmoplantar keratoderma
  Diffuse epidermolytic palmoplantar keratoderma
  Diffuse epidermolytic palmoplantar keratoderma is one of the most common patterns of palmoplantar keratoderma, an autosomal dominant condition that presents within the first few months of life, characterized by a well-demarcated,...
  
   (Palmoplantar keratoderma cum degeneratione granulosa Vörner, Vörner's epidermolytic palmoplantar keratoderma, Vörner keratoderma)
• Diffuse nonepidermolytic palmoplantar keratoderma
  Diffuse nonepidermolytic palmoplantar keratoderma
  Diffuse nonepidermolytic palmoplantar keratoderma is inherited as an autosomal dominant condition and is present from infancy, characterized by...
  
   (Diffuse orthohyperkeratotic keratoderma, Hereditary palmoplantar keratoderma, Keratosis extremitatum progrediens, Keratosis palmoplantaris diffusa circumscripta, Tylosis, Unna–Thost disease, Unna–Thost keratoderma)
• Erythrokeratodermia variabilis
  Erythrokeratodermia variabilis
  Erythrokeratodermia variabilis is a rare autosomal dominant disorder that usually presents at birth or during the...
  
   (Erythrokeratodermia figurata variabilis, Keratosis extremitatum progrediens, Keratosis palmoplantaris transgrediens et progrediens, Mendes da Costa syndrome, Mendes da Costa type erythrokeratodermia, Progressive symmetric erythrokeratoderma)
• Focal acral hyperkeratosis
  Focal acral hyperkeratosis
  Focal acral hyperkeratosis is a late-onset keratoderma, inherited as an autosomal dominant condition, characterized by oval or polygonal crateriform papules developing along the border of the hands, feet, and wrists.It is considered similar to Costa acrokeratoelastoidosis.-See...
  
   (Acrokeratoelastoidosis lichenoides, Degenerative collagenous plaques of the hand)
• Focal palmoplantar and gingival keratosis
  Focal palmoplantar and gingival keratosis
  Focal palmoplantar and gingival keratosis is a rare autosomal dominant disease whose clinical features, and in particular, pathologic alterations and molecular etiology remain to be well defined....
  
  
• Focal palmoplantar keratoderma with oral mucosal hyperkeratosis
  Focal palmoplantar keratoderma with oral mucosal hyperkeratosis
  Focal palmoplantar keratoderma with oral mucosal hyperkeratosis is an autosomal dominant keratoderma that represents a clinical...
  
   (Focal epidermolytic palmoplantar keratoderma, Hereditary painful callosities, Hereditary painful callosity syndrome, Keratosis follicularis, Keratosis palmoplantaris nummularis, Nummular epidermolytic palmoplantar keratoderma)
• Haim–Munk syndrome
  Haim–Munk syndrome
  Haim–Munk syndrome is a cutaneous condition caused by a mutation in the Cathepsin C gene....
  
   (Palmoplantar keratoderma with periodontitis and arachnodactyly and acro-osteolysis)
• Hidrotic ectodermal dysplasia (Alopecia congenita with keratosis palmoplantaris, Clouston syndrome, Clouston's hidrotic ectodermal dysplasia, Fischer–Jacobsen–Clouston syndrome, Keratosis palmaris with drumstick fingers, Palmoplantar keratoderma and clubbing)
• Howel–Evans syndrome
  Howel–Evans syndrome
  Howel–Evans syndrome is an extremely rare condition in which the skin of the...
  
   (Familial keratoderma with carcinoma of the esophagus, Focal non-epidermolytic palmoplantar keratoderma with carcinoma of the esophagus, Palmoplantar ectodermal dysplasia type III, Palmoplantar keratoderma associated with esophageal cancer, Tylosis, Tylosis–esophageal carcinoma)
• Hystrix-like ichthyosis–deafness syndrome
  Hystrix-like ichthyosis–deafness syndrome
  Hystrix-like ichthyosis–deafness syndrome is a cutaneous condition characterized by a keratoderma....
  
   (HID syndrome)
• Keratoderma climactericum
  Keratoderma climactericum
  Keratoderma climactericum, also known as "Climacteric keratoderma," "Haxthausen's disease," and "Acquired plantar keratoderma," is a skin condition characterized by hyperkeratosis of the palms and soles beginning at about the time of menopause....
  
   (Acquired plantar keratoderma, Climacteric keratoderma, Haxthausen's disease)
• Keratosis punctata palmaris et plantaris
  Keratosis punctata palmaris et plantaris
  Keratosis punctata palmaris et plantaris Keratosis punctata palmaris et plantaris Keratosis punctata palmaris et plantaris (also known as "Autosomal-dominant hereditary punctate keratoderma associated with malignancy," "Buschke–Fischer–Brauer disease," "Davis Colley disease," "Keratoderma...
  
   (Buschke–Fischer–Brauer disease, Davis Colley disease, Keratoderma disseminatum palmaris et plantaris, Keratosis papulosa, Keratoderma punctatum, Keratodermia punctata, Keratoma hereditarium dissipatum palmare et plantare, Palmar and plantar seed dermatoses, Palmar keratoses, Papulotranslucent acrokeratoderma, Punctate keratoderma, Punctate keratoses of the palms and soles, Maculosa disseminata)
• Keratitis–ichthyosis–deafness syndrome (Erythrokeratodermia progressiva Burns, Ichthyosiform erythroderma with corneal involvement and deafness, KID syndrome)
• Mal de Meleda (Acral keratoderma, Gamborg–Nielsen keratoderma, Mutilating palmoplantar keratoderma of the Gamborg–Nielsen type, Palmoplantar ectodermal dysplasia type VIII, Palmoplantar keratoderma of the Norrbotten type)
• Naxos syndrome
  Naxos syndrome
  Naxos syndrome is a cutaneous condition characterized by a palmoplantar keratoderma...
  
   (Diffuse non-epidermolytic palmoplantar keratoderma with woolly hair and cardiomyopathy, Diffuse palmoplantar keratoderma with woolly hair and arrythmogenic right ventricular cardiomyopathy of Naxos, Naxos disease)
• Olmsted syndrome
  Olmsted syndrome
  Olmsted syndrome is a keratoderma of the palms and soles, with flexion deformity of the digits, that begins in infancy.Treatment with retinoids has been described.- See also :* Palmoplantar...
  
   (Mutilating palmoplantar keratoderma with periorificial keratotic plaques, Mutilating palmoplantar keratoderma with periorificial plaques, Polykeratosis of Touraine)
• Pachyonychia congenita type I
  Pachyonychia congenita type I
  Pachyonychia congenita type I is an autosomal dominant keratoderma that principally involves the plantar surfaces, but also with nails changes that may be evident at birth but more commonly develop within the first few months of life.- See also :* Palmoplantar keratoderma* List of cutaneous...
  
   (Jadassohn–Lewandowsky syndrome)
• Pachyonychia congenita type II
  Pachyonychia congenita type II
  Pachyonychia congenita type II is an autosomal dominant keratoderma presenting with a limited focal plantar keratoderma that may be very minor, with nails changes that may be evident at birth, but more commonly develop within the first few months of life....
  
   (Jackson–Lawler pachyonychia congenita, Jackson–Sertoli syndrome)
• Palmoplantar keratoderma and spastic paraplegia
  Palmoplantar keratoderma and spastic paraplegia
  Palmoplantar keratoderma and spastic paraplegia is an autosomal dominant or x-linked dominant condition that begins in early childhood with thick focal keratoderma over the soles and, to a lesser extent, the palms....
  
   (Charcot–Marie–Tooth disease with palmoplantar keratoderma and nail dystrophy)
• Palmoplantar keratoderma of Sybert
  Palmoplantar keratoderma of Sybert
  Palmoplantar keratoderma of Sybert is an extremely rare autosomal dominant keratoderma Palmoplantar keratoderma of Sybert (also known as "Greither palmoplantar keratoderma," "Greither syndrome," "Keratosis extremitatum hereditaria progrediens," "Keratosis palmoplantaris transgrediens et...
  
   (Greither palmoplantar keratoderma, Greither syndrome, Keratosis extremitatum hereditaria progrediens, Keratosis palmoplantaris transgrediens et progrediens, Sybert keratoderma, Transgrediens and progrediens palmoplantar keratoderma)
• Papillon–Lefèvre syndrome (Palmoplantar keratoderma with periodontitis)
• Porokeratosis plantaris discreta
  Porokeratosis plantaris discreta
  Porokeratosis plantaris discreta is a skin condition that occurs in adults, with a 4:1 female preponderance, characterized by a sharply marginated, rubbery, wide-based papule.It is also known as "Steinberg's lesion".It was characterized in 1970....
  
  
• Punctate palmoplantar keratoderma
  Punctate palmoplantar keratoderma
  Punctate palmoplantar keratoderma is a form of palmoplantar keratoderma in which many tiny "raindrop" keratoses involve the palmoplantar surface, skin lesions which may involve the whole of the palmoplantar surface, or may be more restricted in their distribution.* Type 1: Keratosis punctata...
  
  
• Schöpf–Schulz–Passarge syndrome (Eyelid cysts with palmoplantar keratoderma and hypodontia and hypotrichosis)
• Scleroatrophic syndrome of Huriez
  Scleroatrophic syndrome of Huriez
  Scleroatrophic syndrome of Huriez is an autosomal dominant keratoderma with sclerodactyly present at birth with a diffuse symmetric keratoderma of the palms and soles.An association...
  
   (Huriez syndrome, Palmoplantar keratoderma with scleroatrophy, Palmoplantar keratoderma with sclerodactyly, Scleroatrophic and keratotic dermatosis of the limbs, Sclerotylosis)
• Striate palmoplantar keratoderma
  Striate palmoplantar keratoderma
  Striate palmoplantar keratoderma is a cutaneous condition, an autosomal...
  
   (Acral keratoderma, Brünauer–Fuhs–Siemens type of palmoplantar keratoderma, Focal non-epidermolytic palmoplantar keratoderma, Keratosis palmoplantaris varians, Palmoplantar keratoderma areata, Palmoplantar keratoderma striata, Wachter keratoderma, Wachters palmoplantar keratoderma)
• Spiny keratoderma
  Spiny keratoderma
  Spiny keratoderma is an autosomal dominant keratoderma of late onset that develops in patients aged 12 to 50, characterized by multiple tiny keratotic plugs, mimicking the spines on a music box, involving the entire palmoplantar surfaces....
  
   (Porokeratosis punctata palmaris et plantaris, Punctate keratoderma, Punctate porokeratosis of the palms and soles)
• Tyrosinemia type II
  Tyrosinemia type II
  Tyrosinemia type II is an autosomal recessive condition with onset between ages 2 and 4 years, when painful circumscribed calluses develop on the pressure points of the palm of the hand and sole of the foot.-Pathophysiology:Type II tyrosinemia is caused by a deficiency of the enzyme tyrosine...
  
   (Oculocutaneous tyrosinemia, Richner–Hanhart syndrome)
• Vohwinkel syndrome
  Vohwinkel syndrome
  Vohwinkel syndome is a diffuse autosomal dominant keratoderma with onset in early infancy characterized by a honeycombed keratoderma involving the palmoplantar surfaces...
  
   (Keratoderma hereditaria mutilans, Keratoma hereditaria mutilans, Mutilating keratoderma of Vohwinkel, Mutilating palmoplantar keratoderma)

Pregnancy-related

Pregnancy-related cutaneous conditions are a group of skin changes observed during pregnancy

Pregnancy

Pregnancy refers to the fertilization and development of one or more offspring, known as a fetus or embryo, in a woman's uterus. In a pregnancy, there can be multiple gestations, as in the case of twins or triplets...

.

• Impetigo herpetiformis
  Impetigo herpetiformis
  Impetigo herpetiformis is a form of severe pustular psoriasis occurring in pregnancy which may occur during any trimester.It is the only well known pustular psoriasis which is treated with steroids.- References :...
  
  
• Intrahepatic cholestasis of pregnancy
  Intrahepatic Cholestasis of Pregnancy
  Intrahepatic cholestasis of pregnancy in the United Kingdom, is a medical condition in which cholestasis occurs during pregnancy...
  
   (Cholestasis of pregnancy, Jaundice of pregnancy, Obstetric cholestasis, Prurigo gravidarum)
• Linea nigra
• Pemphigoid gestationis (Gestational pemphigoid, Herpes gestationis)
• Prurigo gestationis
  Prurigo gestationis
  Prurigo gestationis is an eruption consisting of pruritic, excoriated papules of the proximal limbs and upper trunk, most often occurring between the 20th and 34th week of...
  
   (Besnier prurigo, Early-onset prurigo of pregnancy, Linear IgM dermatosis of pregnancy, Papular dermatitis of pregnancy, Prurigo of pregnancy, Spangler's papular dermatitis of pregnancy)
• Pruritic folliculitis of pregnancy
  Pruritic folliculitis of pregnancy
  Pruritic folliculitis of pregnancy is a dermatosis of pregnancy characterized by small follicular pustules scattered widely over the trunk, appearing during the second or third trimester, and resolving by 2 or 3 weeks after delivery....
  
  
• Pruritic urticarial papules and plaques of pregnancy (Late-onset prurigo of pregnancy, Polymorphic eruption of pregnancy, PUPPP syndrome, Toxemic rash of pregnancy, Toxic erythema of pregnancy)
• Striae gravidarum
  Striae gravidarum
  Often referred to as pregnancy stretch marks, striae gravidarum is a form of scarring of the skin of the abdominal due to sudden weight gain during pregnancy. These off-color blemishes are caused by the tearing of the dermis, resulting in atrophy and loss of rete ridges. These scars often appear as...
  
  

Pruritic

Pruritus, commonly known as itchiness, is a sensation exclusive to the skin, and characteristic of many skin conditions.

• Adult blaschkitis
  Adult blaschkitis
  Adult blaschkitis is a rare inflammatory skin condition presenting as pruritic papules and vesicles along multiple lines of Blaschko....
  
  
• Aquadynia
  Aquadynia
  Aquadynia is a variant of aquagenic pruritus, and characterized by a widespread burning pain that lasts 15 to 45 minutes after water exposure....
  
  
• Aquagenic pruritus
  Aquagenic pruritus
  Aquagenic pruritus is a skin disease characterized by the development of severe, intense, prickling-like epidermal itching that is without observable skin lesions and that is evoked by contact with water.-Presentation:...
  
  
• Biliary pruritus
  Biliary pruritus
  Biliary pruritus is caused by chronic liver disease with obstructive jaundice, characterized by a severe generalized itchy sensation....
  
  
• Cholestatic pruritus
  Cholestatic pruritus
  Cholestatic pruritus is the sensation of itch due to nearly any liver disease, but the most commonly associated entities are primary biliary cirrhosis, primary sclerosing cholangitis, obstructive choledocholithiasis, carcinoma of the bile duct, cholestasis , and chronic hepatitis C viral infection...
  
  
• Drug-induced pruritus
  Drug-induced pruritus
  Drug-induced pruritus is itchiness of the skin caused by medication, a pruritic reaction that is generalized.-References:...
  
  
• Hydroxyethyl starch-induced pruritus
  Hydroxyethyl starch-induced pruritus
  Hydroxyethyl starch-induced pruritus is an intense itching, lasting for as long as one year, occurring following hydroxyethyl starch intravenous infusion for vascular insufficiency....
  
  
• Lichen simplex chronicus
  Lichen simplex chronicus
  Lichen simplex chronicus is a skin disorder characterized by chronic itching and scratching. The constant scratching causes thick, leathery, brownish skin.- Causes :...
  
   (Neurodermatitis)
• Prion pruritus
  Prion pruritus
  Prion pruritus is the intense itching during the prodromal period of the Creutzfeldt-Jakob disease....
  
  
• Prurigo nodularis
  Prurigo nodularis
  Prurigo nodularis is a skin disease characterised by pruritic nodules which usually appear on the arms or legs. Patients often present with multiple excoriated lesions caused by scratching...
  
  
• Prurigo pigmentosa
  Prurigo pigmentosa
  Prurigo pigmentosa is a rare skin condition of unknown cause, characterized by the sudden onset of erythematous papules that leave a reticulated hyperpigmentation when they heal.-References:...
  
  
• Prurigo simplex
• Pruritus ani
  Pruritus ani
  Pruritus ani is the irritation of the skin at the exit of the rectum, known as the anus, causing the desire to scratch. The intensity of anal itching increases from moisture, pressure, and rubbing caused by clothing and sitting...
  
  
• Pruritus scroti
  Pruritus scroti
  Pruritus scroti is itchiness of the scrotum that may be secondary to an infectious cause.-References:...
  
  
• Pruritus vulvae
  Pruritus vulvae
  Pruritus vulvae is pruritus of the vulva, which is the counterpart of pruritus scroti, and may be caused by many different causes.- Causes :This condition is a symptom of an underlying condition more often than it is a primary condition....
  
  
• Puncta pruritica
  Puncta pruritica
  Puncta pruritica consists of one or two itchy spots in clinically normal skin, sometimes followed by the appearance of seborrheic keratoses at exactly the same site....
  
   (Itchy points)
• Scalp pruritus
  Scalp pruritus
  Scalp pruritus is an itchiness of the scalp, particularly common in elderly persons....
  
  
• Senile pruritus
  Senile pruritus
  - References :...
  
  
• Uremic pruritus
  Uremic pruritus
  Uremic pruritus is caused by chronic renal failure and is the most common internal systemic cause of pruritus.- Pathogenesis of Uremic Pruritus :...
  
   (Renal pruritus)

Psoriasis

Psoriasis

Psoriasis

Psoriasis is an autoimmune disease that appears on the skin. It occurs when the immune system mistakes the skin cells as a pathogen, and sends out faulty signals that speed up the growth cycle of skin cells. Psoriasis is not contagious. However, psoriasis has been linked to an increased risk of...

 is a common, chronic, and recurrent inflammatory

Inflammation

Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli and to initiate the healing process...

 disease of the skin characterized by circumscribed, erythematous, dry, scaling plaques.

• Annular pustular psoriasis
  Annular pustular psoriasis
  Annular pustular psoriasis is a rare variant of pustular psoriasis, having an annular, or circinate, lesion morphology that may appear at the onset of pustular psoriasis, with a tendency to spread and form enlarged rings....
  
  
• Drug-induced psoriasis
  Drug-induced psoriasis
  Drug-induced psoriasis may be induced by beta-blockers, lithium, antimalarials, terbinafine, calcium channel blockers, captopril, glyburide, granulocyte colony-stimulating factor, interleukins, interferons, and lipid-lowering drugs....
  
  
• Exanthematic pustular psoriasis
  Exanthematic pustular psoriasis
  Exanthematic pustular psoriasis is a cutaneous condition characterized by an acute eruption of small pustules, abruptly appearing and disappearing in a few days. It usually follows an infection or may occur as a result of administration of specific medications....
  
  
• Generalized pustular psoriasis
  Generalized pustular psoriasis
  Generalized pustular psoriasis is an extremely rare type of [psoriasis] that can present in a variety of forms. Unlike the most general and common forms of psoriasis, GPP usually covers the entire body and with pus-filled blisters rather than plaques. GPP can present at any age, but is rarer in...
  
   (Pustular psoriasis of von Zumbusch)
• Guttate psoriasis
  Guttate psoriasis
  Guttate psoriasis is a type of psoriasis that presents as small lesions over the upper trunk and proximal extremities; it is found frequently in young adults...
  
   (Eruptive psoriasis)
• Inverse psoriasis
  Inverse psoriasis
  Inverse psoriasis is a form of psoriasis that selectively and often exclusively involves the folds, recesses, and flexor surfaces such as the ears, axillae, groins, inframammary folds, navel, intergluteal crease, penis, lips, and webspaces....
  
  
• Keratoderma blennorrhagica
  Keratoderma blennorrhagica
  Keratoderma blennorrhagica are skin lesions commonly found on the palms and soles but which may spread to the scrotum, scalp and trunk also, and which resemble psoriasis....
  
   (Keratoderma blennorrhagicum)
• Localized pustular psoriasis
  Localized pustular psoriasis
  Localized pustular psoriasis presents as two distinct conditions that must be considered separate from generalized psoriasis, and without systemic symptoms, these two distinct varieties being pustulosis palmaris et plantaris and acrodermatitis continua....
  
  
• Napkin psoriasis
  Napkin psoriasis
  Napkin psoriasis, or psoriasis in the diaper area, is characteristically seen in infants between two and eight months of age....
  
  
• Psoriasis vulgaris (Chronic stationary psoriasis, Plaque-like psoriasis)
• Psoriatic arthritis
  Psoriatic arthritis
  Psoriatic arthritis is a type of inflammatory arthritis that, according to the National Psoriasis Foundation, will develop in up to 30 percent of people who have the chronic skin condition psoriasis...
  
  
• Psoriatic erythroderma
  Psoriatic erythroderma
  Psoriatic erythroderma represents a generalized form of psoriasis that affects all body sites, including the face, hands, feet, nails, trunk, and extremities....
  
   (Erythrodermic psoriasis)
• Seborrheic-like psoriasis
  Seborrheic-like psoriasis
  Seborrheic-like psoriasis is a skin condition characterized by psoriasis with an overlaping seborrheic dermatitis....
  
   (Sebopsoriasis, Seborrhiasis)

Reactive neutrophilic

Reactive neutrophilic cutaneous conditions

Reactive neutrophilic dermatoses

Reactive neutrophilic dermatoses are a spectrum of conditions mediated by neutrophils, and typically associated with underlying diseases, such as inflammatory bowel disease and hematologic malignancy....

 constitute a spectrum of disease mediated by neutrophils, and typically associated with underlying diseases, such as inflammatory bowel disease

Inflammatory bowel disease

In medicine, inflammatory bowel disease is a group of inflammatory conditions of the colon and small intestine. The major types of IBD are Crohn's disease and ulcerative colitis.-Classification:...

 and hematologic

Hematology

Hematology, also spelled haematology , is the branch of biology physiology, internal medicine, pathology, clinical laboratory work, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases...

 malignancy.

• Acute erythema nodosum
  Acute erythema nodosum
  Acute erythema nodosum is a skin condition, a reactive process commonly associated with a streptococcal infection which, in children, is by far the most common precipitant.- See also :* Chronic erythema nodosum* Erythema nodosum...
  
  
• Bowel-associated dermatosis–arthritis syndrome
  Bowel-associated dermatosis–arthritis syndrome
  Bowel-associated dermatosis–arthritis syndrome is characterized by diarrhea with resultant malabsorption, arthritis and skin lesions, and it is seen in patients who have undergone intestinal bypass surgery, have blind loops of bowel following surgery,...
  
   (Bowel bypass syndrome, Bowel bypass syndrome without bowel bypass, Intestinal bypass arthritis–dermatitis syndrome)
• Marshall syndrome
  Marshall syndrome
  Marshall syndrome is a genetic disorder of the connective tissue which can cause hearing loss. The three most common areas to be affected are the eyes, joints and the mouth and facial structures...
  
  
• Neutrophilic dermatosis of the dorsal hands
  Neutrophilic dermatosis of the dorsal hands
  Neutrophilic dermatosis of the dorsal hands is a skin condition that presents with edematous pustular or ulcerative nodules or plaques localized to the dorsal hands....
  
   (Pustular vasculitis of the dorsal hands)
• Neutrophilic eccrine hidradenitis
  Neutrophilic eccrine hidradenitis
  Neutrophilic eccrine hidradenitis usually is a cutaneous complication of chemotherapy, but it also can occur because of other reasons. It consist of fever and non specific skin lesions. It is rare, and self-limited...
  
  
• Pyoderma gangrenosum
  Pyoderma gangrenosum
  Pyoderma gangrenosum is a disease that causes tissue to become necrotic, causing deep ulcers that usually occur on the legs. When they occur, they can lead to chronic wounds. Ulcers usually initially look like small bug bites or papules, and they progress to larger ulcers. Though the wounds...
  
  
• Pyogenic arthritis–pyoderma gangrenosum–acne syndrome (PAPA syndrome)
• Rheumatoid neutrophilic dermatitis
  Rheumatoid neutrophilic dermatitis
  Rheumatoid neutrophilic dermatitis is a cutaneous condition associated with rheumatoid arthritis....
  
   (Rheumatoid neutrophilic dermatosis)
• Superficial granulomatous pyoderma
  Superficial granulomatous pyoderma
  Superficial granulomatous pyoderma is a cutaneous condition, a variant of pyoderma gangrenosum characterized by a localized superficial vegetative or ulcerative lesion, which usually follows trauma, such as surgery....
  
  
• Sweet's syndrome (Acute febrile neutrophilic dermatosis)
• Sweet's syndrome-like dermatosis
• Vesicopustular dermatosis
  Vesicopustular dermatosis
  Vesicopustular dermatosis is a cutaneous condition characterized by neutrophils, and associated with bowel disorders....
  
  

Recalcitrant palmoplantar eruptions

Recalcitrant palmoplantar eruptions are skin conditions of the palm

Hand

A hand is a prehensile, multi-fingered extremity located at the end of an arm or forelimb of primates such as humans, chimpanzees, monkeys, and lemurs...

s and soles

Sole (foot)

The sole is the bottom of the foot.In humans the sole of the foot is anatomically referred to as the plantar aspect. The equivalent surface in ungulates is the hoof.- Human sole :...

 which are resistant to treatment.

• Dermatitis repens
  Dermatitis repens
  Dermatitis repens is a rare, sterile, pustular eruption of the fingers and toes that slowly extends...
  
   (Acrodermatitis continua, Acrodermatitis continua of Hallopeau, Acrodermatitis continua suppurativa Hallopeau, Acrodermatitis perstans, Dermatitis repens Crocker, Hallopeau's acrodermatitis, Hallopeau's acrodermatitis continua, Pustular acrodermatitis)
• Infantile acropustulosis
  Infantile acropustulosis
  Infantile acropustulosis is an intensely itchy vesicopustular eruption of the hands and feet.Involvement of scabies has been suggested....
  
   (Acropustulosis of infancy)
• Palmoplantar pustulosis (Persistent palmoplantar pustulosis, Pustular psoriasis of the Barber type, Pustular psoriasis of the extremities, Pustulosis of palms and soles, Pustulosis palmaris et plantaris)
• Pustular bacterid
  Pustular bacterid
  Pustular bacterid is a skin condition characterized by a symmetric, grouped, vesicular or pustular eruption on the palms and soles marked by exacerbations and remissions over long periods of time....
  
  

Resulting from errors in metabolism

Skin conditions resulting from errors in metabolism are caused by enzymatic

Enzyme

Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 defects that lead to an accumulation or deficiency of various cellular components, including, but not limited to, amino acid

Amino acid

Amino acids are molecules containing an amine group, a carboxylic acid group and a side-chain that varies between different amino acids. The key elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen...

s, carbohydrate

Carbohydrate

A carbohydrate is an organic compound with the empirical formula ; that is, consists only of carbon, hydrogen, and oxygen, with a hydrogen:oxygen atom ratio of 2:1 . However, there are exceptions to this. One common example would be deoxyribose, a component of DNA, which has the empirical...

s, and lipid

Lipid

Lipids constitute a broad group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins , monoglycerides, diglycerides, triglycerides, phospholipids, and others...

s.

• Acute intermittent porphyria
  Acute intermittent porphyria
  Acute intermittent porphyria is a rare autosomal dominant metabolic disorder affecting the production of heme, the oxygen-binding prosthetic group of hemoglobin. It is characterized by a deficiency of the enzyme porphobilinogen deaminase. Acute intermittent porphyria is the second most common...
  
  
• Adrenoleukodystrophy
  Adrenoleukodystrophy
  Adrenoleukodystrophy is a rare, inherited disorder that leads to progressive brain damage, failure of the adrenal glands and eventually death. ALD is a disease in a group of genetic disorders called leukodystrophies, whose chief feature is damage to myelin...
  
   (Schilder's disease)
• Alkaptonuria
  Alkaptonuria
  Alkaptonuria is a rare inherited genetic disorder of phenylalanine and tyrosine metabolism. This is an autosomal recessive condition that is due to a defect in the enzyme homogentisate 1,2-dioxygenase , which participates in the degradation of tyrosine...
  
  
• Aminolevulinic acid dehydratase deficiency porphyria
  Aminolevulinic acid dehydratase deficiency porphyria
  Aminolevulinic acid dehydratase deficiency porphyria is a cutaneous condition, disease can present during early childhood with acute neurologic symptoms that resemble those encountered in acute intermittent porphyria...
  
   (Doss porphyria, Plumboporphyria)
• B-mannosidase deficiency
  B-mannosidase deficiency
  B-mannosidase deficiency is a rare autosomal recessive condition characterized by angiokeratomas similar to those seen with Fabry disease....
  
  
• Carotenosis
  Carotenosis
  Carotenaemia is the presence in blood of the yellow pigment carotene from excessive intake of carrots or other vegetables containing the pigment resulting in increased serum carotenoids. It can lead to subsequent yellow-orange discoloration and their subsequent deposition in the outermost layer...
  
  
• Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome (CADASIL syndrome)
• Cerebrotendinous xanthomatosis
• Citrullinemia
  Citrullinemia
  Citrullinemia, also called citrullinuria, is an autosomal recessive urea cycle disorder that causes ammonia and other toxic substances to accumulate in the blood....
  
  
• Congenital erythropoietic porphyria (Gunther's disease)
• Diabetic bulla
  Diabetic bulla
  A diabetic bulla is a cutaneous condition characterized by a noninflammatory, spontaneous, painless blister, often in acral locations , seen in diabetic patients....
  
   (Bullosis diabeticorum, Bullous eruption of diabetes mellitus)
• Diabetic cheiroarthropathy
  Diabetic cheiroarthropathy
  Diabetic cheiroarthropathy is a cutaneous condition characterized by thickened skin and limited joint mobility of the hands and fingers, leading to flexion contractures, a condition associated with diabetes mellitus. and it is observed in roughly 30% of diabetic patients with longstanding disease.*...
  
  
• Diabetic dermopathy
  Diabetic dermopathy
  Diabetic dermopathy is a type of skin lesion seen in people with diabetes mellitus. It is characterized by dull-red papules that progress to well-circumscribed, small, round, atrophic hyperpigmented skin lesions on the shins. It is the most common of several diabetic skin conditions....
  
   (Shin spots)
• Dystrophic calcinosis cutis
  Dystrophic calcinosis cutis
  Dystrophic calcinosis cutis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus, and occurs in a preexisting skin lesion of inflammatory process....
  
  
• Eruptive xanthoma
• Erythropoietic protoporphyria
  Erythropoietic protoporphyria
  Erythropoietic protoporphyria is a relatively mild form of porphyria, although very painful, which arises from a deficiency in the enzyme ferrochelatase, leading to abnormally high levels of protoporphyrin in the tissue...
  
   
• Fabry disease (Anderson–Fabry disease, Angiokeratoma corporis diffusum)
• Familial alpha-lipoprotein deficiency (Tangier disease)
• Familial amyloid polyneuropathy
  Familial amyloid polyneuropathy
  Familial amyloid polyneuropathy , also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis or Corino de Andrade's disease, is an autosomal dominant neurodegenerative disease. It is a form of paramyloidosis, and was first identified and described by Portuguese neurologist...
  
  
• Familial apoprotein CII deficiency
• Familial combined hyperlipidemia (Multiple-type hyperlipoproteinemia)
• Familial defective apolipoprotein B-100
• Familial dysbetalipoproteinemia
  Familial dysbetalipoproteinemia
  Familial dysbetalipoproteinemia is a condition characterized by increased LDL, triglyceride, and cholesterol levels, and decreased HDL levels...
  
   (Broad beta disease, Remnant removal disease)
• Familial hypertriglyceridemia
  Familial hypertriglyceridemia
  Familial hypertriglyceridemia is an autosomal dominant condition occurring in approximately 1% of the population. Triglyceride levels, but not cholesterol, are elevated as a result of excess hepatic production of VLDL or heterozygous LPL deficiency. Unlike familial hypercholesterolemia, there is no...
  
  
• Farber disease
  Farber disease
  Farber disease is an extremely rare autosomal recessive lysosomal storage disease that cause an accumulation of fatty material lipids leading to abnormalities in the joints, liver, throat, tissues and central nervous system...
  
   (Fibrocytic dysmucopolysaccharidosis, Lipogranulomatosis)
• Fucosidosis
  Fucosidosis
  Fucosidosis, also called alpha-l-fucosidase deficiency, is a rare autosomal recessive lysosomal storage disease in which the enzyme fucosidase is not properly used in the cells to break down fucose. This enzyme normally cleaves long sugar chains known as oligosaccharides in the lysosome...
  
  
• Gaucher's disease
  Gaucher's disease
  Gaucher's disease is a genetic disease in which a fatty substance accumulates in cells and certain organs.Gaucher's disease is the most common of the lysosomal storage diseases. It is caused by a hereditary deficiency of the enzyme glucosylceramidase. The enzyme acts on the fatty acid...
  
  
• Gout
  Gout
  Gout is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis—a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected . However, it may also present as tophi, kidney stones, or urate...
  
   (Podagra, Urate crystal arthropathy, Urate deposition disease)
• Hartnup disease
  Hartnup disease
  Hartnup disease is an autosomal recessive metabolic disorder affecting the absorption of nonpolar amino acids...
  
   (Pellagra-like dermatosis)
• Hemodialysis-associated amyloidosis
• Hepatoerythropoietic porphyria
  Hepatoerythropoietic porphyria
  Hepatoerythropoietic porphyria is a very rare form of hepatic porphyria caused by a disorder in both genes which code Uroporphyrinogen III decarboxylase .It has a similar presentation to porphyria cutanea tarda , but with earlier onset...
  
  
• Hereditary coproporphyria
  Hereditary coproporphyria
  Hereditary coproporphyria is a type of acute porphyria that is associated with a deficiency of the enzyme coproporphyrinogen III oxidase....
  
  
• Hereditary gelsolin amyloidosis
  Hereditary gelsolin amyloidosis
  Hereditary gelsolin amyloidosis is a cutaneous condition inherited in an autosomal dominant fashion....
  
  
• Heredofamilial amyloidosis
  Heredofamilial amyloidosis
  Heredofamilial amyloidosis is an inherited condition that may be characterized by systemic or localized deposition of amyloid in body tissues....
  
  
• Hunter syndrome
  Hunter syndrome
  Hunter syndrome, or mucopolysaccharidosis Type II, is a lysosomal storage disease caused by a deficient enzyme, iduronate-2-sulfatase . The syndrome is named after physician Charles A. Hunter , who first described it in 1917...
  
  
• Hurler syndrome
  Hurler syndrome
  Hurler syndrome, also known as mucopolysaccharidosis type I , Hurler's disease, also gargoylism, is a genetic disorder that results in the buildup of glycosaminoglycans due to a deficiency of alpha-L iduronidase, an enzyme responsible for the degradation of mucopolysaccharides in lysosomes...
  
   (Gargoylism, Mucopolysaccharidosis type I)
• Hurler–Scheie syndrome
  Hurler–Scheie syndrome
  Hurler–Scheie syndrome is a cutaneous condition, also characterized by mild mental retardation and corneal clouding....
  
   (Mucopolysaccharidosis type I H-S)
• Hyaluronidase deficiency
  Hyaluronidase deficiency
  Hyaluronidase deficiency is a condition caused by mutations in HYAL1, and characterized by multiple soft-tissue masses....
  
   (Mucopolysaccharidosis type IX)
• Iatrogenic calcinosis cutis
  Iatrogenic calcinosis cutis
  Iatrogenic calcinosis cutis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus inadvertently introduced by a medical procedure....
  
  
• Idiopathic scrotal calcinosis
  Idiopathic scrotal calcinosis
  Idiopathic scrotal calcinosis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus occurring on the scrotum....
  
   (Idiopathic calcified nodules of the scrotum)
• Lafora disease
  Lafora disease
  Lafora disease, also called Lafora progressive myoclonic epilepsy or MELF , is a fatal autosomal recessive genetic disorder characterized by the presence of inclusion bodies, known as Lafora bodies, within neurons and the cells of the heart, liver, muscle, and skin.Most patients with this disease...
  
  
• Lesch–Nyhan syndrome (Juvenile gout)
• Lichen amyloidosis
  Lichen amyloidosis
  Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, typically appearing bilaterally on the shins....
  
  
• Limited joint mobility
  Limited Joint Mobility
  Limited Joint Mobility, or LJM, is a complication of Type 1 Diabetes. It was one of the earliest known complications, first documented in 1974 ....
  
  
• Lipoid proteinosis (Hyalinosis cutis et mucosae, Urbach–Wiethe disease)
• Lipoprotein lipase deficiency
  Lipoprotein lipase deficiency
  Lipoprotein lipase deficiency is caused by a mutation in the gene which codes lipoprotein lipase....
  
   (Chylomicronemia, Chylomicronemia syndrome)
• Macular amyloidosis
  Macular amyloidosis
  Macular amyloidosis is a cutaneous condition characterized by itchy, brown, rippled macules usually located on the interscapular region of the back.- See also :* Amyloidosis* Primary cutaneous amyloidosis* List of cutaneous conditions...
  
   
• Maroteaux–Lamy syndrome (Mucopolysaccharidosis type VI)
• Medication-induced hyperlipoproteinemia
  Medication-induced hyperlipoproteinemia
  Medication-induced hyperlipoproteinemia is a condition that results from the decreasing of lipoprotein lipase activity resulting in eruptive xanthomas.- See also :* Normolipoproteinemic xanthomatosis* Cerebrotendinous xanthomatosis* Skin lesion...
  
  
• Metastatic calcinosis cutis
  Metastatic calcinosis cutis
  Metastatic calcinosis cutis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus, and associated with an internal malignancy....
  
  
• Milia-like calcinosis
  Milia-like calcinosis
  Milia-like calcinosis is a cutaneous condition characterized by small, milia-like lesions that develop on the dorsal surface of the hands and the face....
  
  
• Morquio's disease (Mucopolysaccharidosis type IV)
• Necrobiosis lipoidica
  Necrobiosis lipoidica
  Necrobiosis lipoidica is a necrotising skin condition that usually occurs in patients with diabetes but can also be associated with Rheumatoid Arthritis. In the former case it may be called necrobiosis lipoidica diabeticorum ...
  
   (Necrobiosis lipoidica diabeticorum)
• Niemann–Pick disease
• Nodular amyloidosis
  Nodular amyloidosis
  Nodular amyloidosis is a rare cutaneous condition characterized by nodules that involve the acral areas....
  
  
• Nodular xanthoma
• Normolipoproteinemic xanthomatosis
  Normolipoproteinemic xanthomatosis
  Normolipoproteinemic xanthomatosis is a cutaneous condition characterized by a xanthoma in the presence of normal cholesterol and lipoprotein levels....
  
  
• Obstructive liver disease (Xanthomatous biliary cirrhosis)
• Ochronosis
  Ochronosis
  Ochronosis is the syndrome caused by the accumulation of homogentisic acid in connective tissues. The phenomenon was first described by Rudolf Virchow in 1865. The condition was named after the yellowish discoloration of the tissue seen on microscopic examination...
  
  
• Osteoma cutis
  Osteoma cutis
  Osteoma cutis is a cutaneous condition characterized by the presence of bone within the skin in the absence of a preexisting or associated lesion....
  
  
• Palmar xanthoma
• Phenylketonuria
  Phenylketonuria
  Phenylketonuria is an autosomal recessive metabolic genetic disorder characterized by a mutation in the gene for the hepatic enzyme phenylalanine hydroxylase , rendering it nonfunctional. This enzyme is necessary to metabolize the amino acid phenylalanine to the amino acid tyrosine...
  
  
• Phytosterolemia (Sitosterolemia)
• Porphyria cutanea tarda
  Porphyria cutanea tarda
  Porphyria cutanea tarda is the most common subtype of porphyria. The disorder results from low levels of the enzyme responsible for the fifth step in heme production. Heme is a vital molecule for all of the body's organs...
  
  
• Primary cutaneous amyloidosis
  Primary cutaneous amyloidosis
  Primary cutaneous amyloidosis is a form of amyloidosis associated with oncostatin M receptor. This type of amyloidosis has been divided into the following types:* Macular amyloidosis* Lichen amyloidosis* Nodular amyloidosis...
  
  
• Primary systemic amyloidosis
  Primary systemic amyloidosis
  Primary systemic amyloidosis is a disease that involves the mesenchymal tissue, the tongue, heart, gastrointestinal tract, and skin....
  
  
• Prolidase deficiency
  Prolidase deficiency
  Prolidase deficiency is a rare autosomal recessiveinborn error of metabolism.Although metabolism of the amino acid proline is affected by the enzyme prolidase, this disorder is not to be confused with hyperprolinemia, which involves different enzymatyic pathways related to proline metabolism...
  
  
• Pseudoporphyria
  Pseudoporphyria
  Pseudoporphyria is a bullous photosensitivity that clinically and histologically mimics porphyria cutanea tarda. The difference is that no abnormalities in urine or serum porphyrin is noted on laboratories...
  
   (Pseudoporphyria cutanea tarda)
• Sanfilippo syndrome
  Sanfilippo syndrome
  Sanfilippo syndrome, or Mucopolysaccharidosis III is a rare autosomal recessive lysosomal storage disease. It is caused by a deficiency in one of the enzymes needed to break down the glycosaminoglycan heparan sulfate .Although undegraded heparan sulfate is the primary stored substrate,...
  
  
• Scheie syndrome
  Scheie syndrome
  Scheie syndrome ") is less severe version of Hurler's disease. It is a condition characterized by corneal clouding, facial dysmorphism, and normal lifespan but unlike Hurler's, disease has normal intellect and ....
  
   (Mucopolysaccharidosis type I S)
• Secondary cutaneous amyloidosis
  Secondary cutaneous amyloidosis
  Secondary cutaneous amyloidosis is a skin condition that occurs following PUVA therapy and in benign and malignant cutaneous neoplasms in which deopsits of amyloid may be found....
  
  
• Secondary systemic amyloidosis
  Secondary systemic amyloidosis
  Secondary systemic amyloidosis is a condition that involves the adrenal gland, liver, spleen, and kidney as a result of amyloid deposition due to a chronic disease such as Behçet's disease, ulcerative colitis, etc.- See also :* Amyloidosis...
  
  
• Sialidosis
  Sialidosis
  Mucolipidosis type I or sialidosis is an inherited lysosomal storage disease that results from a deficiency of the enzyme sialidase. The lack of this enzyme results in an abnormal accumulation of complex carbohydrates known as mucopolysaccharides, and of fatty substances known as mucolipids...
  
  
• Sly syndrome
  Sly syndrome
  Sly syndrome, also called Mucopolysaccharidosis Type VII or MPS, is an autosomal recessive lysosomal storage disease characterized by a deficiency of the enzyme β-glucuronidase, a lysosomal enzyme. Sly syndrome belongs to a group of disorders known as mucopolysaccharidoses, which are lysosomal...
  
   (Mucopolysaccharidosis type VII)
• Subepidermal calcified nodule
  Subepidermal calcified nodule
  Subepidermal calcified nodule is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus, occurring most frequently as one or a few skin lesions on the scalp or face of children....
  
   (Solitary congenital nodular calcification, Winer's nodular calcinosis)
• Transient erythroporphyria of infancy
  Transient erythroporphyria of infancy
  Transient erythroporphyria of infancy is a cutaneous condition reported in infants exposed to blue lights for the treatment of indirect hyperbilirubinemia characterized by marked purpura in skin exposed to the UV light....
  
   (Purpuric phototherapy-induced eruption)
• Traumatic calcinosis cutis
  Traumatic calcinosis cutis
  Traumatic calcinosis cutis is a cutaneous condition characterized by calcification of the skin resulting from the deposition of calcium and phosphorus often resulting from occupational exposure, as in cases reported in oil-field workers and coal miners....
  
  
• Tuberoeruptive xanthoma (Tuberous xanthoma)
• Tumoral calcinosis
  Tumoral calcinosis
  Tumoral calcinosis is a skin condition characterized by calcification of a pre-existing skin tumor ; it presents as large subcutaneous masses. The original tumor may or may not disappear leaving behind a calcified nodule that may eventually ossify ....
  
  
• Variegate porphyria
  Variegate porphyria
  Variegate porphyria is an autosomal dominant porphyria that can have acute symptoms along with symptoms that affect the skin...
  
   (Mixed hepatic porphyria, Mixed porphyria, South African genetic porphyria, South African porphyria)
• Verruciform xanthoma
  Verruciform xanthoma
  Verruciform xanthoma is an uncommon benign lesion that has a verruciform appearance, but it may appear polypoid, papillomatous, or sessile. Usually found on the oral mucosa of middle-aged persons, verruciform xanthomas have also been reported on the scrotum and penis of middle-aged to elderly...
  
  
• Waxy skin
  Waxy skin
  Waxy skin is a cutaneous condition observed in roughly 50% of diabetic patients with longstanding disease....
  
  
• Wilson's disease
  Wilson's disease
  Wilson's disease or hepatolenticular degeneration is an autosomal recessive genetic disorder in which copper accumulates in tissues; this manifests as neurological or psychiatric symptoms and liver disease...
  
   (Hepatolenticular degeneration)
• Xanthelasma palpebrarum (Xanthelasma)
• Xanthoma diabeticorum
  Xanthoma diabeticorum
  Xanthoma diabeticorum is a cutaneous condition that may result in young persons who are unresponsive to insulin....
  
  
• Xanthoma planum (Plane xanthoma)
• Xanthoma striatum palmare
  Xanthoma striatum palmare
  Xanthoma striatum palmare is a cutaneous condition characterized by xanthomas of the palmar creases which are almost diagnostic for dysbetalipoproteinemia....
  
  
• Xanthoma tendinosum (Tendinous xanthoma)
• Xanthoma tuberosum

Resulting from physical factors

Skin conditions resulting from physical factors occur from a number of causes, including, but not limited to, hot and cold temperatures, friction

Friction

Friction is the force resisting the relative motion of solid surfaces, fluid layers, and/or material elements sliding against each other. There are several types of friction:...

, and moisture

Moisture

Humidity is the amount of moisture the air can hold before it rains. Moisture refers to the presence of a liquid, especially water, often in trace amounts...

.

• Abrasion
• Acrocyanosis
  Acrocyanosis
  Acrocyanosis is persistent blue or cyanotic discoloration of the extremities, most commonly occurring in the hands, although it also occurs in the feet and distal parts of face....
  
  
• Actinic prurigo
  Actinic prurigo
  Actinic prurigo is a not uncommon sunlight-induced, pruritic, papular or nodular skin eruption.-Causes:The cause for actinic prurigo is unknown, however researchers believe that the protein in...
  
   (Familial polymorphous light eruption of American Indians, Hereditary polymorphous light eruption of American Indians, Hutchinson's summer prurigo, Hydroa aestivale)
• Benign summer light eruption
  Benign summer light eruption
  Benign summer light eruption is a cutaneous condition, and a name used in continental Europe, and particularly France, to describe a clinically short-lived, itchy, papular eruption particularly affecting young women after several hours of sunbathing at the beginning of summer or on sunny vacations....
  
  
• Beryllium granuloma
  Beryllium granuloma
  Beryllium granulomas is a skin condition caused by granulomatous inflammation of the skin which may follow accident laceration, usually in the occupational setting....
  
  
• Black heel and palm (Black heel, Calcaneal petechiae, Chromidrose plantaire, Post-traumatic punctate intraepidermal hemorrhage, Tache noir, Talon noir)
• Callus
  Callus
  A callus is an especially toughened area of skin which has become relatively thick and hard in response to repeated friction, pressure, or other irritation. Rubbing that is too frequent or forceful will cause blisters rather than allow calluses to form. Since repeated contact is required, calluses...
  
   (Callosity, Clavus, Corn, Heloma, Heloma durum, Heloma molle, Intractable plantar keratosis, Tyloma)
• Carbon stain
  Carbon stain
  Carbon stains are a skin condition characterized by a discoloration of the skin from embedded carbon, usually occurring in children from careless use of firearms or firecrackers, or from puncture wound by a pencil, which may leave a permanent black mark of embedded graphite, easily mistaken for...
  
   
  
• Chilblains (Pernio, Perniosis)
• Chronic actinic dermatitis
  Chronic actinic dermatitis
  Chronic actinic dermatitis is a condition where a subject's skin becomes inflamed due to a reaction to sunlight or artificial light...
  
   (Actinic reticuloid, Chronic photosensitivity dermatitis, Persistent light reactivity, Photosensitive eczema)
• Colloid milium
  Colloid milium
  Colloid milium is a skin condition characterized by a translucent, flesh-colored, or slightly yellow 1- to 5-mm papule.- Treatment :There is no entirely successful treatment for colloid milium. Attempted treatments with varying results include:* cryotherapy...
  
  
• Coma blister
  Coma blister
  Coma blisters are a cutaneous condition characterized by tense bullae at sites of maximal pressure....
  
  
• Coral cut
  Coral cut
  Coral cuts are a severe type of skin injury that may occur from the cuts of coral skeletons....
  
  
• Delayed blister
  Delayed blister
  Delayed blisters are a cutaneous condition observed weeks to months after the initial healing of second-degree thermal burns, donor sites of split-thickness skin grafts, and recipient sites of split-thickness skin grafts....
  
  
• Dermatosis neglecta
  Dermatosis neglecta
  Dermatosis neglecta is a skin condition in which accumulation of sebum, keratin, sweat, dirt and debris leads to a localized patch of skin discoloration or a wart-like plaque...
  
  
• Edema blister
  Edema blister
  Edema blisters are a cutaneous condition that develop in patients with an acute exacerbation of chronic edema, particularly of the lower extremities, and in the setting of anasarca....
  
   (Edema bulla, Hydrostatic bulla, Stasis blister)
• Electrical burn
  Electrical burn
  An electrical burn is a burn that results from electricity passing through the body causing rapid injury. Approximately 1,000 deaths per year due to electrical injures are reported in the United States, with a mortality rate of 3-5%. Electrical burns differ from thermal or chemical burns in that...
  
  
• Equestrian perniosis
  Equestrian perniosis
  Equestrian perniosis is a skin condition that presents on the lateral thighs of women equestrians who ride on cold damp days....
  
  
• Erythema ab igne
  Erythema ab igne
  Erythema ab igne refers to skin that is reddened due to long-term exposure to infrared radiation. The term is derived from Latin and means "redness from fire".Erythema ab igne is a skin reaction caused by exposure to heat...
  
   (Fire stains, Toasted skin syndrome)
• Erythrocyanosis crurum
  Erythrocyanosis crurum
  Erythrocyanosis crurum is a skin condition, a variant of acrocyanosis caused by chronic exposure to cold....
  
  
• Favre–Racouchot syndrome
  Favre–Racouchot syndrome
  Favre–Racouchot syndrome is a disorder consisting of multiple open comedones that occurs in skin damaged by sunlight, especially under and lateral of the eyes. The comedones are widened openings for hair follicles and sebaceous glands filled with horny material....
  
   (Favre–Racouchot disease, Nodular cutaneous elastosis with cysts and comedones)
• Foreign body reaction
• Fracture blister
  Fracture blister
  Fracture blisters occur on skin overlying a fractured bone, and fractures complicated by the development of overlying blisters remain a clinical dilemma in orthopedics....
  
  
• Friction blister
  Friction blister
  Friction blisters are a skin condition that may occur at sites of combined pressure and friction, and may be enhanced by heat and moisture, characterized by vesicles or bullae....
  
  
• Frostbite
  Frostbite
  Frostbite is the medical condition where localized damage is caused to skin and other tissues due to extreme cold. Frostbite is most likely to happen in body parts farthest from the heart and those with large exposed areas...
  
  
• Garrod's pad
  Garrod's pad
  Garrod's pads is a cutaneous condition characterized by calluses on dorsal aspect of proximal interphalangeal joints of left index and middle fingers, seen in viola players....
  
   (Violinist's viola pad)
• Harpist's finger
  Harpist's finger
  Harpist's fingers are a cutaneous condition characterized by the repetative playing of the harp....
  
  
• Heel stick wound
  Heel stick wound
  Heel stick wounds are a cutaneous condition characterized by a break in the skin caused by neonatal heel prick....
  
  
• Heat edema
  Heat edema
  Heat edema is a cutaneous condition characterized by dependent edema from vasodilatory pooling....
  
  
• Hot tar burn
• Hunan hand syndrome
  Hunan hand syndrome
  Hunan hand syndrome is a cutaneous condition and commonly among those who remove the skins from large batches of roasted chili peppers....
  
   (Chili burn)
• Hydroa vacciniforme
  Hydroa vacciniforme
  Hydroa vacciniforme is a skin condition, a very rare, chronic photodermatitis with onset in childhood. It is seen in children under 10 years of age, and it disappears at puberty...
  
   (Bazin's hydroa vacciniforme)
• Jogger's nipple
  Jogger's nipple
  Fissure of the nipple, also known as jogger's nipple, is a condition that can be caused by friction that can result in soreness, dryness or irritation to, or bleeding of, one or both nipples during and/or following running or other physical exercise...
  
  
• Juvenile spring eruption
  Juvenile spring eruption
  Juvenile spring eruption is a cutaneous condition that affected the helices of the ears, particularly in boys because their ears are relatively more exposed to sunlight....
  
  
• Kairo cancer
  Kairo cancer
  Kairo cancer is a cutaneous condition that may develop due to hydrocarbon-fueled heat exposure from coal-fired clothing warmers....
  
  
• Kang cancer
  Kang cancer
  Kang cancer is a cutaneous condition that may develop due to hydrocarbon-fueled heat exposure from sleeping on coal-fire-heated bricks....
  
  
• Kangri ulcer
  Kangri ulcer
  Kangri ulcers are a cutaneous condition prevalent among the poorer classes of Kashmir, and a consequence of wearing warm embers....
  
  
• Lightning burn
  Lightning burn
  Lightning burns are a cutaneous condition, a type of electrical burn following a lightning strike on a human, characterized by a unique pattern of skin lesions after a lightning strike is the "lightning print," "feathering" or "Lichtenberg figures."...
  
  
• Loop mark
  Loop mark
  Loop marks are a cutaneous condition and perhaps the single most characteristic finding in child abuse....
  
  
• Magnetic resonance imaging burn
  Magnetic resonance imaging burn
  Magnetic resonance imaging burn is a cutaneous condition characterized by first-, second- or third-degree burns due to metal or wire contact with skin, creating a closed-loop conduction system....
  
   (MRI burn)
• Mercury granuloma
  Mercury granuloma
  Mercury granulomas is the result of mercury exposure, a skin condition characterized by foreign-body giant cell reaction....
  
  
• Miliaria crystallina (Miliaria crystalline, Sudamina)
• Miliaria profunda
  Miliaria profunda
  Miliaria profunda is a skin condition characterized by non-pruritic, flesh-colored, deep-seated, whitish papules....
  
   (Mammillaria)
• Miliaria pustulosa
  Miliaria pustulosa
  Miliaria pustulosa is a skin condition, a type of miliaria, that is preceded by another dermatitis that has produced injury, destruction, or blocking of the sweat duct....
  
  
• Miliaria rubra
  Miliaria rubra
  Miliaria rubra is a skin condition that appears as discrete, extremely pruritic, erythematous papulovesicles accompanied by a sensation of prickling, burning, or tingling...
  
   (Heat rash, Prickly heat)
• Narcotic dermopathy
  Narcotic dermopathy
  Narcotic dermopathy is a skin condition caused by the injection of drugs intravenously, resulting in thrombosed, cordlike, thickened veins at the site of injection....
  
  
• Occlusion miliaria
  Occlusion miliaria
  Occlusion miliaria is a skin condition that is accompanied by anhidrosis and increased heat-stress susceptibility, all after the application of extensive polyethylene film occlusion for 48 hours or longer....
  
  
• Painful fat herniation
  Painful fat herniation
  Painful fat herniation is a rare cause of painful feet due to fat herniations through the thin fascial layers of the weight-bearing parts of the heel....
  
   (Painful piezogenic pedal papules, Piezogenic papules)
• Peat fire cancer
  Peat fire cancer
  Peat fire cancer is a cutaneous condition that may develop on the shins of women due to hydrocarbon-fueled heat exposure from coal-fired clothing warmers....
  
  
• Photoaging
  Photoaging
  Photoaging or photoageing is a term used for the characteristic changes induced by chronic UVA and UVB exposure. Tretinoin is the best studied retinoid in the treatment of photoaging...
  
   (Dermatoheliosis)
• Photosensitivity with HIV infection
  Photosensitivity with HIV infection
  Photosensitivity with HIV infection is a skin condition resembling polymorphous light eruption, actinic prurigo, or chronic actinic dermatitis, seen in about 5% of HIV-infected people....
  
  
• Phototoxic tar dermatitis
  Phototoxic tar dermatitis
  Phototoxic tar dermatitis results from coal tar, creosote, crude coal tar, or pitch, in conjunction with sunlight exposure, which induces a sunburn reaction associated with severe burning sensation....
  
  
• Phytophotodermatitis
  Phytophotodermatitis
  Phytophotodermatitis is a chemical reaction which makes skin hypersensitive to ultraviolet light. It is frequently mistaken for hereditary conditions such as atopic dermatitis or chemical burns, but it is caused by contact with the photosensitizing compounds found naturally in some plants and...
  
   (Berloque dermatitis)
• Pinch mark
  Pinch mark
  Pinch marks are a cutaneous condition, and when on the ears or in the genital region of male children may be suggestive of child abuse....
  
  
• Polymorphous light eruption
  Polymorphous Light Eruption
  Polymorphous light eruption , or polymorphic light eruption , is a skin condition caused by sunlight.- Types :Two subtypes have been described:*Juvenile spring eruption*Benign summer light eruption-Presentation:...
  
   (Polymorphic light eruption)
• Postmiliarial hypohidrosis
  Postmiliarial hypohidrosis
  Postmiliarial hypohidrosis is a skin condition that results from occlusion of sweat ducts and pores, and may be severe enough to impair an individual's ability to perform sustained work in a hot environment....
  
   
  
• Postoperative hematoma
  Postoperative hematoma
  Postoperative hematomas are a cutaneous condition characterized by a collection of blood below the skin, and result as a complication following surgery....
  
  
• Pressure ulcer (Decubitus ulcer)
• Pseudoacanthosis nigricans
  Pseudoacanthosis nigricans
  Pseudoacanthosis nigricans is a cutaneous condition that may be associated with heroin abuse....
  
  
• Pseudoverrucous papules and nodules
  Pseudoverrucous papules and nodules
  Pseudoverrucous papules and nodules are a skin condition characterized by striking 2- to 8-mm, shiny, smooth, red, moist, flat-topped, round skin lesions in the perianal area of children....
  
  
• Pulling boat hands
• PUVA-induced acrobullous dermatosis
  PUVA-induced acrobullous dermatosis
  PUVA-induced acrobullous dermatosis is a cutaneous condition characterized by the sudden occurrence of tense blisters, usually on the distal extremities, during long-term PUVA therapy...
  
  
• Runner's rump
  Runner's rump
  Runner's rump is a cutaneous condition characterized by a small ecchymoses in upper gluteal cleft caused by constant friction with each stride when running....
  
  
• Sclerosing lymphangiitis
  Sclerosing lymphangiitis
  Sclerosing lymphangiitis is a skin condition characterized by a cordlike structure encircling the coronal sulcus of the penis, or running the length of the shaft, that has been attributed to trauma during vigorous sexual play....
  
  
• Silica granuloma
  Silica granuloma
  Silica granulomas are a skin condition which may be caused by automobile and other types of accidents which produces tattooing of dirt into the skin that then induces the granuloma formation.- References :...
  
  
• Silicone granuloma
  Silicone granuloma
  Silicone granulomas are a skin condition that occur as a reaction to liquid silicones, and are characterized by the formation of nodules....
  
  
• Skin pop scar
• Skin track
• Slap mark
  Slap mark
  Slap marks are a cutaneous condition characterized by ecchymoses and may be a sign of child abuse....
  
  
• Solar erythema
  Solar erythema
  Solar erythema is a skin condition characterized by redness of the skin following exposure to ultraviolet light, not to be confused with sunburn....
  
  
• Soot tattoo
  Soot tattoo
  Soot tattoos are a cutaneous condition that may be a sign of drug abuse, a condition produced by injections of residual carbon on the needle after flaming of the tip....
  
  
• Subcutaneous emphysema
  Subcutaneous emphysema
  Subcutaneous emphysema, sometimes abbreviated SCE or SE and also called tissue emphysema, or Sub Q air, occurs when gas or air is present in the subcutaneous layer of the skin. Subcutaneous refers to the tissue beneath the cutis of the skin, and emphysema refers to trapped air...
  
  
• Sucking blister
  Sucking blister
  Sucking blisters are a cutaneous condition present at birth, and due to sucking of the affected areas in utero....
  
  
• Sunburn
  Sunburn
  A sunburn is a burn to living tissue, such as skin, which is produced by overexposure to ultraviolet radiation, commonly from the sun's rays. Usual mild symptoms in humans and other animals include red or reddish skin that is hot to the touch, general fatigue, and mild dizziness. An excess of UV...
  
  
• Surfer's knots
  Surfer's knots
  Surfer's knots are a cutaneous condition caused by chronic pressure over bony prominences leading to thick fibrotic nodules on knees, knuckles, dorsal feet, often seen with those who perform surfing, boxing, football, and marbles....
  
  
• Tattoo
  Tattoo
  A tattoo is made by inserting indelible ink into the dermis layer of the skin to change the pigment. Tattoos on humans are a type of body modification, and tattoos on other animals are most commonly used for identification purposes...
  
  
• Tennis toe
• Thermal burn
• Traumatic asphyxia
• Trench foot
  Trench foot
  Trench foot is a medical condition caused by prolonged exposure of the feet to damp, unsanitary, and cold conditions. It is one of many immersion foot syndromes...
  
  
• Tropical anhidrotic asthenia
  Tropical anhidrotic asthenia
  Tropical anhidrotic asthenia is a skin condition, a rare form of miliaria, with long-lasting poral occlusion, which produces anhidrosis and heat retention....
  
  
• Tropical immersion foot
  Tropical immersion foot
  Tropical immersion foot is a skin condition of the feet seen after continuous immersion of the feet in water or mud of temperature above 22 degrees Celsius for two to ten days....
  
   (Paddy foot, Paddy-field foot)
• Turf toe
  Turf toe
  A metatarsalphalangeal joint sprain is an injury to the joint and connective tissue between the foot and one of the toes. When the big toe is involved, it is known as "turf toe".-Causes:...
  
  
• Uranium dermatosis
  Uranium dermatosis
  Uranium dermatosis is a cutaneous condition characterized by an irritant contact dermatitis and skin burns due to exposure to uranium....
  
  
• UV-sensitive syndrome
  UV-sensitive syndrome
  UV-sensitive syndrome is a cutaneous condition inherited in an autosomal recessive fashion, characterized by photosensitivity and solar lentigines....
  
  
• Vibration white finger
  Vibration white finger
  Vibration white finger is a secondary form of Raynaud's syndrome, an industrial injury triggered by continuous use of vibrating hand-held machinery. Use of the term Vibration White Finger has generally been superseded by Hand-Arm Vibration Syndrome or HAVS...
  
   (Dead finger, Hand–arm vibration syndrome)
• Warm water immersion foot
  Warm water immersion foot
  Warm water immersion foot is a skin condition of the feet that results after exposure to warm, wet conditions for 48 hours or more, and is characterized by maceration, blanching, and wrinkling of the soles and sides of the feet....
  
  
• Weathering nodule of ear
  Weathering nodule of ear
  Weathering nodules of ear is a cutaneous condition seen on the helices of the ears of Caucasian men who have a history of significant cumulative sun exposure....
  
  
• Wrestler's ear (Cauliflower ear, Traumatic auricular hematoma)
• Zirconium granuloma
  Zirconium granuloma
  Zirconium granulomas are a skin condition characterized by a papular eruption involving the axillae, and are sometimes considered an allergic reaction to deodorant containing zirconium lactate....
  
  

Ionizing radiation-induced

Ionizing radiation-induced cutaneous conditions result from exposure to ionizing radiation

Ionizing radiation

Ionizing radiation is radiation composed of particles that individually have sufficient energy to remove an electron from an atom or molecule. This ionization produces free radicals, which are atoms or molecules containing unpaired electrons...

.

• Acute radiodermatitis
  Acute radiodermatitis
  Acute radiodermatitis occurs when an "erythema dose" of ionizing radiation is given to the skin, after which visible erythema appears up to 24hrs after. Radiation dermatitis generally manifests within a few weeks after the start of radiotherapy. Acute radiodermatitis, while presenting as red...
  
  
• Chronic radiation keratosis
  Chronic radiation keratosis
  A Chronic radiation keratosis is a precancerous keratotic skin lesion that may arise on the skin many years after exposure to ionizing radiation.- See also :* Radiation dermatitis* Radiation recall reaction* Radiation-induced erythema multiforme...
  
  
• Chronic radiodermatitis
  Chronic radiodermatitis
  Chronic radiodermatitis occurs with chronic exposure to "sub-erythema" doses of ionizing radiation over a prolonged period, producing varying degrees of damage to the skin and its underlying parts after a variable latent period of several months to several decades...
  
  
• Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy
  Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy
  Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy is a skin condition that occurs most often in women receiving cobalt radiotherapy for internal cancer....
  
  
• Fluoroscopy burn
  Fluoroscopy burn
  Fluoroscopy burns are a cutaneous condition, and may occur when fluoroscopy is repeatedly performed in patients with cardiovascular disease, resulting in radiation-induced injury....
  
  
• Radiation acne
  Radiation acne
  Radiation acne is a cutaneous condition characterized by comedo-like papules occurring at sites of previous exposure to therapeutic ionizing radiation, skin lesions that begin to appear as the acute phase of radiation dermatitis begins to resolve.- See also :...
  
  
• Radiation cancer
  Radiation cancer
  Radiation cancer may occur following ionizing radiation exposure following a latent period averaging 20 to 40 years. Various malignancies may develop, most frequency basal-cell carcinoma followed by squamous-cell carcinoma. Elevated risk is confined to the site of radiation exposure...
  
  
• Radiation dermatitis
  Radiation dermatitis
  Radiation dermatitis is a skin disease associated with prolonged exposure to ionizing radiation. Radiation dermatitis occurs to some degree in most patients receiving radiation therapy, with or without chemotherapy....
  
   (Radiodermatitis)
• Radiation recall reaction
  Radiation recall reaction
  Radiation recall reactions occur months to years after radiation treatment, a reaction that follows recent administration of a chemotherapeutic agent and occurs with the prior radiation port, characterized by features of radiation dermatitis...
  
  
• Radiation-induced erythema multiforme
  Radiation-induced erythema multiforme
  Radiation-induced erythema multiforme may occur when phenytoin is given prophylactically to neurosurgical patients who are receiving whole-brain therapy and systemic steroids....
  
  
• Radiation-induced hypertrophic scar
• Radiation-induced keloid
• Radiation-induced morphea

Urticaria and angioedema

Urticaria

Urticaria

Urticaria is a kind of skin rash notable for pale red, raised, itchy bumps. Hives is frequently caused by allergic reactions; however, there are many non-allergic causes...

 is a vascular reaction of the skin characterized by the appearance of wheals, which are firm, elevated swelling of the skin. Angioedema

Angioedema

Angioedema or Quincke's edema is the rapid swelling of the dermis, subcutaneous tissue, mucosa and submucosal tissues. It is very similar to urticaria, but urticaria, commonly known as hives, occurs in the upper dermis...

, which can occur alone or with
urticaria, is characterized by a well-defined, edematous swelling that involves subcutaneous tissues, abdominal organs, and/or upper airway.

• Acquired C1 esterase inhibitor deficiency
  Acquired C1 esterase inhibitor deficiency
  Acquired C1 esterase inhibitor deficiency presents with symptoms indistinguishable from hereditary angioedema, but generally with onset after the fourth decade of life.C4 levels are low and C3 levels are normal....
  
  
• Acute urticaria
  Acute urticaria
  Acute urticaria is defined as the presence of evanescent wheals which completely resolve within six weeks.Acute urticaria becomes evident a few minutes after the person has been exposed to an allergen. The outbreak of acute urticaria may last several weeks, but usually the hives are gone in six weeks...
  
  
• Adrenergic urticaria
  Adrenergic urticaria
  Adrenergic urticaria is a skin condition characterized by an eruption consisting of small red macules and papules with a pale halo, appearing within 10 to 15 min after emotional upset.- See also :* Aquagenic urticaria* Wheal* Urticaria* Skin lesion...
  
  
• Anaphylaxis
  Anaphylaxis
  Anaphylaxis is defined as "a serious allergic reaction that is rapid in onset and may cause death". It typically results in a number of symptoms including throat swelling, an itchy rash, and low blood pressure...
  
  
• Aquagenic urticaria
  Aquagenic urticaria
  Aquagenic urticaria, also known as water urticaria and aquagenous urticaria, is a rarely diagnosed form of physical urticaria. It is sometimes described as an allergy, although it is not a true histamine releasing allergic reaction like other forms of urticaria...
  
  
• Cholinergic urticaria
  Cholinergic urticaria
  Cholinergic urticaria is a subcategory of physical urticaria that is a skin rash brought on by a hypersensitive reaction to body heat...
  
  
• Chronic urticaria
  Chronic urticaria
  Chronic urticaria is defined as the presence of evanescent wheals which persist for greater than six weeks....
  
   (Ordinary urticaria)
• Cold urticaria
• Dermatographism (Dermographism)
• Episodic angioedema with eosinophilia (Gleich syndrome)
• Exercise urticaria
  Exercise urticaria
  Exercise urticaria is a form of urticaria that happens during or after exercise, e.g. jogging or running. Urticaria is an allergic reaction in the skin characterized by itching -- as well as possible rash, swelling or hives -- on the legs, arms, torso or neck...
  
   (Exercise-induced urticaria)
• Galvanic urticaria
  Galvanic urticaria
  Galvanic urticaria has been described after exposure to a galvanic device used to treat hyperhidrosis....
  
  
• Heat urticaria
  Heat urticaria
  Heat urticaria presents within five minutes after the skin has been exposed to heat above 43 degrees Celsius , with the exposed area becoming burned, stinging, and turning red, swollen, and indurated....
  
  
• Hereditary angioedema
  Hereditary angioedema
  Hereditary angioedema presents in the second to fourth decade, and is characterized by local swelling in subcutaneous tissues....
  
   (Quincke edema)
• Localized heat contact urticaria
  Localized heat contact urticaria
  Localized heat contact urticaria is a cutaneous condition, one of the rarest forms of urticaria, where within minutes of contact with heat from any source, itching and whealing occur at the precise site of contact, lasting up to 1 hour....
  
  
• Mast cell-independent urticaria
• Physical urticaria
  Physical urticaria
  Physical urticarias represent a distinct subgroup of the urticarias that are induced by an exogenous physical stimulus rather than occurring spontaneously.The most common form of physical urticaria is dermatographism....
  
  
• Primary cold contact urticaria
  Primary cold contact urticaria
  Primary cold contact urticaria is a cutaneous condition characterized by wheals, and occurs in rainy, windy weather, and after contact with cold objects, including ice cubes....
  
  
• Pressure urticaria
  Pressure urticaria
  Pressure urticaria is a physical urticaria caused by pressure applied to the skin, and is characterized by the development of swelling and pain that usually occurs 3 to 12 hours after local pressure has been applied....
  
   (Delayed pressure urticaria)
• Reflex cold urticaria
  Reflex cold urticaria
  Reflex cold urticaria is a cutaneous condition in which generalized cooling of the body induces widespread whealing....
  
  
• Schnitzler syndrome
  Schnitzler syndrome
  Schnitzler syndrome is a rare disease characterised by chronic hives and periodic fever, bone pain and joint pain , weight loss, malaise, fatigue, swollen lymph glands and enlarged spleen and liver....
  
  
• Secondary cold contact urticaria
  Secondary cold contact urticaria
  Secondary cold contact urticaria is a cutaneous condition characterized by wheals, due to serum abnormalities such as cryoglobulinemia or cryofibrinogenemia are extremely rare, and are then associated with other manifestations such as Raynaud's phenomenon or purpura....
  
  
• Solar urticaria
  Solar urticaria
  Solar urticaria is a rare condition in which exposure to ultraviolet or UV radiation, or sometimes even visible light, induces a case of urticaria or hives that can appear in both covered and uncovered areas of the skin. It is classified as a type of physical urticaria. The classification of...
  
  
• Systemic capillary leak syndrome
• Urticarial allergic eruption
  Urticarial allergic eruption
  Urticarial allergic eruption is a cutaneous condition characterized by annular or gyrate urticarial plaques that persist for greater than 24 hours....
  
  
• Urticaria-like follicular mucinosis
  Urticaria-like follicular mucinosis
  Urticaria-like follicular mucinosis is a rare cutaneous disorder that occurs primarily in middle-aged men....
  
  
• Vibratory angioedema
  Vibratory angioedema
  Vibratory angioedema is a form of physical urticaria that may be an inherited autosomal dominant trait, or may be acquired after prolonged occupational vibration exposure....
  
  

Vascular-related

Vascular-related cutaneous conditions result from dysfunction of the blood

Blood

Blood is a specialized bodily fluid in animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells....

 and/or blood vessel

Blood vessel

The blood vessels are the part of the circulatory system that transports blood throughout the body. There are three major types of blood vessels: the arteries, which carry the blood away from the heart; the capillaries, which enable the actual exchange of water and chemicals between the blood and...

s in the dermis, or lymphatics in the subcutaneous tissue

Subcutaneous tissue

The hypodermis, also called the hypoderm, subcutaneous tissue, or superficial fascia is the lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages...

s.

• Aagenaes syndrome
  Aagenaes syndrome
  A syndrome characterised by congenital hypoplasia of lymph vessels, which causes lymphedema of the legs and recurrent cholestasis in infancy, and slow progress to hepatic cirrhosis and giant cell hepatitis with fibrosis of the portal tracts....
  
  
• Acroangiodermatitis (Acroangiodermatitis of Mali, Mali acroangiodermatitis, Pseudo-Kaposi's sarcoma)
• Acute hemorrhagic edema of infancy
  Acute hemorrhagic edema of infancy
  Acute hemorrhagic edema of infancy is a skin condition that affects children under the age of two with a recent history of upper respiratory illness, a course of...
  
   (Acute hemorrhagic edema of childhood, Finkelstein's disease, Infantile postinfectious iris-like purpura and edema, Medallion-like purpura, Purpura en cocarde avec oedema, Seidlmayer syndrome)
• Arterial insufficiency ulcer
  Arterial insufficiency ulcer
  Arterial insufficiency ulcers are mostly localed on the lateral surface of the ankle or the distal digits.-Etiology:...
  
   (Ischemic ulcer)
• Arteriosclerosis obliterans
  Arteriosclerosis obliterans
  Arteriosclerosis obliterans is an occlusive arterial disease most prominently affecting the abdominal aorta and the small- and medium-sized arteries of the lower extremities, which may lead to absent dorsalis pedis, posterior tibial, and/or popliteal artery pulses.It is characterized by fibrosis of...
  
  
• Bier spots
  Bier spots
  Bier spots are small, light macules usually found on the arms and legs of young adults, in which the intervening skin may seem erthematous but blanches with pressure so that these light macules disappear. This is a benign physiologic vascular anomaly of no significance clinically....
  
  
• Blueberry muffin baby
  Blueberry muffin baby
  Blueberry muffin baby is a term used to describe the characteristic distributed purpura due to extramedullary hematopoiesis found in infants.It was originally considered characteristic of rubella, but is now considered to be potentially associated with many other conditions, such as cytomegalovirus...
  
  
• Bonnet–Dechaume–Blanc syndrome
  Bonnet–Dechaume–Blanc syndrome
  Bonnet–Dechaume–Blanc syndrome is a rare condition characterized by a vascular malformation extending from the craniofacial to the orbital regions and brain.It was characterized in 1938...
  
   (Wyburn–Mason syndrome)
• Bullous lymphedema
  Bullous lymphedema
  Bullous lymphedema is a skin condition that usually occurs with poorly controlled edema related to heart failure and fluid overload, and compression results in healing....
  
  
• Bullous small vessel vasculitis
  Bullous small vessel vasculitis
  Bullous small vessel vasculitis is a cutaneous condition in which patients with small vessel vasculitis will develop superimposed vesicles and bullae, especially on the distal extremities....
  
   (Bullous variant of small vessel vasculitis)
• Calciphylaxis
  Calciphylaxis
  Calciphylaxis is a syndrome of vascular calcification, thrombosis and skin necrosis. It is seen almost exclusively in patients with Stage 5 chronic kidney disease. It results in chronic non-healing wounds and is usually fatal. Calciphylaxis is a rare but serious disease. Calciphylaxis is one type...
  
   
• Cholesterol embolus (Warfarin blue toe syndrome)
• Cobb syndrome
  Cobb syndrome
  Cobb syndrome is a rare congenital disorder characterized by visible skin lesions with underlying spinal angiomas or arteriovenous malformations . The skin lesions of Cobb syndrome typically are present as port wine stains or angiomas, but reports exist of angiokeratomas, angiolipomas, and...
  
  
• Cryofibrinogenemic purpura
  Cryofibrinogenemic purpura
  Cryofibrinogenemic purpura is a skin condition that manifests as painful purpura with slow healing ulcerations and edema of both feet during winter months....
  
  
• Cryoglobulinemic purpura
  Cryoglobulinemic purpura
  Cryoglobulinemic purpura is a skin condition characterized by purpura and occurring most frequently in multiple myeloma and macroglobulinemia.- References :...
  
  
• Cryoglobulinemic vasculitis
  Cryoglobulinemic vasculitis
  Cryoglobulinemic vasculitis is a skin condition presenting in roughly 15% of people with a circulating cryoprecipitable protein....
  
  
• Cutaneous small-vessel vasculitis
  Cutaneous small-vessel vasculitis
  Cutaneous small-vessel vasculitis is inflammation of small blood vessels , characterized by palpable purpura. It is the most common vasculitis seen in clinical practice...
  
   (Cutaneous leukocytoclastic angiitis, Cutaneous leukocytoclastic vasculitis, Cutaneous necrotizing venulitis, Hypersensitivity angiitis)
• Deep venous thrombosis
• Disseminated intravascular coagulation
  Disseminated intravascular coagulation
  Disseminated intravascular coagulation , also known as disseminated intravascular coagulopathy or consumptive coagulopathy, is a pathological activation of coagulation mechanisms that happens in response to a variety of diseases. DIC leads to the formation of small blood clots inside the blood...
  
  
• Doucas and Kapetanakis pigmented purpura
• Drug-induced purpura
  Drug-induced purpura
  Drug-induced purpura is a skin condition that may be related to platelet destruction, vessel fragility, interference with platelet function, or vasculitis....
  
  
• Drug-induced thrombocytopenic purpura
  Drug-induced thrombocytopenic purpura
  Drug-induced thrombocytopenic purpura is a skin condition result from a low platelet count due to drug-induced anti-platelet antibodies caused by drugs such as heparin, sulfonamines, digoxin, quinine, and quinidine....
  
  
• Eczematid-like purpura of Doucas and Kapetanakis
  Eczematid-like purpura of Doucas and Kapetanakis
  Eczematid-like purpura of Doucas and Kapetanakis is a medical term for a lymphocytic capillaritis of unknown cause. Lesions consist of erythematous and purpuric macules which usually begin around the ankles, coalesce, and spread to involve the whole legs, and sometimes the trunk and upper extremities...
  
  
• Epidemic dropsy
  Epidemic dropsy
  Epidemic dropsy is a form of edema of extremities due to intoxication with Argemone mexicana .,..In Northern India, epidemic dropsy occurs as a food adulterant disease where use of mustard oil as cooking medium is common...
  
  
• Erythema elevatum diutinum
  Erythema elevatum diutinum
  Erythema elevatum diutinum is a form of vasculitis.It has been described as a paraneoplastic syndrome.- References :...
  
  
• Erythromelalgia
  Erythromelalgia
  Erythromelalgia, also known as Mitchell's disease , acromelalgia, red neuralgia, or erythermalgia, is a rare neurovascular peripheral pain disorder in which blood vessels, usually in the lower extremities , are episodically blocked , then become hyperemic and inflamed...
  
   (Acromelalgia, Erythermalgia)
• Factitial lymphedema
  Factitial lymphedema
  Factitial lymphedema is a skin condition produced by wrapping an elastic bandage, cord, or shirt around an extremity, and/or holding the extremity in a dependent and immobile state....
  
   (Hysterical edema)
• Fibrinolysis syndrome
  Fibrinolysis syndrome
  Fibrinolysis syndrome is characterized by an acute hemorrhagic state brought about by inability of the blood to clot, with massive hemorrhages into the skin producing blackish, purplish swellings and sloughing....
  
   (Defibrinating syndrome, Hypofibrinogenemia)
• Food-induced purpura
  Food-induced purpura
  Food-induced purpura is a skin condition that may result from ingestion of tartrazine dye, benzoates, and food containing Escherichia coli O157:H7....
  
  
• Generalized essential telangiectasia
  Generalized essential telangiectasia
  Generalized essential telangiectasia is characterized by the dilation of veins and capillaries over a large segment of the body without preceding or coexisting lesions, telengiectases that may be distributed over the entire body or be localized to some large area such as the legs, arms, or trunk....
  
   (General essential telangiectasia)
• Giant-cell arteritis
• Gougerot–Blum syndrome
  Gougerot–Blum syndrome
  Gougerot–Blum syndrome is a variant of Pigmented purpuric dermatitis, a skin condition characterized by minute, rust-colored to violaceous, lichenoid papules that tend to fuse into plaques of various hues...
  
   (Pigmented purpuric lichenoid dermatitis, Pigmented purpuric lichenoid dermatitis of Gougerot and Blum)
• Hematopoietic ulcer
  Hematopoietic ulcer
  Hematopoietic ulcers are those occurring with sickle cell anemia, Cooley anemia, congenital hemolytic anemia, polycythemia vera, thrombocytopenic purpura, macroglobulinemia, and cryoglobulinemia....
  
  
• Hennekam syndrome
  Hennekam syndrome
  Hennekam syndrome also known as Hennekam lymphangiectasia–lymphedema syndrome and intestinal lymphagiectasia–lymphedema–mental retardation syndrome is an autosomal recessive disorder consisting of intestinal lymphangiectasia, facial anomalies, peripheral lymphedema, and mild to moderate levels of...
  
   (Hennekam lymphangiectasia-lymphedema syndrome, Intestinal lymphagiectasia-lymphedema-mental retardation syndrome)
• Henoch–Schönlein purpura (Anaphylactoid purpura, Purpura rheumatica, Schönlein–Henoch purpura)
  
• Hereditary hemorrhagic telangiectasia
  Hereditary hemorrhagic telangiectasia
  Hereditary hemorrhagic telangiectasia , also known as Osler-Weber-Rendu disease and Osler-Weber-Rendu syndrome, is a genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver and brain.It may lead to nosebleeds, acute...
  
   (Osler's disease, Osler–Weber–Rendu disease)
• Idiopathic thrombocytopenic purpura
  Idiopathic thrombocytopenic purpura
  Idiopathic thrombocytopenic purpura is the condition of having an abnormally low platelet count of no known cause . As most incidents of ITP appear to be related to the production of antibodies against platelets, immune thrombocytopenic purpura or immune thrombocytopenia are terms also used to...
  
   (Autoimmune thrombocytopenic purpura, Werlhof's disease)
• IgA vasculitis
  IgA vasculitis
  IgA vasculitis is a cutaneous condition characterized by inflammatory retiform purpura....
  
  
• Kawasaki's disease (Mucocutaneous lymph node syndrome)
• Lichen aureus
  Lichen aureus
  Lichen aureus is a skin condition characterized by the sudden appearance of one or several golden or rust-colored, closely packed macules or lichenoid papules....
  
   (Lichen purpuricus)
• Livedo racemosa
  Livedo racemosa
  Livedo racemosa is a cutaneous condition characterized by a skin discoloration appearing as irregular-broken circles....
  
  
• Livedo reticularis
• Livedoid dermatitis (Embolia cutis medicamentosa, Nicolau syndrome)
• Livedoid vasculopathy (Atrophie blanche, Livedo reticularis with summer ulceration, Livedoid vasculitis, PURPLE syndrome, Segmental hyalinizing vasculitis)
• Lymphedema praecox
  Lymphedema praecox
  Lymphedema praecox is a condition characterized by swelling of the soft tissues in which an excessive amount of lymph has accumulated, and generally develops in females between the ages of nine and twenty-five.- See also :* Lymphedema...
  
  
• Lymphedema–distichiasis syndrome
• Maffucci syndrome
• Majocchi's disease
  Majocchi's disease
  Majocchi's disease is a skin condition characterized by bluish-red 1- to 3-cm annular patches composed of dark red telangiectases with petechiae.- See also :...
  
   (Purpura annularis telangiectodes, Purpura annularis telangiectodes of Majocchi)
• Malignant atrophic papulosis (Degos' disease)
• Marshall–White syndrome
  Marshall–White syndrome
  Marshall–White syndrome is a skin condition that consists of Bier spots associated with insomnia and tachycardia....
  
  
• Meige lymphedema
• Microscopic polyangiitis
  Microscopic polyangiitis
  Microscopic polyangiitis is an ill-defined autoimmune disease characterized by pauci-immune, necrotizing, small-vessel vasculitis without clinical or pathological evidence of necrotizing granulomatous inflammation.-Presentation:Because many different organ systems may be involved, a wide range of...
  
   (Microscopic polyarteritis, Microscopic polyarteritis nodosa)
• Mondor's disease
  Mondor's disease
  Mondor's disease is a rare condition which involves thrombophlebitis of the superficial veins of the breast and anterior chest wall...
  
   (Mondor's syndrome of superficial thrombophlebitis)
• Neuropathic ulcer
  Neuropathic ulcer
  Neuropathic ulcers are skin lesions that are common in diabetics. They are usually related to sensory loss in the lower extremities....
  
   (Mal perforans)
• Njolstad syndrome
  Njolstad syndrome
  Njolstad syndrome is a cutaneous condition that combines lymphedema of the limbs and face with congenital pulmonary lymphangiectasias....
  
  
• Nonne–Milroy–Meige syndrome (Hereditary lymphedema, Milroy disease)
• Obstructive purpura
  Obstructive purpura
  Obstructive purpura is a skin condition that may result from mechanical obstruction to circulation, with resulting stress on the small vessels leading to purpura....
  
  
• Orthostatic purpura
  Orthostatic purpura
  Orthostatic purpura is a skin condition that results from prolonged standing or even sitting with the legs lowered , which produced edema and a purpuric eruption on the lower extremities....
  
   (Stasis purpura)
• Painful bruising syndrome
  Painful bruising syndrome
  Painful bruising syndrome is an idiopathic trauma-induced condition seen in young to middle-aged women who sometimes manifest personality disorders....
  
   (Autoerythrocyte sensitization, Gardner–Diamond syndrome, Psychogenic purpura)
• Parkes Weber syndrome
  Parkes Weber syndrome
  Parkes Weber syndrome is a cutaneous condition characterized by an arteriovenous malformation that occurs in association with a cutaneous capillary malformation and skeletal or soft tissue hypertrophy.It may be associated with RASA1....
  
  
• Paroxysmal hand hematoma
  Paroxysmal hand hematoma
  Paroxysmal hand hematoma is a skin condition characterized by spontaneous focal hemorrhage into the palm or the volar surface of a finger, which results in transitory localized pain, followed by rapid swelling and localized blueish discoloration....
  
   (Achenbach syndrome)
• Paroxysmal nocturnal hemoglobinuria
  Paroxysmal nocturnal hemoglobinuria
  Paroxysmal nocturnal hemoglobinuria , sometimes referred to as Marchiafava-Micheli syndrome, is a rare, acquired, potentially life-threatening disease of the blood characterised by complement-induced intravascular hemolytic anemia , red urine and thrombosis...
  
  
• Polyarteritis nodosa
  Polyarteritis nodosa
  Polyarteritis nodosa is a vasculitis of medium & small-sized arteries, which become swollen and damaged from attack by rogue immune cells. Polyarteritis nodosa is also called Kussmaul disease or Kussmaul-Maier disease...
  
   (Panarteritis nodosa, Periarteritis nodosa)
• Postcardiotomy syndrome
  Postcardiotomy syndrome
  Postcardiotomy syndrome occurs two to three weeks after pericardiotomy, and is characterized by fever, pleuritis, pericarditis, or arthritis, together with petechiae on the skin and palate.. The cause is believed to be an autoimmune response against damaged cardiac tissue. This is supported by...
  
  
• Perinatal gangrene of the buttock
  Perinatal gangrene of the buttock
  Perinatal gangrene of the buttock is a skin condition similar to livedoid dermatitis, and is usually a complication of umbilical artery catheterization, exchange transfusion, or cord injections by means of a syringe....
  
  
• Pigmentary purpuric eruptions
  Pigmentary purpuric eruptions
  Pigmented purpuric dermatosis refers to one of the three major classes of skin conditions characterized by purpuric skin eruptions.Pigmented purpuric dermatosis are distinguished from other purpura by size and are most often...
  
   (Progressive pigmentary dermatosis, Progressive pigmenting purpura, Purpura pigmentosa chronica)
• Postinflammatory lymphedema
  Postinflammatory lymphedema
  Postinflammatory lymphedema is a condition characterized by swelling of the soft tissues in which an excessive amount of lymph has accumulated, and is caused by repeated bacterial infections....
  
  
• Postmastectomy lymphangiosarcoma (Stewart–Treves syndrome)
• Purpura fulminans
  Purpura fulminans
  Purpura fulminans is a haemorrhagic condition usually associated with sepsis or previous infection. It occurs mainly in babies and small children.It was first described by Guelliot in 1884.- Presentation :...
  
   (Purpura gangrenosa)
• Purpura secondary to clotting disorders
  Purpura secondary to clotting disorders
  Purpura secondary to clotting disorders are purpura which occur due to hereditary disorders of blood coagulation in which there is a deficiency or qualitative abnormality of a single coagulation factor, as in hemophilia or von Willebrand's disease....
  
  
• Purpuric agave dermatitis
  Purpuric agave dermatitis
  Purpuric agave dermatitis is a skin condition condition caused by Agave americana, a large, thick, long-leaved, subtropical plant....
  
   
  
• Raynaud phenomenon
• Raynaud's disease (Primary Raynaud's phenomenon)
• Reactive angioendotheliomatosis
  Reactive angioendotheliomatosis
  Reactive angioendotheliomatosis is a cutaneous condition characterized histologically by a dense proliferation of small capillaries....
  
  
• Schamberg's disease (Progressive pigmentary dermatosis of Schamberg, Purpura pigmentosa progressiva, Schamberg's purpura)
• Secondary lymphedema
  Secondary lymphedema
  Secondary lymphedema is a condition characterized by swelling of the soft tissues in which an excessive amount of lymph has accumulated, and is caused by certain malignant diseases such as Hodgkin's disease and Kaposi sarcoma....
  
  
• Septic thrombophlebitis
  Septic thrombophlebitis
  Septic thrombophlebitis is a cutaneous condition that results in tender, swollen extremities with or without erythema.Septic pelvic thrombophlebitis can be a puerperal complication.Treatment may involve heparin....
  
  
• Sinusoidal hemangioma
  Sinusoidal hemangioma
  Sinusoidal hemangioma is a condition, by something of a misnomer, a term for a lesion that is in fact a vascular malformation with various clinical presentations. This condition may present as nodules, often in the breast area or extremities, or as large firm bulging facial masses beneath...
  
  
• Sneddon's syndrome (Idiopathic livedo reticularis with cerebrovascular accidents)
• Solar purpura
  Solar purpura
  Solar purpura is a skin condition characterized by large, sharply outlined, 1- to 5-cm, dark purplish-red ecchymoses appearing on the dorsa of the forearms and less often the hands....
  
   (Actinic purpura, Senile purpura)
• Stasis dermatitis
  Stasis dermatitis
  Stasis dermatitis refers to the skin changes that occur in the leg as a result of "stasis" or blood pooling from insufficient venous return; the alternative name of varicose eczema comes from a common cause of this being varicose veins.Insufficient venous...
  
   (Congestion eczema, Gravitational dermatitis, Gravitational eczema, Stasis eczema, Varicose eczema)
• Superficial thrombophlebitis
  Superficial thrombophlebitis
  Superficial thrombophlebitis is an inflammation and thrombosis of superficial veins which presents as a painful induration with erythema, often in a linear or branching configuration forming cords.- References :...
  
  
• Takayasu arteritis (Aortic arch syndrome, Pulseless disease)
• Temporal arteritis
  Temporal arteritis
  Giant-cell arteritis or Horton disease is an inflammatory disease of blood vessels most commonly involving large and medium arteries of the head...
  
   (Cranial arteritis, Horton's disease)
• Thromboangiitis obliterans (Buerger's disease)
• Thrombotic thrombocytopenic purpura
  Thrombotic thrombocytopenic purpura
  Thrombotic thrombocytopenic purpura is a rare disorder of the blood-coagulation system, causing extensive microscopic thromboses to form in small blood vessels throughout the body...
  
   (Moschcowitz syndrome)
• Traumatic purpura
  Traumatic purpura
  Traumatic purpura is a skin condition resulting from trauma which produces ecchymoses of bizarre shapes suggestive of abuse....
  
  
• Trousseau's syndrome
• Unilateral nevoid telangiectasia
  Unilateral nevoid telangiectasia
  Unilateral nevoid telangiectasia presents with fine, threadlike telangiectases, developing in a unilateral, sometimes dermatomal, distribution, with the areas most often involved being the trigeminal and C3 and C4 or adjacent areas....
  
   (Nevoid telangiectasia)
• Urticarial vasculitis
  Urticarial vasculitis
  Urticarial vasculitis is a skin condition characterized by fixed urticarial lesions that appear histologically as a vasculitis.- Introduction :A rare autoimmune disease characterised by recurrent...
  
   (Chronic urticaria as a manifestation of venulitis, Hypocomplementemic urticarial vasculitis syndrome, Hypocomplementemic vasculitis, Unusual lupus-like syndrome)
• Venous insufficiency ulceration
  Venous insufficiency ulceration
  Venous insufficiency ulceration, as well as stasis dermatitis, is a skin condition that results from increased pressure in the venous system of the lower leg.- See also :* Arterial insufficiency ulcer* List of cutaneous conditions* Venous ulcer...
  
  
• Waldenström hyperglobulinemic purpura
  Waldenström hyperglobulinemic purpura
  Waldenström hyperglobulinemic purpura is a skin condition that presents with episodic showers of petechiae occurring on all parts of the body, most profusely on the lower extremities....
  
   (Purpura hyperglobulinemica)
• Waldenström macroglobulinemia
  Waldenström macroglobulinemia
  Waldenström's macroglobulinemia is cancer involving a subtype of white blood cells called lymphocytes. The main attributing antibody is Immunoglobulin M . WM is an "indolent lymphoma,"...
  
  
• Wegener granulomatosis
• Yellow nail syndrome
  Yellow nail syndrome
  Yellow nail syndrome is a very rare medical syndrome that includes pleural effusions, lymphoedema and yellow dystrophic nails. Approximately 40% will also have bronchiectasis. It is also associated with chronic sinusitis and persistent coughing...
  
   (Primary lymphedema associated with yellow nails and pleural effusion)

External links

• Skin Disorders at the Google Directory